Reviews:

Antiangiogenic Strategies on Defense: On the Possibility of Blocking Rebounds by the Tumor Vasculature after Chemotherapy

Yuval Shaked and Robert S. Kerbel
Cancer Res 2007 67: 7055-7058. doi: 10.1158/0008-5472.CAN-07-0905 [Abstract] [Full Text] [PDF]  

Tumor Angiogenesis: Cause or Consequence of Cancer?

Ksenya Shchors and Gerard Evan
Cancer Res 2007 67: 7059-7061. doi: 10.1158/0008-5472.CAN-07-2053 [Abstract] [Full Text] [PDF]  

Priority Reports:

Metastasis-Associated Protein 1 Transgenic Mice: A New Model of Spontaneous B-Cell Lymphomas

Rozita Bagheri-Yarmand, Seetharaman Balasenthil, Anupama E. Gururaj, Amjad H. Talukder, Yui-Hsi Wang, Ju Han Lee, Young Sik Kim, Xinaglan Zhang, Daniel M. Jones, L. Jeffrey Medeiros, L. Clifton Stephens, Yong-Jun Liu, Norman Lee, Insun Kim, and Rakesh Kumar
Cancer Res 2007 67: 7062-7067. doi: 10.1158/0008-5472.CAN-07-0748 [Abstract] [Full Text] [PDF] Supplementary Data  

Delayed Progression of Pancreatic Intraepithelial Neoplasia in a Conditional Kras^G12D Mouse Model by a Selective Cyclooxygenase-2 Inhibitor

Hitoshi Funahashi, Makoto Satake, David Dawson, Ngoc-An Huynh, Howard A. Reber, Oscar J. Hines, and Guido Eibl
Cancer Res 2007 67: 7068-7071. Published Online First July 24, 2007. doi: 10.1158/0008-5472.CAN-07-0970 [Abstract] [Full Text] [PDF]  

DNA Damage Induces Alternative Lengthening of Telomeres (ALT)–Associated Promyelocytic Leukemia Bodies that Preferentially Associate with Linear Telomeric DNA

Clare L. Fasching, Axel A. Neumann, Alessandra Muntoni, Thomas R. Yeager, and Roger R. Reddel
Cancer Res 2007 67: 7072-7077. Published Online First July 24, 2007. doi: 10.1158/0008-5472.CAN-07-1556 [Abstract] [Full Text] [PDF]  

BRCA1- and BRCA2-Deficient Cells Are Sensitive to Etoposide-Induced DNA Double-Strand Breaks via Topoisomerase II

Alejandro D. Treszezamsky, Lisa A. Kachnic, Zhihui Feng, Junran Zhang, Chake Tokadjian, and Simon N. Powell
Cancer Res 2007 67: 7078-7081. doi: 10.1158/0008-5472.CAN-07-0601 [Abstract] [Full Text] [PDF]  

Novel Tryptophan Catabolic Enzyme IDO2 Is the Preferred Biochemical Target of the Antitumor Indoleamine 2,3-Dioxygenase Inhibitory Compound D-1-Methyl-Tryptophan

Richard Metz, James B. DuHadaway, Uma Kamasani, Lisa Laury-Kleintop, Alexander J. Muller, and George C. Prendergast
Cancer Res 2007 67: 7082-7087. doi: 10.1158/0008-5472.CAN-07-1872 [Abstract] [Full Text] [PDF] Supplementary Data  

Molecular Biology, Pathobiology, and Genetics:

Exposure to the Tobacco Smoke Constituent 4-Aminobiphenyl Induces Chromosomal Instability in Human Cancer Cells

Federica Saletta, Giuseppe Matullo, Maurizio Manuguerra, Sabrina Arena, Alberto Bardelli, and Paolo Vineis
Cancer Res 2007 67: 7088-7094. doi: 10.1158/0008-5472.CAN-06-4420 [Abstract] [Full Text] [PDF]  

Promoter Hypermethylation Contributes to Frequent Inactivation of a Putative Conditional Tumor Suppressor Gene Connective Tissue Growth Factor in Ovarian Cancer

