Reviews:

Prospects for Cervical Cancer Prevention by Human Papillomavirus Vaccination

John T. Schiller and Douglas R. Lowy
Cancer Res 2006 66: 10229-10232. [Abstract] [Full Text] [PDF]  

Heparanase, Hyaluronan, and CD44 in Cancers: A Breast Carcinoma Perspective

Martin Götte and George W. Yip
Cancer Res 2006 66: 10233-10237. [Abstract] [Full Text] [PDF]  

Lysyl Oxidase Mediates Hypoxic Control of Metastasis

Janine T. Erler and Amato J. Giaccia
Cancer Res 2006 66: 10238-10241. [Abstract] [Full Text] [PDF]  

Priority Reports:

TMPRSS2 Fusions with Oncogenic ETS Factors in Prostate Cancer Involve Unbalanced Genomic Rearrangements and Are Associated with HDAC1 and Epigenetic Reprogramming

Kristiina Iljin, Maija Wolf, Henrik Edgren, Santosh Gupta, Sami Kilpinen, Rolf I. Skotheim, Mari Peltola, Frank Smit, Gerald Verhaegh, Jack Schalken, Matthias Nees, and Olli Kallioniemi
Cancer Res 2006 66: 10242-10246. [Abstract] [Full Text] [PDF] Supplementary Data  

Neurospheres Enriched in Cancer Stem–Like Cells Are Highly Effective in Eliciting a Dendritic Cell–Mediated Immune Response against Malignant Gliomas

Serena Pellegatta, Pietro Luigi Poliani, Daniela Corno, Francesca Menghi, Francesco Ghielmetti, Blanca Suarez-Merino, Valentina Caldera, Sara Nava, Maria Ravanini, Fabio Facchetti, Maria Grazia Bruzzone, and Gaetano Finocchiaro
Cancer Res 2006 66: 10247-10252. [Abstract] [Full Text] [PDF] Supplementary Data  

Adaptation to the Ionizing Radiation–Induced G₂ Checkpoint Occurs in Human Cells and Depends on Checkpoint Kinase 1 and Polo-like Kinase 1 Kinases

Randi G. Syljuåsen, Sanne Jensen, Jiri Bartek, and Jiri Lukas
Cancer Res 2006 66: 10253-10257. [Abstract] [Full Text] [PDF] Supplementary Data  

Retinoblastoma Pathway Defects Show Differential Ability to Activate the Constitutive DNA Damage Response in Human Tumorigenesis

Frederic Tort, Jirina Bartkova, Maxwell Sehested, Torben Ørntoft, Jiri Lukas, and Jiri Bartek
Cancer Res 2006 66: 10258-10263. [Abstract] [Full Text] [PDF] Supplementary Data  

Expression and Regulatory Role of GAIP-Interacting Protein GIPC in Pancreatic Adenocarcinoma

Michael H. Muders, Shamit K. Dutta, Ling Wang, Julie S. Lau, Resham Bhattacharya, Thomas C. Smyrk, Suresh T. Chari, Kaustubh Datta, and Debabrata Mukhopadhyay
Cancer Res 2006 66: 10264-10268. [Abstract] [Full Text] [PDF] Supplementary Data  

Metformin Is an AMP Kinase–Dependent Growth Inhibitor for Breast Cancer Cells

Mahvash Zakikhani, Ryan Dowling, I. George Fantus, Nahum Sonenberg, and Michael Pollak
Cancer Res 2006 66: 10269-10273. [Abstract] [Full Text] [PDF] Supplementary Data  

Nongenotoxic p53 Activation Protects Cells against S-Phase–Specific Chemotherapy

Dominique Kranz and Matthias Dobbelstein
Cancer Res 2006 66: 10274-10280. [Abstract] [Full Text] [PDF] Supplementary Data  

Aromatase Destabilizer: Novel Action of Exemestane, a Food and Drug Administration–Approved Aromatase Inhibitor

Xin Wang and Shiuan Chen
Cancer Res 2006 66: 10281-10286. [Abstract] [Full Text] [PDF]  

