Reviews:

Mixed Lineage Leukemia Translocations and a Leukemia Stem Cell Program

Joerg Faber and Scott A. Armstrong
Cancer Res 2007 67: 8425-8428. doi: 10.1158/0008-5472.CAN-07-0972 [Abstract] [Full Text] [PDF]  

Tie2-Expressing Monocytes and Tumor Angiogenesis: Regulation by Hypoxia and Angiopoietin-2

Claire E. Lewis, Michele De Palma, and Luigi Naldini
Cancer Res 2007 67: 8429-8432. doi: 10.1158/0008-5472.CAN-07-1684 [Abstract] [Full Text] [PDF]  

Priority Reports:

MicroRNA-34b and MicroRNA-34c Are Targets of p53 and Cooperate in Control of Cell Proliferation and Adhesion-Independent Growth

David C. Corney, Andrea Flesken-Nikitin, Andrew K. Godwin, Wei Wang, and Alexander Yu. Nikitin
Cancer Res 2007 67: 8433-8438. Published Online First September 6, 2007. doi: 10.1158/0008-5472.CAN-07-1585 [Abstract] [Full Text] [PDF] Supplementary Data  

TFAP2C Controls Hormone Response in Breast Cancer Cells through Multiple Pathways of Estrogen Signaling

George W. Woodfield, Annamarie D. Horan, Yizhen Chen, and Ronald J. Weigel
Cancer Res 2007 67: 8439-8443. doi: 10.1158/0008-5472.CAN-07-2293 [Abstract] [Full Text] [PDF] Supplementary Data  

The Requirement for DNAM-1, NKG2D, and NKp46 in the Natural Killer Cell-Mediated Killing of Myeloma Cells

Yasser M. El-Sherbiny, Josephine L. Meade, Tim D. Holmes, Dennis McGonagle, Sarah L. Mackie, Ann W. Morgan, Gordon Cook, Sylvia Feyler, Stephen J. Richards, Faith E. Davies, Gareth J. Morgan, and Graham P. Cook
Cancer Res 2007 67: 8444-8449. doi: 10.1158/0008-5472.CAN-06-4230 [Abstract] [Full Text] [PDF]  

Induction of Protective CTL Immunity against Peptide Transporter TAP-Deficient Tumors through Dendritic Cell Vaccination

Benedict Chambers, Per Grufman, Vanoohi Fredriksson, Kenth Andersson, Marjet Roseboom, Sandra Laban, Marcel Camps, Elisabeth Z. Wolpert, Emmanuel J.H.J. Wiertz, Rienk Offringa, Hans-Gustaf Ljunggren, and Thorbald van Hall
Cancer Res 2007 67: 8450-8455. doi: 10.1158/0008-5472.CAN-07-1092 [Abstract] [Full Text] [PDF]  

SV40 Multiple Tissue Infection and Asbestos Exposure in a Hyperendemic Area for Malignant Mesothelioma

Manola Comar, Clara Rizzardi, Renata de Zotti, Mauro Melato, Massimo Bovenzi, Janet S. Butel, and Cesare Campello
Cancer Res 2007 67: 8456-8459. doi: 10.1158/0008-5472.CAN-07-2232 [Abstract] [Full Text] [PDF]  

Molecular Biology, Pathobiology, and Genetics:

Knock-in of Mutant K-ras in Nontumorigenic Human Epithelial Cells as a New Model for Studying K-ras–Mediated Transformation

Hiroyuki Konishi, Bedri Karakas, Abde M. Abukhdeir, Josh Lauring, John P. Gustin, Joseph P. Garay, Yuko Konishi, Eike Gallmeier, Kurtis E. Bachman, and Ben Ho Park
Cancer Res 2007 67: 8460-8467. doi: 10.1158/0008-5472.CAN-07-0108 [Abstract] [Full Text] [PDF] Supplementary Data  

Knock-in of Oncogenic Kras Does Not Transform Mouse Somatic Cells But Triggers a Transcriptional Response that Classifies Human Cancers

Sabrina Arena, Claudio Isella, Miriam Martini, Ario de Marco, Enzo Medico, and Alberto Bardelli
Cancer Res 2007 67: 8468-8476. doi: 10.1158/0008-5472.CAN-07-1126 [Abstract] [Full Text] [PDF] Supplementary Data  

