AACR Centennial Series:

A History of Cancer Chemotherapy

Vincent T. DeVita, Jr. and Edward Chu
Cancer Res 2008 68: 8643-8653. doi: 10.1158/0008-5472.CAN-07-6611 [Abstract] [Full Text] [PDF]  

Reviews:

Just Say No to ATOH: How HIC1 Methylation Might Predispose Medulloblastoma to Lineage Addiction

Kimberly J. Briggs, Charles G. Eberhart, and D. Neil Watkins
Cancer Res 2008 68: 8654-8656. doi: 10.1158/0008-5472.CAN-08-1904 [Abstract] [Full Text] [PDF]  

Conspirators in a Capital Crime: Co-deletion of p18^INK4c and p16^INK4a/p14^ARF/p15^INK4b in Glioblastoma Multiforme

David A. Solomon, Jung-Sik Kim, Walter Jean, and Todd Waldman
Cancer Res 2008 68: 8657-8660. doi: 10.1158/0008-5472.CAN-08-2084 [Abstract] [Full Text] [PDF]  

Priority Reports:

Targeting YB-1 in HER-2 Overexpressing Breast Cancer Cells Induces Apoptosis via the mTOR/STAT3 Pathway and Suppresses Tumor Growth in Mice

Cathy Lee, Jaspreet Dhillon, Michelle Y.C. Wang, Yuanyuan Gao, Kaiji Hu, Eugene Park, Arezoo Astanehe, Mien-Chie Hung, Peter Eirew, Connie J. Eaves, and Sandra E. Dunn
Cancer Res 2008 68: 8661-8666. doi: 10.1158/0008-5472.CAN-08-1082 [Abstract] [Full Text] [PDF] Supplementary Data  

Neuropilin-1 Upholds Dedifferentiation and Propagation Phenotypes of Renal Cell Carcinoma Cells by Activating Akt and Sonic Hedgehog Axes

Ying Cao, Ling Wang, Debashis Nandy, Ying Zhang, Ananda Basu, Derek Radisky, and Debabrata Mukhopadhyay
Cancer Res 2008 68: 8667-8672. doi: 10.1158/0008-5472.CAN-08-2614 [Abstract] [Full Text] [PDF] Supplementary Data  

Tandem Duplication Producing a Novel Oncogenic BRAF Fusion Gene Defines the Majority of Pilocytic Astrocytomas

David T.W. Jones, Sylvia Kocialkowski, Lu Liu, Danita M. Pearson, L. Magnus Bäcklund, Koichi Ichimura, and V. Peter Collins
Cancer Res 2008 68: 8673-8677. doi: 10.1158/0008-5472.CAN-08-2097 [Abstract] [Full Text] [PDF] Supplementary Data  

Cell, Tumor, and Stem Cell Biology:

Bryostatin-5 Blocks Stromal Cell–Derived Factor-1 Induced Chemotaxis via Desensitization and Down-regulation of Cell Surface CXCR4 Receptors

Xing He, Liyan Fang, Jue Wang, Yanghua Yi, Shuyu Zhang, and Xin Xie
Cancer Res 2008 68: 8678-8686. doi: 10.1158/0008-5472.CAN-08-0294 [Abstract] [Full Text] [PDF] Supplementary Data  

Endogenous Interleukin-4 Promotes Tumor Development by Increasing Tumor Cell Resistance to Apoptosis

Zhiguang Li, Jing Jiang, Zibing Wang, Jinhua Zhang, Mingjie Xiao, Chunhui Wang, Yu Lu, and Zhihai Qin
Cancer Res 2008 68: 8687-8694. doi: 10.1158/0008-5472.CAN-08-0449 [Abstract] [Full Text] [PDF] Supplementary Data  

Different Roles of Estrogen Receptors and β in the Regulation of E-Cadherin Protein Levels in a Mouse Mammary Epithelial Cell Line

Luisa A. Helguero, Karolina Lindberg, Cissi Gardmo, Thomas Schwend, Jan-Åke Gustafsson, and Lars-Arne Haldosén
Cancer Res 2008 68: 8695-8704. doi: 10.1158/0008-5472.CAN-08-0788 [Abstract] [Full Text] [PDF] Supplementary Data  

p37^Ing1b Regulates B-Cell Proliferation and Cooperates with p53 to Suppress Diffuse Large B-Cell Lymphomagenesis