Alterations of the Tumor Suppressor Gene ARLTS1 in Ovarian Cancer

Fabio Petrocca, Dimitrios Iliopoulos, Haiyan R. Qin, Milena S. Nicoloso, Say Yendamuri, Sylwia E. Wojcik, Masayoshi Shimizu, Gianpiero Di Leva, Andrea Vecchione, Francesco Trapasso, Andrew K. Godwin, Massimo Negrini, George A. Calin, and Carlo M. Croce
Cancer Res 2006 66: 10287-10291. [Abstract] [Full Text] [PDF] Supplementary Data  

Molecular Biology, Pathobiology, and Genetics:

Genetic Reclassification of Histologic Grade Delineates New Clinical Subtypes of Breast Cancer

Anna V. Ivshina, Joshy George, Oleg Senko, Benjamin Mow, Thomas C. Putti, Johanna Smeds, Thomas Lindahl, Yudi Pawitan, Per Hall, Hans Nordgren, John E.L. Wong, Edison T. Liu, Jonas Bergh, Vladimir A. Kuznetsov, and Lance D. Miller
Cancer Res 2006 66: 10292-10301. [Abstract] [Full Text] [PDF] Supplementary Data  

Truncating Variants in p53AIP1 Disrupting DNA Damage–Induced Apoptosis Are Associated with Prostate Cancer Risk

Xianshu Wang, Fengwei Wang, Ken Taniguchi, Ratnam S. Seelan, Liang Wang, Katherine E. Zarfas, Shannon K. McDonnell, Chiping Qian, Kaifeng Pan, Youyong Lu, Viji Shridhar, Fergus J. Couch, Donald J. Tindall, Jennifer L. Beebe-Dimmer, Kathleen A. Cooney, William B. Isaacs, Steven J. Jacobsen, Daniel J. Schaid, Stephen N. Thibodeau, and Wanguo Liu
Cancer Res 2006 66: 10302-10307. [Abstract] [Full Text] [PDF]  

A Repressive Epigenetic Domino Effect Confers Susceptibility to Breast Epithelial Cell Transformation: Implications for Predicting Breast Cancer Risk

Gaia Bistulfi, Silvia Pozzi, MingQiang Ren, Stefano Rossetti, and Nicoletta Sacchi
Cancer Res 2006 66: 10308-10314. [Abstract] [Full Text] [PDF]  

Ephrin-A1 Facilitates Mammary Tumor Metastasis through an Angiogenesis-Dependent Mechanism Mediated by EphA Receptor and Vascular Endothelial Growth Factor in Mice

Dana M. Brantley-Sieders, Wei Bin Fang, Yoonha Hwang, Donna Hicks, and Jin Chen
Cancer Res 2006 66: 10315-10324. [Abstract] [Full Text] [PDF]  

p16^INK4a Modulates p53 in Primary Human Mammary Epithelial Cells

Jianmin Zhang, Curtis R. Pickering, Charles R. Holst, Mona L. Gauthier, and Thea D. Tlsty
Cancer Res 2006 66: 10325-10331. [Abstract] [Full Text] [PDF]  

Chromosomal Breakpoints Affecting Immunoglobulin Loci Are Recurrent in Hodgkin and Reed-Sternberg Cells of Classical Hodgkin Lymphoma

José I. Martín-Subero, Wolfram Klapper, Anna Sotnikova, Evelyne Callet-Bauchu, Lana Harder, Christian Bastard, Roland Schmitz, Susanne Grohmann, Jorge Höppner, Jennifer Riemke, Thomas F.E. Barth, Françoise Berger, Heinz-Wolfram Bernd, Alexander Claviez, Stefan Gesk, Georgiy A. Frank, Irina B. Kaplanskaya, Peter Möller, Reza M. Parwaresch, Thomas Rüdiger, Harald Stein, Ralf Küppers, Martin L. Hansmann, Reiner Siebert for the Deutsche Krebshilfe Network Project "Molecular Mechanisms in Malignant Lymphomas"
Cancer Res 2006 66: 10332-10338. [Abstract] [Full Text] [PDF] Supplementary Data  

