Advances in Brief:

Charles H. Spruck, Heimo Strohmaier, Olle Sangfelt, Hannes M. Müller, Michael Hubalek, Elisabeth Müller-Holzner, Christian Marth, Martin Widschwendter, and Steven I. Reed

hCDC4 Gene Mutations in Endometrial Cancer
Cancer Res 2002 62: 4535-4539. [Abstract] [Full Text] [PDF]  

Pankaj Seth, Dale Porter, Jaana Lahti-Domenici, Yan Geng, Andrea Richardson, and Kornelia Polyak

Cellular and Molecular Targets of Estrogen in Normal Human Breast Tissue
Cancer Res 2002 62: 4540-4544. [Abstract] [Full Text] [PDF]  

Chandrasekhar Kanduri, Meena Kanduri, Liang Liu, Noopur Thakur, Susan Pfeifer, and Rolf Ohlsson

The Kinetics of Deregulation of Expression by de Novo Methylation of the H19 Imprinting Control Region in Cancer Cells
Cancer Res 2002 62: 4545-4548. [Abstract] [Full Text] [PDF]  

Masayuki Nakau, Hiroyuki Miyoshi, Michael F. Seldin, Masayuki Imamura, Masanobu Oshima, and Makoto M. Taketo

Hepatocellular Carcinoma Caused by Loss of Heterozygosity in Lkb1 Gene Knockout Mice
Cancer Res 2002 62: 4549-4553. [Abstract] [Full Text] [PDF]  

Maija Kiuru, Rainer Lehtonen, Johanna Arola, Reijo Salovaara, Heikki Järvinen, Kristiina Aittomäki, Jari Sjöberg, Tapio Visakorpi, Sakari Knuutila, Jorma Isola, Brett Delahunt, Riitta Herva, Virpi Launonen, Auli Karhu, and Lauri A. Aaltonen

Few FH Mutations in Sporadic Counterparts of Tumor Types Observed in Hereditary Leiomyomatosis and Renal Cell Cancer Families
Cancer Res 2002 62: 4554-4557. [Abstract] [Full Text] [PDF]  

Kazuaki Takaku, Jeffrey L. Wrana, Elizabeth J. Robertson, and Makoto M. Taketo

No Effects of Smad2 (Madh2) Null Mutation on Malignant Progression of Intestinal Polyps in Apc⁷¹⁶ Knockout Mice
Cancer Res 2002 62: 4558-4561. [Abstract] [Full Text] [PDF]  

Jenny Wilding, Josef Straub, Julie Bee, Michael Churchman, Walter Bodmer, Clive Dickson, Ian Tomlinson, and Mohammad Ilyas

Cyclin D1 Is Not an Essential Target of ß-Catenin Signaling During Intestinal Tumorigenesis, but It May Act as a Modifier of Disease Severity in Multiple Intestinal Neoplasia (Min) Mice
Cancer Res 2002 62: 4562-4565. [Abstract] [Full Text] [PDF]  

Donghui Li, Farzana L. Walcott, Ping Chang, Weiqing Zhang, Jijiang Zhu, Elaine Petrulis, Sonja E. Singletary, Aysegul A. Sahin, and Melissa L. Bondy

Genetic and Environmental Determinants on Tissue Response to in Vitro Carcinogen Exposure and Risk of Breast Cancer
Cancer Res 2002 62: 4566-4570. [Abstract] [Full Text] [PDF]  

Takeshi Taketani, Tomohiko Taki, Noriko Shibuya, Akira Kikuchi, Ryoji Hanada, and Yasuhide Hayashi

Novel NUP98-HOXC11 Fusion Gene Resulted from a Chromosomal Break within Exon 1 of HOXC11 in Acute Myeloid Leukemia with t(11;12)(p15;q13)
Cancer Res 2002 62: 4571-4574. [Abstract] [Full Text] [PDF]  

Michelle Y. Alfonso-De Matte, Hua Yang, Myria S. Evans, Jin Q. Cheng, and Patricia A. Kruk

