Reviews:

A New Central Scaffold for Metastasis: Parsing HEF1/Cas-L/NEDD9

Geraldine M. O'Neill, Sachiko Seo, Ilya G. Serebriiskii, Stuart R. Lessin, and Erica A. Golemis
Cancer Res 2007 67: 8975-8979. doi: 10.1158/0008-5472.CAN-07-1328 [Abstract] [Full Text] [PDF]  

Cancer Stem Cells in Radiation Resistance

Jeremy N. Rich
Cancer Res 2007 67: 8980-8984. doi: 10.1158/0008-5472.CAN-07-0895 [Abstract] [Full Text] [PDF]  

Perspectives in Cancer Research:

The Fuzzy Math of Solid Tumor Stem Cells: A Perspective

Scott E. Kern and Darryl Shibata
Cancer Res 2007 67: 8985-8988. doi: 10.1158/0008-5472.CAN-07-1971 [Abstract] [Full Text] [PDF]  

Meeting Report:

Meeting Report: Fifth Annual AACR Frontiers in Cancer Prevention Research

Ashraful Hoque, Howard L. Parnes, Michael E. Stefanek, John V. Heymach, Powel H. Brown, and Scott M. Lippman
Cancer Res 2007 67: 8989-8993. Published Online First September 25, 2007. doi: 10.1158/0008-5472.CAN-07-3171 [Abstract] [Full Text] [PDF]  

Priority Reports:

MicroRNA-21 Knockdown Disrupts Glioma Growth In vivo and Displays Synergistic Cytotoxicity with Neural Precursor Cell–Delivered S-TRAIL in Human Gliomas

Maarten F. Corsten, Rafael Miranda, Randa Kasmieh, Anna M. Krichevsky, Ralph Weissleder, and Khalid Shah
Cancer Res 2007 67: 8994-9000. doi: 10.1158/0008-5472.CAN-07-1045 [Abstract] [Full Text] [PDF]  

Evidence for Calpain-Mediated Androgen Receptor Cleavage as a Mechanism for Androgen Independence

Stephen J. Libertini, Clifford G. Tepper, Veronica Rodriguez, David M. Asmuth, Hsing-Jien Kung, and Maria Mudryj
Cancer Res 2007 67: 9001-9005. doi: 10.1158/0008-5472.CAN-07-1072 [Abstract] [Full Text] [PDF]  

FBXW7/hCDC4 Is a General Tumor Suppressor in Human Cancer

Shahab Akhoondi, Dahui Sun, Natalie von der Lehr, Sophia Apostolidou, Kathleen Klotz, Alena Maljukova, Diana Cepeda, Heidi Fiegl, Dimitra Dofou, Christian Marth, Elisabeth Mueller-Holzner, Martin Corcoran, Markus Dagnell, Sepideh Zabihi Nejad, Babak Noori Nayer, Mohammad Reza Zali, Johan Hansson, Susanne Egyhazi, Fredrik Petersson, Per Sangfelt, Hans Nordgren, Dan Grander, Steven I. Reed, Martin Widschwendter, Olle Sangfelt, and Charles Spruck
Cancer Res 2007 67: 9006-9012. doi: 10.1158/0008-5472.CAN-07-1320 [Abstract] [Full Text] [PDF] Supplementary Data  

Loss of the Mitochondrial Bioenergetic Capacity Underlies the Glucose Avidity of Carcinomas

Fernando López-Ríos, María Sánchez-Aragó, Elena García-García, Álvaro D. Ortega, José R. Berrendero, Francisco Pozo-Rodríguez, Ángel López-Encuentra, Claudio Ballestín, and José M. Cuezva
Cancer Res 2007 67: 9013-9017. doi: 10.1158/0008-5472.CAN-07-1678 [Abstract] [Full Text] [PDF]  

Trastuzumab-Resistant HER2-Driven Breast Cancer Cells Are Sensitive to Epigallocatechin-3 Gallate

Sean F. Eddy, Susan E. Kane, and Gail E. Sonenshein
Cancer Res 2007 67: 9018-9023. doi: 10.1158/0008-5472.CAN-07-1691 [Abstract] [Full Text] [PDF]  

Glucuronidation of Nicotine and Cotinine by UGT2B10: Loss of Function by the UGT2B10 Codon 67 (Asp>Tyr) Polymorphism

Gang Chen, Andrea S. Blevins-Primeau, Ryan W. Dellinger, Joshua E. Muscat, and Philip Lazarus
Cancer Res 2007 67: 9024-9029. doi: 10.1158/0008-5472.CAN-07-2245 [Abstract] [Full Text] [PDF]  

Opposing Function of the Proprotein Convertases Furin and PACE4 on Breast Cancer Cells' Malignant Phenotypes: Role of Tissue Inhibitors of Metalloproteinase-1

Marion Lapierre, Geraldine Siegfried, Nathalie Scamuffa, Yannick Bontemps, Fabien Calvo, Nabil G. Seidah, and Abdel-Majid Khatib
Cancer Res 2007 67: 9030-9034. doi: 10.1158/0008-5472.CAN-07-0807 [Abstract] [Full Text] [PDF]  

