Reviews:

Notch Signaling, -Secretase Inhibitors, and Cancer Therapy

Ie-Ming Shih and Tian-Li Wang
Cancer Res 2007 67: 1879-1882. doi: 10.1158/0008-5472.CAN-06-3958 [Abstract] [Full Text] [PDF]  

The Adaptive Immunologic Microenvironment in Colorectal Cancer: A Novel Perspective

Jérôme Galon, Wolf-Herman Fridman, and Franck Pagès
Cancer Res 2007 67: 1883-1886. doi: 10.1158/0008-5472.CAN-06-4806 [Abstract] [Full Text] [PDF]  

Priority Reports:

Immunoediting Sculpts Tumor Epitopes during Immunotherapy

Reshma Singh and Yvonne Paterson
Cancer Res 2007 67: 1887-1892. doi: 10.1158/0008-5472.CAN-06-3960 [Abstract] [Full Text] [PDF] Supplementary Data  

Genetic Variation at the CYP19A1 Locus Predicts Circulating Estrogen Levels but not Breast Cancer Risk in Postmenopausal Women

Christopher A. Haiman, Laure Dossus, V. Wendy Setiawan, Daniel O. Stram, Alison M. Dunning, Gilles Thomas, Michael J. Thun, Demetrius Albanes, David Altshuler, Eva Ardanaz, Heiner Boeing, Julie Buring, Noël Burtt, Eugenia E. Calle, Stephen Chanock, Françoise Clavel-Chapelon, Graham A. Colditz, David G. Cox, Heather Spencer Feigelson, Susan E. Hankinson, Richard B. Hayes, Brian E. Henderson, Joel N. Hirschhorn, Robert Hoover, David J. Hunter, Rudolf Kaaks, Laurence N. Kolonel, Loïc Le Marchand, Per Lenner, Eiliv Lund, Salvatore Panico, Petra H. Peeters, Malcolm C. Pike, Elio Riboli, Anne Tjonneland, Ruth Travis, Dimitrios Trichopoulos, Sholom Wacholder, and Regina G. Ziegler
Cancer Res 2007 67: 1893-1897. Published Online First February 26, 2007. doi: 10.1158/0008-5472.CAN-06-4123 [Abstract] [Full Text] [PDF] Supplementary Data  

CD4 T-Helper Responses to the Anaplastic Lymphoma Kinase (ALK) Protein in Patients with ALK-Positive Anaplastic Large-Cell Lymphoma

Kamel Ait-Tahar, Martin C.N. Barnardo, and Karen Pulford
Cancer Res 2007 67: 1898-1901. doi: 10.1158/0008-5472.CAN-06-4427 [Abstract] [Full Text] [PDF]  

Molecular Biology, Pathobiology, and Genetics:

Identification of the Benign Mesenchymal Tumor Gene HMGA2 in Lymphangiomyomatosis

Jeanine D'Armiento, Kazushi Imai, John Schiltz, Natalya Kolesnekova, David Sternberg, Kathleen Benson, Annie Pardo, Moises Selman, Theresa Smolarek, Murty Vundavalli, Joshua Sonnet, Matthias Szabolcs, and Kiran Chada
Cancer Res 2007 67: 1902-1909. doi: 10.1158/0008-5472.CAN-06-1122 [Abstract] [Full Text] [PDF]  

Reduced Apoptosis and Increased Deletion Mutations at Aprt Locus In vivo in Mice Exposed to Repeated Ionizing Radiation

Li Liang, Marc S. Mendonca, Li Deng, Son C. Nguyen, Changshun Shao, and Jay A. Tischfield
Cancer Res 2007 67: 1910-1917. doi: 10.1158/0008-5472.CAN-06-1476 [Abstract] [Full Text] [PDF]  

Elevated Expression of the Oncogene c-fms and Its Ligand, the Macrophage Colony-Stimulating Factor-1, in Cervical Cancer and the Role of Transforming Growth Factor-ß1 in Inducing c-fms Expression