Histone Deacetylase Inhibitors Induce Cell Death Selectively in Cells That Harbor Activated kRasV12: The Role of Signal Transducers and Activators of Transcription 1 and p21

Lidija Klampfer, Jie Huang, Senji Shirasawa, Takehiko Sasazuki, and Leonard Augenlicht
Cancer Res 2007 67: 8477-8485. doi: 10.1158/0008-5472.CAN-07-0210 [Abstract] [Full Text] [PDF] Supplementary Data  

Membrane-Bound Heparin-Binding Epidermal Growth Factor–Like Growth Factor Regulates E-Cadherin Expression in Pancreatic Carcinoma Cells

Fang Wang, Callum Sloss, Xiaobo Zhang, Sam W. Lee, and James C. Cusack
Cancer Res 2007 67: 8486-8493. doi: 10.1158/0008-5472.CAN-07-0498 [Abstract] [Full Text] [PDF]  

Activation of the Signal Transducers and Activators of the Transcription 3 Pathway in Alveolar Epithelial Cells Induces Inflammation and Adenocarcinomas in Mouse Lung

Yuan Li, Hong Du, Yulin Qin, Jennifer Roberts, Oscar W. Cummings, and Cong Yan
Cancer Res 2007 67: 8494-8503. doi: 10.1158/0008-5472.CAN-07-0647 [Abstract] [Full Text] [PDF] Supplementary Data  

Genomic Profiling Reveals Alternative Genetic Pathways of Prostate Tumorigenesis

Jacques Lapointe, Chunde Li, Craig P. Giacomini, Keyan Salari, Stephanie Huang, Pei Wang, Michelle Ferrari, Tina Hernandez-Boussard, James D. Brooks, and Jonathan R. Pollack
Cancer Res 2007 67: 8504-8510. doi: 10.1158/0008-5472.CAN-07-0673 [Abstract] [Full Text] [PDF] Supplementary Data  

Ultradeep Bisulfite Sequencing Analysis of DNA Methylation Patterns in Multiple Gene Promoters by 454 Sequencing

Kristen H. Taylor, Robin S. Kramer, J. Wade Davis, Juyuan Guo, Deiter J. Duff, Dong Xu, Charles W. Caldwell, and Huidong Shi
Cancer Res 2007 67: 8511-8518. doi: 10.1158/0008-5472.CAN-07-1016 [Abstract] [Full Text] [PDF] Supplementary Data  

Differential Expression and Function of Caveolin-1 in Human Gastric Cancer Progression

Elke Burgermeister, Xiangbin Xing, Christoph Röcken, Mark Juhasz, Jie Chen, Michaela Hiber, Katrin Mair, Maria Shatz, Moti Liscovitch, Roland M. Schmid, and Matthias P.A. Ebert
Cancer Res 2007 67: 8519-8526. doi: 10.1158/0008-5472.CAN-07-1125 [Abstract] [Full Text] [PDF] Supplementary Data  

Functional Interplay of p53 and Mus81 in DNA Damage Responses and Cancer

Ashwin Pamidi, Renato Cardoso, Anne Hakem, Elzbieta Matysiak-Zablocki, Anuradha Poonepalli, Laura Tamblyn, Bayardo Perez-Ordonez, M. Prakash Hande, Otto Sanchez, and Razqallah Hakem
Cancer Res 2007 67: 8527-8535. doi: 10.1158/0008-5472.CAN-07-1161 [Abstract] [Full Text] [PDF] Supplementary Data  

Inhibitors of the Proteasome Suppress Homologous DNA Recombination in Mammalian Cells

Yasuhiro Murakawa, Eiichiro Sonoda, Louise J. Barber, Weihua Zeng, Kyoko Yokomori, Hiroshi Kimura, Atsuko Niimi, Alan Lehmann, Guang Yu Zhao, Helfrid Hochegger, Simon J. Boulton, and Shunichi Takeda
Cancer Res 2007 67: 8536-8543. doi: 10.1158/0008-5472.CAN-07-1166 [Abstract] [Full Text] [PDF] Supplementary Data  

Activation of Holliday Junction–Recognizing Protein Involved in the Chromosomal Stability and Immortality of Cancer Cells

