Advances in Brief:

Array-based Comparative Genomic Hybridization for the Differential Diagnosis of Renal Cell Cancer

Mónica Wilhelm, Joris A. Veltman, Adam B. Olshen, Ajay N. Jain, Dan H. Moore, Joe C. Presti, Jr., Gyula Kovacs, and Frederic M. Waldman
Cancer Res 2002 62: 957-960. [Abstract] [Full Text] [PDF]  

Analysis of Gene Induction in Human Fibroblasts and Bladder Cancer Cells Exposed to the Methylation Inhibitor 5-Aza-2'-deoxycytidine

Gangning Liang, Felicidad A. Gonzales, Peter A. Jones, Torben F. Orntoft, and Thomas Thykjaer
Cancer Res 2002 62: 961-966. [Abstract] [Full Text] [PDF]  

Genomic Amplification in Retinoblastoma Narrowed to 0.6 Megabase on Chromosome 6p Containing a Kinesin-like Gene, RBKIN

Danian Chen, Sanja Pajovic, Allison Duckett, Vivette D. Brown, Jeremy A. Squire, and Brenda L. Gallie
Cancer Res 2002 62: 967-971. [Abstract] [Full Text] [PDF]  

Comprehensive Scanning of Somatic Mitochondrial DNA Mutations in Breast Cancer

Duan-Jun Tan, Ren-Kui Bai, and Lee-Jun C. Wong
Cancer Res 2002 62: 972-976. [Abstract] [Full Text] [PDF]  

Enhanced Phagemid Particle Gene Transfer in Camptothecin-treated Carcinoma Cells

Michael A. Burg, Kristen Jensen-Pergakes, Ana Maria Gonzalez, Prenn Ravey, Andrew Baird, and David Larocca
Cancer Res 2002 62: 977-981. [Abstract] [Full Text] [PDF]  

The Role of Ral A in Epidermal Growth Factor Receptor-regulated Cell Motility

John J. Gildea, Michael A. Harding, M. Jabed Seraj, Kay M. Gulding, and Dan Theodorescu
Cancer Res 2002 62: 982-985. [Abstract] [Full Text] [PDF]  

Trk Receptor Inhibition Induces Apoptosis of Proliferating but not Quiescent Human Osteoblasts

Jacek Pinski, Ashani Weeraratna, Aarti R. Uzgare, Julia T. Arnold, Samuel R. Denmeade, and John T. Isaacs
Cancer Res 2002 62: 986-989. [Abstract] [Full Text] [PDF]  

Cancer Susceptibility of Mice with a Homozygous Deletion in the COOH-Terminal Domain of the Brca2 Gene

Kimberly A. McAllister, L. Michelle Bennett, Chris D. Houle, Toni Ward, Jason Malphurs, N. Keith Collins, Carol Cachafeiro, Joseph Haseman, Eugenia H. Goulding, Donna Bunch, E. Mitch Eddy, Barbara J. Davis, and Roger W. Wiseman
Cancer Res 2002 62: 990-994. [Abstract] [Full Text] [PDF]  

Recovery of Liver Mass without Proliferation of Hepatocytes after Partial Hepatectomy in Skp2-deficient Mice

Yohji A. Minamishima, Keiko Nakayama, and Kei-Ichi Nakayama
Cancer Res 2002 62: 995-999. [Abstract] [Full Text] [PDF]  

Increased Risk of Local Recurrence Is Associated with Allelic Loss in Normal Lobules of Breast Cancer Patients

Zheng Li, Dan H. Moore, Zhen Hang Meng, Britt-Marie Ljung, Joe W. Gray, and Shanaz H. Dairkee
Cancer Res 2002 62: 1000-1003. [Abstract] [Full Text] [PDF]  

The Nonsteroidal Anti-inflammatory Drug Sulindac Causes Down-Regulation of Signal Transducer and Activator of Transcription 3 in Human Oral Squamous Cell Carcinoma Cells

Nikolaos G. Nikitakis, Anne W. Hamburger, and John J. Sauk
Cancer Res 2002 62: 1004-1007. [Abstract] [Full Text] [PDF]  

Disruption of Androgen Receptor Function Inhibits Proliferation of Androgen-refractory Prostate Cancer Cells

Ofelia L. Zegarra-Moro, Lucy J. Schmidt, Haojie Huang, and Donald J. Tindall
Cancer Res 2002 62: 1008-1013. [Abstract] [Full Text] [PDF]  

Exclusion of Breast Cancer as an Integral Tumor of Hereditary Nonpolyposis Colorectal Cancer