Ryoko Kikuchi, Hitoshi Tsuda, Yae Kanai, Takahiro Kasamatsu, Kazuo Sengoku, Setsuo Hirohashi, Johji Inazawa, and Issei Imoto
Cancer Res 2007 67: 7095-7105. doi: 10.1158/0008-5472.CAN-06-4567 [Abstract] [Full Text] [PDF] Supplementary Data  

Identification of S664 TSC2 Phosphorylation as a Marker for Extracellular Signal-Regulated Kinase–Mediated mTOR Activation in Tuberous Sclerosis and Human Cancer

Li Ma, Julie Teruya-Feldstein, Pauline Bonner, Rosa Bernardi, David Neal Franz, David Witte, Carlos Cordon-Cardo, and Pier Paolo Pandolfi
Cancer Res 2007 67: 7106-7112. doi: 10.1158/0008-5472.CAN-06-4798 [Abstract] [Full Text] [PDF]  

Profiling Microdissected Epithelium and Stroma to Model Genomic Signatures for Cervical Carcinogenesis Accommodating for Covariates

David Gius, Margo C. Funk, Eric Y. Chuang, Sheng Feng, Phyllis C. Huettner, Loan Nguyen, C. Matthew Bradbury, Mark Mishra, Shuping Gao, Barbara M. Buttin, David E. Cohn, Matthew A. Powell, Neil S. Horowitz, Bradford P. Whitcomb, and Janet S. Rader
Cancer Res 2007 67: 7113-7123. doi: 10.1158/0008-5472.CAN-07-0260 [Abstract] [Full Text] [PDF] Supplementary Data  

IFN-ß Signaling Positively Regulates Tumorigenesis in Aggressive Fibromatosis, Potentially by Modulating Mesenchymal Progenitors

Sean S. Tjandra, Claire Hsu, Ingrid Goh, Ananta Gurung, Raymond Poon, Puviindran Nadesan, and Benjamin A. Alman
Cancer Res 2007 67: 7124-7131. doi: 10.1158/0008-5472.CAN-07-0686 [Abstract] [Full Text] [PDF]  

Identification of Pax5 as a Target of MTA1 in B-Cell Lymphomas

Seetharaman Balasenthil, Anupama E. Gururaj, Amjad H. Talukder, Rozita Bagheri-Yarmand, Ty Arrington, Brian J. Haas, John C. Braisted, Insun Kim, Norman H. Lee, and Rakesh Kumar
Cancer Res 2007 67: 7132-7138. doi: 10.1158/0008-5472.CAN-07-0750 [Abstract] [Full Text] [PDF] Supplementary Data  

Oncogenic NRAS, KRAS, and HRAS Exhibit Different Leukemogenic Potentials in Mice

Chaitali Parikh, Ramesh Subrahmanyam, and Ruibao Ren
Cancer Res 2007 67: 7139-7146. doi: 10.1158/0008-5472.CAN-07-0778 [Abstract] [Full Text] [PDF]  

Haploinsufficiency of Krüppel-Like Factor 4 Promotes Adenomatous Polyposis Coli–Dependent Intestinal Tumorigenesis

Amr M. Ghaleb, Beth B. McConnell, Mandayam O. Nandan, Jonathan P. Katz, Klaus H. Kaestner, and Vincent W. Yang
Cancer Res 2007 67: 7147-7154. doi: 10.1158/0008-5472.CAN-07-1302 [Abstract] [Full Text] [PDF] Supplementary Data  

Cell, Tumor, and Stem Cell Biology:

p53 Activation in Response to Mitotic Spindle Damage Requires Signaling via BubR1-Mediated Phosphorylation

Geun-Hyoung Ha, Kwan-Hyuck Baek, Hyun-Soo Kim, Sook-Jung Jeong, Chang-Min Kim, Frank McKeon, and Chang-Woo Lee
Cancer Res 2007 67: 7155-7164. doi: 10.1158/0008-5472.CAN-06-3392 [Abstract] [Full Text] [PDF] Supplementary Data  

Tripeptidyl-peptidase II Controls DNA Damage Responses and In vivo -Irradiation Resistance of Tumors

Xu Hong, Lu Lei, Brita Künert, Rajender Naredla, Steven E. Applequist, Alf Grandien, and Rickard Glas
Cancer Res 2007 67: 7165-7174. doi: 10.1158/0008-5472.CAN-06-4094 [Abstract] [Full Text] [PDF] Supplementary Data  