Activation of CDCA1-KNTC2, Members of Centromere Protein Complex, Involved in Pulmonary Carcinogenesis

Satoshi Hayama, Yataro Daigo, Tatsuya Kato, Nobuhisa Ishikawa, Takumi Yamabuki, Masaki Miyamoto, Tomoo Ito, Eiju Tsuchiya, Satoshi Kondo, and Yusuke Nakamura
Cancer Res 2006 66: 10339-10348. [Abstract] [Full Text] [PDF]  

Low Dietary Folate Initiates Intestinal Tumors in Mice, with Altered Expression of G₂-M Checkpoint Regulators Polo-Like Kinase 1 and Cell Division Cycle 25c

Erin Knock, Liyuan Deng, Qing Wu, Daniel Leclerc, Xiao-ling Wang, and Rima Rozen
Cancer Res 2006 66: 10349-10356. [Abstract] [Full Text] [PDF]  

Norepinephrine Up-regulates the Expression of Vascular Endothelial Growth Factor, Matrix Metalloproteinase (MMP)-2, and MMP-9 in Nasopharyngeal Carcinoma Tumor Cells

Eric V. Yang, Anil K. Sood, Min Chen, Yang Li, Tim D. Eubank, Clay B. Marsh, Scott Jewell, Nicholas A. Flavahan, Carl Morrison, Peir-En Yeh, Stanley Lemeshow, and Ronald Glaser
Cancer Res 2006 66: 10357-10364. [Abstract] [Full Text] [PDF]  

Preparing the "Soil": The Primary Tumor Induces Vasculature Reorganization in the Sentinel Lymph Node before the Arrival of Metastatic Cancer Cells

Chao-Nan Qian, Bree Berghuis, Galia Tsarfaty, MaryBeth Bruch, Eric J. Kort, Jon Ditlev, Ilan Tsarfaty, Eric Hudson, David G. Jackson, David Petillo, Jindong Chen, James H. Resau, and Bin Tean Teh
Cancer Res 2006 66: 10365-10376. [Abstract] [Full Text] [PDF] Supplementary Data  

A Role for Mitochondrial Dysfunction in Perpetuating Radiation-Induced Genomic Instability

Grace J. Kim, Gary M. Fiskum, and William F. Morgan
Cancer Res 2006 66: 10377-10383. [Abstract] [Full Text] [PDF]  

Mapping a Sex Hormone–Sensitive Gene Determining Female Resistance to Liver Carcinogenesis in a Congenic F344.BN-Hcs4 Rat

Maria R. De Miglio, Patrizia Virdis, Diego F. Calvisi, Maddalena Frau, Maria R. Muroni, Maria M. Simile, Lucia Daino, Giovanni M. Careddu, Eraldo Sanna-Passino, Rosa M. Pascale, and Francesco Feo
Cancer Res 2006 66: 10384-10390. [Abstract] [Full Text] [PDF] Supplementary Data  

Cell, Tumor, and Stem Cell Biology:

Effect of c-neu/ ErbB2 Expression Levels on Estrogen Receptor –Dependent Proliferation in Mammary Epithelial Cells: Implications for Breast Cancer Biology

Gopalan Shyamala, Yu-Chien Chou, Robert D. Cardiff, and Elizabeth Vargis
Cancer Res 2006 66: 10391-10398. [Abstract] [Full Text] [PDF]  

Loss of Nkx2.8 Deregulates Progenitor Cells in the Large Airways and Leads to Dysplasia

Jianmin Tian, Radma Mahmood, Robert Hnasko, and Joseph Locker
Cancer Res 2006 66: 10399-10407. [Abstract] [Full Text] [PDF] Supplementary Data  

Membrane Ganglioside Enrichment Lowers the Threshold for Vascular Endothelial Cell Angiogenic Signaling

Yihui Liu, James McCarthy, and Stephan Ladisch
Cancer Res 2006 66: 10408-10414. [Abstract] [Full Text] [PDF] Supplementary Data  

