AACR Centennial Series:

The History of Tumor Virology

Ronald T. Javier and Janet S. Butel
Cancer Res 2008 68: 7693-7706. doi: 10.1158/0008-5472.CAN-08-3301 [Abstract] [Full Text] [PDF]  

REVIEWS:

Pancreatic Stellate Cells and Pancreatic Cancer Cells: An Unholy Alliance

Alain Vonlaufen, Phoebe A. Phillips, Zhihong Xu, David Goldstein, Romano C. Pirola, Jeremy S. Wilson, and Minoti V. Apte
Cancer Res 2008 68: 7707-7710. doi: 10.1158/0008-5472.CAN-08-1132 [Abstract] [Full Text] [PDF]  

Priority Reports:

The Mammary Progenitor Marker CD61/β3 Integrin Identifies Cancer Stem Cells in Mouse Models of Mammary Tumorigenesis

François Vaillant, Marie-Liesse Asselin-Labat, Mark Shackleton, Natasha C. Forrest, Geoffrey J. Lindeman, and Jane E. Visvader
Cancer Res 2008 68: 7711-7717. doi: 10.1158/0008-5472.CAN-08-1949 [Abstract] [Full Text] [PDF] Supplementary Data  

Mutations in the Focal Adhesion Targeting Region of Deleted in Liver Cancer-1 Attenuate Their Expression and Function

Yi-Chun Liao, Yi-Ping Shih, and Su Hao Lo
Cancer Res 2008 68: 7718-7722. doi: 10.1158/0008-5472.CAN-08-2042 [Abstract] [Full Text] [PDF]  

SCL/TAL1 Interrupting Locus Derepresses GLI1 from the Negative Control of Suppressor-of-Fused in Pancreatic Cancer Cell

Kenji Kasai, Shingo Inaguma, Akiko Yoneyama, Kazuhiro Yoshikawa, and Hiroshi Ikeda
Cancer Res 2008 68: 7723-7729. doi: 10.1158/0008-5472.CAN-07-6661 [Abstract] [Full Text] [PDF] Supplementary Data  

Identification of Transformation-Related Pathways in a Breast Epithelial Cell Model Using a Ribonomics Approach

Krystyna Mazan-Mamczarz, Patrick R. Hagner, Bojie Dai, William H. Wood, Yongqing Zhang, Kevin G. Becker, Zhenqui Liu, and Ronald B. Gartenhaus
Cancer Res 2008 68: 7730-7735. doi: 10.1158/0008-5472.CAN-08-2393 [Abstract] [Full Text] [PDF] Supplementary Data  

Activation of Signal Transducer and Activator of Transcription 3 through a Phosphomimetic Serine 727 Promotes Prostate Tumorigenesis Independent of Tyrosine 705 Phosphorylation

Haiyan R. Qin, Han-Jong Kim, Joon-Young Kim, Elaine M. Hurt, George J. Klarmann, Brian T. Kawasaki, Maria A. Duhagon Serrat, and William L. Farrar
Cancer Res 2008 68: 7736-7741. doi: 10.1158/0008-5472.CAN-08-1125 [Abstract] [Full Text] [PDF] Supplementary Data  

Cell, Tumor, and Stem Cell Biology:

The Polycomb Gene Product BMI1 Contributes to the Maintenance of Tumor-Initiating Side Population Cells in Hepatocellular Carcinoma

Tetsuhiro Chiba, Satoru Miyagi, Atsunori Saraya, Ryutaro Aoki, Atsuyoshi Seki, Yohei Morita, Yutaka Yonemitsu, Osamu Yokosuka, Hideki Taniguchi, Hiromitsu Nakauchi, and Atsushi Iwama
Cancer Res 2008 68: 7742-7749. doi: 10.1158/0008-5472.CAN-07-5882 [Abstract] [Full Text] [PDF] Supplementary Data  

Prostaglandin E₂ Regulates Tumor Angiogenesis in Prostate Cancer

Shalini Jain, Goutam Chakraborty, Remya Raja, Smita Kale, and Gopal C. Kundu
Cancer Res 2008 68: 7750-7759. doi: 10.1158/0008-5472.CAN-07-6689 [Abstract] [Full Text] [PDF] Supplementary Data  