Fetal Microchimerism in Women with Breast Cancer

Vijayakrishna K. Gadi and J. Lee Nelson
Cancer Res 2007 67: 9035-9038. doi: 10.1158/0008-5472.CAN-06-4209 [Abstract] [Full Text] [PDF]  

Molecular Biology, Pathobiology, and Genetics:

A Novel Variant of Ileal Bile Acid Binding Protein Is Up-regulated through Nuclear Factor-B Activation in Colorectal Adenocarcinoma

Changming Fang, Jarrod Dean, and Jeffrey W. Smith
Cancer Res 2007 67: 9039-9046. doi: 10.1158/0008-5472.CAN-06-3690 [Abstract] [Full Text] [PDF] Supplementary Data  

Reduced Body Size and Decreased Intestinal Tumor Rates in HDAC2-Mutant Mice

Stephan Zimmermann, Franz Kiefer, Michela Prudenziati, Carmen Spiller, Jens Hansen, Thomas Floss, Wolfgang Wurst, Saverio Minucci, and Martin Göttlicher
Cancer Res 2007 67: 9047-9054. doi: 10.1158/0008-5472.CAN-07-0312 [Abstract] [Full Text] [PDF]  

High Cancer-Specific Expression of Mesothelin (MSLN) Is Attributable to an Upstream Enhancer Containing a Transcription Enhancer Factor–Dependent MCAT Motif

Tomas Hucl, Jonathan R. Brody, Eike Gallmeier, Christine A. Iacobuzio-Donahue, Iain K. Farrance, and Scott E. Kern
Cancer Res 2007 67: 9055-9065. doi: 10.1158/0008-5472.CAN-07-0474 [Abstract] [Full Text] [PDF]  

Epidermal Growth Factor Receptor Cooperates with Signal Transducer and Activator of Transcription 3 to Induce Epithelial-Mesenchymal Transition in Cancer Cells via Up-regulation of TWIST Gene Expression

Hui-Wen Lo, Sheng-Chieh Hsu, Weiya Xia, Xinyu Cao, Jin-Yuan Shih, Yongkun Wei, James L. Abbruzzese, Gabriel N. Hortobagyi, and Mien-Chie Hung
Cancer Res 2007 67: 9066-9076. doi: 10.1158/0008-5472.CAN-07-0575 [Abstract] [Full Text] [PDF]  

Cisplatin Depletes TREX2 and Causes Robertsonian Translocations as Seen in TREX2 Knockout Cells

Ming-Jiu Chen, Lavinia C. Dumitrache, Danny Wangsa, Sheng-Mei Ma, Hesed Padilla-Nash, Thomas Ried, and Paul Hasty
Cancer Res 2007 67: 9077-9083. doi: 10.1158/0008-5472.CAN-07-1146 [Abstract] [Full Text] [PDF] Supplementary Data  

Pediatric KIT–Wild-Type and Platelet-Derived Growth Factor Receptor –Wild-Type Gastrointestinal Stromal Tumors Share KIT Activation but not Mechanisms of Genetic Progression with Adult Gastrointestinal Stromal Tumors

Katherine A. Janeway, Bernadette Liegl, Amy Harlow, Claudia Le, Antonio Perez-Atayde, Harry Kozakewich, Christopher L. Corless, Michael C. Heinrich, and Jonathan A. Fletcher
Cancer Res 2007 67: 9084-9088. doi: 10.1158/0008-5472.CAN-07-1938 [Abstract] [Full Text] [PDF] Supplementary Data  

Prolonged Exposure to Reduced Levels of Androgen Accelerates Prostate Cancer Progression in Nkx3.1; Pten Mutant Mice

Whitney Banach-Petrosky, Walter J. Jessen, Xuesong Ouyang, Hui Gao, Jayashree Rao, John Quinn, Bruce J. Aronow, and Cory Abate-Shen
Cancer Res 2007 67: 9089-9096. doi: 10.1158/0008-5472.CAN-07-2887 [Abstract] [Full Text] [PDF] Supplementary Data  

The Ajuba LIM Domain Protein Is a Corepressor for SNAG Domain–Mediated Repression and Participates in Nucleocytoplasmic Shuttling

Kasirajan Ayyanathan, Hongzhuang Peng, Zhaoyuan Hou, William J. Fredericks, Rakesh K. Goyal, Ellen M. Langer, Gregory D. Longmore, and Frank J. Rauscher, III
Cancer Res 2007 67: 9097-9106. doi: 10.1158/0008-5472.CAN-07-2987 [Abstract] [Full Text] [PDF]  

Epigenetic Inactivation of a Cluster of Genes Flanking MLH1 in Microsatellite-Unstable Colorectal Cancer

