Priority Reports:

Genome-Wide Single Nucleotide Polymorphism Analysis Reveals Frequent Partial Uniparental Disomy Due to Somatic Recombination in Acute Myeloid Leukemias

Manoj Raghavan, Debra M. Lillington, Spyros Skoulakis, Silvana Debernardi, Tracy Chaplin, Nicola J. Foot, T. Andrew Lister, and Bryan D. Young
Cancer Res 2005 65: 375-378. [Abstract] [Full Text] [PDF]  

Cellular Targets of Gefitinib

Dirk Brehmer, Zoltán Greff, Klaus Godl, Stephanie Blencke, Alexander Kurtenbach, Martina Weber, Stefan Müller, Bert Klebl, Matt Cotten, György Kéri, Josef Wissing, and Henrik Daub
Cancer Res 2005 65: 379-382. [Abstract] [Full Text] [PDF] Supplementary Data  

Germ Line Fanconi Anemia Complementation Group C Mutations and Pancreatic Cancer

Fergus J. Couch, Michele R. Johnson, Kari Rabe, Lisa Boardman, Robert McWilliams, Mariza de Andrade, and Gloria Petersen
Cancer Res 2005 65: 383-386. [Abstract] [Full Text] [PDF]  

Synergism between the Anticancer Actions of 2-Methoxyestradiol and Microtubule-Disrupting Agents in Human Breast Cancer

Gui-Zhen Han, Zhi-Jian Liu, Kayoko Shimoi, and Bao Ting Zhu
Cancer Res 2005 65: 387-393. [Abstract] [Full Text] [PDF]  

Molecular Biology, Pathobiology and Genetics:

Characterization of -Aminobutyric Acid Type A Receptor–Associated Protein, a Novel Tumor Suppressor, Showing Reduced Expression in Breast Cancer

Christiane Klebig, Susanne Seitz, Wolfgang Arnold, Nicole Deutschmann, Manuela Pacyna-Gengelbach, Siegfried Scherneck, and Iver Petersen
Cancer Res 2005 65: 394-400. [Abstract] [Full Text] [PDF]  

Global Analysis of Altered Gene Expressions during the Process of Esophageal Squamous Cell Carcinogenesis in the Rat: A Study Combined with a Laser Microdissection and a cDNA Microarray

Koujiro Nishida, Shinji Mine, Tohru Utsunomiya, Hiroshi Inoue, Masahiro Okamoto, Harushi Udagawa, Taizo Hanai, and Masaki Mori
Cancer Res 2005 65: 401-409. [Abstract] [Full Text] [PDF]  

Mutations in Apc and p53 Synergize to Promote Mammary Neoplasia

Valérie Méniel, Trevor Hay, Anthony Douglas-Jones, Owen J. Sansom, and Alan R. Clarke
Cancer Res 2005 65: 410-416. [Abstract] [Full Text] [PDF] Supplementary Data  

Functional Evaluation and Cancer Risk Assessment of BRCA2 Unclassified Variants

Kangjian Wu, Shannon R. Hinson, Akihiro Ohashi, Daniel Farrugia, Patricia Wendt, Sean V. Tavtigian, Amie Deffenbaugh, David Goldgar, and Fergus J. Couch
Cancer Res 2005 65: 417-426. [Abstract] [Full Text] [PDF] Supplementary Data  

Genetic Mapping of a Third Li-Fraumeni Syndrome Predisposition Locus to Human Chromosome 1q23

Linda L. Bachinski, Shodimu-Emmanuel Olufemi, Xiaojun Zhou, Chih-Chieh Wu, Linwah Yip, Sanjay Shete, Guillermina Lozano, Christopher I. Amos, Louise C. Strong, and Ralf Krahe
Cancer Res 2005 65: 427-431. [Abstract] [Full Text] [PDF]  

Differential Role of Transcription-Coupled Repair in UVB–Induced Response of Human Fibroblasts and Keratinocytes

Mariarosaria D'Errico, Massimo Teson, Angelo Calcagnile, Tiziana Nardo, Naomi De Luca, Chiara Lazzari, Silvia Soddu, Giovanna Zambruno, Miria Stefanini, and Eugenia Dogliotti
Cancer Res 2005 65: 432-438. [Abstract] [Full Text] [PDF]  

Candidate Genes in Breast Cancer Revealed by Microarray-Based Comparative Genomic Hybridization of Archived Tissue