Ectopic Expression of P-Cadherin Correlates with Promoter Hypomethylation Early in Colorectal Carcinogenesis and Enhanced Intestinal Crypt Fission In vivo

Anita Milicic, Lea-Anne Harrison, Robert A. Goodlad, Robert G. Hardy, Anna M. Nicholson, Michal Presz, Oliver Sieber, Sonia Santander, James H. Pringle, Nikki Mandir, Philip East, Jolanta Obszynska, Scott Sanders, Elena Piazuelo, Jacqui Shaw, Rebecca Harrison, Ian P. Tomlinson, Stuart A.C. McDonald, Nicholas A. Wright, and Janusz A.Z. Jankowski
Cancer Res 2008 68: 7760-7768. doi: 10.1158/0008-5472.CAN-08-0020 [Abstract] [Full Text] [PDF] Supplementary Data  

Prolyl Isomerase Cyclophilin A Regulation of Janus-Activated Kinase 2 and the Progression of Human Breast Cancer

Jiamao Zheng, Jennifer E. Koblinski, Laura V. Dutson, Yvonne B. Feeney, and Charles V. Clevenger
Cancer Res 2008 68: 7769-7778. doi: 10.1158/0008-5472.CAN-08-0639 [Abstract] [Full Text] [PDF] Supplementary Data  

Breast Tumor Kinase Phosphorylates p190RhoGAP to Regulate Rho and Ras and Promote Breast Carcinoma Growth, Migration, and Invasion

Che-Hung Shen, Hsin-Yi Chen, Ming-Shien Lin, Fang-Yen Li, Cheng-Chi Chang, Min-Liang Kuo, Jeffrey Settleman, and Ruey-Hwa Chen
Cancer Res 2008 68: 7779-7787. doi: 10.1158/0008-5472.CAN-08-0997 [Abstract] [Full Text] [PDF] Supplementary Data  

Brn-2 Represses Microphthalmia-Associated Transcription Factor Expression and Marks a Distinct Subpopulation of Microphthalmia-Associated Transcription Factor–Negative Melanoma Cells

Jane Goodall, Suzanne Carreira, Laurence Denat, Dominique Kobi, Irwin Davidson, Paolo Nuciforo, Richard A. Sturm, Lionel Larue, and Colin R. Goding
Cancer Res 2008 68: 7788-7794. doi: 10.1158/0008-5472.CAN-08-1053 [Abstract] [Full Text] [PDF]  

Runx2 Transcriptional Activation of Indian Hedgehog and a Downstream Bone Metastatic Pathway in Breast Cancer Cells

Jitesh Pratap, John J. Wixted, Tripti Gaur, Sayyed K. Zaidi, Jason Dobson, Karthiga Devi Gokul, Sadiq Hussain, Andre J. van Wijnen, Janet L. Stein, Gary S. Stein, and Jane B. Lian
Cancer Res 2008 68: 7795-7802. doi: 10.1158/0008-5472.CAN-08-1078 [Abstract] [Full Text] [PDF] Supplementary Data  

Dietary Induction of Colonic Tumors in a Mouse Model of Sporadic Colon Cancer

Kan Yang, Naoto Kurihara, Kunhua Fan, Harold Newmark, Basil Rigas, Laura Bancroft, Georgia Corner, Elayne Livote, Martin Lesser, Winfried Edelmann, Anna Velcich, Martin Lipkin, and Leonard Augenlicht
Cancer Res 2008 68: 7803-7810. doi: 10.1158/0008-5472.CAN-08-1209 [Abstract] [Full Text] [PDF] Supplementary Data  

Anterior Gradient 2 Is Expressed and Secreted during the Development of Pancreatic Cancer and Promotes Cancer Cell Survival

Vijaya Ramachandran, Thiruvengadam Arumugam, Huamin Wang, and Craig D. Logsdon
Cancer Res 2008 68: 7811-7818. doi: 10.1158/0008-5472.CAN-08-1320 [Abstract] [Full Text] [PDF] Supplementary Data  

SLITs Suppress Tumor Growth In vivo by Silencing Sdf1/Cxcr4 within Breast Epithelium

Rebecca Marlow, Phyllis Strickland, Ji Shin Lee, Xinyan Wu, Milana PeBenito, Mikhail Binnewies, Elizabeth K. Le, Angel Moran, Hector Macias, Robert D. Cardiff, Saraswati Sukumar, and Lindsay Hinck
Cancer Res 2008 68: 7819-7827. doi: 10.1158/0008-5472.CAN-08-1357 [Abstract] [Full Text] [PDF] Supplementary Data  