Telomerase Is Regulated by c-Jun NH₂-Terminal Kinase in Ovarian Surface Epithelial Cells
Cancer Res 2002 62: 4575-4578. [Abstract] [Full Text] [PDF]  

Hidewaki Nakagawa, Hai Yan, Janet Lockman, Heather Hampel, Kenneth W. Kinzler, Bert Vogelstein, and Albert de la Chapelle

Allele Separation Facilitates Interpretation of Potential Splicing Alterations and Genomic Rearrangements
Cancer Res 2002 62: 4579-4582. [Abstract] [Full Text] [PDF]  

Laura Spahn, Robert Petermann, Christine Siligan, Johannes A. Schmid, Dave N. T. Aryee, and Heinrich Kovar

Interaction of the EWS NH₂ Terminus with BARD1 Links the Ewing’s Sarcoma Gene to a Common Tumor Suppressor Pathway
Cancer Res 2002 62: 4583-4587. [Abstract] [Full Text] [PDF]  

Bo Xu, Anne H. O’Donnell, Seong-Tae Kim, and Michael B. Kastan

Phosphorylation of Serine 1387 in Brca1 Is Specifically Required for the Atm-mediated S-Phase Checkpoint after Ionizing Irradiation
Cancer Res 2002 62: 4588-4591. [Abstract] [Full Text] [PDF]  

Biochemistry and Biophysics:

April C. Childs, Sharon L. Phaneuf, Amie J. Dirks, Tracey Phillips, and Christiaan Leeuwenburgh

Doxorubicin Treatment in Vivo Causes Cytochrome c Release and Cardiomyocyte Apoptosis, As Well As Increased Mitochondrial Efficiency, Superoxide Dismutase Activity, and Bcl-2:Bax Ratio
Cancer Res 2002 62: 4592-4598. [Abstract] [Full Text] [PDF]  

Carcinogenesis:

Marina Kochetkova, Olivia L. D. McKenzie, Anthony J. Bais, Julie M. Martin, Genevieve A. Secker, Ram Seshadri, Jason A. Powell, Susan J. Hinze, Alison E. Gardner, Hayley E. Spendlove, Nathan J. O’Callaghan, Anne-Marie Cleton-Jansen, Cees Cornelisse, Scott A. Whitmore, Joanna Crawford, Gabriel Kremmidiotis, Grant R. Sutherland, and David F. Callen

CBFA2T3 (MTG16) Is a Putative Breast Tumor Suppressor Gene from the Breast Cancer Loss of Heterozygosity Region at 16q24.3
Cancer Res 2002 62: 4599-4604. [Abstract] [Full Text] [PDF]  

Huijun Zhu and Nigel Gooderham

Neoplastic Transformation of Human Lung Fibroblast MRC-5 SV2 Cells Induced by Benzo[a]pyrene and Confluence Culture
Cancer Res 2002 62: 4605-4609. [Abstract] [Full Text] [PDF]  

Karsten Müller, Malte Siebert, Markus Heidt, Friedrich Marks, Peter Krieg, and Gerhard Fürstenberger

Modulation of Epidermal Tumor Development Caused by Targeted Overexpression of Epidermis-type 12S-Lipoxygenase
Cancer Res 2002 62: 4610-4616. [Abstract] [Full Text] [PDF]  

Clinical Investigations:

Nadia Harbeck, Ronald E. Kates, Maxime P. Look, Marion E. Meijer-van Gelder, Jan G. M. Klijn, Achim Krüger, Marion Kiechle, Fritz Jänicke, Manfred Schmitt, and John A. Foekens

Enhanced Benefit from Adjuvant Chemotherapy in Breast Cancer Patients Classified High-Risk according to Urokinase-type Plasminogen Activator (uPA) and Plasminogen Activator Inhibitor Type 1 (n = 3424)
Cancer Res 2002 62: 4617-4622. [Abstract] [Full Text] [PDF]  

Endocrinology:

Christel Péqueux, Christophe Breton, Jean-Claude Hendrick, Marie-Thérèse Hagelstein, Henri Martens, Rosita Winkler, Vincent Geenen, and Jean-Jacques Legros

Oxytocin Synthesis and Oxytocin Receptor Expression by Cell Lines of Human Small Cell Carcinoma of the Lung Stimulate Tumor Growth through Autocrine/Paracrine Signaling
Cancer Res 2002 62: 4623-4629. [Abstract] [Full Text] [PDF]  

Epidemiology and Prevention:

Eric J. Duell, Elizabeth A. Holly, Paige M. Bracci, John K. Wiencke, and Karl T. Kelsey

A Population-based Study of the Arg399Gln Polymorphism in X-Ray Repair Cross- Complementing Group 1 (XRCC1) and Risk of Pancreatic Adenocarcinoma
Cancer Res 2002 62: 4630-4636. [Abstract] [Full Text] [PDF]  

Experimental Therapeutics:

Daqing Li, Katherine V. Day, Shuzhen Yu, Gouli Shi, Shixi Liu, Ming Guo, Yun Xu, Sunil Sreedharan, and Bert W. O’Malley, Jr.

The Role of Adenovirus-mediated Retinoblastoma 94 in the Treatment of Head and Neck Cancer
Cancer Res 2002 62: 4637-4644. [Abstract] [Full Text] [PDF]  

Stephen R. Wedge, Donald J. Ogilvie, Michael Dukes, Jane Kendrew, Rosemary Chester, Janet A. Jackson, Sarah J. Boffey, Paula J. Valentine, Jon O. Curwen, Helen L. Musgrove, George A. Graham, Gareth D. Hughes, Andrew P. Thomas, Elaine S. E. Stokes, Brenda Curry, Graham H. P. Richmond, Peter F. Wadsworth, Alison L. Bigley, and Laurent F. Hennequin

ZD6474 Inhibits Vascular Endothelial Growth Factor Signaling, Angiogenesis, and Tumor Growth following Oral Administration
Cancer Res 2002 62: 4645-4655. [Abstract] [Full Text] [PDF]  

Kah-Whye Peng, Cynthia J. TenEyck, Evanthia Galanis, Kimberly R. Kalli, Lynn C. Hartmann, and Stephen J. Russell

Intraperitoneal Therapy of Ovarian Cancer Using an Engineered Measles Virus
Cancer Res 2002 62: 4656-4662. [Abstract] [Full Text] [PDF]  

Dirk M. Nettelbeck, Angel A. Rivera, Cristina Balagué, Ramon Alemany, and David T. Curiel

Novel Oncolytic Adenoviruses Targeted to Melanoma: Specific Viral Replication and Cytolysis by Expression of E1A Mutants from the Tyrosinase Enhancer/Promoter
Cancer Res 2002 62: 4663-4670. [Abstract] [Full Text] [PDF]  

Eric Edwards, Ling Geng, J. Tan, Halina Onishko, Edwin Donnelly, and Dennis E. Hallahan

Phosphatidylinositol 3-Kinase/Akt Signaling in the Response of Vascular Endothelium to Ionizing Radiation
Cancer Res 2002 62: 4671-4677. [Abstract] [Full Text] [PDF]  

YongJing Guo, Andrew P. Mazar, Jean-Jacques Lebrun, and Shafaat A. Rabbani

An Antiangiogenic Urokinase-derived Peptide Combined with Tamoxifen Decreases Tumor Growth and Metastasis in a Syngeneic Model of Breast Cancer
Cancer Res 2002 62: 4678-4684. [Abstract] [Full Text] [PDF]  

David Machover, Jacqueline Zittoun, Raphaël Saffroy, Philippe Broët, Stéphane Giraudier, Thierry Magnaldo, Emma Goldschmidt, Brigitte Debuire, Mireille Orrico, Yuying Tan, Zohar Mishal, Odile Chevallier, Carole Tonetti, Hélène Jouault, Ayhan Ulusakarya, Marie-Laure Tanguy, Gérard Metzger, and Robert M. Hoffman