An Improved Bioluminescence Resonance Energy Transfer Strategy for Imaging Intracellular Events in Single Cells and Living Subjects

Abhijit De, Andreas Markus Loening, and Sanjiv Sam Gambhir
Cancer Res 2007 67: 7175-7183. doi: 10.1158/0008-5472.CAN-06-4623 [Abstract] [Full Text] [PDF] Supplementary Data  

Krüppel-Like Factor 8 Induces Epithelial to Mesenchymal Transition and Epithelial Cell Invasion

Xianhui Wang, Mingzhe Zheng, Gang Liu, Weiya Xia, Paula J. McKeown-Longo, Mien-Chie Hung, and Jihe Zhao
Cancer Res 2007 67: 7184-7193. doi: 10.1158/0008-5472.CAN-06-4729 [Abstract] [Full Text] [PDF] Supplementary Data  

Enhanced Peritoneal Ovarian Tumor Dissemination by Tissue Transglutaminase

Minati Satpathy, Liyun Cao, Roxana Pincheira, Robert Emerson, Robert Bigsby, Harikrishna Nakshatri, and Daniela Matei
Cancer Res 2007 67: 7194-7202. doi: 10.1158/0008-5472.CAN-07-0307 [Abstract] [Full Text] [PDF] Supplementary Data  

ELMO1 and Dock180, a Bipartite Rac1 Guanine Nucleotide Exchange Factor, Promote Human Glioma Cell Invasion

Michael J. Jarzynka, Bo Hu, Kwok-Min Hui, Ifat Bar-Joseph, Weisong Gu, Takanori Hirose, Lisa B. Haney, Kodi S. Ravichandran, Ryo Nishikawa, and Shi-Yuan Cheng
Cancer Res 2007 67: 7203-7211. doi: 10.1158/0008-5472.CAN-07-0473 [Abstract] [Full Text] [PDF] Supplementary Data  

Overexpression of the Low Molecular Weight Cyclin E in Transgenic Mice Induces Metastatic Mammary Carcinomas through the Disruption of the ARF-p53 Pathway

Said Akli, Carolyn S. Van Pelt, Tuyen Bui, Asha S. Multani, Sandy Chang, David Johnson, Susan Tucker, and Khandan Keyomarsi
Cancer Res 2007 67: 7212-7222. doi: 10.1158/0008-5472.CAN-07-0599 [Abstract] [Full Text] [PDF] Supplementary Data  

Silencing of FLRG, an Antagonist of Activin, Inhibits Human Breast Tumor Cell Growth

Diane Razanajaona, Stéphanie Joguet, Anne-Sophie Ay, Isabelle Treilleux, Sophie Goddard-Léon, Laurent Bartholin, and Ruth Rimokh
Cancer Res 2007 67: 7223-7229. doi: 10.1158/0008-5472.CAN-07-0805 [Abstract] [Full Text] [PDF]  

Cannabinoid Modulation of Kaposi's Sarcoma–Associated Herpesvirus Infection and Transformation

Xuefeng Zhang, Jian Feng Wang, George Kunos, and Jerome E. Groopman
Cancer Res 2007 67: 7230-7237. doi: 10.1158/0008-5472.CAN-07-0960 [Abstract] [Full Text] [PDF]  

Nm23-H1 Suppresses Tumor Cell Motility by Down-regulating the Lysophosphatidic Acid Receptor EDG2

Christine E. Horak, Jong Heun Lee, Abdel G. Elkahloun, Mathieu Boissan, Sylvie Dumont, Tara K. Maga, Sandrine Arnaud-Dabernat, Diane Palmieri, William G. Stetler-Stevenson, Marie-Lise Lacombe, Paul S. Meltzer, and Patricia S. Steeg
Cancer Res 2007 67: 7238-7246. doi: 10.1158/0008-5472.CAN-07-0962 [Abstract] [Full Text] [PDF] Supplementary Data  

The Survival Kinase Mirk/Dyrk1B Is a Downstream Effector of Oncogenic K-ras in Pancreatic Cancer

