Advances in Brief:

Joshua R. Merok, Janice A. Lansita, James R. Tunstead, and James L. Sherley

Cosegregation of Chromosomes Containing Immortal DNA Strands in Cells That Cycle with Asymmetric Stem Cell Kinetics
Cancer Res 2002 62: 6791-6795. [Abstract] [Full Text] [PDF]  

Arndt Hartmann, Livia Zanardo, Tina Bocker-Edmonston, Hagen Blaszyk, Wolfgang Dietmaier, Robert Stoehr, John C. Cheville, Kerstin Junker, Wolf Wieland, Ruth Knuechel, Josef Rueschoff, Ferdinand Hofstaedter, and Richard Fishel

Frequent Microsatellite Instability in Sporadic Tumors of the Upper Urinary Tract
Cancer Res 2002 62: 6796-6802. [Abstract] [Full Text] [PDF]  

Anat Bar-Shira, Jehonathan H. Pinthus, Uri Rozovsky, Myriam Goldstein, William R. Sellers, Yuval Yaron, Zelig Eshhar, and Avi Orr-Urtreger

Multiple Genes in Human 20q13 Chromosomal Region Are Involved in an Advanced Prostate Cancer Xenograft
Cancer Res 2002 62: 6803-6807. [Abstract] [Full Text] [PDF]  

Oddbjørn Straume, Pierre O. Chappuis, Helga B. Salvesen, Ole J. Halvorsen, Svein A. Haukaas, John R. Goffin, Louis R. Bégin, William D. Foulkes, and Lars A. Akslen

Prognostic Importance of Glomeruloid Microvascular Proliferation Indicates an Aggressive Angiogenic Phenotype in Human Cancers
Cancer Res 2002 62: 6808-6811. [Abstract] [Full Text] [PDF]  

Vasantha Srikantan, Michael Valladares, Johng S. Rhim, Judd W. Moul, and Shiv Srivastava

HEPSIN Inhibits Cell Growth/Invasion in Prostate Cancer Cells
Cancer Res 2002 62: 6812-6816. [Abstract] [Full Text] [PDF]  

Joseph T. O’Flaherty, LeAnn C. Rogers, Brad A. Chadwell, John S. Owen, Anurada Rao, Scott D. Cramer, and Larry W. Daniel

5(S)-Hydroxy-6,8,11,14-E,Z,Z,Z-eicosatetraenoate Stimulates PC3 Cell Signaling and Growth by a Receptor-dependent Mechanism
Cancer Res 2002 62: 6817-6819. [Abstract] [Full Text] [PDF]  

Fumiaki Sato, David Shibata, Noam Harpaz, Yan Xu, Jing Yin, Yuriko Mori, Suna Wang, Andreea Olaru, Elena Deacu, Florin M. Selaru, Martha C. Kimos, Prodromos Hytiroglou, Joanne Young, Barbara Leggett, Adi F. Gazdar, Shinichi Toyooka, John M. Abraham, and Stephen J. Meltzer

Aberrant Methylation of the HPP1 Gene in Ulcerative Colitis-associated Colorectal Carcinoma
Cancer Res 2002 62: 6820-6822. [Abstract] [Full Text] [PDF]  

Wa’el El-Rifai, Christopher A. Moskaluk, Mohammad Khalouck Abdrabbo, Jeffery Harper, Cynthia Yoshida, Gregory J. Riggins, Henry F. Frierson, Jr., and Steven M. Powell

Gastric Cancers Overexpress S100A Calcium-binding Proteins
Cancer Res 2002 62: 6823-6826. [Abstract] [Full Text] [PDF]  

Kevin L. Bennewith, James A. Raleigh, and Ralph E. Durand

Orally Administered Pimonidazole to Label Hypoxic Tumor Cells
Cancer Res 2002 62: 6827-6830. [Abstract] [Full Text] [PDF]  

Robert B. Campbell, Dai Fukumura, Edward B. Brown, Laureen M. Mazzola, Yotaro Izumi, Rakesh K. Jain, Vladimir P. Torchilin, and Lance L. Munn

Cationic Charge Determines the Distribution of Liposomes between the Vascular and Extravascular Compartments of Tumors
Cancer Res 2002 62: 6831-6836. [Abstract] [Full Text] [PDF]  

Biochemistry and Biophysics:

Hua-Bei Guo, Intaek Lee, Maria Kamar, Steven K. Akiyama, and Michael Pierce

Aberrant N-Glycosylation of ß₁ Integrin Causes Reduced ₅ß₁ Integrin Clustering and Stimulates Cell Migration
Cancer Res 2002 62: 6837-6845. [Abstract] [Full Text] [PDF]  

Carcinogenesis:

Masahiro Sonoshita, Kazuaki Takaku, Masanobu Oshima, Ken-ichi Sugihara, and Makoto M. Taketo

Cyclooxygenase-2 Expression in Fibroblasts and Endothelial Cells of Intestinal Polyps
Cancer Res 2002 62: 6846-6849. [Abstract] [Full Text] [PDF]  

Lori R. Kisley, Bradley S. Barrett, Alison K. Bauer, Lori D. Dwyer-Nield, Benjamin Barthel, Amy M. Meyer, David C. Thompson, and Alvin M. Malkinson

Genetic Ablation of Inducible Nitric Oxide Synthase Decreases Mouse Lung Tumorigenesis
Cancer Res 2002 62: 6850-6856. [Abstract] [Full Text] [PDF]  

Epidemiology and Prevention:

Chuanshu Huang, Yi Huang, Jingxia Li, Wenwei Hu, Robeena Aziz, Moon-shong Tang, Nanjun Sun, John Cassady, and Gary D. Stoner

Inhibition of Benzo(a)pyrene Diol-Epoxide-induced Transactivation of Activated Protein 1 and Nuclear Factor B by Black Raspberry Extracts
Cancer Res 2002 62: 6857-6863. [Abstract] [Full Text] [PDF]  

Experimental Therapeutics:

Elizabeth Alli, Judy Bash-Babula, Jin-Ming Yang, and William N. Hait

Effect of Stathmin on the Sensitivity to Antimicrotubule Drugs in Human Breast Cancer
Cancer Res 2002 62: 6864-6869. [Abstract] [Full Text] [PDF]  

Courtney L. Scaife, Jinqiu Kuang, Jason C. Wills, D. Brad Trowbridge, Phil Gray, Bernadette M. Manning, Ernst J. Eichwald, Raymond A. Daynes, and Scott K. Kuwada

Nuclear Factor B Inhibitors Induce Adhesion-dependent Colon Cancer Apoptosis: Implications for Metastasis
Cancer Res 2002 62: 6870-6878. [Abstract] [Full Text] [PDF]  

Irina Trofimova, Alexandre Dimtchev, Mira Jung, Dean Rosenthal, Mark Smulson, Anatoly Dritschilo, and Viatcheslav Soldatenkov

Gene Therapy for Prostate Cancer by Targeting Poly(ADP-Ribose) Polymerase
Cancer Res 2002 62: 6879-6883. [Abstract] [Full Text] [PDF]  

Martin Hagedorn, Lior Zilberberg, Jörg Wilting, Xavier Canron, Giorgio Carrabba, Carlo Giussani, Mauro Pluderi, Lorenzo Bello, and Andreas Bikfalvi

Domain Swapping in a COOH-terminal Fragment of Platelet Factor 4 Generates Potent Angiogenesis Inhibitors
Cancer Res 2002 62: 6884-6890. [Abstract] [Full Text] [PDF]  

Shane K. Green, Mikael C. I. Karlsson, Jeffrey V. Ravetch, and Robert S. Kerbel

Disruption of Cell-Cell Adhesion Enhances Antibody-dependent Cellular Cytotoxicity: Implications for Antibody-based Therapeutics of Cancer
Cancer Res 2002 62: 6891-6900. [Abstract] [Full Text] [PDF]  

Simone Gaedicke, Elke Firat-Geier, Oana Constantiniu, Maria Lucchiari-Hartz, Marina Freudenberg, Chris Galanos, and Gabriele Niedermann

Antitumor Effect of the Human Immunodeficiency Virus Protease Inhibitor Ritonavir: Induction of Tumor-Cell Apoptosis Associated with Perturbation of Proteasomal Proteolysis
Cancer Res 2002 62: 6901-6908. [Abstract] [Full Text] [PDF]  

Naoto Takahashi, WeiWei Li, Debabrata Banerjee, Yongbiao Guan, Yasuko Wada-Takahashi, Murray F. Brennan, Ting-Chao Chou, Kathleen W. Scotto, and Joseph R. Bertino