Megan P. Hitchins, Vita Ap Lin, Andrew Buckle, Kayfong Cheong, Nimita Halani, Su Ku, Chau-To Kwok, Deborah Packham, Catherine M. Suter, Alan Meagher, Clare Stirzaker, Susan Clark, Nicholas J. Hawkins, and Robyn L. Ward
Cancer Res 2007 67: 9107-9116. doi: 10.1158/0008-5472.CAN-07-0869 [Abstract] [Full Text] [PDF] Supplementary Data  

Targeted Repression of Bone Morphogenetic Protein 7, a Novel Target of the p53 Family, Triggers Proliferative Defect in p53-Deficient Breast Cancer Cells

Wensheng Yan and Xinbin Chen
Cancer Res 2007 67: 9117-9124. doi: 10.1158/0008-5472.CAN-07-0996 [Abstract] [Full Text] [PDF] Supplementary Data  

Egr-1 Mediates Hypoxia-Inducible Transcription of the NDRG1 Gene through an Overlapping Egr-1/Sp1 Binding Site in the Promoter

Ping Zhang, Kam-Meng Tchou-Wong, and Max Costa
Cancer Res 2007 67: 9125-9133. doi: 10.1158/0008-5472.CAN-07-1525 [Abstract] [Full Text] [PDF]  

A CDKN2A Mutation in Familial Melanoma that Abrogates Binding of p16^INK4a to CDK4 but not CDK6

Rebecca Jones, Margarida Ruas, Fiona Gregory, Stephanie Moulin, Domenico Delia, Siranoush Manoukian, Janice Rowe, Sharon Brookes, and Gordon Peters
Cancer Res 2007 67: 9134-9141. doi: 10.1158/0008-5472.CAN-07-1528 [Abstract] [Full Text] [PDF]  

Cell, Tumor, and Stem Cell Biology:

Human Bone Marrow–Derived Mesenchymal Stem Cells Do Not Undergo Transformation after Long-term In vitro Culture and Do Not Exhibit Telomere Maintenance Mechanisms

Maria Ester Bernardo, Nadia Zaffaroni, Francesca Novara, Angela Maria Cometa, Maria Antonietta Avanzini, Antonia Moretta, Daniela Montagna, Rita Maccario, Raffaella Villa, Maria Grazia Daidone, Orsetta Zuffardi, and Franco Locatelli
Cancer Res 2007 67: 9142-9149. doi: 10.1158/0008-5472.CAN-06-4690 [Abstract] [Full Text] [PDF]  

Cell Division Cycle 25B Phosphatase Is Essential for Benzo(a)Pyrene-7,8-Diol-9,10-Epoxide–Induced Neoplastic Transformation

Sanjay K. Srivastava, Pallavi Bansal, Tetsuya Oguri, John S. Lazo, and Shivendra V. Singh
Cancer Res 2007 67: 9150-9157. doi: 10.1158/0008-5472.CAN-07-0025 [Abstract] [Full Text] [PDF] Supplementary Data  

Reduction in IB Kinase Expression Promotes the Development of Skin Papillomas and Carcinomas

Eunmi Park, Feng Zhu, Bigang Liu, Xiaojun Xia, Jianjun Shen, Tracie Bustos, Susan M. Fischer, and Yinling Hu
Cancer Res 2007 67: 9158-9168. doi: 10.1158/0008-5472.CAN-07-0590 [Abstract] [Full Text] [PDF] Supplementary Data  

Tenascin-W Is a Novel Marker for Activated Tumor Stroma in Low-grade Human Breast Cancer and Influences Cell Behavior

Martin Degen, Florence Brellier, Renate Kain, Christian Ruiz, Luigi Terracciano, Gertraud Orend, and Ruth Chiquet-Ehrismann
Cancer Res 2007 67: 9169-9179. doi: 10.1158/0008-5472.CAN-07-0666 [Abstract] [Full Text] [PDF]  

In vivo Imaging of the Systemic Recruitment of Fibroblasts to the Angiogenic Rim of Ovarian Carcinoma Tumors

Dorit Granot, Yoseph Addadi, Vyacheslav Kalchenko, Alon Harmelin, Leoni A. Kunz-Schughart, and Michal Neeman
Cancer Res 2007 67: 9180-9189. doi: 10.1158/0008-5472.CAN-07-0684 [Abstract] [Full Text] [PDF] Supplementary Data  

An Increased Expression of Cysteinyl Leukotriene 2 Receptor in Colorectal Adenocarcinomas Correlates with High Differentiation

Cecilia Magnusson, Roy Ehrnström, Jørgen Olsen, and Anita Sjölander
Cancer Res 2007 67: 9190-9198. doi: 10.1158/0008-5472.CAN-07-0771 [Abstract] [Full Text] [PDF]  

Roles for the Stem Cell–Associated Intermediate Filament Nestin in Prostate Cancer Migration and Metastasis

Wolfram Kleeberger, G. Steven Bova, Matthew E. Nielsen, Mehsati Herawi, Ai-Ying Chuang, Jonathan I. Epstein, and David M. Berman
Cancer Res 2007 67: 9199-9206. doi: 10.1158/0008-5472.CAN-07-0806 [Abstract] [Full Text] [PDF] Supplementary Data  

