Reviews:

Refractoriness to Antivascular Endothelial Growth Factor Treatment: Role of Myeloid Cells

Farbod Shojaei and Napoleone Ferrara
Cancer Res 2008 68: 5501-5504. doi: 10.1158/0008-5472.CAN-08-0925 [Abstract] [Full Text] [PDF]  

Cell Competition and Its Possible Relation to Cancer

Nicholas E. Baker and Wei Li
Cancer Res 2008 68: 5505-5507. doi: 10.1158/0008-5472.CAN-07-6348 [Abstract] [Full Text] [PDF]  

Meeting Reports:

Rethinking Brain Tumors: The Fourth Mouse Models of Human Cancers Consortium Nervous System Tumors Workshop

Karlyne M. Reilly, Joshua B. Rubin, Richard J. Gilbertson, Joel R. Garbow, Martine F. Roussel, and David H. Gutmann
Cancer Res 2008 68: 5508-5511. doi: 10.1158/0008-5472.CAN-08-0703 [Full Text] [PDF] Supplementary Data  

XXIII International Association for Comparative Research on Leukemia and Related Diseases Symposium: from Molecular Pathogenesis to Targeted Therapy in Leukemia and Solid Tumors

Björn Hackanson, Heiko Becker, Tobias Berg, Mascha Binder, Christine Dierks, Jesús Duque-Afonso, Michael D. Lairmore, Henning S. Schäfer, Marc Schnitzler, Robert Zeiser, Uwe Martens, Roland Mertelsmann, and Michael Lübbert
Cancer Res 2008 68: 5512-5518. doi: 10.1158/0008-5472.CAN-07-6859 [Full Text] [PDF] Supplementary Data  

Priority Reports:

A Novel Therapeutic Combination Using PD 0332991 and Bortezomib: Study in the 5T33MM Myeloma Model

Eline Menu, Josefina Garcia, Xiangao Huang, Maurizio Di Liberto, Peter L. Toogood, Isan Chen, Karin Vanderkerken, and Selina Chen-Kiang
Cancer Res 2008 68: 5519-5523. doi: 10.1158/0008-5472.CAN-07-6404 [Abstract] [Full Text] [PDF]  

Novel MEK1 Mutation Identified by Mutational Analysis of Epidermal Growth Factor Receptor Signaling Pathway Genes in Lung Adenocarcinoma

Jenifer L. Marks, Yixuan Gong, Dhananjay Chitale, Ben Golas, Michael D. McLellan, Yumi Kasai, Li Ding, Elaine R. Mardis, Richard K. Wilson, David Solit, Ross Levine, Kathrin Michel, Roman K. Thomas, Valerie W. Rusch, Marc Ladanyi, and William Pao
Cancer Res 2008 68: 5524-5528. doi: 10.1158/0008-5472.CAN-08-0099 [Abstract] [Full Text] [PDF]  

Monitoring Serial Changes in Circulating Human Breast Cancer Cells in Murine Xenograft Models

Jean-Pierre Eliane, Madeline Repollet, Kathryn E. Luker, Martha Brown, James M. Rae, Gabriela Dontu, Anne F. Schott, Max Wicha, Gerald V. Doyle, Daniel F. Hayes, and Gary D. Luker
Cancer Res 2008 68: 5529-5532. doi: 10.1158/0008-5472.CAN-08-0630 [Abstract] [Full Text] [PDF]  

Tissue-Specific Promoters Active in CD44⁺CD24^–/low Breast Cancer Cells

Gerd J. Bauerschmitz, Tuuli Ranki, Lotta Kangasniemi, Camilla Ribacka, Minna Eriksson, Marius Porten, Isabell Herrmann, Ari Ristimäki, Pekka Virkkunen, Maija Tarkkanen, Tanja Hakkarainen, Anna Kanerva, Daniel Rein, Sari Pesonen, and Akseli Hemminki
Cancer Res 2008 68: 5533-5539. doi: 10.1158/0008-5472.CAN-07-5288 [Abstract] [Full Text] [PDF]  

Identification of Hypoxia-Inducible Factor-1 as a Novel Target for miR-17-92 MicroRNA Cluster