Nameer Kirma, Luciano S. Hammes, Ya-Guang Liu, Hareesh B. Nair, Philip T. Valente, Shantha Kumar, Lisa C. Flowers, and Rajeshwar Rao Tekmal
Cancer Res 2007 67: 1918-1926. doi: 10.1158/0008-5472.CAN-06-1991 [Abstract] [Full Text] [PDF] Supplementary Data  

Inactivation of the Candidate Tumor Suppressor Par-4 in Endometrial Cancer

Gema Moreno-Bueno, Pablo J. Fernandez-Marcos, Manuel Collado, Mercedes J. Tendero, Socorro M. Rodriguez-Pinilla, Isabel Garcia-Cao, David Hardisson, Maria T. Diaz-Meco, Jorge Moscat, Manuel Serrano, and Jose Palacios
Cancer Res 2007 67: 1927-1934. doi: 10.1158/0008-5472.CAN-06-2687 [Abstract] [Full Text] [PDF] Supplementary Data  

The Asn⁴¹⁸-Linked N-Glycan of ErbB3 Plays a Crucial Role in Preventing Spontaneous Heterodimerization and Tumor Promotion

Shunichi Yokoe, Motoko Takahashi, Michio Asahi, Seung Ho Lee, Wei Li, Daisuke Osumi, Eiji Miyoshi, and Naoyuki Taniguchi
Cancer Res 2007 67: 1935-1942. doi: 10.1158/0008-5472.CAN-06-3023 [Abstract] [Full Text] [PDF] Supplementary Data  

Intersex-like (IXL) Is a Cell Survival Regulator in Pancreatic Cancer with 19q13 Amplification

Riina Kuuselo, Kimmo Savinainen, David O. Azorsa, Gargi D. Basu, Ritva Karhu, Sukru Tuzmen, Spyro Mousses, and Anne Kallioniemi
Cancer Res 2007 67: 1943-1949. doi: 10.1158/0008-5472.CAN-06-3387 [Abstract] [Full Text] [PDF] Supplementary Data  

Breaking Chemoresistance and Radioresistance with [²¹³Bi]anti-CD45 Antibodies in Leukemia Cells

Claudia Friesen, Gerhard Glatting, Bernd Koop, Klaus Schwarz, Alfred Morgenstern, Christos Apostolidis, Klaus-Michael Debatin, and Sven N. Reske
Cancer Res 2007 67: 1950-1958. doi: 10.1158/0008-5472.CAN-06-3569 [Abstract] [Full Text] [PDF]  

The p53 Isoform p53 Lacks Intrinsic Transcriptional Activity and Reveals the Critical Role of Nuclear Import in Dominant-Negative Activity

Wan Mui Chan and Randy Y.C. Poon
Cancer Res 2007 67: 1959-1969. doi: 10.1158/0008-5472.CAN-06-3602 [Abstract] [Full Text] [PDF]  

Twist and Epithelial-Mesenchymal Transition Are Induced by the EBV Oncoprotein Latent Membrane Protein 1 and Are Associated with Metastatic Nasopharyngeal Carcinoma

Toshiyuki Horikawa, Jing Yang, Satoru Kondo, Tomokazu Yoshizaki, Irene Joab, Mitsuru Furukawa, and Joseph S. Pagano
Cancer Res 2007 67: 1970-1978. doi: 10.1158/0008-5472.CAN-06-3933 [Abstract] [Full Text] [PDF]  

Twist Transcriptionally Up-regulates AKT2 in Breast Cancer Cells Leading to Increased Migration, Invasion, and Resistance to Paclitaxel

George Z. Cheng, Joseph Chan, Qi Wang, Weizhou Zhang, Calvin D. Sun, and Lu-Hai Wang
Cancer Res 2007 67: 1979-1987. doi: 10.1158/0008-5472.CAN-06-1479 [Abstract] [Full Text] [PDF] Supplementary Data  

