Advances in Brief:

Ali H. Shah, William B. Tabayoyong, Shilajit D. Kundu, Seong-Jin Kim, Luk Van Parijs, Victoria C. Liu, Eugene Kwon, Norman M. Greenberg, and Chung Lee

Suppression of Tumor Metastasis by Blockade of Transforming Growth Factor ß Signaling in Bone Marrow Cells through a Retroviral-mediated Gene Therapy in Mice
Cancer Res 2002 62: 7135-7138. [Abstract] [Full Text] [PDF]  

Jesper Nylandsted, Wolfgang Wick, Ulrich A. Hirt, Karsten Brand, Mikkel Rohde, Marcel Leist, Michael Weller, and Marja Jäättelä

Eradication of Glioblastoma, and Breast and Colon Carcinoma Xenografts by Hsp70 Depletion
Cancer Res 2002 62: 7139-7142. [Abstract] [Full Text] [PDF]  

Edith I. Cline, Silvio Bicciato, Carlo DiBello, and Mark W. Lingen

Prediction of in Vivo Synergistic Activity of Antiangiogenic Compounds by Gene Expression Profiling
Cancer Res 2002 62: 7143-7148. [Abstract] [Full Text] [PDF]  

Paul La Rosée, Amie S. Corbin, Eric P. Stoffregen, Michael W. Deininger, and Brian J. Druker

Activity of the Bcr-Abl Kinase Inhibitor PD180970 against Clinically Relevant Bcr-Abl Isoforms That Cause Resistance to Imatinib Mesylate (Gleevec, STI571)
Cancer Res 2002 62: 7149-7153. [Abstract] [Full Text] [PDF]  

Michael Hoa, Shannon L. Davis, Sarah J. Ames, and Remco A. Spanjaard

Amplification of Wild-Type K-ras Promotes Growth of Head and Neck Squamous Cell Carcinoma
Cancer Res 2002 62: 7154-7156. [Abstract] [Full Text] [PDF]  

Terence C-M. Tang, Jonathan S. T. Sham, Dan Xie, Yan Fang, Ke-Ke Huo, Qiu-Liang Wu, and Xin-Yuan Guan

Identification of a Candidate Oncogene SEI-1 within a Minimal Amplified Region at 19q13.1 in Ovarian Cancer Cell Lines
Cancer Res 2002 62: 7157-7161. [Abstract] [Full Text] [PDF]  

Minoru Fukuchi, Yasuyuki Fukai, Norihiro Masuda, Tatsuya Miyazaki, Masanobu Nakajima, Makoto Sohda, Ryokuhei Manda, Katsuhiko Tsukada, Hiroyuki Kato, and Hiroyuki Kuwano

High-Level Expression of the Smad Ubiquitin Ligase Smurf2 Correlates with Poor Prognosis in Patients with Esophageal Squamous Cell Carcinoma
Cancer Res 2002 62: 7162-7165. [Abstract] [Full Text] [PDF] Supplementary Data  

Fayyaz Ahmed, Jeffrey Wyckoff, Elaine Y. Lin, Weigang Wang, Yarong Wang, Lothar Hennighausen, Jun-ichi Miyazaki, Joan Jones, Jeffrey W. Pollard, John S. Condeelis, and Jeffrey E. Segall

GFP Expression in the Mammary Gland for Imaging of Mammary Tumor Cells in Transgenic Mice
Cancer Res 2002 62: 7166-7169. [Abstract] [Full Text] [PDF]  

Moneeb Ehtesham, Peter Kabos, Mervin A. R. Gutierrez, Nancy H. C. Chung, Thomas S. Griffith, Keith L. Black, and John S. Yu

Induction of Glioblastoma Apoptosis Using Neural Stem Cell-mediated Delivery of Tumor Necrosis Factor-related Apoptosis-inducing Ligand
Cancer Res 2002 62: 7170-7174. [Abstract] [Full Text] [PDF]  

Julia Beatty, Anne Terry, Julie MacDonald, Elizabeth Gault, Stan Cevario, Stephen J. O’Brien, Ewan Cameron, and James C. Neil

Feline Immunodeficiency Virus Integration in B-Cell Lymphoma Identifies a Candidate Tumor Suppressor Gene on Human Chromosome 15q15
Cancer Res 2002 62: 7175-7180. [Abstract] [Full Text] [PDF]  