Tumorigenic Conversion of Primary Human Esophageal Epithelial Cells Using Oncogene Combinations in the Absence of Exogenous Ras

Seok-Hyun Kim, Hiroshi Nakagawa, Arunasalam Navaraj, Yoshio Naomoto, Andres J.P. Klein-Szanto, Anil K. Rustgi, and Wafik S. El-Deiry
Cancer Res 2006 66: 10415-10424. [Abstract] [Full Text] [PDF] Supplementary Data  

Disulfiram, a Clinically Used Anti-Alcoholism Drug and Copper-Binding Agent, Induces Apoptotic Cell Death in Breast Cancer Cultures and Xenografts via Inhibition of the Proteasome Activity

Di Chen, Qiuzhi Cindy Cui, Huanjie Yang, and Q. Ping Dou
Cancer Res 2006 66: 10425-10433. [Abstract] [Full Text] [PDF]  

A Conserved RAS/Mitogen-Activated Protein Kinase Pathway Regulates DNA Damage–Induced Cell Death Postirradiation in Radelegans

Joanne B. Weidhaas, David M. Eisenmann, Justin M. Holub, and Sunitha V. Nallur
Cancer Res 2006 66: 10434-10438. [Abstract] [Full Text] [PDF] Supplementary Data  

Expression of Wnt-5a Is Correlated with Aggressiveness of Gastric Cancer by Stimulating Cell Migration and Invasion

Manabu Kurayoshi, Naohide Oue, Hideki Yamamoto, Michiko Kishida, Atsuko Inoue, Toshimasa Asahara, Wataru Yasui, and Akira Kikuchi
Cancer Res 2006 66: 10439-10448. [Abstract] [Full Text] [PDF]  

Inappropriate Activation of the Androgen Receptor by Nonsteroids: Involvement of the Src Kinase Pathway and Its Therapeutic Implications

Sonal J. Desai, Ai-Hong Ma, Clifford G. Tepper, Hong-Wu Chen, and Hsing-Jien Kung
Cancer Res 2006 66: 10449-10459. [Abstract] [Full Text] [PDF] Supplementary Data  

Membrane Type-1 Matrix Metalloproteinase Confers Aneuploidy and Tumorigenicity on Mammary Epithelial Cells

Vladislav S. Golubkov, Alexey V. Chekanov, Alexey Y. Savinov, Dmitri V. Rozanov, Natalya V. Golubkova, and Alex Y. Strongin
Cancer Res 2006 66: 10460-10465. [Abstract] [Full Text] [PDF] Supplementary Data  

Identification and Functional Characterization of a Novel Unspliced Transcript Variant of HIC-1 in Human Cancer Cells Exposed to Adverse Growth Conditions

Abdul Matin Mondal, Sivasamy Chinnadurai, Kamal Datta, Shyam S. Chauhan, Subrata Sinha, and Parthaprasad Chattopadhyay
Cancer Res 2006 66: 10466-10477. [Abstract] [Full Text] [PDF] Supplementary Data  

A Novel Anticancer Gold(III) Dithiocarbamate Compound Inhibits the Activity of a Purified 20S Proteasome and 26S Proteasome in Human Breast Cancer Cell Cultures and Xenografts

Vesna Milacic, Di Chen, Luca Ronconi, Kristin R. Landis-Piwowar, Dolores Fregona, and Q. Ping Dou
Cancer Res 2006 66: 10478-10486. [Abstract] [Full Text] [PDF]  

Activating Transcription Factor 2 Mediates Matrix Metalloproteinase-2 Transcriptional Activation Induced by p38 in Breast Epithelial Cells

Hyun Song, Sung Hwan Ki, Sang Geon Kim, and Aree Moon
Cancer Res 2006 66: 10487-10496. [Abstract] [Full Text] [PDF] Supplementary Data  

Combined Stimulation with Interleukin-18 and CpG Induces Murine Natural Killer Dendritic Cells to Produce IFN- and Inhibit Tumor Growth

