Advances in Brief:

Remco van Doorn, Remco Dijkman, Maarten H. Vermeer, Theo M. Starink, Rein Willemze, and Cornelis P. Tensen

A Novel Splice Variant of the Fas Gene in Patients with Cutaneous T-Cell Lymphoma
Cancer Res 2002 62: 5389-5392. [Abstract] [Full Text] [PDF]  

Abdel-Majid Khatib, Lucia Fallavollita, Edward V. Wancewicz, Brett P. Monia, and Pnina Brodt

Inhibition of Hepatic Endothelial E-Selectin Expression by C-raf Antisense Oligonucleotides Blocks Colorectal Carcinoma Liver Metastasis
Cancer Res 2002 62: 5393-5398. [Abstract] [Full Text] [PDF]  

Lewis Joe Stafford, Chunzhi Xia, Wenbin Ma, Yi Cai, and Mingyao Liu

Identification and Characterization of Mouse Metastasis-suppressor KiSS1 and Its G-Protein-coupled Receptor
Cancer Res 2002 62: 5399-5404. [Abstract] [Full Text] [PDF]  

Louise R. Howe, Kotha Subbaramaiah, Jay Patel, Jaime L. Masferrer, Aparna Deora, Clifford Hudis, Howard T. Thaler, William J. Muller, Baoheng Du, Anthony M. C. Brown, and Andrew J. Dannenberg

Celecoxib, a Selective Cyclooxygenase 2 Inhibitor, Protects against Human Epidermal Growth Factor Receptor 2 (HER-2)/neu-induced Breast Cancer
Cancer Res 2002 62: 5405-5407. [Abstract] [Full Text] [PDF]  

Alessandra Martini, Roberta La Starza, Hilde Janssen, Chrystèle Bilhou-Nabera, Anniek Corveleyn, Riet Somers, Ana Aventin, Robin Foà, Anne Hagemeijer, Christina Mecucci, and Peter Marynen

Recurrent Rearrangement of the Ewing’s Sarcoma Gene, EWSR1, or Its Homologue, TAF15, with the Transcription Factor CIZ/NMP4 in Acute Leukemia
Cancer Res 2002 62: 5408-5412. [Abstract] [Full Text] [PDF]  

Revati Koratkar, Ed Pequignot, Walter W. Hauck, and Linda D. Siracusa

The CAST/Ei Strain Confers Significant Protection against Apc^Min Intestinal Polyps, Independent of the Resistant Modifier of Min 1 (Mom1^R) Locus
Cancer Res 2002 62: 5413-5417. [Abstract] [Full Text] [PDF]  

Claudia Bolognesi, Rosangela Filiberti, Monica Neri, Emanuela Perrone, Eleonora Landini, Pier Aldo Canessa, Claudio Simonassi, Paolo Giuseppe Cerrano, Luciano Mutti, and Riccardo Puntoni

High Frequency of Micronuclei in Peripheral Blood Lymphocytes as Index of Susceptibility to Pleural Malignant Mesothelioma
Cancer Res 2002 62: 5418-5419. [Abstract] [Full Text] [PDF]  

Lin Pei, Yue Peng, Ying Yang, Xuefeng Bruce Ling, Winfried G. van Eyndhoven, Ken C. Q. Nguyen, Mark Rubin, Timothy Hoey, Scott Powers, and Jing Li

PRC17, a Novel Oncogene Encoding a Rab GTPase-activating Protein, Is Amplified in Prostate Cancer
Cancer Res 2002 62: 5420-5424. [Abstract] [Full Text] [PDF]  

Biochemistry and Biophysics:

Laurent Miccoli, Denis S. F. Biard, Christophe Créminon, and Jaime F. Angulo

Human Kin17 Protein Directly Interacts with the Simian Virus 40 Large T Antigen and Inhibits DNA Replication
Cancer Res 2002 62: 5425-5435. [Abstract] [Full Text] [PDF]  

Edouard I. Azzam, Sonia M. de Toledo, Douglas R. Spitz, and John B. Little

Oxidative Metabolism Modulates Signal Transduction and Micronucleus Formation in Bystander Cells from -Particle-irradiated Normal Human Fibroblast Cultures
Cancer Res 2002 62: 5436-5442. [Abstract] [Full Text] [PDF]  

Charles Mark Ensor, Frederick W. Holtsberg, John S. Bomalaski, and Mike A. Clark

Pegylated Arginine Deiminase (ADI-SS PEG_{20,000 mw}) Inhibits Human Melanomas and Hepatocellular Carcinomas in Vitro and in Vivo
Cancer Res 2002 62: 5443-5450. [Abstract] [Full Text] [PDF]  

Anthony L. Rinaldi, Mark A. Morse, Henry W. Fields, David A. Rothas, Ping Pei, Kapila A. Rodrigo, Robert J. Renner, and Susan R. Mallery

Curcumin Activates the Aryl Hydrocarbon Receptor yet Significantly Inhibits (-)-Benzo(a)pyrene-7R-trans-7,8-dihydrodiol Bioactivation in Oral Squamous Cell Carcinoma Cells and Oral Mucosa
Cancer Res 2002 62: 5451-5456. [Abstract] [Full Text] [PDF]  