Annegret Müller, Tina Bocker Edmonston, Diana A. Corao, Deborah G. Rose, Juan P. Palazzo, Heinz Becker, Robert D. Fry, Josef Rueschoff, and Richard Fishel
Cancer Res 2002 62: 1014-1019. [Abstract] [Full Text] [PDF]  

Early Placenta Insulin-like Growth Factor (pro-EPIL) Is Overexpressed and Secreted by c-erbB-2-positive Cells with High Invasion Potential

Burkhard Brandt, Antje Roetger, Jean-Michel Bidart, Jens Packeisen, Katrin Schier, Jan-Hendrik Mikesch, Dirk Kemming, Werner Boecker, Dihua Yu, and Horst Buerger
Cancer Res 2002 62: 1020-1024. [Abstract] [Full Text] [PDF]  

Biochemistry and Biophysics:

Inhibition of Activator Protein-1 Binding Activity and Phosphatidylinositol 3-Kinase Pathway by Nobiletin, a Polymethoxy Flavonoid, Results in Augmentation of Tissue Inhibitor of Metalloproteinases-1 Production and Suppression of Production of Matrix Metalloproteinases-1 and -9 in Human Fibrosarcoma HT-1080 Cells

Takashi Sato, Leona Koike, Yoshiki Miyata, Michiko Hirata, Yoshihiro Mimaki, Yutaka Sashida, Masamichi Yano, and Akira Ito
Cancer Res 2002 62: 1025-1029. [Abstract] [Full Text] [PDF]  

Clinical Investigations:

Circulating Insulin-like Growth Factor-I Levels Regulate Colon Cancer Growth and Metastasis

Yiping Wu, Shoshana Yakar, Ling Zhao, Lothar Hennighausen, and Derek LeRoith
Cancer Res 2002 62: 1030-1035. [Abstract] [Full Text] [PDF]  

Endocrinology:

Two Forms of Gonadotropin-releasing Hormone (GnRH) Are Expressed in Human Breast Tissue and Overexpressed in Breast Cancer: A Putative Mechanism for the Antiproliferative Effect of GnRH by Down-Regulation of Acidic Ribosomal Phosphoproteins P1 and P2

Alon Chen, Ella Kaganovsky, Shai Rahimipour, Nurit Ben-Aroya, Eli Okon, and Yitzhak Koch
Cancer Res 2002 62: 1036-1044. [Abstract] [Full Text] [PDF]  

Epidemiology and Prevention:

The Androgen Receptor CAG Repeat Polymorphism and Risk of Breast Cancer in the Nurses’ Health Study

Christopher A. Haiman, Myles Brown, Susan E. Hankinson, Donna Spiegelman, Graham A. Colditz, Walter C. Willett, Philip W. Kantoff, and David J. Hunter
Cancer Res 2002 62: 1045-1049. [Abstract] [Full Text] [PDF]  

Experimental Therapeutics:

Increased Vaccination Efficiency with Apoptotic Cells by Silica-induced, Dendritic-like Cells

Delphine Massé, Cécile Voisine, Frédéric Henry, Sandrine Cordel, Isabelle Barbieux, Regis Josien, Khaled Meflah, Marc Grégoire, and Blandine Lieubeau
Cancer Res 2002 62: 1050-1056. [Abstract] [Full Text] [PDF]  

WK175, a Novel Antitumor Agent, Decreases the Intracellular Nicotinamide Adenine Dinucleotide Concentration and Induces the Apoptotic Cascade in Human Leukemia Cells

Katja Wosikowski, Karin Mattern, Isabel Schemainda, Max Hasmann, Benno Rattel, and Roland Löser
Cancer Res 2002 62: 1057-1062. [Abstract] [Full Text] [PDF]  

Targeting of Adenovirus Vectors to Tumor Cells Does Not Enable Efficient Transduction of Breast Cancer Metastases

Dmitry M. Shayakhmetov, Zong-Yi Li, Shaoheng Ni, and André Lieber
Cancer Res 2002 62: 1063-1068. [Abstract] [Full Text] [PDF]  

Apoptosis Induced by Adenovirus-mediated p53 Gene Transfer in Human Glioma Correlates with Site-specific Phosphorylation

Tadahisa Shono, Philip J. Tofilon, Timothy S. Schaefer, Dipen Parikh, Ta-Jen Liu, and Frederick F. Lang
Cancer Res 2002 62: 1069-1076. [Abstract] [Full Text] [PDF]  

The Kinase Inhibitor PP1 Blocks Tumorigenesis Induced by RET Oncogenes

Francesca Carlomagno, Donata Vitagliano, Teresa Guida, Maria Napolitano, Giancarlo Vecchio, Alfredo Fusco, Aviv Gazit, Alexander Levitzki, and Massimo Santoro
Cancer Res 2002 62: 1077-1082. [Abstract] [Full Text] [PDF]  