Snail-Induced Down-Regulation of Np63 Acquires Invasive Phenotype of Human Squamous Cell Carcinoma

Koichiro Higashikawa, Shingo Yoneda, Kei Tobiume, Masayuki Taki, Hideo Shigeishi, and Nobuyuki Kamata
Cancer Res 2007 67: 9207-9213. doi: 10.1158/0008-5472.CAN-07-0932 [Abstract] [Full Text] [PDF] Supplementary Data  

Signal Transducer and Activator of Transcription 1 Regulates Both Cytotoxic and Prosurvival Functions in Tumor Cells

Nikolai N. Khodarev, Andy J. Minn, Elena V. Efimova, Thomas E. Darga, Edwardine Labay, Michael Beckett, Helena J. Mauceri, Bernard Roizman, and Ralph R. Weichselbaum
Cancer Res 2007 67: 9214-9220. doi: 10.1158/0008-5472.CAN-07-1019 [Abstract] [Full Text] [PDF] Supplementary Data  

Whole-Genome Profiling in Liposarcomas Reveals Genetic Alterations Common to Specific Telomere Maintenance Mechanisms

Jay E. Johnson, Edward J. Gettings, Jaclyn Schwalm, Jianming Pei, Joseph R. Testa, Samuel Litwin, Margaret von Mehren, and Dominique Broccoli
Cancer Res 2007 67: 9221-9228. doi: 10.1158/0008-5472.CAN-07-1133 [Abstract] [Full Text] [PDF]  

The Phosphoinositide Kinase PIKfyve Mediates Epidermal Growth Factor Receptor Trafficking to the Nucleus

Jayoung Kim, Wan Jin Jahng, Dolores Di Vizio, Julie S. Lee, Raj Jhaveri, Mark A. Rubin, Assia Shisheva, and Michael R. Freeman
Cancer Res 2007 67: 9229-9237. doi: 10.1158/0008-5472.CAN-07-1333 [Abstract] [Full Text] [PDF]  

Relocalized p27^Kip1 Tumor Suppressor Functions as a Cytoplasmic Metastatic Oncogene in Melanoma

Catherine Denicourt, Cheryl C. Saenz, Brian Datnow, Xian-Shu Cui, and Steven F. Dowdy
Cancer Res 2007 67: 9238-9243. doi: 10.1158/0008-5472.CAN-07-1375 [Abstract] [Full Text] [PDF]  

In vivo Significance of the G₂ Restriction Point

Floris Foijer, Elly Delzenne-Goette, Marleen Dekker, and Hein te Riele
Cancer Res 2007 67: 9244-9247. doi: 10.1158/0008-5472.CAN-07-1650 [Abstract] [Full Text] [PDF]  

Glutathione Transferase Plays a Critical Role in the Development of Lung Carcinogenesis following Exposure to Tobacco-Related Carcinogens and Urethane

Kenneth J. Ritchie, Colin J. Henderson, Xiu Jun Wang, Olga Vassieva, Dianne Carrie, Peter B. Farmer, Margaret Gaskell, Kevin Park, and C. Roland Wolf
Cancer Res 2007 67: 9248-9257. doi: 10.1158/0008-5472.CAN-07-1764 [Abstract] [Full Text] [PDF]  

Inhibition of the Proteasome Activity by Gallium(III) Complexes Contributes to Their Anti–Prostate Tumor Effects

Di Chen, Michael Frezza, Rajendra Shakya, Qiuzhi Cindy Cui, Vesna Milacic, Claudio N. Verani, and Q. Ping Dou
Cancer Res 2007 67: 9258-9265. doi: 10.1158/0008-5472.CAN-07-1813 [Abstract] [Full Text] [PDF]  

Insulin Receptor Substrate-1 Is an Important Mediator of Ovarian Cancer Cell Growth Suppression by All-trans Retinoic Acid

Sharada Ravikumar, Georgina Perez-Liz, Luis Del Vale, Dianne Robert Soprano, and Kenneth J. Soprano
Cancer Res 2007 67: 9266-9275. doi: 10.1158/0008-5472.CAN-07-2088 [Abstract] [Full Text] [PDF]  

Cancer Resistance in Transgenic Mice Expressing the SAC Module of Par-4

Yanming Zhao, Ravshan Burikhanov, Shirley Qiu, Subodh M. Lele, C. Darrell Jennings, Subbarao Bondada, Brett Spear, and Vivek M. Rangnekar
Cancer Res 2007 67: 9276-9285. doi: 10.1158/0008-5472.CAN-07-2124 [Abstract] [Full Text] [PDF] Supplementary Data  

Nitric Oxide Inactivates the Retinoblastoma Pathway in Chronic Inflammation

Lei Ying, Anne B. Hofseth, Darren D. Browning, Mitzi Nagarkatti, Prakash S. Nagarkatti, and Lorne J. Hofseth
Cancer Res 2007 67: 9286-9293. doi: 10.1158/0008-5472.CAN-07-2238 [Abstract] [Full Text] [PDF] Supplementary Data  