Michelle Nessling, Karsten Richter, Carsten Schwaenen, Peter Roerig, Gunnar Wrobel, Swen Wessendorf, Björn Fritz, Martin Bentz, Hans-Peter Sinn, Bernhard Radlwimmer, and Peter Lichter
Cancer Res 2005 65: 439-447. [Abstract] [Full Text] [PDF] Supplementary Data  

Cell and Tumor Biology:

Bone Morphogenic Proteins Are Overexpressed in Malignant Melanoma and Promote Cell Invasion and Migration

Tanja Rothhammer, Ina Poser, Fabrice Soncin, Frauke Bataille, Markus Moser, and Anja-Katrin Bosserhoff
Cancer Res 2005 65: 448-456. [Abstract] [Full Text] [PDF]  

Antiapoptotic Effect of Serum and Glucocorticoid-Inducible Protein Kinase Is Mediated by Novel Mechanism Activating IB Kinase

Liping Zhang, Ruwen Cui, Xiaodong Cheng, and Jie Du
Cancer Res 2005 65: 457-464. [Abstract] [Full Text] [PDF]  

CXCL12 and Vascular Endothelial Growth Factor Synergistically Induce Neoangiogenesis in Human Ovarian Cancers

Ilona Kryczek, Andrzej Lange, Peter Mottram, Xavier Alvarez, Pui Cheng, Melina Hogan, Lieve Moons, Shuang Wei, Linhua Zou, Véronique Machelon, Dominique Emilie, Margarita Terrassa, Andrew Lackner, Tyler J. Curiel, Peter Carmeliet, and Weiping Zou
Cancer Res 2005 65: 465-472. [Abstract] [Full Text] [PDF]  

Decreased Accessibility and Lack of Activation of ErbB2 in JIMT-1, a Herceptin-Resistant, MUC4-Expressing Breast Cancer Cell Line

Peter Nagy, Elza Friedländer, Minna Tanner, Anita I. Kapanen, Kermit L. Carraway, Jorma Isola, and Thomas M. Jovin
Cancer Res 2005 65: 473-482. [Abstract] [Full Text] [PDF]  

E-Cadherin Phosphorylation by Protein Kinase D1/Protein Kinase Cµ is Associated with Altered Cellular Aggregation and Motility in Prostate Cancer

Meena Jaggi, Prema S. Rao, David J. Smith, Margaret J. Wheelock, Keith R. Johnson, George P. Hemstreet, and K.C. Balaji
Cancer Res 2005 65: 483-492. [Abstract] [Full Text] [PDF]  

Calcium Sensing Receptor in Human Colon Carcinoma: Interaction with Ca²⁺ and 1,25-Dihydroxyvitamin D₃

Subhas Chakrabarty, Hongmei Wang, Lucie Canaff, Geoffrey N. Hendy, Henry Appelman, and James Varani
Cancer Res 2005 65: 493-498. [Abstract] [Full Text] [PDF]  

The Serum Glycoprotein Fetuin-A Promotes Lewis Lung Carcinoma Tumorigenesis via Adhesive-Dependent and Adhesive-Independent Mechanisms

Madappa N. Kundranda, Melodie Henderson, Kathy J. Carter, Lee Gorden, Awadh Binhazim, Sanhita Ray, Trevor Baptiste, Masih Shokrani, Maria L. Leite-Browning, Willi Jahnen-Dechent, Lynn M. Matrisian, and Josiah Ochieng
Cancer Res 2005 65: 499-506. [Abstract] [Full Text] [PDF]  

The COOH-terminal End of R-Ras Alters the Motility and Morphology of Breast Epithelial Cells through Rho/Rho-Kinase

Ha-Won Jeong, Ju-Ock Nam, and In-San Kim
Cancer Res 2005 65: 507-515. [Abstract] [Full Text] [PDF]  

Nitric Oxide Reverts the Resistance to Doxorubicin in Human Colon Cancer Cells by Inhibiting the Drug Efflux

Chiara Riganti, Erica Miraglia, Daniele Viarisio, Costanzo Costamagna, Gianpiero Pescarmona, Dario Ghigo, and Amalia Bosia
Cancer Res 2005 65: 516-525. [Abstract] [Full Text] [PDF]  

Activation of the ß-Catenin/T-Cell–Specific Transcription Factor/Lymphoid Enhancer Factor-1 Pathway by Plasminogen Activators in ECV304 Carcinoma Cells