Kideok Jin, Sunju Park, Daina Z. Ewton, and Eileen Friedman
Cancer Res 2007 67: 7247-7255. doi: 10.1158/0008-5472.CAN-06-4099 [Abstract] [Full Text] [PDF]  

Epidermal Growth Factor Receptor Tyrosine Phosphorylation and Signaling Controlled by a Nuclear Receptor Coactivator, Amplified in Breast Cancer 1

Tyler Lahusen, Mark Fereshteh, Annabell Oh, Anton Wellstein, and Anna T. Riegel
Cancer Res 2007 67: 7256-7265. doi: 10.1158/0008-5472.CAN-07-1013 [Abstract] [Full Text] [PDF] Supplementary Data  

Antiapoptotic Effects of Progastrin on Pancreatic Cancer Cells Are Mediated by Sustained Activation of Nuclear Factor-B

William Rengifo-Cam, Shahid Umar, Shubhashish Sarkar, and Pomila Singh
Cancer Res 2007 67: 7266-7274. doi: 10.1158/0008-5472.CAN-07-1206 [Abstract] [Full Text] [PDF] Supplementary Data  

Experimental Therapeutics, Molecular Targets, and Chemical Biology:

Interaction of MLL Amino Terminal Sequences with Menin Is Required for Transformation

Corrado Caslini, Zhaohai Yang, Mohamad El-Osta, Thomas A. Milne, Robert K. Slany, and Jay L. Hess
Cancer Res 2007 67: 7275-7283. doi: 10.1158/0008-5472.CAN-06-2369 [Abstract] [Full Text] [PDF] Supplementary Data  

Lysis of Dysplastic but not Normal Oral Keratinocytes and Tissue-Engineered Epithelia with Conditionally Replicating Adenoviruses

Kamis Gaballah, Allison Hills, David Curiel, Gunnel Hallden, Paul Harrison, and Max Partridge
Cancer Res 2007 67: 7284-7294. doi: 10.1158/0008-5472.CAN-06-3834 [Abstract] [Full Text] [PDF]  

Targeting Matrix Metalloproteinases and Endothelial Cells with a Fusion Peptide against Tumor

Yufei Zou, Yahui Chen, Yongqiang Jiang, Jin Gao, and Jun Gu
Cancer Res 2007 67: 7295-7300. doi: 10.1158/0008-5472.CAN-06-3920 [Abstract] [Full Text] [PDF]  

Protection of Zinc against Tumor Necrosis Factor–Induced Lethal Inflammation Depends on Heat Shock Protein 70 and Allows Safe Antitumor Therapy

Wim Van Molle, Maarten Van Roy, Tom Van Bogaert, Lien Dejager, Philippe Van Lint, Ineke Vanlaere, Kenji Sekikawa, George Kollias, and Claude Libert
Cancer Res 2007 67: 7301-7307. doi: 10.1158/0008-5472.CAN-06-4010 [Abstract] [Full Text] [PDF]  

Therapeutic Relevance of Osteoprotegerin Gene Therapy in Osteosarcoma: Blockade of the Vicious Cycle between Tumor Cell Proliferation and Bone Resorption

Franois Lamoureux, Peggy Richard, Yohann Wittrant, Séverine Battaglia, Paul Pilet, Valérie Trichet, Frédéric Blanchard, Franois Gouin, Bruno Pitard, Dominique Heymann, and Franoise Redini
Cancer Res 2007 67: 7308-7318. doi: 10.1158/0008-5472.CAN-06-4130 [Abstract] [Full Text] [PDF]  

Oncogenic Activity of Epidermal Growth Factor Receptor Kinase Mutant Alleles Is Enhanced by the T790M Drug Resistance Mutation

Nadia Godin-Heymann, Ianthe Bryant, Miguel N. Rivera, Lindsey Ulkus, Daphne W. Bell, David J. Riese, II, Jeffrey Settleman, and Daniel A. Haber
Cancer Res 2007 67: 7319-7326. doi: 10.1158/0008-5472.CAN-06-4625 [Abstract] [Full Text] [PDF] Supplementary Data  

A Human scFv Antibody against TRAIL Receptor 2 Induces Autophagic Cell Death in Both TRAIL-Sensitive and TRAIL-Resistant Cancer Cells