Experimental Therapeutics:

Raquel Aloyz, Zhi-Yuan Xu, Vanessa Bello, Josée Bergeron, Fei-Yu Han, Yifei Yan, Areti Malapetsa, Moulay A. Alaoui-Jamali, Alessandra M. V. Duncan, and Lawrence Panasci

Regulation of Cisplatin Resistance and Homologous Recombinational Repair by the TFIIH Subunit XPD
Cancer Res 2002 62: 5457-5462. [Abstract] [Full Text] [PDF]  

Lei Zhang, Warren J. Gasper, Sanford A. Stass, Olga B. Ioffe, Myrtle A. Davis, and A. James Mixson

Angiogenic Inhibition Mediated by a DNAzyme That Targets Vascular Endothelial Growth Factor Receptor 2
Cancer Res 2002 62: 5463-5469. [Abstract] [Full Text] [PDF]  

Cheng Liu, Haining Huang, Fernando Doñate, Craig Dickinson, Richard Santucci, Amr El-Sheikh, Robert Vessella, and Thomas S. Edgington

Prostate-specific Membrane Antigen Directed Selective Thrombotic Infarction of Tumors
Cancer Res 2002 62: 5470-5475. [Abstract] [Full Text] [PDF]  

Kristian Pietras, Kristofer Rubin, Tobias Sjöblom, Elisabeth Buchdunger, Mats Sjöquist, Carl-Henrik Heldin, and Arne Östman

Inhibition of PDGF Receptor Signaling in Tumor Stroma Enhances Antitumor Effect of Chemotherapy
Cancer Res 2002 62: 5476-5484. [Abstract] [Full Text] [PDF]  

Nerissa Mendoza, Gail Lewis Phillips, Johnny Silva, Ralph Schwall, and Dineli Wickramasinghe

Inhibition of Ligand-mediated HER2 Activation in Androgen-independent Prostate Cancer
Cancer Res 2002 62: 5485-5488. [Abstract] [Full Text] [PDF]  

Immunology:

Milena Kalat, Zaruhi Küpcü, Susanne Schüller, Doris Zalusky, Margit Zehetner, Wolfgang Paster, and Tamás Schweighoffer

In Vivo Plasmid Electroporation Induces Tumor Antigen-specific CD8+ T-Cell Responses and Delays Tumor Growth in a Syngeneic Mouse Melanoma Model
Cancer Res 2002 62: 5489-5494. [Abstract] [Full Text] [PDF]  

Emmanouela Linardakis, Andrew Bateman, Vy Phan, Atique Ahmed, Michael Gough, Kenneth Olivier, Rick Kennedy, Fiona Errington, Kevin J. Harrington, Alan Melcher, and Richard Vile

Enhancing the Efficacy of a Weak Allogeneic Melanoma Vaccine by Viral Fusogenic Membrane Glycoprotein-mediated Tumor Cell-Tumor Cell Fusion
Cancer Res 2002 62: 5495-5504. [Abstract] [Full Text] [PDF]  

Suzanne L. Topalian, Monica I. Gonzales, Yvona Ward, Xiang Wang, and Rong-Fu Wang

Revelation of a Cryptic Major Histocompatibility Complex Class II-restricted Tumor Epitope in a Novel RNA-processing Enzyme
Cancer Res 2002 62: 5505-5509. [Abstract] [Full Text] [PDF]  

Francesca Schiavetti, Joëlle Thonnard, Didier Colau, Thierry Boon, and Pierre G. Coulie

A Human Endogenous Retroviral Sequence Encoding an Antigen Recognized on Melanoma by Cytolytic T Lymphocytes
Cancer Res 2002 62: 5510-5516. [Abstract] [Full Text] [PDF]  

Xiao-Feng Yang, Catherine J. Wu, Linyun Chen, Edwin P. Alyea, Christine Canning, Philip Kantoff, Robert J. Soiffer, Glenn Dranoff, and Jerome Ritz

CML28 Is a Broadly Immunogenic Antigen, Which Is Overexpressed in Tumor Cells
Cancer Res 2002 62: 5517-5522. [Abstract] [Full Text] [PDF]  

Molecular Biology and Genetics:

Alessandro Gozzetti, Elizabeth M. Davis, Rafael Espinosa, III, Anthony A. Fernald, John Anastasi, and Michelle M. Le Beau

Identification of Novel Cryptic Translocations Involving IGH in B-Cell Non-Hodgkin’s Lymphomas
Cancer Res 2002 62: 5523-5527. [Abstract] [Full Text] [PDF]  

Zhimin Tong, Gurmit Singh, and Andrew J. Rainbow

Sustained Activation of the Extracellular Signal-regulated Kinase Pathway Protects Cells from Photofrin-mediated Photodynamic Therapy
Cancer Res 2002 62: 5528-5535. [Abstract] [Full Text] [PDF]  

Tumor Biology:

Elisabeth Zenger, Nancy W. Abbey, Mark D. Weinstein, Leon Kapp, Jeremy Reis, Inessa Gofman, Carl Millward, Ron Gascon, Ahmed Elbaggari, Brian G. Herndier, and Michael S. McGrath

Injection of Human Primary Effusion Lymphoma Cells or Associated Macrophages into Severe Combined Immunodeficient Mice Causes Murine Lymphomas
Cancer Res 2002 62: 5536-5542. [Abstract] [Full Text] [PDF]  

Matthias Arlt, Charlotte Kopitz, Caroline Pennington, Katrina L. M. Watson, Hans-Willi Krell, Wolfram Bode, Bernd Gansbacher, Rama Khokha, Dylan R. Edwards, and Achim Krüger

Increase in Gelatinase-specificity of Matrix Metalloproteinase Inhibitors Correlates with Antimetastatic Efficacy in a T-Cell Lymphoma Model
Cancer Res 2002 62: 5543-5550. [Abstract] [Full Text] [PDF]  

Lene Uhrbom, Chengkai Dai, Joseph C. Celestino, Marc K. Rosenblum, Gregory N. Fuller, and Eric C. Holland

Ink4a-Arf Loss Cooperates with KRas Activation in Astrocytes and Neural Progenitors to Generate Glioblastomas of Various Morphologies Depending on Activated Akt
Cancer Res 2002 62: 5551-5558. [Abstract] [Full Text] [PDF]  

Tracy Vargo-Gogola, Barbara Fingleton, Howard C. Crawford, and Lynn M. Matrisian

Matrilysin (Matrix Metalloproteinase-7) Selects for Apoptosis-resistant Mammary Cells in Vivo
Cancer Res 2002 62: 5559-5563. [Abstract] [Full Text] [PDF]  

Yu-Po Lee, Edward M. Schwarz, Mark Davies, Mark Jo, Jeffrey Gates, Xuguang Zhang, Jing Wu, and Jay R. Lieberman

Use of Zoledronate to Treat Osteoblastic versus Osteolytic Lesions in a Severe-Combined-Immunodeficient Mouse Model
Cancer Res 2002 62: 5564-5570. [Abstract] [Full Text] [PDF]  

Manali S. Bendre, Dana Gaddy-Kurten, Thetsu Mon-Foote, Nisreen S. Akel, Robert A. Skinner, Richard W. Nicholas, and Larry J. Suva

Expression of Interleukin 8 and not Parathyroid Hormone-related Protein by Human Breast Cancer Cells Correlates with Bone Metastasis in Vivo
Cancer Res 2002 62: 5571-5579. [Abstract] [Full Text] [PDF]  

Sara A. Wickström, Kari Alitalo, and Jorma Keski-Oja

Endostatin Associates with Integrin ₅ß₁ and Caveolin-1, and Activates Src via a Tyrosyl Phosphatase-dependent Pathway in Human Endothelial Cells
Cancer Res 2002 62: 5580-5589. [Abstract] [Full Text] [PDF]  

Zhiheng He, Amin Ismail, Leonid Kriazhev, Gulzhakhan Sadvakassova, and Andrew Bateman

Progranulin (PC-Cell-derived Growth Factor/Acrogranin) Regulates Invasion and Cell Survival
Cancer Res 2002 62: 5590-5596. [Abstract] [Full Text] [PDF]  

Kristan Keyes, Karen Cox, Patti Treadway, Larry Mann, Chuan Shih, Margaret M. Faul, and Beverly A. Teicher

An In Vitro Tumor Model: Analysis of Angiogenic Factor Expression after Chemotherapy
Cancer Res 2002 62: 5597-5602. [Abstract] [Full Text] [PDF]  

Tomohiko Fukuda, Nobuaki Yoshida, Yuki Kataoka, Ri-ichiroh Manabe, Yoko Mizuno-Horikawa, Motohiko Sato, Kohji Kuriyama, Natsuo Yasui, and Kiyotoshi Sekiguchi

Mice Lacking the EDB Segment of Fibronectin Develop Normally but Exhibit Reduced Cell Growth and Fibronectin Matrix Assembly in Vitro
Cancer Res 2002 62: 5603-5610. [Abstract] [Full Text] [PDF]  

Kei Matsuda, Takenao Idezawa, Xue Juan You, Nayantara H. Kothari, Hung Fan, and Murray Korc

Multiple Mitogenic Pathways in Pancreatic Cancer Cells Are Blocked by a Truncated Epidermal Growth Factor Receptor
Cancer Res 2002 62: 5611-5617. [Abstract] [Full Text] [PDF]  

Meeting Report:

Francisco Lo Coco, Arthur Zelent, Adi Kimchi, Michael Carducci, Steve D. Gore, and Samuel Waxman

Progress in Differentiation Induction as a Treatment for Acute Promyelocytic Leukemia and Beyond
Cancer Res 2002 62: 5618-5621. [Abstract] [Full Text] [PDF]  

Correction:

Correction for vol 62, p 4383
Cancer Res 2002 62: 5624. [Full Text] [PDF]  

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