Peroxiredoxin 1 Interacts with Androgen Receptor and Enhances Its Transactivation

Soo-Yeon Park, Xiaofei Yu, Clement Ip, James L. Mohler, Paul N. Bogner, and Young-Mee Park
Cancer Res 2007 67: 9294-9303. doi: 10.1158/0008-5472.CAN-07-0651 [Abstract] [Full Text] [PDF]  

Aberrant Expression of Cortactin in Head and Neck Squamous Cell Carcinoma Cells Is Associated with Enhanced Cell Proliferation and Resistance to the Epidermal Growth Factor Receptor Inhibitor Gefitinib

Paul Timpson, Ashleigh S. Wilson, Gillian M. Lehrbach, Robert L. Sutherland, Elizabeth A. Musgrove, and Roger J. Daly
Cancer Res 2007 67: 9304-9314. doi: 10.1158/0008-5472.CAN-07-0798 [Abstract] [Full Text] [PDF]  

ß-Catenin Regulates Multiple Steps of RNA Metabolism as Revealed by the RNA Aptamer in Colon Cancer Cells

Hee Kyu Lee, Ho Yoon Kwak, Jung Hur, In Ae Kim, Ji Sun Yang, Min Woo Park, Jaehoon Yu, and Sunjoo Jeong
Cancer Res 2007 67: 9315-9321. doi: 10.1158/0008-5472.CAN-07-1128 [Abstract] [Full Text] [PDF]  

The Alternative Reading Frame Tumor Suppressor Antagonizes Hypoxia-Induced Cancer Cell Migration via Interaction with the COOH-Terminal Binding Protein Corepressor

Seema Paliwal, Ramesh C. Kovi, Bharath Nath, Ya-Wen Chen, Brian C. Lewis, and Steven R. Grossman
Cancer Res 2007 67: 9322-9329. doi: 10.1158/0008-5472.CAN-07-1743 [Abstract] [Full Text] [PDF]  

Association of Wwox with ErbB4 in Breast Cancer

Rami I. Aqeilan, Valentina Donati, Eugenio Gaudio, Milena S. Nicoloso, Maria Sundvall, Anna Korhonen, Johan Lundin, Jorma Isola, Marius Sudol, Heikki Joensuu, Carlo M. Croce, and Klaus Elenius
Cancer Res 2007 67: 9330-9336. doi: 10.1158/0008-5472.CAN-07-2147 [Abstract] [Full Text] [PDF] Supplementary Data  

Experimental Therapeutics, Molecular Targets, and Chemical Biology:

Antitumor and Antivascular Effects of AVE8062 in Ovarian Carcinoma

Tae Jin Kim, Murali Ravoori, Charles N. Landen, Aparna A. Kamat, Liz Y. Han, Chunhua Lu, Yvonne G. Lin, William M. Merritt, Nicholas Jennings, Whitney A. Spannuth, Robert Langley, David M. Gershenson, Robert L. Coleman, Vikas Kundra, and Anil K. Sood
Cancer Res 2007 67: 9337-9345. doi: 10.1158/0008-5472.CAN-06-4018 [Abstract] [Full Text] [PDF] Supplementary Data  

The Activity of Zoledronic Acid on Neuroblastoma Bone Metastasis Involves Inhibition of Osteoclasts and Tumor Cell Survival and Proliferation

Hongjun Peng, Yasuyoshi Sohara, Rex A. Moats, Marvin D. Nelson, Jr., Susan G. Groshen, Wei Ye, C. Patrick Reynolds, and Yves A. DeClerck
Cancer Res 2007 67: 9346-9355. doi: 10.1158/0008-5472.CAN-06-4508 [Abstract] [Full Text] [PDF] Supplementary Data  

Class III ß-Tubulin Mediates Sensitivity to Chemotherapeutic Drugs in Non–Small Cell Lung Cancer

Pei Pei Gan, Eddy Pasquier, and Maria Kavallaris
Cancer Res 2007 67: 9356-9363. doi: 10.1158/0008-5472.CAN-07-0509 [Abstract] [Full Text] [PDF] Supplementary Data  

Serial Assessment of Human Tumor Burdens in Mice by the Analysis of Circulating DNA

Carlo Rago, David L. Huso, Frank Diehl, Baktiar Karim, Guosheng Liu, Nickolas Papadopoulos, Yardena Samuels, Victor E. Velculescu, Bert Vogelstein, Kenneth W. Kinzler, and Luis A. Diaz, Jr.
Cancer Res 2007 67: 9364-9370. doi: 10.1158/0008-5472.CAN-07-0605 [Abstract] [Full Text] [PDF]  

Systemic Therapy of Spontaneous Prostate Cancer in Transgenic Mice with Oncolytic Herpes Simplex Viruses