Suppression of Prostate Cancer Nodal and Systemic Metastasis by Blockade of the Lymphangiogenic Axis

Jeremy B. Burton, Saul J. Priceman, James L. Sung, Ebba Brakenhielm, Dong Sung An, Bronislaw Pytowski, Kari Alitalo, and Lily Wu
Cancer Res 2008 68: 7828-7837. doi: 10.1158/0008-5472.CAN-08-1488 [Abstract] [Full Text] [PDF] Supplementary Data  

Hepatocyte Growth Factor and Sonic Hedgehog Expression in Cerebellar Neural Progenitor Cells Costimulate Medulloblastoma Initiation and Growth

Mandy J. Binning, Toba Niazi, Carolyn A. Pedone, Bachchu Lal, Charles G. Eberhart, K. Jin Kim, John Laterra, and Daniel W. Fults
Cancer Res 2008 68: 7838-7845. doi: 10.1158/0008-5472.CAN-08-1899 [Abstract] [Full Text] [PDF] Supplementary Data  

A Double-Negative Feedback Loop between ZEB1-SIP1 and the microRNA-200 Family Regulates Epithelial-Mesenchymal Transition

Cameron P. Bracken, Philip A. Gregory, Natasha Kolesnikoff, Andrew G. Bert, Jun Wang, M. Frances Shannon, and Gregory J. Goodall
Cancer Res 2008 68: 7846-7854. doi: 10.1158/0008-5472.CAN-08-1942 [Abstract] [Full Text] [PDF]  

Regulation of Estrogenic Effects by Beclin 1 in Breast Cancer Cells

Shali John, Irina Nayvelt, Hui-Chen Hsu, PingAr Yang, Wensheng Liu, Gokul M. Das, Thresia Thomas, and T.J. Thomas
Cancer Res 2008 68: 7855-7863. doi: 10.1158/0008-5472.CAN-07-5875 [Abstract] [Full Text] [PDF]  

Senescence-Associated Exosome Release from Human Prostate Cancer Cells

Brian D. Lehmann, Matthew S. Paine, Adam M. Brooks, James A. McCubrey, Randall H. Renegar, Rong Wang, and David M. Terrian
Cancer Res 2008 68: 7864-7871. doi: 10.1158/0008-5472.CAN-07-6538 [Abstract] [Full Text] [PDF]  

Tbx3 Represses E-Cadherin Expression and Enhances Melanoma Invasiveness

Mercedes Rodriguez, Ewa Aladowicz, Luisa Lanfrancone, and Colin R. Goding
Cancer Res 2008 68: 7872-7881. doi: 10.1158/0008-5472.CAN-08-0301 [Abstract] [Full Text] [PDF]  

Cell Cycle–Dependent Variation of a CD133 Epitope in Human Embryonic Stem Cell, Colon Cancer, and Melanoma Cell Lines

Marie Jaksch, Jorge Múnera, Ruchi Bajpai, Alexey Terskikh, and Robert G. Oshima
Cancer Res 2008 68: 7882-7886. doi: 10.1158/0008-5472.CAN-08-0723 [Abstract] [Full Text] [PDF] Supplementary Data  

Dual Roles for Coactivator Activator and its Counterbalancing Isoform Coactivator Modulator in Human Kidney Cell Tumorigenesis

Yun Kyoung Kang, Rachel Schiff, Lan Ko, Tao Wang, Sophia Y. Tsai, Ming-Jer Tsai, and Bert W. O'Malley
Cancer Res 2008 68: 7887-7896. doi: 10.1158/0008-5472.CAN-08-1734 [Abstract] [Full Text] [PDF] Supplementary Data  

Endocrinology:

Glucagon-like Peptide-2 Does Not Modify the Growth or Survival of Murine or Human Intestinal Tumor Cells

Jacqueline A. Koehler, Will Harper, Maja Barnard, Bernardo Yusta, and Daniel J. Drucker
Cancer Res 2008 68: 7897-7904. doi: 10.1158/0008-5472.CAN-08-0029 [Abstract] [Full Text] [PDF] Supplementary Data  