Andrew H. Coles, Concetta G.A. Marfella, Anthony N. Imbalzano, Heather A. Steinman, David S. Garlick, Rachel M. Gerstein, and Stephen N. Jones
Cancer Res 2008 68: 8705-8714. doi: 10.1158/0008-5472.CAN-08-0923 [Abstract] [Full Text] [PDF]  

Delocalization of the Microtubule Motor Dynein from Mitotic Spindles by the Human Papillomavirus E7 Oncoprotein Is Not Sufficient for Induction of Multipolar Mitoses

Christine L. Nguyen, Margaret E. McLaughlin-Drubin, and Karl Münger
Cancer Res 2008 68: 8715-8722. doi: 10.1158/0008-5472.CAN-08-1303 [Abstract] [Full Text] [PDF]  

Tnk1/Kos1 Knockout Mice Develop Spontaneous Tumors

Sarasija Hoare, Kishalay Hoare, Mary K. Reinhard, Young J. Lee, S. Paul Oh, and W. Stratford May, Jr.
Cancer Res 2008 68: 8723-8732. doi: 10.1158/0008-5472.CAN-08-1467 [Abstract] [Full Text] [PDF] Supplementary Data  

FoxM1B Transcriptionally Regulates Vascular Endothelial Growth Factor Expression and Promotes the Angiogenesis and Growth of Glioma Cells

Yujian Zhang, Nu Zhang, Bingbing Dai, Mingguang Liu, Raymond Sawaya, Keping Xie, and Suyun Huang
Cancer Res 2008 68: 8733-8742. doi: 10.1158/0008-5472.CAN-08-1968 [Abstract] [Full Text] [PDF] Supplementary Data  

Deleted in Liver Cancer 1 Controls Cell Migration through a Dia1-Dependent Signaling Pathway

Gerlinde Holeiter, Johanna Heering, Patrik Erlmann, Simone Schmid, Ruth Jähne, and Monilola A. Olayioye
Cancer Res 2008 68: 8743-8751. doi: 10.1158/0008-5472.CAN-08-0984 [Abstract] [Full Text] [PDF] Supplementary Data  

Reduced Eukaryotic Initiation Factor 2B-Subunit Expression Suppresses the Transformed Phenotype of Cells Overexpressing the Protein

James W. Gallagher, Neil Kubica, Scot R. Kimball, and Leonard S. Jefferson
Cancer Res 2008 68: 8752-8760. doi: 10.1158/0008-5472.CAN-08-1042 [Abstract] [Full Text] [PDF] Supplementary Data  

c-Cbl Interacts with CD38 and Promotes Retinoic Acid–Induced Differentiation and G₀ Arrest of Human Myeloblastic Leukemia Cells

Miaoqing Shen and Andrew Yen
Cancer Res 2008 68: 8761-8769. doi: 10.1158/0008-5472.CAN-08-1058 [Abstract] [Full Text] [PDF]  

Loss of NKX3.1 Favors Vascular Endothelial Growth Factor-C Expression in Prostate Cancer

Heyu Zhang, Michael H. Muders, Jinping Li, Francesca Rinaldo, Donald J. Tindall, and Kaustubh Datta
Cancer Res 2008 68: 8770-8778. doi: 10.1158/0008-5472.CAN-08-1912 [Abstract] [Full Text] [PDF]  

A Key Tyrosine (Y1494) in the β4 Integrin Regulates Multiple Signaling Pathways Important for Tumor Development and Progression

Udayan Dutta and Leslie M. Shaw
Cancer Res 2008 68: 8779-8787. doi: 10.1158/0008-5472.CAN-08-2125 [Abstract] [Full Text] [PDF] Supplementary Data  

Insulin-like Growth Factor 2 Is Required for Progression to Advanced Medulloblastoma in patched1 Heterozygous Mice

Ryan B. Corcoran, Tal Bachar Raveh, Monique T. Barakat, Eunice Y. Lee, and Matthew P. Scott
Cancer Res 2008 68: 8788-8795. doi: 10.1158/0008-5472.CAN-08-2135 [Abstract] [Full Text] [PDF]  

A Novel Association between p130^Cas and Resistance to the Chemotherapeutic Drug Adriamycin in Human Breast Cancer Cells