Proteasome Inhibitor PS-341, a Potential Therapeutic Agent for Adult T-Cell Leukemia

Chalet Tan and Thomas A. Waldmann
Cancer Res 2002 62: 1083-1086. [Abstract] [Full Text] [PDF]  

Inhibition of Phosphatidylinositol 3'-Kinase Increases Efficacy of Paclitaxel in in Vitro and in Vivo Ovarian Cancer Models

Limin Hu, Judith Hofmann, Yiling Lu, Gordon B. Mills, and Robert B. Jaffe
Cancer Res 2002 62: 1087-1092. [Abstract] [Full Text] [PDF]  

Immunology:

The CC Chemokine RANTES in Breast Carcinoma Progression: Regulation of Expression and Potential Mechanisms of Promalignant Activity

Elina Azenshtein, Galia Luboshits, Sima Shina, Eran Neumark, David Shahbazian, Miguel Weil, Nely Wigler, Iafa Keydar, and Adit Ben-Baruch
Cancer Res 2002 62: 1093-1102. [Abstract] [Full Text] [PDF]  

IL-13R2, a Decoy Receptor for IL-13 Acts As an Inhibitor of IL-4-dependent Signal Transduction in Glioblastoma Cells

Shaik Ohidar Rahaman, Pankaj Sharma, Phyllis C. Harbor, M. Javad Aman, Michael A. Vogelbaum, and S. Jaharul Haque
Cancer Res 2002 62: 1103-1109. [Abstract] [Full Text] [PDF]  

A Tumor-expressed Inhibitor of the Early but not Late Complement Lytic Pathway Enhances Tumor Growth in a Rat Model of Human Breast Cancer

Theresa A. Caragine, Noriko Okada, Alan B. Frey, and Stephen Tomlinson
Cancer Res 2002 62: 1110-1115. [Abstract] [Full Text] [PDF]  

Apoptosis-dependent Subversion of the T-Lymphocyte Epitope Hierarchy in Lymphoma Cells

Paola Castiglioni, Alfonso Martin-Fontecha, Gabriella Milan, Valentina Tomajer, Fulvio Magni, Jakob Michaelsson, Claudio Rugarli, Antonio Rosato, and Matteo Bellone
Cancer Res 2002 62: 1116-1122. [Abstract] [Full Text] [PDF]  

Molecular Biology and Genetics:

Minichromosome Maintenance Protein MCM7 Is a Direct Target of the MYCN Transcription Factor in Neuroblastoma

Jason M. Shohet, M. John Hicks, Sharon E. Plon, Susan M. Burlingame, Susan Stuart, Si-Yi Chen, Malcolm K. Brenner, and Jed G. Nuchtern
Cancer Res 2002 62: 1123-1128. [Abstract] [Full Text] [PDF]  

Targeted Inactivation of p53 in Human Cells Does Not Result in Aneuploidy

Fred Bunz, Christine Fauth, Michael R. Speicher, Annie Dutriaux, John M. Sedivy, Kenneth W. Kinzler, Bert Vogelstein, and Christoph Lengauer
Cancer Res 2002 62: 1129-1133. [Abstract] [Full Text] [PDF]  

Silence of Chromosomal Amplifications in Colon Cancer

Petra Platzer, Madhvi B. Upender, Keith Wilson, Joseph Willis, James Lutterbaugh, Arman Nosrati, James K. V. Willson, David Mack, Thomas Ried, and Sanford Markowitz
Cancer Res 2002 62: 1134-1138. [Abstract] [Full Text] [PDF]  

An Integrated Database of Chemosensitivity to 55 Anticancer Drugs and Gene Expression Profiles of 39 Human Cancer Cell Lines

Shingo Dan, Tatsuhiko Tsunoda, Osamu Kitahara, Rempei Yanagawa, Hitoshi Zembutsu, Toyomasa Katagiri, Kanami Yamazaki, Yusuke Nakamura, and Takao Yamori
Cancer Res 2002 62: 1139-1147. [Abstract] [Full Text] [PDF]  

Hypermethylation of the p14^ARF Gene in Ulcerative Colitis-associated Colorectal Carcinogenesis

Fumiaki Sato, Noam Harpaz, David Shibata, Yan Xu, Jing Yin, Yuriko Mori, Tong-Tong Zou, Suna Wang, Kena Desai, Anatoly Leytin, Florin M. Selaru, John M. Abraham, and Stephen J. Meltzer
Cancer Res 2002 62: 1148-1151. [Abstract] [Full Text] [PDF]  