Experimental Therapeutics, Molecular Targets, and Chemical Biology:

Lapatinib (Tykerb, GW572016) Reverses Multidrug Resistance in Cancer Cells by Inhibiting the Activity of ATP-Binding Cassette Subfamily B Member 1 and G Member 2

Chun-ling Dai, Amit K. Tiwari, Chung-Pu Wu, Xiao-dong Su, Si-Rong Wang, Dong-geng Liu, Charles R. Ashby, Jr., Yan Huang, Robert W. Robey, Yong-ju Liang, Li-ming Chen, Cheng-Jun Shi, Suresh V. Ambudkar, Zhe-Sheng Chen, and Li-wu Fu
Cancer Res 2008 68: 7905-7914. doi: 10.1158/0008-5472.CAN-08-0499 [Abstract] [Full Text] [PDF] Supplementary DataSupplementary Data  

Disruption of NAD(P)H:Quinone Oxidoreductase 1 Gene in Mice Leads to Radiation-Induced Myeloproliferative Disease

Karim Iskander, Roberto J. Barrios, and Anil K. Jaiswal
Cancer Res 2008 68: 7915-7922. doi: 10.1158/0008-5472.CAN-08-0766 [Abstract] [Full Text] [PDF]  

Nuclear Survivin Abrogates Multiple Cell Cycle Checkpoints and Enhances Viral Oncolysis

Claire M. Connell, Sally P. Wheatley, and Iain A. McNeish
Cancer Res 2008 68: 7923-7931. doi: 10.1158/0008-5472.CAN-08-0817 [Abstract] [Full Text] [PDF] Supplementary Data  

Validation of the p21-Activated Kinases as Targets for Inhibition in Neurofibromatosis Type 2

Chunling Yi, Erik W. Wilker, Michael B. Yaffe, Anat Stemmer-Rachamimov, and Joseph L. Kissil
Cancer Res 2008 68: 7932-7937. doi: 10.1158/0008-5472.CAN-08-0866 [Abstract] [Full Text] [PDF] Supplementary Data  

The RNA Helicase p68 Is a Novel Androgen Receptor Coactivator Involved in Splicing and Is Overexpressed in Prostate Cancer

Emma L. Clark, Anne Coulson, Caroline Dalgliesh, Prabhakar Rajan, Samantha M. Nicol, Stewart Fleming, Rakesh Heer, Luke Gaughan, Hing Y. Leung, David J. Elliott, Frances V. Fuller-Pace, and Craig N. Robson
Cancer Res 2008 68: 7938-7946. doi: 10.1158/0008-5472.CAN-08-0932 [Abstract] [Full Text] [PDF]  

ATM and the Mre11-Rad50-Nbs1 Complex Respond to Nucleoside Analogue–Induced Stalled Replication Forks and Contribute to Drug Resistance

Brett Ewald, Deepa Sampath, and William Plunkett
Cancer Res 2008 68: 7947-7955. doi: 10.1158/0008-5472.CAN-08-0971 [Abstract] [Full Text] [PDF]  

Targeting XIAP Bypasses Bcl-2–Mediated Resistance to TRAIL and Cooperates with TRAIL to Suppress Pancreatic Cancer Growth In vitro and In vivo

Meike Vogler, Henning Walczak, Dominic Stadel, Tobias L. Haas, Felicitas Genze, Marjana Jovanovic, Jürgen E. Gschwend, Thomas Simmet, Klaus-Michael Debatin, and Simone Fulda
Cancer Res 2008 68: 7956-7965. doi: 10.1158/0008-5472.CAN-08-1296 [Abstract] [Full Text] [PDF] Supplementary Data  

Autophagy: A Novel Mechanism of Synergistic Cytotoxicity between Doxorubicin and Roscovitine in a Sarcoma Model

Laura A. Lambert, Na Qiao, Kelly K. Hunt, Donald H. Lambert, Gordon B. Mills, Laurent Meijer, and Khandan Keyomarsi
Cancer Res 2008 68: 7966-7974. doi: 10.1158/0008-5472.CAN-08-1333 [Abstract] [Full Text] [PDF]  

RNAi-Mediated Silencing of Nuclear Factor Erythroid-2–Related Factor 2 Gene Expression in Non–Small Cell Lung Cancer Inhibits Tumor Growth and Increases Efficacy of Chemotherapy