Sandy Wotton, Monica Stewart, Karen Blyth, Francois Vaillant, Anna Kilbey, James C. Neil, and Ewan R. Cameron

Proviral Insertion Indicates a Dominant Oncogenic Role for Runx1/AML-1 in T-Cell Lymphoma
Cancer Res 2002 62: 7181-7185. [Abstract] [Full Text] [PDF]  

Sophie Couvé-Privat, Bakar Bouadjar, Marie Françoise Avril, Alain Sarasin, and Leela Daya-Grosjean

Significantly High Levels of Ultraviolet-specific Mutations in the Smoothened Gene in Basal Cell Carcinomas from DNA Repair-deficient Xeroderma Pigmentosum Patients
Cancer Res 2002 62: 7186-7189. [Abstract] [Full Text] [PDF]  

Puja Sapra and Theresa M. Allen

Internalizing Antibodies Are Necessary for Improved Therapeutic Efficacy of Antibody-targeted Liposomal Drugs
Cancer Res 2002 62: 7190-7194. [Abstract] [Full Text] [PDF]  

Kui Shin Voo, Tihui Fu, Helen E. Heslop, Malcolm K. Brenner, Cliona M. Rooney, and Rong-Fu Wang

Identification of HLA-DP3-restricted Peptides from EBNA1 Recognized by CD4⁺ T Cells
Cancer Res 2002 62: 7195-7199. [Abstract] [Full Text] [PDF]  

Colby A. Wyatt, Charles I. Coon, Jennifer J. Gibson, and Constance E. Brinckerhoff

Potential for the 2G Single Nucleotide Polymorphism in the Promoter of Matrix Metalloproteinase to Enhance Gene Expression in Normal Stromal Cells
Cancer Res 2002 62: 7200-7202. [Abstract] [Full Text] [PDF]  

Robin E. Bachelder, Melissa A. Wendt, and Arthur M. Mercurio

Vascular Endothelial Growth Factor Promotes Breast Carcinoma Invasion in an Autocrine Manner by Regulating the Chemokine Receptor CXCR4
Cancer Res 2002 62: 7203-7206. [Abstract] [Full Text] [PDF]  

Ramachandra K. Reddy, Louis Dubeau, Heather Kleiner, Tyler Parr, Peter Nichols, Bryce Ko, Dezheng Dong, Howard Ko, Changhui Mao, John DiGiovanni, and Amy S. Lee

Cancer-inducible Transgene Expression by the Grp94 Promoter: Spontaneous Activation in Tumors of Various Origins and Cancer-associated Macrophages
Cancer Res 2002 62: 7207-7212. [Abstract] [Full Text] [PDF]  

Jill A. Fahrner, Sayaka Eguchi, James G. Herman, and Stephen B. Baylin

Dependence of Histone Modifications and Gene Expression on DNA Hypermethylation in Cancer
Cancer Res 2002 62: 7213-7218. [Abstract] [Full Text] [PDF]  

Biochemistry and Biophysics:

Amélie Lansiaux, Farial Tanious, Zohar Mishal, Laurent Dassonneville, Arvind Kumar, Chad E. Stephens, Qiyue Hu, W. David Wilson, David W. Boykin, and Christian Bailly

Distribution of Furamidine Analogues in Tumor Cells: Targeting of the Nucleus or Mitochondria Depending on the Amidine Substitution
Cancer Res 2002 62: 7219-7229. [Abstract] [Full Text] [PDF]  

Carcinogenesis:

Antony R. Parker, Robert N. O’Meally, Dwight H. Oliver, Li Hua, William G. Nelson, Theodore L. DeWeese, and James R. Eshleman

8-Hydroxyguanosine Repair Is Defective in Some Microsatellite Stable Colorectal Cancer Cells
Cancer Res 2002 62: 7230-7233. [Abstract] [Full Text] [PDF]  

Tae-Yoon Kim, Han-Jeong Myoung, Ji-Hyun Kim, In-Sung Moon, Tai-Gyu Kim, Woong-Shick Ahn, and Jeong-Im Sin

Both E7 and CpG-Oligodeoxynucleotide Are Required for Protective Immunity against Challenge with Human Papillomavirus 16 (E6/E7) Immortalized Tumor Cells: Involvement of CD4+ and CD8+ T Cells in Protection
Cancer Res 2002 62: 7234-7240. [Abstract] [Full Text] [PDF]  