Françoise Maupas-Schwalm, Catherine Robinet, Nathalie Augé, Jean-Claude Thiers, Virginie Garcia, Jean-Pierre Cambus, Robert Salvayre, and Anne Nègre-Salvayre
Cancer Res 2005 65: 526-532. [Abstract] [Full Text] [PDF]  

Experimental Therapeutics, Molecular Targets, and Chemical Biology:

Ultrasonic Imaging of Tumor Angiogenesis Using Contrast Microbubbles Targeted via the Tumor-Binding Peptide Arginine-Arginine-Leucine

Gregory E.R. Weller, Michael K.K. Wong, Ruth A. Modzelewski, Erxiong Lu, Alexander L. Klibanov, William R. Wagner, and Flordeliza S. Villanueva
Cancer Res 2005 65: 533-539. [Abstract] [Full Text] [PDF]  

Alendronate Inhibits Intraperitoneal Dissemination in In vivo Ovarian Cancer Model

Kae Hashimoto, Ken-ichirou Morishige, Kenjiro Sawada, Masahiro Tahara, Rikako Kawagishi, Yoshihide Ikebuchi, Masahiro Sakata, Keiichi Tasaka, and Yuji Murata
Cancer Res 2005 65: 540-545. [Abstract] [Full Text] [PDF]  

Effective Gene Therapy of Biliary Tract Cancers by a Conditionally Replicative Adenovirus Expressing Uracil Phosphoribosyltransferase: Significance of Timing of 5-Fluorouracil Administration

Emiko Seo, Masato Abei, Mariko Wakayama, Kuniaki Fukuda, Hideyo Ugai, Takehide Murata, Takeshi Todoroki, Yasushi Matsuzaki, Naomi Tanaka, Hirofumi Hamada, and Kazunari K. Yokoyama
Cancer Res 2005 65: 546-552. [Abstract] [Full Text] [PDF]  

A DNA Vaccine Targeting Survivin Combines Apoptosis with Suppression of Angiogenesis in Lung Tumor Eradication

Rong Xiang, Noriko Mizutani, Yunping Luo, Claudia Chiodoni, He Zhou, Masato Mizutani, Yi Ba, Juergen C. Becker, and Ralph A. Reisfeld
Cancer Res 2005 65: 553-561. [Abstract] [Full Text] [PDF]  

Antisense Suppression of the Chloride Intracellular Channel Family Induces Apoptosis, Enhances Tumor Necrosis Factor -Induced Apoptosis, and Inhibits Tumor Growth

Kwang S. Suh, Michihiro Mutoh, Michael Gerdes, John M. Crutchley, Tomoko Mutoh, Lindsay E. Edwards, Rebecca A. Dumont, Pooja Sodha, Christina Cheng, Adam Glick,, and Stuart H. Yuspa
Cancer Res 2005 65: 562-571. [Abstract] [Full Text] [PDF]  

Induction of Ornithine Decarboxylase Activity Is a Necessary Step for Mitogen-Activated Protein Kinase Kinase–Induced Skin Tumorigenesis

David J. Feith, David K. Bol, Joan M. Carboni, Mark J. Lynch, Suzanne Sass-Kuhn, Paula L. Shoop, and Lisa M. Shantz
Cancer Res 2005 65: 572-578. [Abstract] [Full Text] [PDF]  

Effects of Hypoxia on Radiation-Responsive Stress-Activated Protein Kinase, p53, and Caspase 3 Signals in TK6 Human Lymphoblastoid Cells

Ayelet M. Samuni, Usha Kasid, Eric Y. Chuang, Simeng Suy, William DeGraff, Murali C. Krishna, Angelo Russo, and James B. Mitchell
Cancer Res 2005 65: 579-586. [Abstract] [Full Text] [PDF]  

Retinoic Acid Inhibits the Proliferative Response Induced by CD40 Activation and Interleukin-4 in Mantle Cell Lymphoma

Massimo Guidoboni, Paola Zancai, Roberta Cariati, Silvana Rizzo, Jessica Dal Col, Alessandro Pavan, Annunziata Gloghini, Michele Spina, Antonio Cuneo, Fabrizio Pomponi, Antonio Bononi, Claudio Doglioni, Roberta Maestro, Antonino Carbone, Mauro Boiocchi, and Riccardo Dolcetti
Cancer Res 2005 65: 587-595. [Abstract] [Full Text] [PDF]  

Estrogen-Mediated Post transcriptional Down-regulation of Breast Cancer Resistance Protein/ABCG2