Anju Singh, Swetlana Boldin-Adamsky, Rajesh K. Thimmulappa, Srikanta K. Rath, Hagit Ashush, Jonathan Coulter, Amanda Blackford, Steven N. Goodman, Fred Bunz, Walter H. Watson, Edward Gabrielson, Elena Feinstein, and Shyam Biswal
Cancer Res 2008 68: 7975-7984. doi: 10.1158/0008-5472.CAN-08-1401 [Abstract] [Full Text] [PDF] Supplementary Data  

Alteration of the Mitochondrial Apoptotic Pathway Is Key to Acquired Paclitaxel Resistance and Can Be Reversed by ABT-737

Ozgur Kutuk and Anthony Letai
Cancer Res 2008 68: 7985-7994. doi: 10.1158/0008-5472.CAN-08-1418 [Abstract] [Full Text] [PDF]  

Optimized Clostridium-Directed Enzyme Prodrug Therapy Improves the Antitumor Activity of the Novel DNA Cross-Linking Agent PR-104

Shie-Chau Liu, G-One Ahn, Mitomu Kioi, Mary-Jo Dorie, Adam V. Patterson, and J. Martin Brown
Cancer Res 2008 68: 7995-8003. doi: 10.1158/0008-5472.CAN-08-1698 [Abstract] [Full Text] [PDF] Supplementary Data  

Heterogeneity of Receptor Function in Colon Carcinoma Cells Determined by Cross-talk between Type I Insulin-like Growth Factor Receptor and Epidermal Growth Factor Receptor

Yi Peter Hu, Sandip B. Patil, Michelle Panasiewicz, Wenhui Li, Jennie Hauser, Lisa E. Humphrey, and Michael G. Brattain
Cancer Res 2008 68: 8004-8013. doi: 10.1158/0008-5472.CAN-08-0280 [Abstract] [Full Text] [PDF]  

Evaluation of Cancer Tests of 1,3-Butadiene Using Internal Dose, Genotoxic Potency, and a Multiplicative Risk Model

Charlotta Fred, Margareta Törnqvist, and Fredrik Granath
Cancer Res 2008 68: 8014-8021. doi: 10.1158/0008-5472.CAN-08-0334 [Abstract] [Full Text] [PDF]  

NVP-BEZ235, a Dual PI3K/mTOR Inhibitor, Prevents PI3K Signaling and Inhibits the Growth of Cancer Cells with Activating PI3K Mutations

Violeta Serra, Ben Markman, Maurizio Scaltriti, Pieter J.A. Eichhorn, Vanesa Valero, Marta Guzman, Maria Luisa Botero, Elisabeth Llonch, Francesco Atzori, Serena Di Cosimo, Michel Maira, Carlos Garcia-Echeverria, Josep Lluis Parra, Joaquin Arribas, and José Baselga
Cancer Res 2008 68: 8022-8030. doi: 10.1158/0008-5472.CAN-08-1385 [Abstract] [Full Text] [PDF] Supplementary Data  

Vitamin C Antagonizes the Cytotoxic Effects of Antineoplastic Drugs

Mark L. Heaney, Jeffrey R. Gardner, Nicos Karasavvas, David W. Golde, David A. Scheinberg, Emily A. Smith, and Owen A. O'Connor
Cancer Res 2008 68: 8031-8038. doi: 10.1158/0008-5472.CAN-08-1490 [Abstract] [Full Text] [PDF] Supplementary Data  

Addiction to Elevated Insulin-like Growth Factor I Receptor and Initial Modulation of the AKT Pathway Define the Responsiveness of Rhabdomyosarcoma to the Targeting Antibody

Liang Cao, Yunkai Yu, Isaac Darko, Duane Currier, Linnia H. Mayeenuddin, Xiaolin Wan, Chand Khanna, and Lee J. Helman
Cancer Res 2008 68: 8039-8048. doi: 10.1158/0008-5472.CAN-08-1712 [Abstract] [Full Text] [PDF]  

Potent In vitro and In vivo Activity of an Fc-Engineered Anti-CD19 Monoclonal Antibody against Lymphoma and Leukemia