Curcumin, a Dietary Component, Has Anticancer, Chemosensitization, and Radiosensitization Effects by Down-regulating the MDM2 Oncogene through the PI3K/mTOR/ETS2 Pathway

Mao Li, Zhuo Zhang, Donald L. Hill, Hui Wang, and Ruiwen Zhang
Cancer Res 2007 67: 1988-1996. doi: 10.1158/0008-5472.CAN-06-3066 [Abstract] [Full Text] [PDF]  

RIL, a LIM Gene on 5q31, Is Silenced by Methylation in Cancer and Sensitizes Cancer Cells to Apoptosis

Yanis A. Boumber, Yutaka Kondo, Xuqi Chen, Lanlan Shen, Vazganush Gharibyan, Kazuo Konishi, Elihu Estey, Hagop Kantarjian, Guillermo Garcia-Manero, and Jean-Pierre J. Issa
Cancer Res 2007 67: 1997-2005. doi: 10.1158/0008-5472.CAN-06-3093 [Abstract] [Full Text] [PDF] Supplementary Data  

PARC and CUL7 Form Atypical Cullin RING Ligase Complexes

Jeffrey R. Skaar, Laurence Florens, Takeya Tsutsumi, Takehiro Arai, Adriana Tron, Selene K. Swanson, Michael P. Washburn, and James A. DeCaprio
Cancer Res 2007 67: 2006-2014. doi: 10.1158/0008-5472.CAN-06-3241 [Abstract] [Full Text] [PDF] Supplementary Data  

Cyclooxygenase-2 Inhibits UVB-Induced Apoptosis in Mouse Skin by Activating the Prostaglandin E₂ Receptors, EP2 and EP4

Kyung-Soo Chun, Jacqueline K. Akunda, and Robert Langenbach
Cancer Res 2007 67: 2015-2021. doi: 10.1158/0008-5472.CAN-06-3617 [Abstract] [Full Text] [PDF]  

Cell, Tumor, and Stem Cell Biology:

Effect of the Silybin-Phosphatidylcholine Complex (IdB 1016) on the Development of Mammary Tumors in HER-2/neu Transgenic Mice

Mauro Provinciali, Francesca Papalini, Fiorenza Orlando, Sara Pierpaoli, Alessia Donnini, Paolo Morazzoni, Antonella Riva, and Arianna Smorlesi
Cancer Res 2007 67: 2022-2029. doi: 10.1158/0008-5472.CAN-06-2601 [Abstract] [Full Text] [PDF]  

Engagement of Collagen-Binding Integrins Promotes Matrix Metalloproteinase-9–Dependent E-Cadherin Ectodomain Shedding in Ovarian Carcinoma Cells

Jaime Symowicz, Brian P. Adley, Kara J. Gleason, Jeffrey J. Johnson, Supurna Ghosh, David A. Fishman, Laurie G. Hudson, and M. Sharon Stack
Cancer Res 2007 67: 2030-2039. doi: 10.1158/0008-5472.CAN-06-2808 [Abstract] [Full Text] [PDF]  

Chronic Suppression of Angiogenesis following Radiation Exposure Is Independent of Hematopoietic Reconstitution

Taturo Udagawa, Amy E. Birsner, Mark Wood, and Robert J. D'Amato
Cancer Res 2007 67: 2040-2045. doi: 10.1158/0008-5472.CAN-06-2877 [Abstract] [Full Text] [PDF]  

Differential Constitutive Activation of the Epidermal Growth Factor Receptor in Non–Small Cell Lung Cancer Cells Bearing EGFR Gene Mutation and Amplification

Takafumi Okabe, Isamu Okamoto, Kenji Tamura, Masaaki Terashima, Takeshi Yoshida, Taroh Satoh, Minoru Takada, Masahiro Fukuoka, and Kazuhiko Nakagawa
Cancer Res 2007 67: 2046-2053. doi: 10.1158/0008-5472.CAN-06-3339 [Abstract] [Full Text] [PDF]  