Sequence-dependent Synergistic Cytotoxicity of Ecteinascidin-743 and Paclitaxel in Human Breast Cancer Cell Lines in Vitro and in Vivo
Cancer Res 2002 62: 6909-6915. [Abstract] [Full Text] [PDF]  

Rina Hui, Georgina L. Finney, Jason S. Carroll, Christine S. L. Lee, Elizabeth A. Musgrove, and Robert L. Sutherland

Constitutive Overexpression of Cyclin D1 but not Cyclin E Confers Acute Resistance to Antiestrogens in T-47D Breast Cancer Cells
Cancer Res 2002 62: 6916-6923. [Abstract] [Full Text] [PDF]  

Tsung Wen Chong, Lawrence D. Horwitz, John W. Moore, Heidi M. Sowter, and Adrian L. Harris

A Mycobacterial Iron Chelator, Desferri-Exochelin, Induces Hypoxia-inducible Factors 1 and 2, NIP3, and Vascular Endothelial Growth Factor in Cancer Cell Lines
Cancer Res 2002 62: 6924-6927. [Abstract] [Full Text] [PDF]  

Pamela S. Schwartz, Chong-Sheng Chen, and David J. Waxman

Enhanced Bystander Cytotoxicity of P450 Gene-directed Enzyme Prodrug Therapy by Expression of the Antiapoptotic Factor p35
Cancer Res 2002 62: 6928-6937. [Abstract] [Full Text] [PDF]  

Guido Bocci, K. C. Nicolaou, and Robert S. Kerbel

Protracted Low-Dose Effects on Human Endothelial Cell Proliferation and Survival in Vitro Reveal a Selective Antiangiogenic Window for Various Chemotherapeutic Drugs
Cancer Res 2002 62: 6938-6943. [Abstract] [Full Text] [PDF]  

Immunology:

John W. Greiner, Hasan Zeytin, Miriam R. Anver, and Jeffrey Schlom

Vaccine-based Therapy Directed against Carcinoembryonic Antigen Demonstrates Antitumor Activity on Spontaneous Intestinal Tumors in the Absence of Autoimmunity
Cancer Res 2002 62: 6944-6951. [Abstract] [Full Text] [PDF]  

Chen-Lung Lin, Wei-Feng Lo, Tzong-Hsien Lee, Yi Ren, Shiuh-Lin Hwang, Yu-Fan Cheng, Chao-Long Chen, Yu-Sen Chang, Steve P. Lee, Alan B. Rickinson, and Paul Kwong Hang Tam

Immunization with Epstein-Barr Virus (EBV) Peptide-pulsed Dendritic Cells Induces Functional CD8+ T-Cell Immunity and May Lead to Tumor Regression in Patients with EBV-positive Nasopharyngeal Carcinoma
Cancer Res 2002 62: 6952-6958. [Abstract] [Full Text] [PDF]  

Molecular Biology and Genetics:

William Alazawi, Mark Pett, Barbara Arch, Laurie Scott, Tom Freeman, Margaret A. Stanley, and Nicholas Coleman

Changes in Cervical Keratinocyte Gene Expression Associated with Integration of Human Papillomavirus 16
Cancer Res 2002 62: 6959-6965. [Abstract] [Full Text] [PDF]  

Joseph S. Palumbo, Jill M. Potter, Lisa S. Kaplan, Kathryn Talmage, David G. Jackson, and Jay L. Degen

Spontaneous Hematogenous and Lymphatic Metastasis, but not Primary Tumor Growth or Angiogenesis, Is Diminished in Fibrinogen-deficient Mice
Cancer Res 2002 62: 6966-6972. [Abstract] [Full Text] [PDF]  

Marta Sanchez-Carbayo, Nicholas D. Socci, Elizabeth Charytonowicz, Minglan Lu, Michael Prystowsky, Geoffrey Childs, and Carlos Cordon-Cardo

Molecular Profiling of Bladder Cancer Using cDNA Microarrays: Defining Histogenesis and Biological Phenotypes
Cancer Res 2002 62: 6973-6980. [Abstract] [Full Text] [PDF]  

Michael A. Harding, Karen C. Arden, James W. Gildea, John J. Gildea, Elizabeth J. Perlman, Carrie Viars, and Dan Theodorescu