Huy Q. Ta, Keena S. Thomas, Randy S. Schrecengost, and Amy H. Bouton
Cancer Res 2008 68: 8796-8804. doi: 10.1158/0008-5472.CAN-08-2426 [Abstract] [Full Text] [PDF] Supplementary Data  

Endocrinology:

Estrogen-Related Receptor Is Critical for the Growth of Estrogen Receptor–Negative Breast Cancer

Rebecca A. Stein, Ching-yi Chang, Dmitri A. Kazmin, James Way, Thies Schroeder, Melanie Wergin, Mark W. Dewhirst, and Donald P. McDonnell
Cancer Res 2008 68: 8805-8812. doi: 10.1158/0008-5472.CAN-08-1594 [Abstract] [Full Text] [PDF] Supplementary Data  

Epidemiology:

Prevalence, Acquisition, and Clearance of Cervical Human Papillomavirus Infection among Women with Normal Cytology: Hawaii Human Papillomavirus Cohort Study

Marc T. Goodman, Yurii B. Shvetsov, Katharine McDuffie, Lynne R. Wilkens, Xuemei Zhu, Pamela J. Thompson, Lily Ning, Jeffrey Killeen, Lori Kamemoto, and Brenda Y. Hernandez
Cancer Res 2008 68: 8813-8824. doi: 10.1158/0008-5472.CAN-08-1380 [Abstract] [Full Text] [PDF] Supplementary Data  

Routine Diagnostic X-ray Examinations and Increased Frequency of Chromosome Translocations among U.S. Radiologic Technologists

Alice J. Sigurdson, Parveen Bhatti, Dale L. Preston, Michele Morin Doody, Diane Kampa, Bruce H. Alexander, Dayton Petibone, Lee C. Yong, Alan A. Edwards, Elaine Ron, and James D. Tucker
Cancer Res 2008 68: 8825-8831. doi: 10.1158/0008-5472.CAN-08-1691 [Abstract] [Full Text] [PDF]  

Gestational Hypertension, Preeclampsia, and Risk of Testicular Cancer

Andreas Pettersson, Lorenzo Richiardi, Sven Cnattingius, Magnus Kaijser, and Olof Akre
Cancer Res 2008 68: 8832-8836. doi: 10.1158/0008-5472.CAN-08-2309 [Abstract] [Full Text] [PDF]  

Association Study of Prostate Cancer Susceptibility Variants with Risks of Invasive Ovarian, Breast, and Colorectal Cancer

Honglin Song, Thibaud Koessler, Shahana Ahmed, Susan J. Ramus, Susanne Krüger Kjaer, Richard A. DiCioccio, Eva Wozniak, Estrid Hogdall, Alice S. Whittemore, Valerie McGuire, Bruce A.J. Ponder, Clare Turnbull, Sarah Hines, Nazneen Rahman, The Breast Cancer Susceptibility Collaboration (UK), Rosalind A. Eeles, Douglas F. Easton, Simon A. Gayther, Alison M. Dunning, and Paul D.P. Pharoah
Cancer Res 2008 68: 8837-8842. doi: 10.1158/0008-5472.CAN-08-2363 [Abstract] [Full Text] [PDF] Supplementary Data  

Experimental Therapeutics, Molecular Targets, and Chemical Biology:

Tumor Regression in Mice by Delivery of Bcl-2 Small Interfering RNA with Pegylated Cationic Liposomes

Satoru Sonoke, Toshihiro Ueda, Kae Fujiwara, Yohei Sato, Kazuchika Takagaki, Kazuko Hirabayashi, Tadaaki Ohgi, and Junichi Yano
Cancer Res 2008 68: 8843-8851. doi: 10.1158/0008-5472.CAN-08-0127 [Abstract] [Full Text] [PDF] Supplementary Data  

Identification of Pbx1, a Potential Oncogene, as a Notch3 Target Gene in Ovarian Cancer

Joon T. Park, Ie-Ming Shih, and Tian-Li Wang
Cancer Res 2008 68: 8852-8860. doi: 10.1158/0008-5472.CAN-08-0517 [Abstract] [Full Text] [PDF] Supplementary Data  

Modification of Cysteine Residue in p65 Subunit of Nuclear Factor-B (NF-B) by Picroliv Suppresses NF-B–Regulated Gene Products and Potentiates Apoptosis