Yasuo Imai, Etsuko Ishikawa, Sakiyo Asada, and Yoshikazu Sugimoto
Cancer Res 2005 65: 596-604. [Abstract] [Full Text] [PDF]  

Identification of a Novel Small-Molecule Inhibitor of the Hypoxia-Inducible Factor 1 Pathway

Chalet Tan, Rita G. de Noronha, Anthony J. Roecker, Beata Pyrzynska, Fatima Khwaja, Zhaobin Zhang, Huanchun Zhang, Quincy Teng, Ainsley C. Nicholson, Paraskevi Giannakakou, Wei Zhou, Jeffrey J. Olson, M. Manuela Pereira, K.C. Nicolaou, and Erwin G. Van Meir
Cancer Res 2005 65: 605-612. [Abstract] [Full Text] [PDF]  

Inhibition of Glycolysis in Cancer Cells: A Novel Strategy to Overcome Drug Resistance Associated with Mitochondrial Respiratory Defect and Hypoxia

Rui-hua Xu, Helene Pelicano, Yan Zhou, Jennifer S. Carew, Li Feng, Kapil N. Bhalla, Michael J. Keating, and Peng Huang
Cancer Res 2005 65: 613-621. [Abstract] [Full Text] [PDF]  

Immunology:

Tailoring the Pharmacokinetics and Positron Emission Tomography Imaging Properties of Anti–Carcinoembryonic Antigen Single-Chain Fv-Fc Antibody Fragments

Vania Kenanova, Tove Olafsen, Desiree M. Crow, Gobalakrishnan Sundaresan, Murugesan Subbarayan, Nora H. Carter, David N. Ikle, Paul J. Yazaki, Arion F. Chatziioannou, Sanjiv S. Gambhir, Lawrence E. Williams, John E. Shively, David Colcher, Andrew A. Raubitschek, and Anna M. Wu
Cancer Res 2005 65: 622-631. [Abstract] [Full Text] [PDF]  

Immunogenicity without Immunoselection: A Mutant but Functional Antioxidant Enzyme Retained in a Human Metastatic Melanoma and Targeted by CD8⁺ T Cells with a Memory Phenotype

Marialuisa Sensi, Gabriella Nicolini, Marina Zanon, Chiara Colombo, Alessandra Molla, Ilaria Bersani, Raffaella Lupetti, Giorgio Parmiani, and Andrea Anichini
Cancer Res 2005 65: 632-640. [Abstract] [Full Text] [PDF]  

Eradication of Established Tumors by Vaccination With Recombinant Bordetella pertussis Adenylate Cyclase Carrying the Human Papillomavirus 16 E7 Oncoprotein

Xavier Préville, Daniel Ladant, Benedikt Timmerman, and Claude Leclerc
Cancer Res 2005 65: 641-649. [Abstract] [Full Text] [PDF]  

Endogenous Anti-HER2 Antibodies Block HER2 Phosphorylation and Signaling through Extracellular Signal-Regulated Kinase

R. Bruce Montgomery, Ekram Makary, Kathy Schiffman, Vivian Goodell, and Mary L. Disis
Cancer Res 2005 65: 650-656. [Abstract] [Full Text] [PDF]  

Endocrinology:

Interactions between Prostaglandin E₂, Liver Receptor Homologue-1, and Aromatase in Breast Cancer

Jiong Zhou, Takashi Suzuki, Agnes Kovacic, Ryoko Saito, Yasuhiro Miki, Takanori Ishida, Takuya Moriya, Evan R. Simpson, Hironobu Sasano, and Colin D. Clyne
Cancer Res 2005 65: 657-663. [Abstract] [Full Text] [PDF]  

Epidemiology and Prevention:

Levels of Cyclooxygenase-2 Are Increased in the Oral Mucosa of Smokers: Evidence for the Role of Epidermal Growth Factor Receptor and Its Ligands

Dimitrios Moraitis, Baoheng Du, Mariana S. De Lorenzo, Jay O. Boyle, Babette B. Weksler, Erik G. Cohen, John F. Carew, Nasser K. Altorki, Levy Kopelovich, Kotha Subbaramaiah, and Andrew J. Dannenberg
Cancer Res 2005 65: 664-670. [Abstract] [Full Text] [PDF]  

To see an article, click its [Full Text] link. To review many abstracts, check the boxes to the left of the titles you want, and click the 'Get All Checked Abstract(s)' button. To see one abstract at a time, click its [Abstract] link.