Ayumu Taguchi, Kiyoshi Yanagisawa, Masaharu Tanaka, Ke Cao, Yasushi Matsuyama, Hidemi Goto, and Takashi Takahashi
Cancer Res 2008 68: 5540-5545. doi: 10.1158/0008-5472.CAN-07-6460 [Abstract] [Full Text] [PDF] Supplementary Data  

CTCFL/BORIS Is a Methylation-Independent DNA-Binding Protein That Preferentially Binds to the Paternal H19 Differentially Methylated Region

Phuongmai Nguyen, Hengmi Cui, Kheem S. Bisht, Lunching Sun, Krish Patel, Richard S. Lee, Hiroyuki Kugoh, Mitsuo Oshimura, Andrew P. Feinberg, and David Gius
Cancer Res 2008 68: 5546-5551. doi: 10.1158/0008-5472.CAN-08-1005 [Abstract] [Full Text] [PDF] Supplementary Data  

Molecular Biology, Pathobiology, and Genetics:

Targeted Deletion of Rad9 in Mouse Skin Keratinocytes Enhances Genotoxin-Induced Tumor Development

Zhishang Hu, Yuheng Liu, Chunbo Zhang, Yun Zhao, Wei He, Lu Han, Leilei Yang, Kevin M. Hopkins, Xiao Yang, Howard B. Lieberman, and Haiying Hang
Cancer Res 2008 68: 5552-5561. doi: 10.1158/0008-5472.CAN-07-5670 [Abstract] [Full Text] [PDF]  

GSTP1 Promoter Haplotypes Affect DNA Methylation Levels and Promoter Activity in Breast Carcinomas

Jo Anders Rønneberg, Jörg Tost, Hiroko K. Solvang, Grethe I.G. Alnaes, Fredrik E. Johansen, Elen M. Brendeford, Zohar Yakhini, Ivo G. Gut, Per Eystein Lønning, Anne-Lise Børresen-Dale, Odd S. Gabrielsen, and Vessela N. Kristensen
Cancer Res 2008 68: 5562-5571. doi: 10.1158/0008-5472.CAN-07-5828 [Abstract] [Full Text] [PDF] Supplementary Data  

Tripartite Motif Protein 32 Facilitates Cell Growth and Migration via Degradation of Abl-Interactor 2

Satoshi Kano, Naoto Miyajima, Satoshi Fukuda, and Shigetsugu Hatakeyama
Cancer Res 2008 68: 5572-5580. doi: 10.1158/0008-5472.CAN-07-6231 [Abstract] [Full Text] [PDF] Supplementary Data  

A Role for the Cyclin Box in the Ubiquitin-Mediated Degradation of Cyclin G1

Denise M. Piscopo and Philip W. Hinds
Cancer Res 2008 68: 5581-5590. doi: 10.1158/0008-5472.CAN-07-6346 [Abstract] [Full Text] [PDF] Supplementary Data  

PIK3IP1, a Negative Regulator of PI3K, Suppresses the Development of Hepatocellular Carcinoma

Xin He, Zhenqi Zhu, Carla Johnson, John Stoops, Amanda E. Eaker, William Bowen, and Marie C. DeFrances
Cancer Res 2008 68: 5591-5598. doi: 10.1158/0008-5472.CAN-08-0025 [Abstract] [Full Text] [PDF]  

Genomic Alterations Indicate Tumor Origin and Varied Metastatic Potential of Disseminated Cells from Prostate Cancer Patients

Ilona N. Holcomb, Douglas I. Grove, Martin Kinnunen, Cynthia L. Friedman, Ian S. Gallaher, Todd M. Morgan, Cassandra L. Sather, Jeffrey J. Delrow, Peter S. Nelson, Paul H. Lange, William J. Ellis, Lawrence D. True, Janet M. Young, Li Hsu, Barbara J. Trask, and Robert L. Vessella
Cancer Res 2008 68: 5599-5608. doi: 10.1158/0008-5472.CAN-08-0812 [Abstract] [Full Text] [PDF] Supplementary Data  