Preetha Anand, Ajaikumar B. Kunnumakkara, Kuzhuvelil B. Harikumar, Kwang Seok Ahn, Vladimir Badmaev, and Bharat B. Aggarwal
Cancer Res 2008 68: 8861-8870. doi: 10.1158/0008-5472.CAN-08-1902 [Abstract] [Full Text] [PDF]  

Modulation of Orphan Nuclear Receptor Nur77-Mediated Apoptotic Pathway by Acetylshikonin and Analogues

Jie Liu, Wen Zhou, Shao-Shun Li, Zhe Sun, Bingzhen Lin, Yuan-Yuan Lang, Jia-You He, Xihua Cao, Tingdong Yan, Li Wang, Jiongming Lu, Young-Hoon Han, Yu Cao, Xiao-kun Zhang, and Jin-Zhang Zeng
Cancer Res 2008 68: 8871-8880. doi: 10.1158/0008-5472.CAN-08-1972 [Abstract] [Full Text] [PDF]  

The Taccalonolides: Microtubule Stabilizers That Circumvent Clinically Relevant Taxane Resistance Mechanisms

April L. Risinger, Evelyn M. Jackson, Lisa A. Polin, Gregory L. Helms, Desiree A. LeBoeuf, Patrick A. Joe, Elizabeth Hopper-Borge, Richard F. Ludueña, Gary D. Kruh, and Susan L. Mooberry
Cancer Res 2008 68: 8881-8888. doi: 10.1158/0008-5472.CAN-08-2037 [Abstract] [Full Text] [PDF] Supplementary Data  

Milk Fat Globule EGF-8 Promotes Melanoma Progression through Coordinated Akt and Twist Signaling in the Tumor Microenvironment

Masahisa Jinushi, Yukoh Nakazaki, Daniel R. Carrasco, Dobrin Draganov, Nicholas Souders, Matthew Johnson, Martin C. Mihm, and Glenn Dranoff
Cancer Res 2008 68: 8889-8898. doi: 10.1158/0008-5472.CAN-08-2147 [Abstract] [Full Text] [PDF] Supplementary Data  

The Anaplastic Lymphoma Kinase Controls Cell Shape and Growth of Anaplastic Large Cell Lymphoma through Cdc42 Activation

Chiara Ambrogio, Claudia Voena, Andrea D. Manazza, Cinzia Martinengo, Carlotta Costa, Tomas Kirchhausen, Emilio Hirsch, Giorgio Inghirami, and Roberto Chiarle
Cancer Res 2008 68: 8899-8907. doi: 10.1158/0008-5472.CAN-08-2568 [Abstract] [Full Text] [PDF] Supplementary Data  

ERR Mediates Tamoxifen Resistance in Novel Models of Invasive Lobular Breast Cancer

Rebecca B. Riggins, Jennifer P-J. Lan, Uwe Klimach, Alan Zwart, Luciane R. Cavalli, Bassem R. Haddad, Li Chen, Ting Gong, Jianhua Xuan, Stephen P. Ethier, and Robert Clarke
Cancer Res 2008 68: 8908-8917. doi: 10.1158/0008-5472.CAN-08-2669 [Abstract] [Full Text] [PDF] Supplementary Data  

Baicalein Overcomes Tumor Necrosis Factor–Related Apoptosis-Inducing Ligand Resistance via Two Different Cell-Specific Pathways in Cancer Cells but not in Normal Cells

Hiroya Taniguchi, Tatsushi Yoshida, Mano Horinaka, Takashi Yasuda, Ahmed E. Goda, Masako Konishi, Miki Wakada, Keisho Kataoka, Toshikazu Yoshikawa, and Toshiyuki Sakai
Cancer Res 2008 68: 8918-8927. doi: 10.1158/0008-5472.CAN-08-1120 [Abstract] [Full Text] [PDF] Supplementary Data  

Bioselection of a Gain of Function Mutation that Enhances Adenovirus 5 Release and Improves Its Antitumoral Potency

Alena Gros, Jordi Martínez-Quintanilla, Cristina Puig, Sonia Guedan, David G. Molleví, Ramon Alemany, and Manel Cascallo
Cancer Res 2008 68: 8928-8937. doi: 10.1158/0008-5472.CAN-08-1145 [Abstract] [Full Text] [PDF] Supplementary Data  

Zerumbone Down-regulates Chemokine Receptor CXCR4 Expression Leading to Inhibition of CXCL12-Induced Invasion of Breast and Pancreatic Tumor Cells