Deletion of p37^Ing1 in Mice Reveals a p53-Independent Role for Ing1 in the Suppression of Cell Proliferation, Apoptosis, and Tumorigenesis

Andrew H. Coles, Huiling Liang, Zhiqing Zhu, Concetta G.A. Marfella, Joonsoo Kang, Anthony N. Imbalzano, and Stephen N. Jones
Cancer Res 2007 67: 2054-2061. doi: 10.1158/0008-5472.CAN-06-3558 [Abstract] [Full Text] [PDF]  

Systemic Stromal Effects of Estrogen Promote the Growth of Estrogen Receptor–Negative Cancers

Piyush B. Gupta, David Proia, Oya Cingoz, Janusz Weremowicz, Stephen P. Naber, Robert A. Weinberg, and Charlotte Kuperwasser
Cancer Res 2007 67: 2062-2071. doi: 10.1158/0008-5472.CAN-06-3895 [Abstract] [Full Text] [PDF] Supplementary Data  

Serine-Arginine Protein Kinase 1 Overexpression Is Associated with Tumorigenic Imbalance in Mitogen-Activated Protein Kinase Pathways in Breast, Colonic, and Pancreatic Carcinomas

Gregory M. Hayes, Patricia E. Carrigan, and Laurence J. Miller
Cancer Res 2007 67: 2072-2080. doi: 10.1158/0008-5472.CAN-06-2969 [Abstract] [Full Text] [PDF]  

Lung Cancer Cell Lines Harboring MET Gene Amplification Are Dependent on Met for Growth and Survival

Bart Lutterbach, Qinwen Zeng, Lenora J. Davis, Harold Hatch, Gaozhen Hang, Nancy E. Kohl, Jackson B. Gibbs, and Bo-Sheng Pan
Cancer Res 2007 67: 2081-2088. doi: 10.1158/0008-5472.CAN-06-3495 [Abstract] [Full Text] [PDF] Supplementary Data  

Osteopontin Promotes Integrin Activation through Outside-In and Inside-Out Mechanisms: OPN-CD44_V Interaction Enhances Survival in Gastrointestinal Cancer Cells

Jia-Lin Lee, Mei-Jung Wang, Putty-Reddy Sudhir, Gen-Der Chen, Chin-Wen Chi, and Jeou-Yuan Chen
Cancer Res 2007 67: 2089-2097. doi: 10.1158/0008-5472.CAN-06-3625 [Abstract] [Full Text] [PDF] Supplementary Data  

K-Ras Promotes Growth Transformation and Invasion of Immortalized Human Pancreatic Cells by Raf and Phosphatidylinositol 3-Kinase Signaling

Paul M. Campbell, Angela L. Groehler, Kwang M. Lee, Michel M. Ouellette, Vladimir Khazak, and Channing J. Der
Cancer Res 2007 67: 2098-2106. doi: 10.1158/0008-5472.CAN-06-3752 [Abstract] [Full Text] [PDF]  

The Possible Role of Cytokeratin 8 in Cadmium-Induced Adaptation and Carcinogenesis

Andy T.Y. Lau and Jen-Fu Chiu
Cancer Res 2007 67: 2107-2113. doi: 10.1158/0008-5472.CAN-06-3771 [Abstract] [Full Text] [PDF]  

GATA-1 Is Essential in EGF-Mediated Induction of Nucleotide Excision Repair Activity and ERCC1 Expression through ERK2 in Human Hepatoma Cells

Lise O. Andrieux, Alain Fautrel, Anne Bessard, André Guillouzo, Georges Baffet, and Sophie Langouët
Cancer Res 2007 67: 2114-2123. doi: 10.1158/0008-5472.CAN-06-3821 [Abstract] [Full Text] [PDF]  

Insulin Receptor Substrate-1 Regulates the Transformed Phenotype of BT-20 Human Mammary Cancer Cells