Thymoquinone Triggers Inactivation of the Stress Response Pathway Sensor CHEK1 and Contributes to Apoptosis in Colorectal Cancer Cells

Hala Gali-Muhtasib, Doerthe Kuester, Christian Mawrin, Khuloud Bajbouj, Antje Diestel, Matthias Ocker, Caroline Habold, Charlotte Foltzer-Jourdainne, Peter Schoenfeld, Brigitte Peters, Mona Diab-Assaf, Ulf Pommrich, Wafica Itani, Hans Lippert, Albert Roessner, and Regine Schneider-Stock
Cancer Res 2008 68: 5609-5618. doi: 10.1158/0008-5472.CAN-08-0884 [Abstract] [Full Text] [PDF] Supplementary Data  

Conditional Loss of Uterine Pten Unfailingly and Rapidly Induces Endometrial Cancer in Mice

Takiko Daikoku, Yasushi Hirota, Susanne Tranguch, Ayesha R. Joshi, Francesco J. DeMayo, John P. Lydon, Lora H. Ellenson, and Sudhansu K. Dey
Cancer Res 2008 68: 5619-5627. doi: 10.1158/0008-5472.CAN-08-1274 [Abstract] [Full Text] [PDF] Supplementary Data  

Cell, Tumor, and Stem Cell Biology:

Cyclin D1b Is Aberrantly Regulated in Response to Therapeutic Challenge and Promotes Resistance to Estrogen Antagonists

Ying Wang, Jeffry L. Dean, Ewan K.A. Millar, Thai Hong Tran, Catriona M. McNeil, Craig J. Burd, Susan M. Henshall, Fransiscus E. Utama, Agnieszka Witkiewicz, Hallgeir Rui, Robert L. Sutherland, Karen E. Knudsen, and Erik S. Knudsen
Cancer Res 2008 68: 5628-5638. doi: 10.1158/0008-5472.CAN-07-3170 [Abstract] [Full Text] [PDF]  

A Special Linker between Macrophage and Hematopoietic Malignant Cells: Membrane Form of Macrophage Colony-Stimulating Factor

Lin Wang, Guo-Guang Zheng, Cui-Hua Ma, Yong-Min Lin, Hai-Yan Zhang, Yuan-Yuan Ma, Jing-Hui Chong, and Ke-Fu Wu
Cancer Res 2008 68: 5639-5647. doi: 10.1158/0008-5472.CAN-07-5804 [Abstract] [Full Text] [PDF]  

SerpinB2 Protection of Retinoblastoma Protein from Calpain Enhances Tumor Cell Survival

Laura Tonnetti, Sarah Netzel-Arnett, Grant A. Darnell, Tamara Hayes, Marguerite S. Buzza, Ian E. Anglin, Andreas Suhrbier, and Toni M. Antalis
Cancer Res 2008 68: 5648-5657. doi: 10.1158/0008-5472.CAN-07-5850 [Abstract] [Full Text] [PDF] Supplementary Data  

The Side Population of Ovarian Cancer Cells Is a Primary Target of IFN- Antitumor Effects

Lidia Moserle, Stefano Indraccolo, Margherita Ghisi, Chiara Frasson, Elena Fortunato, Silvana Canevari, Silvia Miotti, Valeria Tosello, Rita Zamarchi, Alberto Corradin, Sonia Minuzzo, Elisabetta Rossi, Giuseppe Basso, and Alberto Amadori
Cancer Res 2008 68: 5658-5668. doi: 10.1158/0008-5472.CAN-07-6341 [Abstract] [Full Text] [PDF] Supplementary Data  

Identification of c-Cbl as a New Ligase for Insulin-like Growth Factor-I Receptor with Distinct Roles from Mdm2 in Receptor Ubiquitination and Endocytosis

Bita Sehat, Sandra Andersson, Leonard Girnita, and Olle Larsson
Cancer Res 2008 68: 5669-5677. doi: 10.1158/0008-5472.CAN-07-6364 [Abstract] [Full Text] [PDF]  

Vimentin Filaments Support Extension of Tubulin-Based Microtentacles in Detached Breast Tumor Cells