Bokyung Sung, Sonia Jhurani, Kwang Seok Ahn, Yoichi Mastuo, Tingfang Yi, Sushovan Guha, Mingyao Liu, and Bharat B. Aggarwal
Cancer Res 2008 68: 8938-8944. doi: 10.1158/0008-5472.CAN-08-2155 [Abstract] [Full Text] [PDF]  

Lowering Bone Mineral Affinity of Bisphosphonates as a Therapeutic Strategy to Optimize Skeletal Tumor Growth Inhibition In vivo

Pierrick G.J. Fournier, Florence Daubiné, Mark W. Lundy, Michael J. Rogers, Frank H. Ebetino, and Philippe Clézardin
Cancer Res 2008 68: 8945-8953. doi: 10.1158/0008-5472.CAN-08-2195 [Abstract] [Full Text] [PDF] Supplementary Data  

Molecular Biology, Pathobiology, and Genetics:

DNA Hypomethylation Arises Later in Prostate Cancer Progression than CpG Island Hypermethylation and Contributes to Metastatic Tumor Heterogeneity

Srinivasan Yegnasubramanian, Michael C. Haffner, Yonggang Zhang, Bora Gurel, Toby C. Cornish, Zhijin Wu, Rafael A. Irizarry, James Morgan, Jessica Hicks, Theodore L. DeWeese, William B. Isaacs, G. Steven Bova, Angelo M. De Marzo, and William G. Nelson
Cancer Res 2008 68: 8954-8967. doi: 10.1158/0008-5472.CAN-07-6088 [Abstract] [Full Text] [PDF] Supplementary Data  

EWS-FLI1 Induces Developmental Abnormalities and Accelerates Sarcoma Formation in a Transgenic Mouse Model

Patrick P. Lin, Manoj K. Pandey, Fenghua Jin, Shunbin Xiong, Michael Deavers, John M. Parant, and Guillermina Lozano
Cancer Res 2008 68: 8968-8975. doi: 10.1158/0008-5472.CAN-08-0573 [Abstract] [Full Text] [PDF]  

Roles for MicroRNAs, miR-93 and miR-130b, and Tumor Protein 53–Induced Nuclear Protein 1 Tumor Suppressor in Cell Growth Dysregulation by Human T-Cell Lymphotrophic Virus 1

Man Lung Yeung, Jun-ichirou Yasunaga, Yamina Bennasser, Nelson Dusetti, David Harris, Nafees Ahmad, Masao Matsuoka, and Kuan-Teh Jeang
Cancer Res 2008 68: 8976-8985. doi: 10.1158/0008-5472.CAN-08-0769 [Abstract] [Full Text] [PDF] Supplementary Data  

Enhanced Sensitivity of the RET Proto-Oncogene to Ionizing Radiation In vitro

Claudia Béu Volpato, Minerva Martínez-Alfaro, Raffaella Corvi, Coralie Gabus, Sylvie Sauvaigo, Pietro Ferrari, Elena Bonora, Alessandro De Grandi, and Giovanni Romeo
Cancer Res 2008 68: 8986-8992. doi: 10.1158/0008-5472.CAN-08-1032 [Abstract] [Full Text] [PDF]  

Common Familial Colorectal Cancer Linked to Chromosome 7q31: A Genome-Wide Analysis

Deborah W. Neklason, Richard A. Kerber, David B. Nilson, Hoda Anton-Culver, Ann G. Schwartz, Constance A. Griffin, Jan T. Lowery, Joellen M. Schildkraut, James P. Evans, Gail E. Tomlinson, Louise C. Strong, Alexander R. Miller, Jill E. Stopfer, Dianne M. Finkelstein, Prakash M. Nadkarni, Carol H. Kasten, Geraldine P. Mineau, and Randall W. Burt
Cancer Res 2008 68: 8993-8997. doi: 10.1158/0008-5472.CAN-08-1376 [Abstract] [Full Text] [PDF] Supplementary Data  

Aurora Kinase A Inhibition Leads to p73-Dependent Apoptosis in p53-Deficient Cancer Cells

Altaf A. Dar, Abbes Belkhiri, Jeffrey Ecsedy, Alexander Zaika, and Wael El-Rifai
Cancer Res 2008 68: 8998-9004. doi: 10.1158/0008-5472.CAN-08-2658 [Abstract] [Full Text] [PDF]  