Susan Varghese, Samuel D. Rabkin, G. Petur Nielsen, Usha MacGarvey, Renbin Liu, and Robert L. Martuza
Cancer Res 2007 67: 9371-9379. doi: 10.1158/0008-5472.CAN-07-0674 [Abstract] [Full Text] [PDF]  

Targeting Cyclooxygenase-2 and the Epidermal Growth Factor Receptor for the Prevention and Treatment of Intestinal Cancer

F. Gregory Buchanan, Vijay Holla, Sharada Katkuri, Pranathi Matta, and Raymond N. DuBois
Cancer Res 2007 67: 9380-9388. doi: 10.1158/0008-5472.CAN-07-0710 [Abstract] [Full Text] [PDF]  

ABCG2/BCRP Expression Modulates D-Luciferin–Based Bioluminescence Imaging

Yimao Zhang, Joseph P. Bressler, Jeff Neal, Bachchu Lal, Hyo-Eun C. Bhang, John Laterra, and Martin G. Pomper
Cancer Res 2007 67: 9389-9397. doi: 10.1158/0008-5472.CAN-07-0944 [Abstract] [Full Text] [PDF] Supplementary Data  

Depletion of Peripheral Macrophages and Brain Microglia Increases Brain Tumor Titers of Oncolytic Viruses

Giulia Fulci, Nina Dmitrieva, Davide Gianni, Elisabeth J. Fontana, Xiaogang Pan, Yanhui Lu, Claire S. Kaufman, Balveen Kaur, Sean E. Lawler, Robert J. Lee, Clay B. Marsh, Daniel J. Brat, Nico van Rooijen, Anat Stemmer Rachamimov, Fred H. Hochberg, Ralph Weissleder, Robert L. Martuza, and E. Antonio Chiocca
Cancer Res 2007 67: 9398-9406. doi: 10.1158/0008-5472.CAN-07-1063 [Abstract] [Full Text] [PDF] Supplementary Data  

Triptolide Induces Pancreatic Cancer Cell Death via Inhibition of Heat Shock Protein 70

Phoebe A. Phillips, Vikas Dudeja, Joshua A. McCarroll, Daniel Borja-Cacho, Rajinder K. Dawra, William E. Grizzle, Selwyn M. Vickers, and Ashok K. Saluja
Cancer Res 2007 67: 9407-9416. doi: 10.1158/0008-5472.CAN-07-1077 [Abstract] [Full Text] [PDF]  

Targeting CCL2 with Systemic Delivery of Neutralizing Antibodies Induces Prostate Cancer Tumor Regression In vivo

Robert D. Loberg, Chi Ying, Matt Craig, Lashon L. Day, Erin Sargent, Chris Neeley, Kirk Wojno, Linda A. Snyder, Li Yan, and Kenneth J. Pienta
Cancer Res 2007 67: 9417-9424. doi: 10.1158/0008-5472.CAN-07-1286 [Abstract] [Full Text] [PDF]  

c-Fos as a Proapoptotic Agent in TRAIL-Induced Apoptosis in Prostate Cancer Cells

Xiaoping Zhang, Liang Zhang, Hongmei Yang, Xu Huang, Hasan Otu, Towia A. Libermann, William C. DeWolf, Roya Khosravi-Far, and Aria F. Olumi
Cancer Res 2007 67: 9425-9434. doi: 10.1158/0008-5472.CAN-07-1310 [Abstract] [Full Text] [PDF] Supplementary Data  

Malignant Progression and Blockade of Angiogenesis in a Murine Transgenic Model of Neuroblastoma

Louis Chesler, David D. Goldenberg, Isha T. Seales, Ronit Satchi-Fainaro, Matt Grimmer, Rodney Collins, Chris Struett, Kim N. Nguyen, Grace Kim, Tarik Tihan, Yun Bao, Rolf A. Brekken, Gabriele Bergers, Judah Folkman, and William A. Weiss
Cancer Res 2007 67: 9435-9442. doi: 10.1158/0008-5472.CAN-07-1316 [Abstract] [Full Text] [PDF] Supplementary Data  

Cell Cycle–Dependent and Schedule-Dependent Antitumor Effects of Sorafenib Combined with Radiation

John P. Plastaras, Seok-Hyun Kim, Yingqiu Y. Liu, David T. Dicker, Jay F. Dorsey, James McDonough, George Cerniglia, Ramji R. Rajendran, Anjali Gupta, Anil K. Rustgi, J. Alan Diehl, Charles D. Smith, Keith T. Flaherty, and Wafik S. El-Deiry
Cancer Res 2007 67: 9443-9454. doi: 10.1158/0008-5472.CAN-07-1473 [Abstract] [Full Text] [PDF] Supplementary Data  

Tumor Necrosis Factor Mediates Homogeneous Distribution of Liposomes in Murine Melanoma that Contributes to a Better Tumor Response