Rebecca A. Whipple, Eric M. Balzer, Edward H. Cho, Michael A. Matrone, Jennifer R. Yoon, and Stuart S. Martin
Cancer Res 2008 68: 5678-5688. doi: 10.1158/0008-5472.CAN-07-6589 [Abstract] [Full Text] [PDF] Supplementary Data  

Overexpression of Vascular Endothelial Growth Factor and the Development of Post-Transplantation Cancer

Aninda Basu, Alan G. Contreras, Dipak Datta, Evelyn Flynn, Liling Zeng, Herbert T. Cohen, David M. Briscoe, and Soumitro Pal
Cancer Res 2008 68: 5689-5698. doi: 10.1158/0008-5472.CAN-07-6603 [Abstract] [Full Text] [PDF] Supplementary Data  

An In vitro Multistep Carcinogenesis Model for Human Cervical Cancer

Mako Narisawa-Saito, Yuki Yoshimatsu, Shin-ichi Ohno, Takashi Yugawa, Nagayasu Egawa, Masatoshi Fujita, Setsuo Hirohashi, and Tohru Kiyono
Cancer Res 2008 68: 5699-5705. doi: 10.1158/0008-5472.CAN-07-6862 [Abstract] [Full Text] [PDF] Supplementary Data  

Temozolomide Preferentially Depletes Cancer Stem Cells in Glioblastoma

Dagmar Beier, Stefanie Röhrl, Deepu R. Pillai, Stefanie Schwarz, Leoni A. Kunz-Schughart, Petra Leukel, Martin Proescholdt, Alexander Brawanski, Ulrich Bogdahn, Ariane Trampe-Kieslich, Bernd Giebel, Jörg Wischhusen, Guido Reifenberger, Peter Hau, and Christoph P. Beier
Cancer Res 2008 68: 5706-5715. doi: 10.1158/0008-5472.CAN-07-6878 [Abstract] [Full Text] [PDF] Supplementary Data  

Jagged-1 and Notch3 Juxtacrine Loop Regulates Ovarian Tumor Growth and Adhesion

Jung-Hye Choi, Joon T. Park, Ben Davidson, Patrice J. Morin, Ie-Ming Shih, and Tian-Li Wang
Cancer Res 2008 68: 5716-5723. doi: 10.1158/0008-5472.CAN-08-0001 [Abstract] [Full Text] [PDF] Supplementary Data  

PAX8 Regulates Telomerase Reverse Transcriptase and Telomerase RNA Component in Glioma

Yu-Jen Chen, Hamish G. Campbell, Anna K. Wiles, Michael R. Eccles, Roger R. Reddel, Antony W. Braithwaite, and Janice A. Royds
Cancer Res 2008 68: 5724-5732. doi: 10.1158/0008-5472.CAN-08-0058 [Abstract] [Full Text] [PDF] Supplementary Data  

Merlin Is a Potent Inhibitor of Glioma Growth

Ying-Ka Ingar Lau, Lucas B. Murray, Sean S. Houshmandi, Yin Xu, David H. Gutmann, and Qin Yu
Cancer Res 2008 68: 5733-5742. doi: 10.1158/0008-5472.CAN-08-0190 [Abstract] [Full Text] [PDF] Supplementary Data  

Identification of a Novel Subgroup of Melanomas with KIT/Cyclin-Dependent Kinase-4 Overexpression

Keiran S.M. Smalley, Rooha Contractor, Thiennga K. Nguyen, Min Xiao, Robin Edwards, Viswanathan Muthusamy, Alastair J. King, Keith T. Flaherty, Marcus Bosenberg, Meenhard Herlyn, and Katherine L. Nathanson
Cancer Res 2008 68: 5743-5752. doi: 10.1158/0008-5472.CAN-08-0235 [Abstract] [Full Text] [PDF] Supplementary Data  

Defining a Chromatin Pattern that Characterizes DNA-Hypermethylated Genes in Colon Cancer Cells

Kelly M. McGarvey, Leander Van Neste, Leslie Cope, Joyce E. Ohm, James G. Herman, Wim Van Criekinge, Kornel E. Schuebel, and Stephen B. Baylin
Cancer Res 2008 68: 5753-5759. doi: 10.1158/0008-5472.CAN-08-0700 [Abstract] [Full Text] [PDF] Supplementary Data  