Umer I. Chaudhry, T. Peter Kingham, George Plitas, Steven C. Katz, Jesse R. Raab, and Ronald P. DeMatteo
Cancer Res 2006 66: 10497-10504. [Abstract] [Full Text] [PDF]  

Ras Induces Chromosome Instability and Abrogation of the DNA Damage Response

Adili Abulaiti, Aphrothiti J. Fikaris, Oxana M. Tsygankova, and Judy L. Meinkoth
Cancer Res 2006 66: 10505-10512. [Abstract] [Full Text] [PDF]  

Experimental Therapeutics, Molecular Targets, and Chemical Biology:

Transgenic Mouse Model for Rapid Pharmacodynamic Evaluation of Antiandrogens

Katharine Ellwood-Yen, John Wongvipat, and Charles Sawyers
Cancer Res 2006 66: 10513-10516. [Abstract] [Full Text] [PDF]  

Interleukin-6 Contributes to Growth in Cholangiocarcinoma Cells by Aberrant Promoter Methylation and Gene Expression

Hania Wehbe, Roger Henson, Fanyin Meng, Janna Mize-Berge, and Tushar Patel
Cancer Res 2006 66: 10517-10524. [Abstract] [Full Text] [PDF]  

Increased Expression of Tissue Transglutaminase in Pancreatic Ductal Adenocarcinoma and Its Implications in Drug Resistance and Metastasis

Amit Verma, Huamin Wang, Bramanandam Manavathi, Jansina Y. Fok, Aman P. Mann, Rakesh Kumar, and Kapil Mehta
Cancer Res 2006 66: 10525-10533. [Abstract] [Full Text] [PDF]  

Targeting Cancer Cells by Novel Engineered Modular Transporters

Dinara G. Gilyazova, Andrey A. Rosenkranz, Pavel V. Gulak, Vladimir G. Lunin, Olga V. Sergienko, Yuri V. Khramtsov, Kirill N. Timofeyev, Mikhail A. Grin, Andrey F. Mironov, Andrey B. Rubin, Georgii P. Georgiev, and Alexander S. Sobolev
Cancer Res 2006 66: 10534-10540. [Abstract] [Full Text] [PDF] Supplementary Data  

The Urinary Metabolite Profile of the Dietary Carcinogen 2-Amino-1-Methyl-6-Phenylimidazo[4,5-b]Pyridine Is Predictive of Colon DNA Adducts after a Low-Dose Exposure in Humans

Michael A. Malfatti, Karen H. Dingley, Susan Nowell-Kadlubar, Esther A. Ubick, Nisha Mulakken, David Nelson, Nicholas P. Lang, James S. Felton, and Kenneth W. Turteltaub
Cancer Res 2006 66: 10541-10547. [Abstract] [Full Text] [PDF]  

Receptor-Mediated DNA-Targeted Photoimmunotherapy

Tom C. Karagiannis, Pavel N. Lobachevsky, Brenda K.Y. Leung, Jonathan M. White, and Roger F. Martin
Cancer Res 2006 66: 10548-10552. [Abstract] [Full Text] [PDF] Supplementary Data  

Potentiation of the Effect of Erlotinib by Genistein in Pancreatic Cancer: The Role of Akt and Nuclear Factor-B

Basil F. El-Rayes, Shadan Ali, Ifrah F. Ali, Philip A. Philip, James Abbruzzese, and Fazlul H. Sarkar
Cancer Res 2006 66: 10553-10559. [Abstract] [Full Text] [PDF]  

Modulation of Oncogenic Transcription and Alternative Splicing by ß-Catenin and an RNA Aptamer in Colon Cancer Cells

Hee Kyu Lee, Yong Seok Choi, Young Ae Park, and Sunjoo Jeong
Cancer Res 2006 66: 10560-10566. [Abstract] [Full Text] [PDF]  

Immunology:

Characterization of GD2 Peptide Mimotope DNA Vaccines Effective against Spontaneous Neuroblastoma Metastases