Ann L.B. Seynhaeve, Saske Hoving, Debby Schipper, Cindy E. Vermeulen, Gisela aan de Wiel-Ambagtsheer, Sandra T. van Tiel, Alexander M.M. Eggermont, and Timo L.M. ten Hagen
Cancer Res 2007 67: 9455-9462. doi: 10.1158/0008-5472.CAN-07-1599 [Abstract] [Full Text] [PDF] Supplementary Data  

Autocrine Glutamate Signaling Promotes Glioma Cell Invasion

Susan A. Lyons, W. Joon Chung, Amy K. Weaver, Toyin Ogunrinu, and Harald Sontheimer
Cancer Res 2007 67: 9463-9471. doi: 10.1158/0008-5472.CAN-07-2034 [Abstract] [Full Text] [PDF]  

Inhibitors of Ubiquitin-Activating Enzyme (E1), a New Class of Potential Cancer Therapeutics

Yili Yang, Jirouta Kitagaki, Ren-Ming Dai, Yien Che Tsai, Kevin L. Lorick, Robert L. Ludwig, Shervon A. Pierre, Jane P. Jensen, Ilia V. Davydov, Pankaj Oberoi, Chou-Chi H. Li, John H. Kenten, John A. Beutler, Karen H. Vousden, and Allan M. Weissman
Cancer Res 2007 67: 9472-9481. doi: 10.1158/0008-5472.CAN-07-0568 [Abstract] [Full Text] [PDF] Supplementary Data  

Heat Shock Protein 90 Recruits FLIP_S to the Death-Inducing Signaling Complex and Contributes to TRAIL Resistance in Human Glioma

Amith Panner, Joseph C. Murray, Mitchel S. Berger, and Russell O. Pieper
Cancer Res 2007 67: 9482-9489. doi: 10.1158/0008-5472.CAN-07-0569 [Abstract] [Full Text] [PDF]  

The Multikinase Inhibitor Sorafenib Potentiates TRAIL Lethality in Human Leukemia Cells in Association with Mcl-1 and cFLIP_L Down-regulation

Roberto R. Rosato, Jorge A. Almenara, Stefanie Coe, and Steven Grant
Cancer Res 2007 67: 9490-9500. doi: 10.1158/0008-5472.CAN-07-0598 [Abstract] [Full Text] [PDF] Supplementary Data  

Local Administration of Interleukin-11 Ameliorates Intestinal Radiation Injury in Rats

Marjan Boerma, Junru Wang, Alexander F. Burnett, Alessandro D. Santin, Juan J. Roman, and Martin Hauer-Jensen
Cancer Res 2007 67: 9501-9506. doi: 10.1158/0008-5472.CAN-07-0810 [Abstract] [Full Text] [PDF]  

Immunology:

Phage Display–Derived Human Monoclonal Antibodies Isolated by Binding to the Surface of Live Primary Breast Cancer Cells Recognize GRP78

Charlotte G. Jakobsen, Nicolaj Rasmussen, Anne-Vibeke Laenkholm, and Henrik J. Ditzel
Cancer Res 2007 67: 9507-9517. doi: 10.1158/0008-5472.CAN-06-4686 [Abstract] [Full Text] [PDF] Supplementary Data  

Dynamics of the Immune Reaction to Pancreatic Cancer from Inception to Invasion

Carolyn E. Clark, Sunil R. Hingorani, Rosemarie Mick, Chelsea Combs, David A. Tuveson, and Robert H. Vonderheide
Cancer Res 2007 67: 9518-9527. doi: 10.1158/0008-5472.CAN-07-0175 [Abstract] [Full Text] [PDF] Supplementary Data  

A Placenta-Specific Gene Ectopically Activated in Many Human Cancers Is Essentially Involved in Malignant Cell Processes

Michael Koslowski, Ugur Sahin, Rita Mitnacht-Kraus, Gerhard Seitz, Christoph Huber, and Özlem Türeci
Cancer Res 2007 67: 9528-9534. doi: 10.1158/0008-5472.CAN-07-1350 [Abstract] [Full Text] [PDF] Supplementary Data  

Enhancement of Antibody-Dependent Mechanisms of Tumor Cell Lysis by a Targeted Activator of Complement

Masaki Imai, Rieko Ohta, Juan C. Varela, Hongbin Song, and Stephen Tomlinson
Cancer Res 2007 67: 9535-9541. doi: 10.1158/0008-5472.CAN-07-1690 [Abstract] [Full Text] [PDF]  

Endocrinology:

Accelerated Bone Resorption, Due to Dietary Calcium Deficiency, Promotes Breast Cancer Tumor Growth in Bone

Yu Zheng, Hong Zhou, James R.K. Modzelewski, Robert Kalak, Julie M. Blair, Markus J. Seibel, and Colin R. Dunstan
Cancer Res 2007 67: 9542-9548. doi: 10.1158/0008-5472.CAN-07-1046 [Abstract] [Full Text] [PDF]  

Definition of Functionally Important Mechanistic Differences among Selective Estrogen Receptor Down-regulators

Bryan M. Wittmann, Andrea Sherk, and Donald P. McDonnell
Cancer Res 2007 67: 9549-9560. doi: 10.1158/0008-5472.CAN-07-1590 [Abstract] [Full Text] [PDF]  