Pten Deficiency in Melanocytes Results in Resistance to Hair Graying and Susceptibility to Carcinogen-Induced Melanomagenesis

Tae Inoue-Narita, Koichi Hamada, Takehiko Sasaki, Sachiko Hatakeyama, Sachiko Fujita, Kohichi Kawahara, Masato Sasaki, Hiroyuki Kishimoto, Satoshi Eguchi, Itaru Kojima, Friedrich Beermann, Tetsunori Kimura, Masatake Osawa, Satoshi Itami, Tak Wah Mak, Toru Nakano, Motomu Manabe, and Akira Suzuki
Cancer Res 2008 68: 5760-5768. doi: 10.1158/0008-5472.CAN-08-0889 [Abstract] [Full Text] [PDF] Supplementary Data  

Coupling of Mutated Met Variants to DNA Repair via Abl and Rad51

Suganthini S. Ganapathipillai, Michaela Medová, Daniel M. Aebersold, Paul W. Manley, Sylvie Berthou, Bruno Streit, Wieslawa Blank-Liss, Richard H. Greiner, Barbara Rothen-Rutishauser, and Yitzhak Zimmer
Cancer Res 2008 68: 5769-5777. doi: 10.1158/0008-5472.CAN-08-1269 [Abstract] [Full Text] [PDF]  

Low-Dose Radiation Enhances Survivin-Mediated Virotherapy against Malignant Glioma Stem Cells

Suvobroto Nandi, Ilya V. Ulasov, Matthew A. Tyler, Adam Quasar Sugihara, Luciana Molinero, Yu Han, Zeng B. Zhu, and Maciej S. Lesniak
Cancer Res 2008 68: 5778-5784. doi: 10.1158/0008-5472.CAN-07-6441 [Abstract] [Full Text] [PDF]  

Prostate Cancer Induces Bone Metastasis through Wnt-Induced Bone Morphogenetic Protein-Dependent and Independent Mechanisms

Jinlu Dai, Christopher L. Hall, June Escara-Wilke, Atsushi Mizokami, Jill M. Keller, and Evan T. Keller
Cancer Res 2008 68: 5785-5794. doi: 10.1158/0008-5472.CAN-07-6541 [Abstract] [Full Text] [PDF] Supplementary Data  

Regulation of the Adenomatous Polyposis Coli Gene by the miR-135 Family in Colorectal Cancer

Remco Nagel, Carlos le Sage, Begoña Diosdado, Maike van der Waal, Joachim A.F. Oude Vrielink, Anne Bolijn, Gerrit A. Meijer, and Reuven Agami
Cancer Res 2008 68: 5795-5802. doi: 10.1158/0008-5472.CAN-08-0951 [Abstract] [Full Text] [PDF] Supplementary Data  

Tumor Microenvironment:

Cathepsin G Enhances Mammary Tumor–Induced Osteolysis by Generating Soluble Receptor Activator of Nuclear Factor-B Ligand

Thomas J. Wilson, Kalyan C. Nannuru, Mitsuru Futakuchi, Anguraj Sadanandam, and Rakesh K. Singh
Cancer Res 2008 68: 5803-5811. doi: 10.1158/0008-5472.CAN-07-5889 [Abstract] [Full Text] [PDF]  

The Pervasive Presence of Fluctuating Oxygenation in Tumors

Laura I. Cárdenas-Navia, Daniel Mace, Rachel A. Richardson, David F. Wilson, Siqing Shan, and Mark W. Dewhirst
Cancer Res 2008 68: 5812-5819. doi: 10.1158/0008-5472.CAN-07-6387 [Abstract] [Full Text] [PDF] Supplementary Data  

Extracellular Redox State Regulates Features Associated with Prostate Cancer Cell Invasion

Luksana Chaiswing, Weixiong Zhong, Joseph J. Cullen, Larry W. Oberley, and Terry D. Oberley
Cancer Res 2008 68: 5820-5826. doi: 10.1158/0008-5472.CAN-08-0162 [Abstract] [Full Text] [PDF] Supplementary Data  