Ozlem Dalmizrak, An Wu, Jia Chen, Hongzhi Sun, Fransiscus E. Utama, Diana Zambelli, Thai H. Tran, Hallgeir Rui, and Renato Baserga
Cancer Res 2007 67: 2124-2130. doi: 10.1158/0008-5472.CAN-06-3954 [Abstract] [Full Text] [PDF]  

Experimental Therapeutics, Molecular Targets, and Chemical Biology:

Leukemia Inhibitory Factor: A Newly Identified Metastatic Factor in Rhabdomyosarcomas

Marcin Wysoczynski, Katarzyna Miekus, Kacper Jankowski, Jens Wanzeck, Salvatore Bertolone, Anna Janowska-Wieczorek, Janina Ratajczak, and Mariusz Z. Ratajczak
Cancer Res 2007 67: 2131-2140. doi: 10.1158/0008-5472.CAN-06-1021 [Abstract] [Full Text] [PDF]  

Down-regulation of Apurinic/Apyrimidinic Endonuclease 1/Redox Factor-1 Expression by Soy Isoflavones Enhances Prostate Cancer Radiotherapy In vitro and In vivo

Julian J. Raffoul, Sanjeev Banerjee, Vinita Singh-Gupta, Zvi E. Knoll, Alemu Fite, Hao Zhang, Judith Abrams, Fazlul H. Sarkar, and Gilda G. Hillman
Cancer Res 2007 67: 2141-2149. doi: 10.1158/0008-5472.CAN-06-2147 [Abstract] [Full Text] [PDF]  

Metabolomics by Proton Nuclear Magnetic Resonance Spectroscopy of the Response to Chloroethylnitrosourea Reveals Drug Efficacy and Tumor Adaptive Metabolic Pathways

Daniel Morvan and Aicha Demidem
Cancer Res 2007 67: 2150-2159. doi: 10.1158/0008-5472.CAN-06-2346 [Abstract] [Full Text] [PDF]  

Mammalian Target of Rapamycin Inhibitors as Possible Adjuvant Therapy for Microscopic Residual Disease in Head and Neck Squamous Cell Cancer

Cherie-Ann O. Nathan, Nazanin Amirghahari, Xiaohua Rong, Tony Giordano, Don Sibley, Mary Nordberg, Jonathan Glass, Anshul Agarwal, and Gloria Caldito
Cancer Res 2007 67: 2160-2168. doi: 10.1158/0008-5472.CAN-06-2449 [Abstract] [Full Text] [PDF]  

High-Throughput Screening Identifies Novel Agents Eliciting Hypersensitivity in Fanconi Pathway–Deficient Cancer Cells

Eike Gallmeier, Tomas Hucl, Jonathan R. Brody, David A. Dezentje, Khola Tahir, Jana Kasparkova, Viktor Brabec, Kurtis E. Bachman, and Scott E. Kern
Cancer Res 2007 67: 2169-2177. doi: 10.1158/0008-5472.CAN-06-2711 [Abstract] [Full Text] [PDF]  

Synthetic Affibody Molecules: A Novel Class of Affinity Ligands for Molecular Imaging of HER2-Expressing Malignant Tumors

Anna Orlova, Vladimir Tolmachev, Rikard Pehrson, Malin Lindborg, Thuy Tran, Mattias Sandström, Fredrik Y. Nilsson, Anders Wennborg, Lars Abrahmsén, and Joachim Feldwisch
Cancer Res 2007 67: 2178-2186. doi: 10.1158/0008-5472.CAN-06-2887 [Abstract] [Full Text] [PDF]  

Blockade of Hedgehog Signaling Inhibits Pancreatic Cancer Invasion and Metastases: A New Paradigm for Combination Therapy in Solid Cancers

Georg Feldmann, Surajit Dhara, Volker Fendrich, Djahida Bedja, Robert Beaty, Michael Mullendore, Collins Karikari, Hector Alvarez, Christine Iacobuzio-Donahue, Antonio Jimeno, Kathleen L. Gabrielson, William Matsui, and Anirban Maitra
Cancer Res 2007 67: 2187-2196. doi: 10.1158/0008-5472.CAN-06-3281 [Abstract] [Full Text] [PDF] Supplementary Data  