Association Study of 69 Genes in the Ret Pathway Identifies Low-penetrance Loci in Sporadic Medullary Thyroid Carcinoma

Sergio Ruiz-Llorente, Cristina Montero-Conde, Roger L. Milne, Christian M. Moya, Arancha Cebrián, Rocío Letón, Alberto Cascón, Fátima Mercadillo, Iñigo Landa, Salud Borrego, Guiomar Pérez de Nanclares, Cristina Álvarez-Escolá, José Ángel Díaz-Pérez, Ángel Carracedo, Miguel Urioste, Anna González-Neira, Javier Benítez, Pilar Santisteban, Joaquín Dopazo, Bruce A. Ponder, Mercedes Robledo, and the Medullary Thyroid Carcinoma Clinical Group
Cancer Res 2007 67: 9561-9567. doi: 10.1158/0008-5472.CAN-07-1638 [Abstract] [Full Text] [PDF] Supplementary Data  

Clinical Research:

SND1, a Component of RNA-Induced Silencing Complex, Is Up-regulated in Human Colon Cancers and Implicated in Early Stage Colon Carcinogenesis

Naoto Tsuchiya, Masako Ochiai, Katsuhiko Nakashima, Tsuneyuki Ubagai, Takashi Sugimura, and Hitoshi Nakagama
Cancer Res 2007 67: 9568-9576. doi: 10.1158/0008-5472.CAN-06-2707 [Abstract] [Full Text] [PDF] Supplementary Data  

Smad7 Sensitizes Tumor Necrosis Factor–Induced Apoptosis through the Inhibition of Antiapoptotic Gene Expression by Suppressing Activation of the Nuclear Factor-B Pathway

Suntaek Hong, Chan Lee, and Seong-Jin Kim
Cancer Res 2007 67: 9577-9583. doi: 10.1158/0008-5472.CAN-07-1179 [Abstract] [Full Text] [PDF] Supplementary Data  

Epidemiology:

Do MDM2 SNP309 and TP53 R72P Interact in Breast Cancer Susceptibility? A Large Pooled Series from the Breast Cancer Association Consortium

Marjanka K. Schmidt, Scarlett Reincke, Annegien Broeks, Linde M. Braaf, Frans B.L. Hogervorst, Rob A.E.M. Tollenaar, Nichola Johnson, Olivia Fletcher, Julian Peto, Johanna Tommiska, Carl Blomqvist, Heli A. Nevanlinna, Catherine S. Healey, Alison M. Dunning, Paul D.P. Pharoah, Douglas F. Easton, Thilo Dörk, Laura J. Van't Veer on behalf of the Breast Cancer Association Consortium
Cancer Res 2007 67: 9584-9590. doi: 10.1158/0008-5472.CAN-07-0738 [Abstract] [Full Text] [PDF]  

Genetic Heterogeneity among Fanconi Anemia Heterozygotes and Risk of Cancer

Marianne Berwick, Jaya M. Satagopan, Leah Ben-Porat, Ann Carlson, Katherine Mah, Rashida Henry, Raffaella Diotti, Kelly Milton, Kanan Pujara, Tom Landers, Sat Dev Batish, José Morales, Detlev Schindler, Helmut Hanenberg, Robert Hromas, Orna Levran, and Arleen D. Auerbach
Cancer Res 2007 67: 9591-9596. doi: 10.1158/0008-5472.CAN-07-1501 [Abstract] [Full Text] [PDF]  

The Cooked Meat–Derived Genotoxic Carcinogen 2-Amino-3-Methylimidazo[4,5-b]Pyridine Has Potent Hormone-Like Activity: Mechanistic Support for a Role in Breast Cancer

Sandra N. Lauber and Nigel J. Gooderham
Cancer Res 2007 67: 9597-9602. doi: 10.1158/0008-5472.CAN-07-1661 [Abstract] [Full Text] [PDF]  

Letter to the Editor:

Comment on: Screening for Lynch Syndrome (Hereditary Nonpolyposis Colorectal Cancer) among Endometrial Cancer Patients

Heather Hampel, Jenny Panescu, Janet Lockman, Kaisa Sotamaa, Daniel Fix, Ilene Comeras, Jennifer LaJeunesse, Hidewaki Nakagawa, Judith A. Westman, Thomas W. Prior, Mark Clendenning, Albert de la Chapelle, Wendy Frankel, Pamela Penzone, David E. Cohn, Larry Copeland, Lynne Eaton, Jeffrey Fowler, Janet Lombardi, Patti Dunn, Jeffrey Bell, Gary Reid, George Lewandowski, and Luis Vaccarello
Cancer Res 2007 67: 9603 [Full Text] [PDF]  

To see an article, click its [Full Text] or [PDF] link. To review many abstracts, check the boxes to the left of the titles you want, and click the 'Get All Checked Abstract(s)' button. To see one abstract at a time, click its [Abstract] link.