Experimental Therapeutics, Molecular Targets, and Chemical Biology:

Hsp90 Inhibition Suppresses Mutant EGFR-T790M Signaling and Overcomes Kinase Inhibitor Resistance

Takeshi Shimamura, Danan Li, Hongbin Ji, Henry J. Haringsma, Elizabeth Liniker, Christa L. Borgman, April M. Lowell, Yuko Minami, Kate McNamara, Samanthi A. Perera, Sara Zaghlul, Roman K. Thomas, Heidi Greulich, Susumu Kobayashi, Lucian R. Chirieac, Robert F. Padera, Shigeto Kubo, Masaya Takahashi, Daniel G. Tenen, Matthew Meyerson, Kwok-Kin Wong, and Geoffrey I. Shapiro
Cancer Res 2008 68: 5827-5838. doi: 10.1158/0008-5472.CAN-07-5428 [Abstract] [Full Text] [PDF] Supplementary Data  

Activation of Platelet-Activating Factor Receptor and Pleiotropic Effects on Tyrosine Phospho-EGFR/Src/FAK/Paxillin in Ovarian Cancer

Margarita Aponte, Wei Jiang, Montaha Lakkis, Ming-Jiang Li, Dale Edwards, Lina Albitar, Allison Vitonis, Samuel C. Mok, Daniel W. Cramer, and Bin Ye
Cancer Res 2008 68: 5839-5848. doi: 10.1158/0008-5472.CAN-07-5771 [Abstract] [Full Text] [PDF]  

Clinical and Biological Significance of Tissue Transglutaminase in Ovarian Carcinoma

Jee Young Hwang, Lingegowda S. Mangala, Jansina Y. Fok, Yvonne G. Lin, William M. Merritt, Whitney A. Spannuth, Alpa M. Nick, Derek J. Fiterman, Pablo E. Vivas-Mejia, Michael T. Deavers, Robert L. Coleman, Gabriel Lopez-Berestein, Kapil Mehta, and Anil K. Sood
Cancer Res 2008 68: 5849-5858. doi: 10.1158/0008-5472.CAN-07-6130 [Abstract] [Full Text] [PDF] Supplementary Data  

Inhibition of Glycogen Synthase Kinase 3β Attenuates Neurocognitive Dysfunction Resulting from Cranial Irradiation

Dinesh K. Thotala, Dennis E. Hallahan, and Eugenia M. Yazlovitskaya
Cancer Res 2008 68: 5859-5868. doi: 10.1158/0008-5472.CAN-07-6327 [Abstract] [Full Text] [PDF] Supplementary Data  

Human Endogenous Retrovirus K Triggers an Antigen-Specific Immune Response in Breast Cancer Patients

Feng Wang-Johanning, Laszlo Radvanyi, Kiera Rycaj, Joshua B. Plummer, Peisha Yan, K. Jagannadha Sastry, Chandrika J. Piyathilake, Kelly K. Hunt, and Gary L. Johanning
Cancer Res 2008 68: 5869-5877. doi: 10.1158/0008-5472.CAN-07-6838 [Abstract] [Full Text] [PDF] Supplementary Data  

A Central Role for HER3 in HER2-Amplified Breast Cancer: Implications for Targeted Therapy

Si Tuen Lee-Hoeflich, Lisa Crocker, Evelyn Yao, Thinh Pham, Xander Munroe, Klaus P. Hoeflich, Mark X. Sliwkowski, and Howard M. Stern
Cancer Res 2008 68: 5878-5887. doi: 10.1158/0008-5472.CAN-08-0380 [Abstract] [Full Text] [PDF] Supplementary Data  

Atypical Protein Kinase C Expression and Aurothiomalate Sensitivity in Human Lung Cancer Cells

Roderick P. Regala, E. Aubrey Thompson, and Alan P. Fields
Cancer Res 2008 68: 5888-5895. doi: 10.1158/0008-5472.CAN-08-0438 [Abstract] [Full Text] [PDF] Supplementary Data  