Kyung-Jin Park, Seung-Hyun Lee, Tae-In Kim, Hae-Won Lee, Chang-Han Lee, Eun-Hee Kim, Ji-Young Jang, Kyeong Sook Choi, Myung-Hee Kwon, and Yong-Sung Kim
Cancer Res 2007 67: 7327-7334. doi: 10.1158/0008-5472.CAN-06-4766 [Abstract] [Full Text] [PDF] Supplementary Data  

Visualizing the Dynamics of EGFR Activity and Antiglioma Therapies In vivo

Esther Arwert, Shawn Hingtgen, Jose-Luiz Figueiredo, Henry Bergquist, Umar Mahmood, Ralph Weissleder, and Khalid Shah
Cancer Res 2007 67: 7335-7342. doi: 10.1158/0008-5472.CAN-07-0077 [Abstract] [Full Text] [PDF] Supplementary Data  

Monoclonal Antibody Blockade of the Human Eag1 Potassium Channel Function Exerts Antitumor Activity

David Gómez-Varela, Esther Zwick-Wallasch, Hendrik Knötgen, Araceli Sánchez, Thore Hettmann, Dmitri Ossipov, Rüdiger Weseloh, Constanza Contreras-Jurado, Mike Rothe, Walter Stühmer, and Luis A. Pardo
Cancer Res 2007 67: 7343-7349. doi: 10.1158/0008-5472.CAN-07-0107 [Abstract] [Full Text] [PDF]  

Induction of p53-Dependent Senescence by the MDM2 Antagonist Nutlin-3a in Mouse Cells of Fibroblast Origin

Alejo Efeyan, Ana Ortega-Molina, Susana Velasco-Miguel, Daniel Herranz, Lyubomir T. Vassilev, and Manuel Serrano
Cancer Res 2007 67: 7350-7357. doi: 10.1158/0008-5472.CAN-07-0200 [Abstract] [Full Text] [PDF] Supplementary Data  

Sequential Loss of Tumor Vessel Pericytes and Endothelial Cells after Inhibition of Platelet-Derived Growth Factor B by Selective Aptamer AX102

Barbara Sennino, Beverly L. Falcón, Dilara McCauley, Tom Le, Thomas McCauley, Jeffrey C. Kurz, Amy Haskell, David M. Epstein, and Donald M. McDonald
Cancer Res 2007 67: 7358-7367. doi: 10.1158/0008-5472.CAN-07-0293 [Abstract] [Full Text] [PDF] Supplementary DataSupplementary Data  

Dual Role of Mitochondrial Reactive Oxygen Species in Hypoxia Signaling: Activation of Nuclear Factor-B via c-SRC– and Oxidant-Dependent Cell Death

Josep M. Lluis, Francesca Buricchi, Paola Chiarugi, Albert Morales, and José C. Fernandez-Checa
Cancer Res 2007 67: 7368-7377. doi: 10.1158/0008-5472.CAN-07-0515 [Abstract] [Full Text] [PDF] Supplementary Data  

Inhibition of Cysteine Cathepsin Protease Activity Enhances Chemotherapy Regimens by Decreasing Tumor Growth and Invasiveness in a Mouse Model of Multistage Cancer

Katherine M. Bell-McGuinn, Alfred L. Garfall, Matthew Bogyo, Douglas Hanahan, and Johanna A. Joyce
Cancer Res 2007 67: 7378-7385. doi: 10.1158/0008-5472.CAN-07-0602 [Abstract] [Full Text] [PDF]  

Statin-Induced Breast Cancer Cell Death: Role of Inducible Nitric Oxide and Arginase-Dependent Pathways

Srigiridhar Kotamraju, Carol L. Willams, and Balaraman Kalyanaraman
Cancer Res 2007 67: 7386-7394. doi: 10.1158/0008-5472.CAN-07-0993 [Abstract] [Full Text] [PDF] Supplementary Data  

Proteasome Function Is Required for DNA Damage Response and Fanconi Anemia Pathway Activation

Céline Jacquemont and Toshiyasu Taniguchi
Cancer Res 2007 67: 7395-7405. doi: 10.1158/0008-5472.CAN-07-1015 [Abstract] [Full Text] [PDF] Supplementary Data  