Computational Modeling and Experimental Evaluation of a Novel Prodrug for Targeting the Extracellular Space of Prostate Tumors

Pavel Pospisil, Ketai Wang, Ayman F. Al Aowad, Lakshmanan K. Iyer, S. James Adelstein, and Amin I. Kassis
Cancer Res 2007 67: 2197-2205. doi: 10.1158/0008-5472.CAN-06-3309 [Abstract] [Full Text] [PDF]  

In vitro Biological Characterization of a Novel, Synthetic Diaryl Pyrazole Resorcinol Class of Heat Shock Protein 90 Inhibitors

Swee Y. Sharp, Kathy Boxall, Martin Rowlands, Chrisostomos Prodromou, S. Mark Roe, Alison Maloney, Marissa Powers, Paul A. Clarke, Gary Box, Sharon Sanderson, Lisa Patterson, Thomas P. Matthews, Kwai-Ming J. Cheung, Karen Ball, Angela Hayes, Florence Raynaud, Richard Marais, Laurence Pearl, Sue Eccles, Wynne Aherne, Edward McDonald, and Paul Workman
Cancer Res 2007 67: 2206-2216. doi: 10.1158/0008-5472.CAN-06-3473 [Abstract] [Full Text] [PDF] Supplementary Data  

Vincristine Induces Dramatic Lysosomal Changes and Sensitizes Cancer Cells to Lysosome-Destabilizing Siramesine

Line Groth-Pedersen, Marie Stampe Ostenfeld, Maria Høyer-Hansen, Jesper Nylandsted, and Marja Jäättelä
Cancer Res 2007 67: 2217-2225. doi: 10.1158/0008-5472.CAN-06-3520 [Abstract] [Full Text] [PDF]  

Identification of Candidate Molecular Markers Predicting Sensitivity in Solid Tumors to Dasatinib: Rationale for Patient Selection

Fei Huang, Karen Reeves, Xia Han, Craig Fairchild, Suso Platero, Tai W. Wong, Francis Lee, Peter Shaw, and Edwin Clark
Cancer Res 2007 67: 2226-2238. doi: 10.1158/0008-5472.CAN-06-3633 [Abstract] [Full Text] [PDF] Supplementary Data  

Phenethyl Isothiocyanate Inhibits Angiogenesis In vitro and Ex vivo

Dong Xiao and Shivendra V. Singh
Cancer Res 2007 67: 2239-2246. doi: 10.1158/0008-5472.CAN-06-3645 [Abstract] [Full Text] [PDF]  

MG-132 Sensitizes TRAIL-Resistant Prostate Cancer Cells by Activating c-Fos/c-Jun Heterodimers and Repressing c-FLIP(L)

Wenhua Li, Xiaoping Zhang, and Aria F. Olumi
Cancer Res 2007 67: 2247-2255. doi: 10.1158/0008-5472.CAN-06-3793 [Abstract] [Full Text] [PDF]  

Histone Deacetylase Inhibitors Synergize p300 Autoacetylation that Regulates Its Transactivation Activity and Complex Formation

Daniel P. Stiehl, Donna M. Fath, Dongming Liang, Yubao Jiang, and Nianli Sang
Cancer Res 2007 67: 2256-2264. doi: 10.1158/0008-5472.CAN-06-3985 [Abstract] [Full Text] [PDF] Supplementary Data  

CD28 Costimulation Overcomes Transforming Growth Factor-ß–Mediated Repression of Proliferation of Redirected Human CD4⁺ and CD8⁺ T Cells in an Antitumor Cell Attack

Heike Koehler, David Kofler, Andreas Hombach, and Hinrich Abken
Cancer Res 2007 67: 2265-2273. doi: 10.1158/0008-5472.CAN-06-2098 [Abstract] [Full Text] [PDF]  