Macrophage Depletion Combined with Anticoagulant Therapy Increases Therapeutic Window of Systemic Treatment with Oncolytic Adenovirus

Elena V. Shashkova, Konstantin Doronin, Julien S. Senac, and Michael A. Barry
Cancer Res 2008 68: 5896-5904. doi: 10.1158/0008-5472.CAN-08-0488 [Abstract] [Full Text] [PDF]  

The Novel Angiogenic Inhibitor, Angiocidin, Induces Differentiation of Monocytes to Macrophages

Anita Gaurnier-Hausser, Vicki L. Rothman, Svetoslav Dimitrov, and George P. Tuszynski
Cancer Res 2008 68: 5905-5914. doi: 10.1158/0008-5472.CAN-07-6179 [Abstract] [Full Text] [PDF] Supplementary Data  

Class I PI3 Kinase Inhibition by the Pyridinylfuranopyrimidine Inhibitor PI-103 Enhances Tumor Radiosensitivity

Remko Prevo, Eric Deutsch, Oliver Sampson, Julie Diplexcito, Keith Cengel, Jane Harper, Peter O'Neill, W. Gillies McKenna, Sonal Patel, and Eric J. Bernhard
Cancer Res 2008 68: 5915-5923. doi: 10.1158/0008-5472.CAN-08-0757 [Abstract] [Full Text] [PDF] Supplementary Data  

Systems Biology and Emerging Technologies:

Cell Lineage Analysis of a Mouse Tumor

Dan Frumkin, Adam Wasserstrom, Shalev Itzkovitz, Tomer Stern, Alon Harmelin, Raya Eilam, Gideon Rechavi, and Ehud Shapiro
Cancer Res 2008 68: 5924-5931. doi: 10.1158/0008-5472.CAN-07-6216 [Abstract] [Full Text] [PDF] Supplementary Data  

Noninvasive Assessment of E2F-1–Mediated Transcriptional Regulation In vivo

Parisa Monfared, Alexandra Winkeler, Markus Klein, Hongfeng Li, Anke Klose, Marianna Hoesel, Yannic Waerzeggers, Sigrun Korsching, and Andreas H. Jacobs
Cancer Res 2008 68: 5932-5940. doi: 10.1158/0008-5472.CAN-07-6373 [Abstract] [Full Text] [PDF]  

New Insights into Tumor Microstructure Using Temporal Diffusion Spectroscopy

Daniel C. Colvin, Thomas E. Yankeelov, Mark D. Does, Zoe Yue, Chad Quarles, and John C. Gore
Cancer Res 2008 68: 5941-5947. doi: 10.1158/0008-5472.CAN-08-0832 [Abstract] [Full Text] [PDF]  

Immunology:

Regulatory T Cell–Resistant CD8⁺ T Cells Induced by Glucocorticoid-Induced Tumor Necrosis Factor Receptor Signaling

Hiroyoshi Nishikawa, Takuma Kato, Michiko Hirayama, Yuki Orito, Eiichi Sato, Naozumi Harada, Sacha Gnjatic, Lloyd J. Old, and Hiroshi Shiku
Cancer Res 2008 68: 5948-5954. doi: 10.1158/0008-5472.CAN-07-5839 [Abstract] [Full Text] [PDF] Supplementary Data  

Vaccination Elicits Correlated Immune and Clinical Responses in Glioblastoma Multiforme Patients

Christopher J. Wheeler, Keith L. Black, Gentao Liu, Mia Mazer, Xiao-xue Zhang, Samuel Pepkowitz, Dennis Goldfinger, Hiushan Ng, Dwain Irvin, and John S. Yu
Cancer Res 2008 68: 5955-5964. doi: 10.1158/0008-5472.CAN-07-5973 [Abstract] [Full Text] [PDF]  

Recruitment and Activation of Natural Killer Cells In vitro by a Human Dendritic Cell Vaccine

Karin Gustafsson, Madeleine Ingelsten, Linda Bergqvist, Jenny Nyström, Bengt Andersson, and Alex Karlsson-Parra
Cancer Res 2008 68: 5965-5971. doi: 10.1158/0008-5472.CAN-07-6494 [Abstract] [Full Text] [PDF]  