Isoobtusilactone A Induces Cell Cycle Arrest and Apoptosis through Reactive Oxygen Species/Apoptosis Signal-Regulating Kinase 1 Signaling Pathway in Human Breast Cancer Cells

Po-Lin Kuo, Chung-Yi Chen, and Ya-Ling Hsu
Cancer Res 2007 67: 7406-7420. doi: 10.1158/0008-5472.CAN-07-1089 [Abstract] [Full Text] [PDF]  

Combined Yeast ß-Glucan and Antitumor Monoclonal Antibody Therapy Requires C5a-Mediated Neutrophil Chemotaxis via Regulation of Decay-Accelerating Factor CD55

Bing Li, Daniel J. Allendorf, Richard Hansen, Jose Marroquin, Daniel E. Cramer, Claire L. Harris, and Jun Yan
Cancer Res 2007 67: 7421-7430. doi: 10.1158/0008-5472.CAN-07-1465 [Abstract] [Full Text] [PDF]  

Clinical Validity of the Lung Cancer Biomarkers Identified by Bioinformatics Analysis of Public Expression Data

Bumjin Kim, Hyun Joo Lee, Hye Young Choi, Youngah Shin, Seungyoon Nam, Gilju Seo, Dae-Soon Son, Jisuk Jo, Jaesang Kim, Jinseon Lee, Jhingook Kim, Kwhanmien Kim, and Sanghyuk Lee
Cancer Res 2007 67: 7431-7438. doi: 10.1158/0008-5472.CAN-07-0003 [Abstract] [Full Text] [PDF] Supplementary Data  

Guggulsterone-Induced Apoptosis in Human Prostate Cancer Cells Is Caused by Reactive Oxygen Intermediate–Dependent Activation of c-Jun NH₂-Terminal Kinase

Shivendra V. Singh, Sunga Choi, Yan Zeng, Eun-Ryeong Hahm, and Dong Xiao
Cancer Res 2007 67: 7439-7449. doi: 10.1158/0008-5472.CAN-07-0120 [Abstract] [Full Text] [PDF]  

Immunology:

Targeting Human T Cells with Zoledronate and Interleukin-2 for Immunotherapy of Hormone-Refractory Prostate Cancer

Francesco Dieli, David Vermijlen, Fabio Fulfaro, Nadia Caccamo, Serena Meraviglia, Giuseppe Cicero, Andrew Roberts, Simona Buccheri, Matilde D'Asaro, Nicola Gebbia, Alfredo Salerno, Matthias Eberl, and Adrian C. Hayday
Cancer Res 2007 67: 7450-7457. doi: 10.1158/0008-5472.CAN-07-0199 [Abstract] [Full Text] [PDF] Supplementary Data  

Human Tumor-Derived Exosomes Selectively Impair Lymphocyte Responses to Interleukin-2

Aled Clayton, J. Paul Mitchell, Jacquelyn Court, Malcolm D. Mason, and Zsuzsanna Tabi
Cancer Res 2007 67: 7458-7466. doi: 10.1158/0008-5472.CAN-06-3456 [Abstract] [Full Text] [PDF] Supplementary Data  

Decreased Tumor Surveillance after Adoptive T-Cell Therapy

Matthias Matter, Viktor Pavelic, Daniel D. Pinschewer, Sabine Mumprecht, Bruno Eschli, Tsanan Giroglou, Dorothee von Laer, and Adrian F. Ochsenbein
Cancer Res 2007 67: 7467-7476. doi: 10.1158/0008-5472.CAN-06-4372 [Abstract] [Full Text] [PDF] Supplementary Data  

A Combination of Chemoimmunotherapies Can Efficiently Break Self-Tolerance and Induce Antitumor Immunity in a Tolerogenic Murine Tumor Model

Hyun-Jeong Ko, Yeon-Jeong Kim, Yun-Sun Kim, Woo-Sung Chang, Sung-Youl Ko, Sun-Young Chang, Shimon Sakaguchi, and Chang-Yuil Kang
Cancer Res 2007 67: 7477-7486. doi: 10.1158/0008-5472.CAN-06-4639 [Abstract] [Full Text] [PDF] Supplementary Data  

Interleukin-2 Administration Alters the CD4⁺FOXP3⁺ T-Cell Pool and Tumor Trafficking in Patients with Ovarian Carcinoma