Stefan Fest, Nicole Huebener, Silke Weixler, Matthias Bleeke, Yan Zeng, Anne Strandsby, Rudolf Volkmer-Engert, Christiane Landgraf, Gerhard Gaedicke, Angelika B. Riemer, Elke Michalsky, Ines S. Jaeger, Robert Preissner, Elisabeth Förster-Wald, Erika Jensen-Jarolim, and Holger N. Lode
Cancer Res 2006 66: 10567-10575. [Abstract] [Full Text] [PDF]  

Distinct Roles for IFN Regulatory Factor (IRF)-3 and IRF-7 in the Activation of Antitumor Properties of Human Macrophages

Raphaëlle Romieu-Mourez, Mayra Solis, Alessandra Nardin, Delphine Goubau, Véronique Baron-Bodo, Rongtuan Lin, Bernard Massie, Margarita Salcedo, and John Hiscott
Cancer Res 2006 66: 10576-10585. [Abstract] [Full Text] [PDF] Supplementary Data  

Eradication of Tumor Colonization and Invasion by a B Cell–Specific Immunotoxin in a Murine Model for Human Primary Intraocular Lymphoma

Zhuqing Li, Sankaranarayana P. Mahesh, De Fen Shen, Baoying Liu, Willie O. Siu, Frank S. Hwang, Qing-Chen Wang, Chi-Chao Chan, Ira Pastan, and Robert B. Nussenblatt
Cancer Res 2006 66: 10586-10593. [Abstract] [Full Text] [PDF] Supplementary Data  

Endocrinology:

Androgens Modulate Expression of Transcription Intermediary Factor 2, an Androgen Receptor Coactivator whose Expression Level Correlates with Early Biochemical Recurrence in Prostate Cancer

Irina U. Agoulnik, Ajula Vaid, Manjula Nakka, Misty Alvarado, William E. Bingman, III, Halime Erdem, Anna Frolov, Carolyn L. Smith, Gustavo E. Ayala, Michael M. Ittmann, and Nancy L. Weigel
Cancer Res 2006 66: 10594-10602. [Abstract] [Full Text] [PDF] Supplementary Data  

PRKAR1A Inactivation Leads to Increased Proliferation and Decreased Apoptosis in Human B Lymphocytes

Audrey J. Robinson-White, Wolfgang W. Leitner, Eiman Aleem, Philipp Kaldis, Ioannis Bossis, and Constantine A. Stratakis
Cancer Res 2006 66: 10603-10612. [Abstract] [Full Text] [PDF] Supplementary Data  

Short Hairpin RNA Knockdown of the Androgen Receptor Attenuates Ligand-Independent Activation and Delays Tumor Progression

Helen Cheng, Rob Snoek, Fariba Ghaidi, Michael E. Cox, and Paul S. Rennie
Cancer Res 2006 66: 10613-10620. [Abstract] [Full Text] [PDF]  

Epidemiology and Prevention:

Examination of a CpG Island Methylator Phenotype and Implications of Methylation Profiles in Solid Tumors

Carmen J. Marsit, E. Andres Houseman, Brock C. Christensen, Karen Eddy, Raphael Bueno, David J. Sugarbaker, Heather H. Nelson, Margaret R. Karagas, and Karl T. Kelsey
Cancer Res 2006 66: 10621-10629. [Abstract] [Full Text] [PDF]  

The Absolute Risk of Cervical Abnormalities in High-risk Human Papillomavirus–Positive, Cytologically Normal Women Over a 10-Year Period

Susanne Kjaer, Estrid Høgdall, Kirsten Frederiksen, Christian Munk, Adriaan van den Brule, Edith Svare, Chris Meijer, Attilla Lorincz, and Thomas Iftner
Cancer Res 2006 66: 10630-10636. [Abstract] [Full Text] [PDF]  

Correction:

Autoantibody ECPKA as a Cancer Biomarker

Cancer Res 2006 66: 10637. [Full Text] [PDF]  

To see an article, click its [Full Text] or [PDF] link. To review many abstracts, check the boxes to the left of the titles you want, and click the 'Get All Checked Abstract(s)' button. To see one abstract at a time, click its [Abstract] link.