Homeodomain-Interacting Protein Kinase 2 Is the Ionizing Radiation–Activated p53 Serine 46 Kinase and Is Regulated by ATM

Ilka Dauth, Jana Krüger, and Thomas G. Hofmann
Cancer Res 2007 67: 2274-2279. doi: 10.1158/0008-5472.CAN-06-2884 [Abstract] [Full Text] [PDF]  

Targeting the Oligomerization Domain of ETO Interferes with RUNX1/ETO Oncogenic Activity in t(8;21)-Positive Leukemic Cells

Christian Wichmann, Linping Chen, Markus Heinrich, Daniela Baus, Edith Pfitzner, Martin Zörnig, Oliver G. Ottmann, and Manuel Grez
Cancer Res 2007 67: 2280-2289. doi: 10.1158/0008-5472.CAN-06-3360 [Abstract] [Full Text] [PDF] Supplementary Data  

Attenuation of the Glucocorticoid Response during Ad5IL-12 Adenovirus Vector Treatment Enhances Natural Killer Cell–Mediated Killing of MHC Class I–Negative LNCaP Prostate Tumors

Claudia Raja Gabaglia, Yaiza Diaz de Durana, Frank L. Graham, Jack Gauldie, Eli E. Sercarz, and Todd A. Braciak
Cancer Res 2007 67: 2290-2297. doi: 10.1158/0008-5472.CAN-06-3399 [Abstract] [Full Text] [PDF]  

Metabotropic Glutamate Receptor 1 and Glutamate Signaling in Human Melanoma

Jin Namkoong, Seung-Shick Shin, Hwa Jin Lee, Yarí E. Marín, Brian A. Wall, James S. Goydos, and Suzie Chen
Cancer Res 2007 67: 2298-2305. doi: 10.1158/0008-5472.CAN-06-3665 [Abstract] [Full Text] [PDF]  

New Soft Alkylating Agents with Enhanced Cytotoxicity against Cancer Cells Resistant to Chemotherapeutics and Hypoxia

Alexandre Patenaude, Réna G. Deschesnes, Jean L.C. Rousseau, Éric Petitclerc, Jacques Lacroix, Marie-France Côté, and René C.-Gaudreault
Cancer Res 2007 67: 2306-2316. doi: 10.1158/0008-5472.CAN-06-3824 [Abstract] [Full Text] [PDF] Supplementary Data  

Stable Overexpression of Smad7 in Human Melanoma Cells Impairs Bone Metastasis

Delphine Javelaud, Khalid S. Mohammad, Christopher R. McKenna, Pierrick Fournier, Flavie Luciani, Maryla Niewolna, Jocelyne André, Véronique Delmas, Lionel Larue, Theresa A. Guise, and Alain Mauviel
Cancer Res 2007 67: 2317-2324. doi: 10.1158/0008-5472.CAN-06-3950 [Abstract] [Full Text] [PDF] Supplementary Data  

Epidermal Growth Factor Receptor Mutants from Human Lung Cancers Exhibit Enhanced Catalytic Activity and Increased Sensitivity to Gefitinib

Roseann Mulloy, Audrey Ferrand, Youngjoo Kim, Raffaella Sordella, Daphne W. Bell, Daniel A. Haber, Karen S. Anderson, and Jeffrey Settleman
Cancer Res 2007 67: 2325-2330. doi: 10.1158/0008-5472.CAN-06-4293 [Abstract] [Full Text] [PDF] Supplementary Data  

Immunology:

Fractalkine (CX3CL1)– and Interleukin-2–Enriched Neuroblastoma Microenvironment Induces Eradication of Metastases Mediated by T Cells and Natural Killer Cells

Yan Zeng, Nicole Huebener, Stefan Fest, Silke Weixler, Ulrike Schroeder, Gerhard Gaedicke, Rong Xiang, Alexander Schramm, Angelika Eggert, Ralph A. Reisfeld, and Holger N. Lode
Cancer Res 2007 67: 2331-2338. doi: 10.1158/0008-5472.CAN-06-3041 [Abstract] [Full Text] [PDF]  