Shuang Wei, Ilona Kryczek, Robert P. Edwards, Linhua Zou, Wojciech Szeliga, Mousumi Banerjee, Marilyn Cost, Pui Cheng, Alfred Chang, Bruce Redman, Ronald B. Herberman, and Weiping Zou
Cancer Res 2007 67: 7487-7494. doi: 10.1158/0008-5472.CAN-07-0565 [Abstract] [Full Text] [PDF]  

Combined Natural Killer T-Cell–Based Immunotherapy Eradicates Established Tumors in Mice

Michele W.L. Teng, Jennifer A. Westwood, Phillip K. Darcy, Janelle Sharkey, Moriya Tsuji, Richard W. Franck, Steven A. Porcelli, Gurdyal S. Besra, Kazuyoshi Takeda, Hideo Yagita, Michael H. Kershaw, and Mark J. Smyth
Cancer Res 2007 67: 7495-7504. doi: 10.1158/0008-5472.CAN-07-0941 [Abstract] [Full Text] [PDF] Supplementary Data  

Endocrinology:

A Growth Hormone Receptor Mutation Impairs Growth Hormone Autofeedback Signaling in Pituitary Tumors

Sylvia L. Asa, Rebecca DiGiovanni, Jing Jiang, Megan L. Ward, Kimberly Loesch, Shozo Yamada, Toshiaki Sano, Katsuhiko Yoshimoto, Stuart J. Frank, and Shereen Ezzat
Cancer Res 2007 67: 7505-7511. doi: 10.1158/0008-5472.CAN-07-0219 [Abstract] [Full Text] [PDF] Supplementary Data  

Down-regulation of the Sodium/Iodide Symporter Explains ¹³¹I-Induced Thyroid Stunning

Madeleine M. Nordén, Fredrik Larsson, Sofia Tedelind, Therese Carlsson, Charlotta Lundh, Eva Forssell-Aronsson, and Mikael Nilsson
Cancer Res 2007 67: 7512-7517. doi: 10.1158/0008-5472.CAN-07-0823 [Abstract] [Full Text] [PDF]  

Clinical Research:

CXC Chemokine Receptor-4 Antagonist Blocks Both Growth of Primary Tumor and Metastasis of Head and Neck Cancer in Xenograft Mouse Models

Younghyoun Yoon, Zhongxing Liang, Xin Zhang, Mison Choe, Aizhi Zhu, Heidi T. Cho, Dong M. Shin, Mark M. Goodman, Zhuo (Georgia) Chen, and Hyunsuk Shim
Cancer Res 2007 67: 7518-7524. doi: 10.1158/0008-5472.CAN-06-2263 [Abstract] [Full Text] [PDF] Supplementary Data  

Mouse Models of Prostate Adenocarcinoma with the Capacity to Monitor Spontaneous Carcinogenesis by Bioluminescence or Fluorescence

Chun-Peng Liao, Chen Zhong, Gohar Saribekyan, James Bading, Ryan Park, Peter S. Conti, Rex Moats, Anton Berns, Wei Shi, Zongxiang Zhou, Alexander Yu Nikitin, and Pradip Roy-Burman
Cancer Res 2007 67: 7525-7533. doi: 10.1158/0008-5472.CAN-07-0668 [Abstract] [Full Text] [PDF]  

Epidemiology and Prevention:

Estrogen Plus Progestin Use, Microsatellite Instability, and the Risk of Colorectal Cancer in Women

Polly A. Newcomb, Yingye Zheng, Victoria M. Chia, Libby M. Morimoto, V. Paul Doria-Rose, Allyson Templeton, Stephen N. Thibodeau, and John D. Potter
Cancer Res 2007 67: 7534-7539. doi: 10.1158/0008-5472.CAN-06-4275 [Abstract] [Full Text] [PDF]  

Environmental Tobacco Smoke and Bladder Cancer Risk in Never Smokers of Los Angeles County

Xuejuan Jiang, Jian-Min Yuan, Paul L. Skipper, Steven R. Tannenbaum, and Mimi C. Yu
Cancer Res 2007 67: 7540-7545. doi: 10.1158/0008-5472.CAN-07-0048 [Abstract] [Full Text] [PDF]  

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