Holly M. Horton, Matthew J. Bernett, Erik Pong, Matthias Peipp, Sher Karki, Seung Y. Chu, John O. Richards, Igor Vostiar, Patrick F. Joyce, Roland Repp, John R. Desjarlais, and Eugene A. Zhukovsky
Cancer Res 2008 68: 8049-8057. doi: 10.1158/0008-5472.CAN-08-2268 [Abstract] [Full Text] [PDF] Supplementary Data  

Immunology:

Development of Cellular Immune Responses against PAX5, a Novel Target for Cancer Immunotherapy

Mengyong Yan, Nourredine Himoudi, Martin Pule, Neil Sebire, Edmund Poon, Allison Blair, Owen Williams, and John Anderson
Cancer Res 2008 68: 8058-8065. doi: 10.1158/0008-5472.CAN-08-0153 [Abstract] [Full Text] [PDF] Supplementary Data  

Cancer Immunotherapy Targeting the High Molecular Weight Melanoma-Associated Antigen Protein Results in a Broad Antitumor Response and Reduction of Pericytes in the Tumor Vasculature

Paulo Cesar Maciag, Matthew M. Seavey, Zhen-Kun Pan, Soldano Ferrone, and Yvonne Paterson
Cancer Res 2008 68: 8066-8075. doi: 10.1158/0008-5472.CAN-08-0287 [Abstract] [Full Text] [PDF] Supplementary Data  

CD8⁺ T-Cell Responses against Hemoglobin-β Prevent Solid Tumor Growth

Hideo Komita, Xi Zhao, Jennifer L. Taylor, Louis J. Sparvero, Andrew A. Amoscato, Sean Alber, Simon C. Watkins, Angela D. Pardee, Amy K. Wesa, and Walter J. Storkus
Cancer Res 2008 68: 8076-8084. doi: 10.1158/0008-5472.CAN-08-0387 [Abstract] [Full Text] [PDF] Supplementary Data  

Presentation of Telomerase Reverse Transcriptase, a Self-Tumor Antigen, is Down-regulated by Histone Deacetylase Inhibition

Ilenia Pellicciotta, Xochitl Cortez-Gonzalez, Roman Sasik, Yoram Reiter, Gary Hardiman, Pierre Langlade-Demoyen, and Maurizio Zanetti
Cancer Res 2008 68: 8085-8093. doi: 10.1158/0008-5472.CAN-08-1014 [Abstract] [Full Text] [PDF]  

Molecular Biology, Pathobiology, and Genetics:

Abnormal DNA Methylation of CD133 in Colorectal and Glioblastoma Tumors

Joo Mi Yi, Hsing-Chen Tsai, Sabine C. Glöckner, Steven Lin, Joyce E. Ohm, Hari Easwaran, C. David James, Joseph F. Costello, Gregory Riggins, Charles G. Eberhart, John Laterra, Angelo L. Vescovi, Nita Ahuja, James G. Herman, Kornel E. Schuebel, and Stephen B. Baylin
Cancer Res 2008 68: 8094-8103. doi: 10.1158/0008-5472.CAN-07-6208 [Abstract] [Full Text] [PDF] Supplementary Data  

The Melanoma-Associated Antigen A3 Mediates Fibronectin-Controlled Cancer Progression and Metastasis

Wei Liu, Sonia Cheng, Sylvia L. Asa, and Shereen Ezzat
Cancer Res 2008 68: 8104-8112. doi: 10.1158/0008-5472.CAN-08-2132 [Abstract] [Full Text] [PDF] Supplementary Data  

A Bicistronic CYCLIN D1-TROP2 mRNA Chimera Demonstrates a Novel Oncogenic Mechanism in Human Cancer

Emanuela Guerra, Marco Trerotola, Roberta Dell' Arciprete, Veronica Bonasera, Barbara Palombo, Tarek El-Sewedy, Tommaso Ciccimarra, Carlo Crescenzi, Franco Lorenzini, Cosmo Rossi, Giovanna Vacca, Rossano Lattanzio, Mauro Piantelli, and Saverio Alberti
Cancer Res 2008 68: 8113-8121. doi: 10.1158/0008-5472.CAN-07-6135 [Abstract] [Full Text] [PDF] Supplementary Data  

Chromosomal Instability in Unirradiated Hemaopoietic Cells Induced by Macrophages Exposed In vivo to Ionizing Radiation