Tumor Cells Expressing Anti-CD137 scFv Induce a Tumor-Destructive Environment

Yi Yang, Shilin Yang, Zhengmao Ye, Jade Jaffar, Yifeng Zhou, Erin Cutter, Andre Lieber, Ingegerd Hellström, and Karl Erik Hellström
Cancer Res 2007 67: 2339-2344. doi: 10.1158/0008-5472.CAN-06-3593 [Abstract] [Full Text] [PDF]  

Clinical Research:

Overexpression of Dicer in Precursor Lesions of Lung Adenocarcinoma

Simion Chiosea, Elena Jelezcova, Uma Chandran, Jianhua Luo, Geeta Mantha, Robert W. Sobol, and Sanja Dacic
Cancer Res 2007 67: 2345-2350. doi: 10.1158/0008-5472.CAN-06-3533 [Abstract] [Full Text] [PDF]  

A Novel Small-Molecule Inhibitor of Transforming Growth Factor ß Type I Receptor Kinase (SM16) Inhibits Murine Mesothelioma Tumor Growth In vivo and Prevents Tumor Recurrence after Surgical Resection

Eiji Suzuki, Samuel Kim, H.-Kam Cheung, Michael J. Corbley, Xiamei Zhang, Lihong Sun, Feng Shan, Juswinder Singh, Wen-Cherng Lee, Steven M. Albelda, and Leona E. Ling
Cancer Res 2007 67: 2351-2359. doi: 10.1158/0008-5472.CAN-06-2389 [Abstract] [Full Text] [PDF]  

Paternally Inherited Submicroscopic Duplication at 11p15.5 Implicates Insulin-like Growth Factor II in Overgrowth and Wilms' Tumorigenesis

Elizabeth M. Algar, Luke St. Heaps, Artur Darmanian, Vinod Dagar, Dirk Prawitt, Greg B. Peters, and Felicity Collins
Cancer Res 2007 67: 2360-2365. Published Online First February 26, 2007. doi: 10.1158/0008-5472.CAN-06-3383 [Abstract] [Full Text] [PDF]  

Epidemiology and Prevention:

Estrogen Receptors and ß Are Inhibitory Modifiers of Apc-Dependent Tumorigenesis in the Proximal Colon of Min/+ Mice

Nancy L. Cho, Sara H. Javid, Adelaide M. Carothers, Mark Redston, and Monica M. Bertagnolli
Cancer Res 2007 67: 2366-2372. doi: 10.1158/0008-5472.CAN-06-3026 [Abstract] [Full Text] [PDF]  

High Levels of Heat Shock Protein Hsp72 in Cancer Cells Suppress Default Senescence Pathways

Julia A. Yaglom, Vladimir L. Gabai, and Michael Y. Sherman
Cancer Res 2007 67: 2373-2381. doi: 10.1158/0008-5472.CAN-06-3796 [Abstract] [Full Text] [PDF] Supplementary Data  

Infectious Mononucleosis, Childhood Social Environment, and Risk of Hodgkin Lymphoma

Henrik Hjalgrim, Karin Ekström Smedby, Klaus Rostgaard, Daniel Molin, Stephen Hamilton-Dutoit, Ellen T. Chang, Elisabeth Ralfkiaer, Christer Sundström, Hans-Olov Adami, Bengt Glimelius, and Mads Melbye
Cancer Res 2007 67: 2382-2388. doi: 10.1158/0008-5472.CAN-06-3566 [Abstract] [Full Text] [PDF]  

Corrections:

Correction: Genomic Survey of Gliomas

Cancer Res 2007 67: 2389 [Full Text] [PDF]  

Correction: Antagonist of Dishevelled Suppressing Tumor Cell Growth

Cancer Res 2007 67: 2389 [Full Text] [PDF]  

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