On the Cover Inhibition of VEGF signaling can reduce the vascularity of tumors and leakiness of surviving vessels, but little is known about how these changes impact the delivery of therapeutic antibodies to tumors. Treatment with a potent inhibitor of VEGF signaling reduced the overall accumulation of extravasated antibodies, but the reduction was less than the decrease in vascularity, and antibody accumulation actually increased when expressed per surviving tumor vessel. The patchy pattern of extravasated antibodies coincided with sleeves of basement membrane left behind by regressing tumor vessels. Together, the findings suggest that tumor vessels normalized by inhibition of VEGF signaling provide more efficient delivery of antibodies, and basement membrane sleeves may facilitate antibody transport within tumors. The cover image illustrates that in Lewis lung carcinoma tumors under baseline conditions, leakage of antifibrin antibody was largely confined to the host-tumor interface; little was present elsewhere in the tumor. For details, see the article by Nakahara et al. on page 1434 of this issue.