Epidemiology and Prevention:

Jungil Hong, Hong Lu, Xiaofeng Meng, Jae-Ha Ryu, Yukihiko Hara, and Chung S. Yang

Stability, Cellular Uptake, Biotransformation, and Efflux of Tea Polyphenol (-)-Epigallocatechin-3-Gallate in HT-29 Human Colon Adenocarcinoma Cells
Cancer Res 2002 62: 7241-7246. [Abstract] [Full Text] [PDF]  

Experimental Therapeutics:

Peter D. Davis, Graeme J. Dougherty, David C. Blakey, Susan M. Galbraith, Gillian M. Tozer, Angela L. Holder, Matthew A. Naylor, John Nolan, Michael R. L. Stratford, David J. Chaplin, and Sally A. Hill

ZD6126: A Novel Vascular-targeting Agent That Causes Selective Destruction of Tumor Vasculature
Cancer Res 2002 62: 7247-7253. [Abstract] [Full Text] [PDF]  

Hank C. Hill, Thomas F. Conway, Jr., Michael S. Sabel, Yong S. Jong, Edith Mathiowitz, Richard B. Bankert, and Nejat K. Egilmez

Cancer Immunotherapy with Interleukin 12 and Granulocyte-Macrophage Colony-stimulating Factor-encapsulated Microspheres: Coinduction of Innate and Adaptive Antitumor Immunity and Cure of Disseminated Disease
Cancer Res 2002 62: 7254-7263. [Abstract] [Full Text] [PDF]  

Jia-Ju Bao, Xiao-Feng Le, Rui-Yu Wang, Jiuhong Yuan, Lin Wang, Edward N. Atkinson, Ruth LaPushin, Michael Andreeff, Bingliang Fang, Yinhua Yu, and Robert C. Bast, Jr.

Reexpression of the Tumor Suppressor Gene ARHI Induces Apoptosis in Ovarian and Breast Cancer Cells through a Caspase-independent Calpain-dependent Pathway
Cancer Res 2002 62: 7264-7272. [Abstract] [Full Text] [PDF]  

Theresa M. Busch, E. Paul Wileyto, Micheal J. Emanuele, Fabio Del Piero, Laura Marconato, Eli Glatstein, and Cameron J. Koch

Photodynamic Therapy Creates Fluence Rate-dependent Gradients in the Intratumoral Spatial Distribution of Oxygen
Cancer Res 2002 62: 7273-7279. [Abstract] [Full Text] [PDF]  

Jared L. Nelson, Beverly L. Roeder, John C. Carmen, Friederike Roloff, and William G. Pitt

Ultrasonically Activated Chemotherapeutic Drug Delivery in a Rat Model
Cancer Res 2002 62: 7280-7283. [Abstract] [Full Text] [PDF]  

Francesca Carlomagno, Donata Vitagliano, Teresa Guida, Fortunato Ciardiello, Giampaolo Tortora, Giancarlo Vecchio, Anderson J. Ryan, Gabriella Fontanini, Alfredo Fusco, and Massimo Santoro

ZD6474, an Orally Available Inhibitor of KDR Tyrosine Kinase Activity, Efficiently Blocks Oncogenic RET Kinases
Cancer Res 2002 62: 7284-7290. [Abstract] [Full Text] [PDF]  

Jeffrey S. Eshleman, Brett L. Carlson, Ann C. Mladek, Brian D. Kastner, Kathleen L. Shide, and Jann N. Sarkaria

Inhibition of the Mammalian Target of Rapamycin Sensitizes U87 Xenografts to Fractionated Radiation Therapy
Cancer Res 2002 62: 7291-7297. [Abstract] [Full Text] [PDF]  

Marieke H. Mossink, Arend van Zon, Erna Fränzel-Luiten, Martijn Schoester, Valerie A. Kickhoefer, George L. Scheffer, Rik J. Scheper, Pieter Sonneveld, and Erik A. C. Wiemer

Disruption of the Murine Major Vault Protein (MVP/LRP) Gene Does Not Induce Hypersensitivity to Cytostatics
Cancer Res 2002 62: 7298-7304. [Abstract] [Full Text] [PDF]  

Molecular Biology and Genetics:

Jeffrey Hildesheim, Dmitry V. Bulavin, Miriam R. Anver, W. Gregory Alvord, M. Christine Hollander, Lilit Vardanian, and Albert J. Fornace, Jr.