Sally A. Lorimore, Jennifer A. Chrystal, Joanne I. Robinson, Philip J. Coates, and Eric G. Wright
Cancer Res 2008 68: 8122-8126. doi: 10.1158/0008-5472.CAN-08-0698 [Abstract] [Full Text] [PDF]  

PIK3CA Cooperates with Other Phosphatidylinositol 3'-Kinase Pathway Mutations to Effect Oncogenic Transformation

Katsutoshi Oda, Jennifer Okada, Luika Timmerman, Pablo Rodriguez-Viciana, David Stokoe, Keiko Shoji, Yuji Taketani, Hiroyuki Kuramoto, Zachary A. Knight, Kevan M. Shokat, and Frank McCormick
Cancer Res 2008 68: 8127-8136. doi: 10.1158/0008-5472.CAN-08-0755 [Abstract] [Full Text] [PDF] Supplementary Data  

Functional Analysis of a Cell Cycle–Associated, Tumor-Suppressive Gene, Protein Tyrosine Phosphatase Receptor Type G, in Nasopharyngeal Carcinoma

Arthur Kwok Leung Cheung, Hong Lok Lung, Siu Chun Hung, Evan Wai Lok Law, Yue Cheng, Wing Lung Yau, Dhinoth Kumar Bangarusamy, Lance D. Miller, Edison Tak-Bun Liu, Jian-Yong Shao, Chang-Wei Kou, Daniel Chua, Eugene R. Zabarovsky, Sai Wah Tsao, Eric J. Stanbridge, and Maria Li Lung
Cancer Res 2008 68: 8137-8145. doi: 10.1158/0008-5472.CAN-08-0904 [Abstract] [Full Text] [PDF]  

Pericentromeric Instability and Spontaneous Emergence of Human Neoacrocentric and Minute Chromosomes in the Alternative Pathway of Telomere Lengthening

Sarantis Gagos, Maria Chiourea, Agni Christodoulidou, Eftichia Apostolou, Christina Raftopoulou, Samuel Deustch, Charles-Edward Jefford, Irmgard Irminger-Finger, Jerry W. Shay, and Stylianos E. Antonarakis
Cancer Res 2008 68: 8146-8155. doi: 10.1158/0008-5472.CAN-08-0945 [Abstract] [Full Text] [PDF] Supplementary Data  

Maintenance of Constitutive IB Kinase Activity by Glycogen Synthase Kinase-3/β in Pancreatic Cancer

Willie Wilson, III and Albert S. Baldwin
Cancer Res 2008 68: 8156-8163. doi: 10.1158/0008-5472.CAN-08-1061 [Abstract] [Full Text] [PDF] Supplementary Data  

MicroRNA-21 Targets a Network of Key Tumor-Suppressive Pathways in Glioblastoma Cells

Thales Papagiannakopoulos, Alice Shapiro, and Kenneth S. Kosik
Cancer Res 2008 68: 8164-8172. doi: 10.1158/0008-5472.CAN-08-1305 [Abstract] [Full Text] [PDF] Supplementary Data  

Androgenic Control of Transforming Growth Factor-β Signaling in Prostate Epithelial Cells through Transcriptional Suppression of Transforming Growth Factor-β Receptor II

Kyung Song, Hui Wang, Tracy L. Krebs, Seong-Jin Kim, and David Danielpour
Cancer Res 2008 68: 8173-8182. doi: 10.1158/0008-5472.CAN-08-2290 [Abstract] [Full Text] [PDF] Supplementary Data  

Tumor Microenvironment:

Endothelial p70 S6 Kinase 1 in Regulating Tumor Angiogenesis

Ling-Zhi Liu, Jenny Z. Zheng, Xin-Ru Wang, and Bing-Hua Jiang
Cancer Res 2008 68: 8183-8188. doi: 10.1158/0008-5472.CAN-08-0819 [Abstract] [Full Text] [PDF]  

Corrections:

Correction: Bmx Signaling in Irradiated Vascular Endothelium

Cancer Res 2008 68: 8189. doi: 10.1158/0008-5472.CAN-68-19-COR1 [Full Text] [PDF]  

Correction: GSK-3β in Radiation Injury to Hippocampal Neurons

Cancer Res 2008 68: 8189. doi: 10.1158/0008-5472.CAN-68-19-COR2 [Full Text] [PDF]  

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