Tatsuya Kato, Nagato Sato, Satoshi Hayama, Takumi Yamabuki, Tomoo Ito, Masaki Miyamoto, Satoshi Kondo, Yusuke Nakamura, and Yataro Daigo
Cancer Res 2007 67: 8544-8553. Published Online First September 6, 2007. doi: 10.1158/0008-5472.CAN-07-1307 [Abstract] [Full Text] [PDF] Supplementary Data  

High SEPT9_v1 Expression in Human Breast Cancer Cells Is Associated with Oncogenic Phenotypes

Maria E. Gonzalez, Esther A. Peterson, Lisa M. Privette, Janice L. Loffreda-Wren, Linda M. Kalikin, and Elizabeth M. Petty
Cancer Res 2007 67: 8554-8564. doi: 10.1158/0008-5472.CAN-07-1474 [Abstract] [Full Text] [PDF] Supplementary Data  

Deletion of the AU-Rich RNA Binding Protein Apobec-1 Reduces Intestinal Tumor Burden in Apc^min Mice

Valerie Blanc, Jeffrey O. Henderson, Rodney D. Newberry, Yan Xie, Soo-Jin Cho, Elizabeth P. Newberry, Susan Kennedy, Deborah C. Rubin, Hanlin L. Wang, Jianyang Luo, and Nicholas O. Davidson
Cancer Res 2007 67: 8565-8573. doi: 10.1158/0008-5472.CAN-07-1593 [Abstract] [Full Text] [PDF] Supplementary Data  

Nitric Oxide Radicals Choreograph a Radioadaptive Response

Hideki Matsumoto, Akihisa Takahashi, and Takeo Ohnishi
Cancer Res 2007 67: 8574-8579. doi: 10.1158/0008-5472.CAN-07-1913 [Abstract] [Full Text] [PDF]  

In Non-neoplastic Barrett's Epithelial Cells, Acid Exerts Early Antiproliferative Effects through Activation of the Chk2 Pathway

Hui-Ying Zhang, Xi Zhang, Kathy Hormi-Carver, Linda A. Feagins, Stuart J. Spechler, and Rhonda F. Souza
Cancer Res 2007 67: 8580-8587. doi: 10.1158/0008-5472.CAN-07-2023 [Abstract] [Full Text] [PDF]  

Cell, Tumor, and Stem Cell Biology:

Spatiotemporal Differences in CXCL12 Expression and Cyclic AMP Underlie the Unique Pattern of Optic Glioma Growth in Neurofibromatosis Type 1

Nicole M. Warrington, B. Mark Woerner, Girish C. Daginakatte, Biplab Dasgupta, Arie Perry, David H. Gutmann, and Joshua B. Rubin
Cancer Res 2007 67: 8588-8595. doi: 10.1158/0008-5472.CAN-06-2220 [Abstract] [Full Text] [PDF] Supplementary DataSupplementary Data  

The Nuclear Matrix Protein, NRP/B, Enhances Nrf2-Mediated Oxidative Stress Responses in Breast Cancer Cells

Seyha Seng, Hava Karsenty Avraham, Shuxian Jiang, Suping Yang, Masayuki Sekine, Noam Kimelman, Huchun Li, and Shalom Avraham
Cancer Res 2007 67: 8596-8604. doi: 10.1158/0008-5472.CAN-06-3785 [Abstract] [Full Text] [PDF] Supplementary Data  

Differential Regulation of Hypoxia-Induced CXCR4 Triggering during B-Cell Development and Lymphomagenesis

Erich Piovan, Valeria Tosello, Stefano Indraccolo, Massimo Masiero, Luca Persano, Giovanni Esposito, Rita Zamarchi, Maurilio Ponzoni, Luigi Chieco-Bianchi, Riccardo Dalla-Favera, and Alberto Amadori
Cancer Res 2007 67: 8605-8614. doi: 10.1158/0008-5472.CAN-06-4722 [Abstract] [Full Text] [PDF] Supplementary Data  

Tissue Inhibitor of Metalloproteinases-1 Promotes Liver Metastasis by Induction of Hepatocyte Growth Factor Signaling