Functional Genomic Comparison of Lineage-related Human Bladder Cancer Cell Lines with Differing Tumorigenic and Metastatic Potentials by Spectral Karyotyping, Comparative Genomic Hybridization, and a Novel Method of Positional Expression Profiling
Cancer Res 2002 62: 6981-6989. [Abstract] [Full Text] [PDF]  

Wei-Min Tong, Ulrich Cortes, M. Prakash Hande, Hiroko Ohgaki, Luciane R. Cavalli, Peter M. Lansdorp, Bassem R. Haddad, and Zhao-Qi Wang

Synergistic Role of Ku80 and Poly(ADP-ribose) Polymerase in Suppressing Chromosomal Aberrations and Liver Cancer Formation
Cancer Res 2002 62: 6990-6996. [Abstract] [Full Text] [PDF]  

Marcia S. Brose, Patricia Volpe, Michael Feldman, Madhu Kumar, Irum Rishi, Renee Gerrero, Eugene Einhorn, Meenhard Herlyn, John Minna, Andrew Nicholson, Jack A. Roth, Steven M. Albelda, Helen Davies, Charles Cox, Graham Brignell, Philip Stephens, P. Andrew Futreal, Richard Wooster, Michael R. Stratton, and Barbara L. Weber

BRAF and RAS Mutations in Human Lung Cancer and Melanoma
Cancer Res 2002 62: 6997-7000. [Abstract] [Full Text] [PDF]  

Katsuhiko Naoki, Tzu-Hsiu Chen, William G. Richards, David J. Sugarbaker, and Matthew Meyerson

Missense Mutations of the BRAF Gene in Human Lung Adenocarcinoma
Cancer Res 2002 62: 7001-7003. [Abstract] [Full Text] [PDF]  

Hidetoshi Murata, Nobuyoshi Tajima, Yoji Nagashima, Masahiro Yao, Masaya Baba, Masayuki Goto, Susumu Kawamoto, Isao Yamamoto, Kenji Okuda, and Hiroshi Kanno

Von Hippel-Lindau Tumor Suppressor Protein Transforms Human Neuroblastoma Cells into Functional Neuron-like Cells
Cancer Res 2002 62: 7004-7011. [Abstract] [Full Text] [PDF]  

Suguru Hasegawa, Yoichi Furukawa, Meihua Li, Seiji Satoh, Tatsushi Kato, Takeshi Watanabe, Toyomasa Katagiri, Tatsuhiko Tsunoda, Yoshio Yamaoka, and Yusuke Nakamura

Genome-Wide Analysis of Gene Expression in Intestinal-Type Gastric Cancers Using a Complementary DNA Microarray Representing 23,040 Genes
Cancer Res 2002 62: 7012-7017. [Abstract] [Full Text] [PDF]  

Stefan Heckl, Jürgen Debus, Jürgen Jenne, Rüdiger Pipkorn, Waldemar Waldeck, Herbert Spring, Ralf Rastert, Claus W. von der Lieth, and Klaus Braun

CNN-Gd³⁺ Enables Cell Nucleus Molecular Imaging of Prostate Cancer Cells: The Last 600 nm
Cancer Res 2002 62: 7018-7024. [Abstract] [Full Text] [PDF]  

Annalisa Lorenzato, Martina Olivero, Salvatore Patanè, Edoardo Rosso, Alberto Oliaro, Paolo M. Comoglio, and Maria Flavia Di Renzo

Novel Somatic Mutations of the MET Oncogene in Human Carcinoma Metastases Activating Cell Motility and Invasion
Cancer Res 2002 62: 7025-7030. [Abstract] [Full Text] [PDF]  

Tatiana I. Rogounovitch, Vladimir A. Saenko, Yuki Shimizu-Yoshida, Aleksandr Yu. Abrosimov, Eugeny F. Lushnikov, Pavel O. Roumiantsev, Akira Ohtsuru, Hiroyuki Namba, Anatoly F. Tsyb, and Shunichi Yamashita

Large Deletions in Mitochondrial DNA in Radiation-associated Human Thyroid Tumors
Cancer Res 2002 62: 7031-7041. [Abstract] [Full Text] [PDF]  

Tumor Biology:

Emilio Barbera-Guillem, Julie K. Nyhus, Chris C. Wolford, Chad R. Friece, and James W. Sampsel

Vascular Endothelial Growth Factor Secretion by Tumor-infiltrating Macrophages Essentially Supports Tumor Angiogenesis, and IgG Immune Complexes Potentiate the Process
Cancer Res 2002 62: 7042-7049. [Abstract] [Full Text] [PDF]  