Specific Chromosomal Aberrations in Mouse Lung Adenocarcinoma Cell Lines Detected by Spectral Karyotyping: A Comparison with Human Lung Adenocarcinoma

Linda M. Sargent, Jamie R. Senft, David T. Lowry, Amy M. Jefferson, Frederick L. Tyson, Alvin M. Malkinson, Allen E. Coleman, and Steven H. Reynolds
Cancer Res 2002 62: 1152-1157. [Abstract] [Full Text] [PDF]  

Repression of -Fetoprotein Gene Expression under Hypoxic Conditions in Human Hepatoma Cells: Characterization of a Negative Hypoxia Response Element That Mediates Opposite Effects of Hypoxia Inducible Factor-1 and c-Myc

Nathalie M. Mazure, Caroline Chauvet, Brigitte Bois-Joyeux, Marguerite-Anne Bernard, Habib Nacer-Chérif, and Jean-Louis Danan
Cancer Res 2002 62: 1158-1165. [Abstract] [Full Text] [PDF]  

Low-Level Microsatellite Instability in Most Colorectal Carcinomas

Päivi Laiho, Virpi Launonen, Päivi Lahermo, Manel Esteller, Mingzhou Guo, James G. Herman, Jukka-Pekka Mecklin, Heikki Järvinen, Pertti Sistonen, Kyoung-Mee Kim, Darryl Shibata, Richard S. Houlston, and Lauri A. Aaltonen
Cancer Res 2002 62: 1166-1170. [Abstract] [Full Text] [PDF]  

Tumor Biology:

Human Tumor Suppressor ARF Impedes S-Phase Progression Independent of p53

Wendell G. Yarbrough, Mika Bessho, Adam Zanation, John E. Bisi, and Yue Xiong
Cancer Res 2002 62: 1171-1177. [Abstract] [Full Text] [PDF]  

GATA-6 Transcriptional Regulation of 15-Lipoxygenase-1 during NSAID-induced Apoptosis in Colorectal Cancer Cells

Imad Shureiqi, Wei Jiang, Susan M. Fischer, Xiaochun Xu, Dongning Chen, J. Jack Lee, Reuben Lotan, and Scott M. Lippman
Cancer Res 2002 62: 1178-1183. [Abstract] [Full Text] [PDF]  

Molecular Classification of Head and Neck Squamous Cell Carcinoma Using cDNA Microarrays

Thomas J. Belbin, Bhuvanesh Singh, Ilana Barber, Nicholas Socci, Bruce Wenig, Richard Smith, Michael B. Prystowsky, and Geoffrey Childs
Cancer Res 2002 62: 1184-1190. [Abstract] [Full Text] [PDF]  

Overexpression of Thrombospondin-1 Reduces Growth and Vascular Index but not Perfusion in Glioblastoma

Michael Kragh, Bjørn Quistorff, Mirna Tenan, Erwin G. Van Meir, and Paul E. G. Kristjansen
Cancer Res 2002 62: 1191-1195. [Abstract] [Full Text] [PDF]  

retSDR1, a Short-Chain Retinol Dehydrogenase/Reductase, Is Retinoic Acid-inducible and Frequently Deleted in Human Neuroblastoma Cell Lines

Fabio Cerignoli, Xiaojia Guo, Beatrice Cardinali, Christian Rinaldi, Jessica Casaletto, Luigi Frati, Isabella Screpanti, Lorraine J. Gudas, Alberto Gulino, Carol J. Thiele, and Giuseppe Giannini
Cancer Res 2002 62: 1196-1204. [Abstract] [Full Text] [PDF]  

Overexpression of Copper Zinc Superoxide Dismutase Suppresses Human Glioma Cell Growth

Ying Zhang, Weiling Zhao, Hannah J. Zhang, Frederick E. Domann, and Larry W. Oberley
Cancer Res 2002 62: 1205-1212. [Abstract] [Full Text] [PDF]  

Activation of Nuclear Factor B in Radioresistance of TP53-inactive Human Keratinocytes

Xufeng Chen, Binghui Shen, Liqun Xia, Alexander Khaletzkiy, David Chu, Jeffrey Y. C. Wong, and Jian-Jian Li
Cancer Res 2002 62: 1213-1221. [Abstract] [Full Text] [PDF]  

The RING Domain of Mdm2 Can Inhibit Cell Proliferation

Jinjun Dang, Mei-Ling Kuo, Christine M. Eischen, Lilia Stepanova, Charles J. Sherr, and Martine F. Roussel
Cancer Res 2002 62: 1222-1230. [Abstract] [Full Text] [PDF]  

Correction:

Y-J. Chun et al., 61: 8164–8170, 2001.

Cancer Res 2002 62: 1232 [Full Text] [PDF]  

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