Charlotte Kopitz, Michael Gerg, Obul Reddy Bandapalli, Dilek Ister, Caroline J. Pennington, Stephanie Hauser, Christin Flechsig, Hans-Willi Krell, Dalibor Antolovic, Keith Brew, Hideaki Nagase, Manfred Stangl, Claus W. Hann von Weyhern, Björn L.D.M. Brücher, Karsten Brand, Lisa M. Coussens, Dylan R. Edwards, and Achim Krüger
Cancer Res 2007 67: 8615-8623. doi: 10.1158/0008-5472.CAN-07-0232 [Abstract] [Full Text] [PDF] Supplementary Data  

The Role of Platelet/Endothelial Cell Adhesion Molecule–1 (CD31) and CD38 Antigens in Marrow Microenvironmental Retention of Acute Myelogenous Leukemia Cells

Nathalie Gallay, Ludovic Anani, Adriana Lopez, Philippe Colombat, Christian Binet, Jorge Domenech, Babette B. Weksler, Fabio Malavasi, and Olivier Herault
Cancer Res 2007 67: 8624-8632. doi: 10.1158/0008-5472.CAN-07-0402 [Abstract] [Full Text] [PDF]  

The Role of S100P in the Invasion of Pancreatic Cancer Cells Is Mediated through Cytoskeletal Changes and Regulation of Cathepsin D

Hannah J. Whiteman, Mark E. Weeks, Sally E. Dowen, Sayka Barry, John F. Timms, Nicholas R. Lemoine, and Tatjana Crnogorac-Jurcevic
Cancer Res 2007 67: 8633-8642. doi: 10.1158/0008-5472.CAN-07-0545 [Abstract] [Full Text] [PDF] Supplementary Data  

Transforming Growth Factor-ß Can Suppress Tumorigenesis through Effects on the Putative Cancer Stem or Early Progenitor Cell and Committed Progeny in a Breast Cancer Xenograft Model

Binwu Tang, Naomi Yoo, Mary Vu, Mizuko Mamura, Jeong-Seok Nam, Akira Ooshima, Zhijun Du, Pierre-Yves Desprez, Miriam R. Anver, Aleksandra M. Michalowska, Joanna Shih, W. Tony Parks, and Lalage M. Wakefield
Cancer Res 2007 67: 8643-8652. doi: 10.1158/0008-5472.CAN-07-0982 [Abstract] [Full Text] [PDF] Supplementary Data  

A Novel Nonobese Diabetic/Severe Combined Immunodeficient Xenograft Model for Chronic Lymphocytic Leukemia Reflects Important Clinical Characteristics of the Disease

Jan Dürig, Peter Ebeling, Florian Grabellus, Ursula R. Sorg, Michael Möllmann, Philipp Schütt, Joachim Göthert, Ludger Sellmann, Siegfried Seeber, Michael Flasshove, Ulrich Dührsen, and Thomas Moritz
Cancer Res 2007 67: 8653-8661. doi: 10.1158/0008-5472.CAN-07-1198 [Abstract] [Full Text] [PDF] Supplementary Data  

Ionizing Radiation Predisposes Nonmalignant Human Mammary Epithelial Cells to Undergo Transforming Growth Factor ß–Induced Epithelial to Mesenchymal Transition

Kumari L. Andarawewa, Anna C. Erickson, William S. Chou, Sylvain V. Costes, Philippe Gascard, Joni D. Mott, Mina J. Bissell, and Mary Helen Barcellos-Hoff
Cancer Res 2007 67: 8662-8670. doi: 10.1158/0008-5472.CAN-07-1294 [Abstract] [Full Text] [PDF] Supplementary Data  

Identification of Tumorsphere- and Tumor-Initiating Cells in HER2/Neu-Induced Mammary Tumors

Jeff C. Liu, Tao Deng, Rajwinder S. Lehal, Jinny Kim, and Eldad Zacksenhaus
Cancer Res 2007 67: 8671-8681. doi: 10.1158/0008-5472.CAN-07-1486 [Abstract] [Full Text] [PDF]  

Regulation of Phosphoglucose Isomerase/Autocrine Motility Factor Activities by the Poly(ADP-Ribose) Polymerase Family-14

Takashi Yanagawa, Tatsuyoshi Funasaka, Soichi Tsutsumi, Huankai Hu, Hideomi Watanabe, and Avraham Raz
Cancer Res 2007 67: 8682-8689. doi: 10.1158/0008-5472.CAN-07-1586 [Abstract] [Full Text] [PDF] Supplementary Data  