Ability of Mature Dendritic Cells to Interact with Regulatory T Cells Is Imprinted during Maturation

Ravikumar Muthuswamy, Julie Urban, Je-Jung Lee, Todd A. Reinhart, David Bartlett, and Pawel Kalinski
Cancer Res 2008 68: 5972-5978. doi: 10.1158/0008-5472.CAN-07-6818 [Abstract] [Full Text] [PDF] Supplementary Data  

Modulation of CD59 Expression by Restrictive Silencer Factor–Derived Peptides in Cancer Immunotherapy for Neuroblastoma

Rossen M. Donev, Lisa C. Gray, Baalasubramanian Sivasankar, Timothy R. Hughes, Carmen W. van den Berg, and B. Paul Morgan
Cancer Res 2008 68: 5979-5987. doi: 10.1158/0008-5472.CAN-07-6828 [Abstract] [Full Text] [PDF]  

Clinical Research:

Hepatitis B Virus–Associated Multistep Hepatocarcinogenesis: A Stepwise Increase in Allelic Alterations

Joyce Man-Fong Lee, Chun-Ming Wong, and Irene Oi-Lin Ng
Cancer Res 2008 68: 5988-5996. doi: 10.1158/0008-5472.CAN-08-0905 [Abstract] [Full Text] [PDF] Supplementary Data  

Epidemiology:

Breast Cancer Risk Reduction and Membrane-Bound Catechol O-Methyltransferase Genetic Polymorphisms

Yuan Ji, Janet Olson, Jianping Zhang, Michelle Hildebrandt, Liewei Wang, James Ingle, Zachary Fredericksen, Thomas Sellers, William Miller, J. Michael Dixon, Hiltrud Brauch, Michel Eichelbaum, Christina Justenhoven, Ute Hamann, Yon Ko, Thomas Brüning, Jenny Chang-Claude, Shan Wang-Gohrke, Daniel Schaid, and Richard Weinshilboum
Cancer Res 2008 68: 5997-6005. doi: 10.1158/0008-5472.CAN-08-0043 [Abstract] [Full Text] [PDF] Supplementary Data  

Presence of a TA Haplotype in the APC Gene Containing the Common 1822 Polymorphism and Colorectal Adenoma

Jan B. Egan, Elizabeth T. Jacobs, María Elena Martínez, Eugene W. Gerner, Peter W. Jurutka, and Patricia A. Thompson
Cancer Res 2008 68: 6006-6013. doi: 10.1158/0008-5472.CAN-08-1084 [Abstract] [Full Text] [PDF] Supplementary Data  

PTEN Expression in Endometrial Biopsies as a Marker of Progression to Endometrial Carcinoma

James V. Lacey, Jr., George L. Mutter, Brigitte M. Ronnett, Olga B. Ioffe, Máire A. Duggan, Brenda B. Rush, Andrew G. Glass, Douglas A. Richesson, Nilanjan Chatterjee, Bryan Langholz, and Mark E. Sherman
Cancer Res 2008 68: 6014-6020. doi: 10.1158/0008-5472.CAN-08-1154 [Abstract] [Full Text] [PDF]  

Prevention:

Myricetin Suppresses UVB-Induced Skin Cancer by Targeting Fyn

Sung Keun Jung, Ki Won Lee, Sanguine Byun, Nam Joo Kang, Sung Hwan Lim, Yong-Seok Heo, Ann M. Bode, G. Tim Bowden, Hyong Joo Lee, and Zigang Dong
Cancer Res 2008 68: 6021-6029. doi: 10.1158/0008-5472.CAN-08-0899 [Abstract] [Full Text] [PDF]  

Corrections:

Correction: Pan PI3K Inhibitor Prodrug for Cancer Therapy

Cancer Res 2008 68: 6030. doi: 10.1158/0008-5472.CAN-68-14-COR1 [Full Text] [PDF]  

Correction: Hypermethylation of Wnt Antagonist SOX17 in Colorectal Cancer

Cancer Res 2008 68: 6030. doi: 10.1158/0008-5472.CAN-68-14-COR2 [Full Text] [PDF]  

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