Elena Puccetti, Darja Obradovic, Tim Beissert, Andrea Bianchini, Birgit Washburn, Ferdinando Chiaradonna, Simone Boehrer, Dieter Hoelzer, Oliver Gerhard Ottmann, Pier Giuseppe Pelicci, Clara Nervi, and Martin Ruthardt

AML-associated Translocation Products Block Vitamin D₃-induced Differentiation by Sequestering the Vitamin D₃ Receptor
Cancer Res 2002 62: 7050-7058. [Abstract] [Full Text] [PDF]  

Ruud Clarijs, Lia Schalkwijk, Uta B. Hofmann, Dirk J. Ruiter, and Robert M. W. de Waal

Induction of Vascular Endothelial Growth Factor Receptor-3 Expression on Tumor Microvasculature as a New Progression Marker in Human Cutaneous Melanoma
Cancer Res 2002 62: 7059-7065. [Abstract] [Full Text] [PDF]  

Johannes H. A. M. Kaanders, Karien I. E. M. Wijffels, Henri A. M. Marres, Anna S. E. Ljungkvist, Lucas A. M. Pop, Franciscus J. A. van den Hoogen, Peter C. M. de Wilde, Johan Bussink, James A. Raleigh, and Albert J. van der Kogel

Pimonidazole Binding and Tumor Vascularity Predict for Treatment Outcome in Head and Neck Cancer
Cancer Res 2002 62: 7066-7074. [Abstract] [Full Text] [PDF]  

Stefan Duensing and Karl Münger

The Human Papillomavirus Type 16 E6 and E7 Oncoproteins Independently Induce Numerical and Structural Chromosome Instability
Cancer Res 2002 62: 7075-7082. [Abstract] [Full Text] [PDF]  

Andries Zijlstra, Rebecca Mellor, Giano Panzarella, Ronald T. Aimes, John D. Hooper, Natalia D. Marchenko, and James P. Quigley

A Quantitative Analysis of Rate-limiting Steps in the Metastatic Cascade Using Human-specific Real-Time Polymerase Chain Reaction
Cancer Res 2002 62: 7083-7092. [Abstract] [Full Text] [PDF]  

Sahnila Enam, Luis Del Valle, César Lara, Dai-Di Gan, Carlos Ortiz-Hidalgo, Juan P. Palazzo, and Kamel Khalili

Association of Human Polyomavirus JCV with Colon Cancer: Evidence for Interaction of Viral T-Antigen and ß-Catenin
Cancer Res 2002 62: 7093-7101. [Abstract] [Full Text] [PDF]  

John Muschler, Dinah Levy, Roseanne Boudreau, Michael Henry, Kevin Campbell, and Mina J. Bissell

A Role for Dystroglycan in Epithelial Polarization: Loss of Function in Breast Tumor Cells
Cancer Res 2002 62: 7102-7109. [Abstract] [Full Text] [PDF]  

Lodewyk F. A. Wessels, Tibor van Welsem, Augustinus A. M. Hart, Laura J. van’t Veer, Marcel J. T. Reinders, and Petra M. Nederlof

Molecular Classification of Breast Carcinomas by Comparative Genomic Hybridization: a Specific Somatic Genetic Profile for BRCA1 Tumors
Cancer Res 2002 62: 7110-7117. [Abstract] [Full Text] [PDF]  

Amr El-Sheikh, Cheng Liu, Haining Huang, and Thomas S. Edgington

A Novel Vascular Endothelial Growth Factor Heparin-binding Domain Substructure Binds to Glycosaminoglycans in Vivo and Localizes to Tumor Microvascular Endothelium
Cancer Res 2002 62: 7118-7123. [Abstract] [Full Text] [PDF]  

Fumihiro Tanaka, Shinya Ishikawa, Kazuhiro Yanagihara, Ryo Miyahara, Yozo Kawano, Mio Li, Yosuke Otake, and Hiromi Wada

Expression of Angiopoietins and Its Clinical Significance in Non-Small Cell Lung Cancer
Cancer Res 2002 62: 7124-7129. [Abstract] [Full Text] [PDF]  

Errata:

Cancer Res 2002 62: 7132. [Full Text] [PDF]  

Correction:

Cancer Res 2002 62: 7133. [Full Text] [PDF]  

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