Mastermind-like 1 Is a Specific Coactivator of ß-Catenin Transcription Activation and Is Essential for Colon Carcinoma Cell Survival

Marie-Clotilde Alves-Guerra, Chiara Ronchini, and Anthony J. Capobianco
Cancer Res 2007 67: 8690-8698. doi: 10.1158/0008-5472.CAN-07-1720 [Abstract] [Full Text] [PDF]  

MicroRNA Signatures in Human Ovarian Cancer

Marilena V. Iorio, Rosa Visone, Gianpiero Di Leva, Valentina Donati, Fabio Petrocca, Patrizia Casalini, Cristian Taccioli, Stefano Volinia, Chang-Gong Liu, Hansjuerg Alder, George A. Calin, Sylvie Ménard, and Carlo M. Croce
Cancer Res 2007 67: 8699-8707. doi: 10.1158/0008-5472.CAN-07-1936 [Abstract] [Full Text] [PDF] Supplementary Data  

Semaphorin SEMA3F Affects Multiple Signaling Pathways in Lung Cancer Cells

Vincent A. Potiron, Girish Sharma, Patrick Nasarre, Jonathan A. Clarhaut, Hellmut G. Augustin, Robert M. Gemmill, Joëlle Roche, and Harry A. Drabkin
Cancer Res 2007 67: 8708-8715. doi: 10.1158/0008-5472.CAN-06-3612 [Abstract] [Full Text] [PDF] Supplementary Data  

Degradation of HER2 by Cbl-Based Chimeric Ubiquitin Ligases

Xia Li, Liangliang Shen, Jing Zhang, Jin Su, Lan Shen, Xinping Liu, Hua Han, Wei Han, and Libo Yao
Cancer Res 2007 67: 8716-8724. doi: 10.1158/0008-5472.CAN-06-3731 [Abstract] [Full Text] [PDF]  

Nuclear Factor of Activated T3 Is a Negative Regulator of Ras-JNK1/2-AP-1–Induced Cell Transformation

Ke Yao, Yong-Yeon Cho, H. Robert Bergen, III, Benjamin J. Madden, Bu Young Choi, Wei-Ya Ma, Ann M. Bode, and Zigang Dong
Cancer Res 2007 67: 8725-8735. doi: 10.1158/0008-5472.CAN-06-4788 [Abstract] [Full Text] [PDF] Supplementary Data  

Repression of Vascular Endothelial Growth Factor Expression by the Zinc Finger Transcription Factor ZNF24

Jay Harper, Li Yan, Robyn M. Loureiro, Iinmin Wu, Jianmin Fang, Patricia A. D'Amore, and Marsha A. Moses
Cancer Res 2007 67: 8736-8741. doi: 10.1158/0008-5472.CAN-07-1617 [Abstract] [Full Text] [PDF]  

Experimental Therapeutics, Molecular Targets, and Chemical Biology:

Bone Morphogenetic Protein 7 in the Development and Treatment of Bone Metastases from Breast Cancer

Jeroen T. Buijs, Nico V. Henriquez, Petra G.M. van Overveld, Geertje van der Horst, Ivo Que, Ruth Schwaninger, Cyrill Rentsch, Peter ten Dijke, Anne-Marie Cleton-Jansen, Keltouma Driouch, Rosette Lidereau, Richard Bachelier, Slobodan Vukicevic, Philippe Clézardin, Socrates E. Papapoulos, Marco G. Cecchini, Clemens W.G.M. Löwik, and Gabri van der Pluijm
Cancer Res 2007 67: 8742-8751. doi: 10.1158/0008-5472.CAN-06-2490 [Abstract] [Full Text] [PDF] Supplementary Data  

Nonclassic Functions of Human Topoisomerase I: Genome-Wide and Pharmacologic Analyses

Ze-Hong Miao, Audrey Player, Uma Shankavaram, Yong-Hong Wang, Drazen B. Zimonjic, Philip L. Lorenzi, Zhi-Yong Liao, Hong Liu, Tsutomu Shimura, Hong-Liang Zhang, Ling-Hua Meng, Yong-Wei Zhang, Ernest S. Kawasaki, Nicholas C. Popescu, Mirit I. Aladjem, David J. Goldstein, John N. Weinstein, and Yves Pommier
Cancer Res 2007 67: 8752-8761. doi: 10.1158/0008-5472.CAN-06-4554 [Abstract] [Full Text] [PDF] Supplementary Data  

Reactive Oxygen Species, DNA Damage, and Error-Prone Repair: A Model for Genomic Instability with Progression in Myeloid Leukemia?