Gadd45a Protects against UV Irradiation-induced Skin Tumors, and Promotes Apoptosis and Stress Signaling via MAPK and p53
Cancer Res 2002 62: 7305-7315. [Abstract] [Full Text] [PDF] Supplementary Data  

Peiwen Fei, Eric J. Bernhard, and Wafik S. El-Deiry

Tissue-specific Induction of p53 Targets in Vivo
Cancer Res 2002 62: 7316-7327. [Abstract] [Full Text] [PDF]  

Tumor Biology:

Takashi Murakami, Wusi Maki, Adela R. Cardones, Hui Fang, Adrian Tun Kyi, Frank O. Nestle, and Sam T. Hwang

Expression of CXC Chemokine Receptor-4 Enhances the Pulmonary Metastatic Potential of Murine B16 Melanoma Cells
Cancer Res 2002 62: 7328-7334. [Abstract] [Full Text] [PDF]  

Punita Dhawan, Amar B. Singh, Darrel L. Ellis, and Ann Richmond

Constitutive Activation of Akt/Protein Kinase B in Melanoma Leads to Up-Regulation of Nuclear Factor-B and Tumor Progression
Cancer Res 2002 62: 7335-7342. [Abstract] [Full Text] [PDF]  

Mary Ann C. Sabino, Joseph R. Ghilardi, Joost L. M. Jongen, Cathy P. Keyser, Nancy M. Luger, David B. Mach, Christopher M. Peters, Scott D. Rogers, Matthew J. Schwei, Carmen de Felipe, and Patrick W. Mantyh

Simultaneous Reduction in Cancer Pain, Bone Destruction, and Tumor Growth by Selective Inhibition of Cyclooxygenase-2
Cancer Res 2002 62: 7343-7349. [Abstract] [Full Text] [PDF]  

K. Kian Ang, Brian A. Berkey, Xiaoyu Tu, Hua-Zhong Zhang, Ruth Katz, Elizabeth H. Hammond, Karen K. Fu, and Luka Milas

Impact of Epidermal Growth Factor Receptor Expression on Survival and Pattern of Relapse in Patients with Advanced Head and Neck Carcinoma
Cancer Res 2002 62: 7350-7356. [Abstract] [Full Text] [PDF]  

Alexandre Chlenski, Shuqing Liu, Susan E. Crawford, Olga V. Volpert, George H. DeVries, Amy Evangelista, Qiwei Yang, Helen R. Salwen, Robert Farrer, James Bray, and Susan L. Cohn

SPARC Is a Key Schwannian-derived Inhibitor Controlling Neuroblastoma Tumor Angiogenesis
Cancer Res 2002 62: 7357-7363. [Abstract] [Full Text] [PDF]  

Riku Koivusalo, Eberhard Krausz, Pertti Ruotsalainen, Hans Helenius, and Sakari Hietanen

Chemoradiation of Cervical Cancer Cells: Targeting Human Papillomavirus E6 and p53 Leads to Either Augmented or Attenuated Apoptosis Depending on the Platinum Carrier Ligand
Cancer Res 2002 62: 7364-7371. [Abstract] [Full Text] [PDF]  

Randy J. Levitt and Michael Pollak

Insulin-like Growth Factor-I Antagonizes the Antiproliferative Effects of Cyclooxygenase-2 Inhibitors on BxPC-3 Pancreatic Cancer Cells
Cancer Res 2002 62: 7372-7376. [Abstract] [Full Text] [PDF]  

Obituary:

Mansukh C. Wani

In Memoriam: Monroe E. Wall (1916–2002)
Cancer Res 2002 62: 7377. [Full Text] [PDF]  

Erratum:

Cancer Res 2002 62: 7379. [Full Text] [PDF]  

Corrections:

Cancer Res 2002 62: 7380. [Full Text] [PDF]  

Cancer Res 2002 62: 7380. [Full Text] [PDF]  

Cancer Res 2002 62: 7380. [Full Text] [PDF]  

Acknowledgment to Reviewers:

Acknowledgment to Reviewers
Cancer Res 2002 62: 7381-7391. [Full Text] [PDF]  

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