Treatment of Cancer Cells with Methioninase Produces DNA Hypomethylation and Increases DNA Synthesis
Cancer Res 2002 62: 4685-4689. [Abstract] [Full Text] [PDF]  

Abhik Bandyopadhyay, Fernando López-Casillas, Shazli N. Malik, José Luis Montiel, Valentín Mendoza, Junhua Yang, and L-Z. Sun

Antitumor Activity of a Recombinant Soluble Betaglycan in Human Breast Cancer Xenograft
Cancer Res 2002 62: 4690-4695. [Abstract] [Full Text] [PDF]  

Immunology:

Jennifer Gillary Segal, Natalie C. Lee, Ying L. Tsung, Jeffrey A. Norton, and Kangla Tsung

The Role of IFN- in Rejection of Established Tumors by IL-12 : Source of Production and Target
Cancer Res 2002 62: 4696-4703. [Abstract] [Full Text] [PDF]  

Molecular Biology and Genetics:

Frederic G. Barr, Stephen J. Qualman, Michele H. Macris, Natalya Melnyk, Elizabeth R. Lawlor, Donna M. Strzelecki, Timothy J. Triche, Julia A. Bridge, and Poul H. B. Sorensen

Genetic Heterogeneity in the Alveolar Rhabdomyosarcoma Subset without Typical Gene Fusions
Cancer Res 2002 62: 4704-4710. [Abstract] [Full Text] [PDF]  

Siu Tim Cheung, Xin Chen, Xin Yuan Guan, San Yu Wong, Lai Shan Tai, Irene O. L. Ng, Samuel So, and Sheung Tat Fan

Identify Metastasis-associated Genes in Hepatocellular Carcinoma through Clonality Delineation for Multinodular Tumor
Cancer Res 2002 62: 4711-4721. [Abstract] [Full Text] [PDF]  

Donald R. Schwartz, Sharon L. R. Kardia, Kerby A. Shedden, Rork Kuick, George Michailidis, Jeremy M. G. Taylor, David E. Misek, Rong Wu, Yali Zhai, Danielle M. Darrah, Heather Reed, Lora H. Ellenson, Thomas J. Giordano, Eric R. Fearon, Samir M. Hanash, and Kathleen R. Cho

Gene Expression in Ovarian Cancer Reflects Both Morphology and Biological Behavior, Distinguishing Clear Cell from Other Poor-Prognosis Ovarian Carcinomas
Cancer Res 2002 62: 4722-4729. [Abstract] [Full Text] [PDF]  

David Grimwade, Susan V. Outram, Rajinder Flora, Stuart J. Ings, Arnold R. Pizzey, Ricardo Morilla, Charles F. Craddock, David C. Linch, and Ellen Solomon

The T-Lineage-affiliated CD2 Gene Lies within an Open Chromatin Environment in Acute Promyelocytic Leukemia Cells
Cancer Res 2002 62: 4730-4735. [Abstract] [Full Text] [PDF]  

Goberdhan P. Dimri, Jose-Luis Martinez, Jacqueline J. L. Jacobs, Petra Keblusek, Koji Itahana, Maarten van Lohuizen, Judith Campisi, David E. Wazer, and Vimla Band

The Bmi-1 Oncogene Induces Telomerase Activity and Immortalizes Human Mammary Epithelial Cells
Cancer Res 2002 62: 4736-4745. [Abstract] [Full Text] [PDF]  

Wen-Hong Shen, Jian-Hua Zhou, Suzanne R. Broussard, Gregory G. Freund, Robert Dantzer, and Keith W. Kelley

Proinflammatory Cytokines Block Growth of Breast Cancer Cells by Impairing Signals from a Growth Factor Receptor
Cancer Res 2002 62: 4746-4756. [Abstract] [Full Text] [PDF]  

Tumor Biology:

Fiona McGregor, Alessandra Muntoni, Janis Fleming, Judith Brown, David H. Felix, D. Gordon MacDonald, E. Kenneth Parkinson, and Paul R. Harrison

Molecular Changes Associated with Oral Dysplasia Progression and Acquisition of Immortality: Potential for Its Reversal by 5-Azacytidine
Cancer Res 2002 62: 4757-4766. [Abstract] [Full Text] [PDF]  

Jonathan D. Cheng, Roland L. Dunbrack, Jr., Matthildi Valianou, André Rogatko, R. Katherine Alpaugh, and Louis M. Weiner

Promotion of Tumor Growth by Murine Fibroblast Activation Protein, a Serine Protease, in an Animal Model
Cancer Res 2002 62: 4767-4772. [Abstract] [Full Text] [PDF]  

Muy-Teck Teh, Soon-Tee Wong, Graham W. Neill, Lucy R. Ghali, Michael P. Philpott, and Anthony G. Quinn

FOXM1 Is a Downstream Target of Gli1 in Basal Cell Carcinomas
Cancer Res 2002 62: 4773-4780. [Abstract] [Full Text] [PDF]  

Jan Pinkas and Philip Leder

MEK1 Signaling Mediates Transformation and Metastasis of EpH4 Mammary Epithelial Cells Independent of an Epithelial to Mesenchymal Transition
Cancer Res 2002 62: 4781-4790. [Abstract] [Full Text] [PDF]  

John M. Mariadason, Diego Arango, Georgia A. Corner, Maria J. Arañes, Kylie A. Hotchkiss, Wancai Yang, and Leonard H. Augenlicht

A Gene Expression Profile That Defines Colon Cell Maturation in Vitro
Cancer Res 2002 62: 4791-4804. [Abstract] [Full Text] [PDF] Supplementary Data  

Henri J. Huttunen, Carole Fages, Juha Kuja-Panula, Anne J. Ridley, and Heikki Rauvala

Receptor for Advanced Glycation End Products-binding COOH-terminal Motif of Amphoterin Inhibits Invasive Migration and Metastasis
Cancer Res 2002 62: 4805-4811. [Abstract] [Full Text] [PDF]  

Jiapeng Huang, William C. Powell, Ani C. Khodavirdi, Jian Wu, Takako Makita, Robert D. Cardiff, Michael B. Cohen, Henry M. Sucov, and Pradip Roy-Burman

Prostatic Intraepithelial Neoplasia in Mice with Conditional Disruption of the Retinoid X Receptor Allele in the Prostate Epithelium
Cancer Res 2002 62: 4812-4819. [Abstract] [Full Text] [PDF]  

Eva Geissinger, Christin Weisser, Petra Fischer, Manfred Schartl, and Claudia Wellbrock

Autocrine Stimulation by Osteopontin Contributes to Antiapoptotic Signalling of Melanocytes in Dermal Collagen
Cancer Res 2002 62: 4820-4828. [Abstract] [Full Text] [PDF]  

Jean-Christophe Saurin, Marjorie Fallavier, Bernard Sordat, Jean-Claude Gevrey, Jean-Alain Chayvialle, and Jacques Abello

Bombesin Stimulates Invasion and Migration of Isreco1 Colon Carcinoma Cells in a Rho-dependent Manner
Cancer Res 2002 62: 4829-4835. [Abstract] [Full Text] [PDF]  

Letters to the Editor:

János Fodor, Yutaka Kawakami, and Yukiko Kiniwa

Correspondence re: Y. Kiniwa et al., Tumor Antigens Isolated from a Patient with Vitiligo and T-Cell-infiltrated Melanoma. Cancer Res., 61: 7900–7907, 2001.
Cancer Res 2002 62: 4836-4837. [Full Text] [PDF]  

To see an article, click its [Full Text] link. To review many abstracts, check the boxes to the left of the titles you want, and click the 'Get All Checked Abstract(s)' button. To see one abstract at a time, click its [Abstract] link.