Feyruz V. Rassool, Terry J. Gaymes, Nader Omidvar, Nicola Brady, Stephanie Beurlet, Marika Pla, Murielle Reboul, Nicholas Lea, Christine Chomienne, Nicholas S.B. Thomas, Ghulam J. Mufti, and Rose Ann Padua
Cancer Res 2007 67: 8762-8771. doi: 10.1158/0008-5472.CAN-06-4807 [Abstract] [Full Text] [PDF] Supplementary Data  

Identification and Characterization of Genetic Variation in the Folylpolyglutamate Synthase Gene

Tarek A. Leil, Chiaki Endo, Araba A. Adjei, Grace K. Dy, Oreste E. Salavaggione, Joel R. Reid, Matthew M. Ames, and Alex A. Adjei
Cancer Res 2007 67: 8772-8782. doi: 10.1158/0008-5472.CAN-07-0156 [Abstract] [Full Text] [PDF] Supplementary Data  

A Capsid-Modified, Conditionally Replicating Oncolytic Adenovirus Vector Expressing TRAIL Leads to Enhanced Cancer Cell Killing in Human Glioblastoma Models

Martin E. Wohlfahrt, Brian C. Beard, André Lieber, and Hans-Peter Kiem
Cancer Res 2007 67: 8783-8790. doi: 10.1158/0008-5472.CAN-07-0357 [Abstract] [Full Text] [PDF]  

Identification and Biological Evaluation of a Novel and Potent Small Molecule Radiation Sensitizer via an Unbiased Screen of a Chemical Library

Brian E. Lally, Geoffrey A. Geiger, Steven Kridel, Alice E. Arcury-Quandt, Michael E. Robbins, Nancy D. Kock, Kenneth Wheeler, Prakash Peddi, Alexandros Georgakilas, Gary D. Kao, and Constantinos Koumenis
Cancer Res 2007 67: 8791-8799. doi: 10.1158/0008-5472.CAN-07-0477 [Abstract] [Full Text] [PDF]  

Lupeol Suppresses Cisplatin-Induced Nuclear Factor-B Activation in Head and Neck Squamous Cell Carcinoma and Inhibits Local Invasion and Nodal Metastasis in an Orthotopic Nude Mouse Model

Terence K. Lee, Ronnie T.P. Poon, Jana Y. Wo, Stephanie Ma, Xin-Yuan Guan, Jeffrey N. Myers, Peter Altevogt, and Anthony P.W. Yuen
Cancer Res 2007 67: 8800-8809. doi: 10.1158/0008-5472.CAN-07-0801 [Abstract] [Full Text] [PDF] Supplementary Data  

Efficient p53 Activation and Apoptosis by Simultaneous Disruption of Binding to MDM2 and MDMX

Baoli Hu, Daniele M. Gilkes, and Jiandong Chen
Cancer Res 2007 67: 8810-8817. doi: 10.1158/0008-5472.CAN-07-1140 [Abstract] [Full Text] [PDF]  

Targeting Human Medulloblastoma: Oncolytic Virotherapy with Myxoma Virus Is Enhanced by Rapamycin

Xue Qing Lun, Hongyuan Zhou, Tommy Alain, Beichen Sun, Limei Wang, John W. Barrett, Marianne M. Stanford, Grant McFadden, John Bell, Donna L. Senger, and Peter A. Forsyth
Cancer Res 2007 67: 8818-8827. doi: 10.1158/0008-5472.CAN-07-1214 [Abstract] [Full Text] [PDF] Supplementary Data  

Protein Kinase C Interacts with Signal Transducers and Activators of Transcription 3 (Stat3), Phosphorylates Stat3Ser727, and Regulates Its Constitutive Activation in Prostate Cancer

Moammir H. Aziz, Herbert T. Manoharan, Dawn R. Church, Nancy E. Dreckschmidt, Weixiong Zhong, Terry D. Oberley, George Wilding, and Ajit K. Verma
Cancer Res 2007 67: 8828-8838. doi: 10.1158/0008-5472.CAN-07-1604 [Abstract] [Full Text] [PDF]  

Topoisomerase IIß–Mediated DNA Double-Strand Breaks: Implications in Doxorubicin Cardiotoxicity and Prevention by Dexrazoxane

Yi Lisa Lyu, John E. Kerrigan, Chao-Po Lin, Anna M. Azarova, Yuan-Chin Tsai, Yi Ban, and Leroy F. Liu
Cancer Res 2007 67: 8839-8846. doi: 10.1158/0008-5472.CAN-07-1649 [Abstract] [Full Text] [PDF]  

Eradication of Large Tumors in Mice by a Tritherapy Targeting the Innate, Adaptive, and Regulatory Components of the Immune System

Pedro Berraondo, Clémence Nouzé, Xavier Préville, Daniel Ladant, and Claude Leclerc
Cancer Res 2007 67: 8847-8855. doi: 10.1158/0008-5472.CAN-07-0321 [Abstract] [Full Text] [PDF] Supplementary Data  

RAV12 Accelerates the Desensitization of Akt/PKB Pathway of Insulin-like Growth Factor I Receptor Signaling in COLO205

Jonathan Chi-Hang Li and Ronghao Li
Cancer Res 2007 67: 8856-8864. doi: 10.1158/0008-5472.CAN-07-0971 [Abstract] [Full Text] [PDF] Supplementary Data  

Immunology:

Expansion of Human T Regulatory Type 1 Cells in the Microenvironment of Cyclooxygenase 2 Overexpressing Head and Neck Squamous Cell Carcinoma

Christoph Bergmann, Laura Strauss, Reinhard Zeidler, Stephan Lang, and Theresa L. Whiteside
Cancer Res 2007 67: 8865-8873. doi: 10.1158/0008-5472.CAN-07-0767 [Abstract] [Full Text] [PDF]  

Increased Glioma Growth in Mice Depleted of Macrophages

Hugo Galarneau, Jérôme Villeneuve, Geneviève Gowing, Jean-Pierre Julien, and Luc Vallières
Cancer Res 2007 67: 8874-8881. doi: 10.1158/0008-5472.CAN-07-0177 [Abstract] [Full Text] [PDF] Supplementary Data  

Fc Optimization of Therapeutic Antibodies Enhances Their Ability to Kill Tumor Cells In vitro and Controls Tumor Expansion In vivo via Low-Affinity Activating Fc Receptors

Jeffrey B. Stavenhagen, Sergey Gorlatov, Nadine Tuaillon, Christopher T. Rankin, Hua Li, Stephen Burke, Ling Huang, Syd Johnson, Ezio Bonvini, and Scott Koenig
Cancer Res 2007 67: 8882-8890. doi: 10.1158/0008-5472.CAN-07-0696 [Abstract] [Full Text] [PDF] Supplementary Data  

Mechanisms Involved in Synergistic Anticancer Immunity of Anti-4-1BB and Anti-CD4 Therapy

Beom K. Choi, Young H. Kim, Woo J. Kang, Sun K. Lee, Kwang H. Kim, Su M. Shin, Wayne M. Yokoyama, Tae Y. Kim, and Byoung S. Kwon
Cancer Res 2007 67: 8891-8899. doi: 10.1158/0008-5472.CAN-07-1056 [Abstract] [Full Text] [PDF] Supplementary Data  

Relationship between B7-H4, Regulatory T Cells, and Patient Outcome in Human Ovarian Carcinoma

Ilona Kryczek, Shuang Wei, Gefeng Zhu, Leann Myers, Peter Mottram, Pui Cheng, Lieping Chen, George Coukos, and Weiping Zou
Cancer Res 2007 67: 8900-8905. doi: 10.1158/0008-5472.CAN-07-1866 [Abstract] [Full Text] [PDF]  

Endocrinology:

PC-1/PrLZ Contributes to Malignant Progression in Prostate Cancer

Hui Zhang, Jian Wang, Bo Pang, Rui-xia Liang, Suping Li, Pei-tang Huang, Ruoxiang Wang, Leland W.K. Chung, Haiyen E. Zhau, Cuifen Huang, and Jian-guang Zhou
Cancer Res 2007 67: 8906-8913. doi: 10.1158/0008-5472.CAN-06-4214 [Abstract] [Full Text] [PDF]  

Prostaglandin E₂ Induces Breast Cancer–Related Aromatase Promoters via Activation of p38 and c-Jun NH₂-Terminal Kinase in Adipose Fibroblasts

Dong Chen, Scott Reierstad, Zhihong Lin, Meiling Lu, Chris Brooks, Newton Li, Joy Innes, and Serdar E. Bulun
Cancer Res 2007 67: 8914-8922. doi: 10.1158/0008-5472.CAN-06-4751 [Abstract] [Full Text] [PDF] Supplementary Data  

Aberrant Huntingtin Interacting Protein 1 in Lymphoid Malignancies

Sarah V. Bradley, Mitchell R. Smith, Teresa S. Hyun, Peter C. Lucas, Lina Li, Danielle Antonuk, Indira Joshi, Fang Jin, and Theodora S. Ross
Cancer Res 2007 67: 8923-8931. doi: 10.1158/0008-5472.CAN-07-2153 [Abstract] [Full Text] [PDF] Supplementary Data  

17ß-Estradiol Up-regulates the Insulin-like Growth Factor Receptor through a Nongenotropic Pathway in Prostate Cancer Cells

Giuseppe Pandini, Marco Genua, Francesco Frasca, Sebastiano Squatrito, Riccardo Vigneri, and Antonino Belfiore
Cancer Res 2007 67: 8932-8941. doi: 10.1158/0008-5472.CAN-06-4814 [Abstract] [Full Text] [PDF]  

Progestins Reinitiate Cell Cycle Progression in Antiestrogen-Arrested Breast Cancer Cells through the B-Isoform of Progesterone Receptor

Eileen M. McGowan, Amanda J. Russell, Viroj Boonyaratanakornkit, Darren N. Saunders, Gillian M. Lehrbach, C. Marcelo Sergio, Elizabeth A. Musgrove, Dean P. Edwards, and Robert L. Sutherland
Cancer Res 2007 67: 8942-8951. doi: 10.1158/0008-5472.CAN-07-1255 [Abstract] [Full Text] [PDF]  

Novel Mechanism whereby Nuclear Factor B Mediates DNA Damage Repair through Regulation of O⁶-Methylguanine-DNA-Methyltransferase

Iris Lavon, Dana Fuchs, Daniel Zrihan, Gilat Efroni, Bracha Zelikovitch, Yakov Fellig, and Tali Siegal
Cancer Res 2007 67: 8952-8959. doi: 10.1158/0008-5472.CAN-06-3820 [Abstract] [Full Text] [PDF]  

Prevention:

Characterization of Viral Particles Isolated from Primary Cultures of Human Breast Cancer Cells

Stella M. Melana, Irene Nepomnaschy, Michael Sakalian, Andrea Abbott, Jennifer Hasa, James F. Holland, and Beatriz G.T. Pogo
Cancer Res 2007 67: 8960-8965. doi: 10.1158/0008-5472.CAN-06-3892 [Abstract] [Full Text] [PDF] Supplementary Data  

Tobacco Smoke Induces Urokinase-Type Plasminogen Activator and Cell Invasiveness: Evidence for an Epidermal Growth Factor Receptor–Dependent Mechanism

Baoheng Du, Helen Leung, K.M. Faisal Khan, Charles G. Miller, Kotha Subbaramaiah, Domenick J. Falcone, and Andrew J. Dannenberg
Cancer Res 2007 67: 8966-8972. doi: 10.1158/0008-5472.CAN-07-1388 [Abstract] [Full Text] [PDF]  

Corrections:

Correction: CD44, 2ß1, and Prostate Tumor Stem/Progenitors

Cancer Res 2007 67: 8973. doi: 10.1158/0008-5472.CAN-67-18-COR1 [Full Text] [PDF]  

Correction: iNOS Statins and Breast Cancer Cell Apoptosis

Cancer Res 2007 67: 8973. doi: 10.1158/0008-5472.CAN-67-18-COR2 [Full Text] [PDF]  

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