Carcinogen-Induced Gene Promoter Hypermethylation Is Mediated by DNMT1 and Causal for Transformation of Immortalized Bronchial Epithelial Cells

Leah A. Damiani, Christin M. Yingling, Shuguang Leng, Paul E. Romo, Jun Nakamura, and Steven A. Belinsky
Cancer Res 2008 68: 9005-9014. doi: 10.1158/0008-5472.CAN-08-1276 [Abstract] [Full Text] [PDF] Supplementary Data  

Imatinib Mesylate Induces Quiescence in Gastrointestinal Stromal Tumor Cells through the CDH1-SKP2-p27^Kip1 Signaling Axis

Ying Liu, Sophie A. Perdreau, Payel Chatterjee, Linan Wang, Shih-Fan Kuan, and Anette Duensing
Cancer Res 2008 68: 9015-9023. doi: 10.1158/0008-5472.CAN-08-1935 [Abstract] [Full Text] [PDF] Supplementary Data  

Prevention:

Plumbagin, a Medicinal Plant–Derived Naphthoquinone, Is a Novel Inhibitor of the Growth and Invasion of Hormone-Refractory Prostate Cancer

Moammir H. Aziz, Nancy E. Dreckschmidt, and Ajit K. Verma
Cancer Res 2008 68: 9024-9032. doi: 10.1158/0008-5472.CAN-08-2494 [Abstract] [Full Text] [PDF]  

Systems Biology and Emerging Technologies:

Efficacy of Weekly Docetaxel and Bevacizumab in Mesenchymal Chondrosarcoma: A New Theranostic Method Combining Xenografted Biopsies with a Mathematical Model

Boris Gorelik, Irit Ziv, Revital Shohat, Michael Wick, W. David Hankins, David Sidransky, and Zvia Agur
Cancer Res 2008 68: 9033-9040. doi: 10.1158/0008-5472.CAN-08-1723 [Abstract] [Full Text] [PDF] Supplementary Data  

CCCTC-Binding Factor Confines the Distal Action of Estrogen Receptor

Chang S. Chan and Jun S. Song
Cancer Res 2008 68: 9041-9049. doi: 10.1158/0008-5472.CAN-08-2632 [Abstract] [Full Text] [PDF] Supplementary Data  

Tumor Microenvironment:

Macrophage-Derived SPARC Bridges Tumor Cell-Extracellular Matrix Interactions toward Metastasis

Sabina Sangaletti, Emma Di Carlo, Silvia Gariboldi, Silvia Miotti, Barbara Cappetti, Mariella Parenza, Cristiano Rumio, Rolf A. Brekken, Claudia Chiodoni, and Mario P. Colombo
Cancer Res 2008 68: 9050-9059. doi: 10.1158/0008-5472.CAN-08-1327 [Abstract] [Full Text] [PDF] Supplementary Data  

The Chemokine Receptor CX3CR1 Is Involved in the Neural Tropism and Malignant Behavior of Pancreatic Ductal Adenocarcinoma

Federica Marchesi, Lorenzo Piemonti, Giuseppe Fedele, Annarita Destro, Massimo Roncalli, Luca Albarello, Claudio Doglioni, Achille Anselmo, Andrea Doni, Paolo Bianchi, Luigi Laghi, Alberto Malesci, Luigi Cervo, MariaLuisa Malosio, Michele Reni, Alessandro Zerbi, Valerio Di Carlo, Alberto Mantovani, and Paola Allavena
Cancer Res 2008 68: 9060-9069. doi: 10.1158/0008-5472.CAN-08-1810 [Abstract] [Full Text] [PDF] Supplementary Data  

Moderate Expression of Prostate-Specific Membrane Antigen, a Tissue Differentiation Antigen and Folate Hydrolase, Facilitates Prostate Carcinogenesis

Veronica Yao, Anil Parwani, Christoph Maier, Warren DeWayne Heston, and Dean John Bacich
Cancer Res 2008 68: 9070-9077. doi: 10.1158/0008-5472.CAN-08-2328 [Abstract] [Full Text] [PDF]  

Targeting Melanoma Growth and Metastasis with Systemic Delivery of Liposome-Incorporated Protease-Activated Receptor-1 Small Interfering RNA

Gabriel J. Villares, Maya Zigler, Hua Wang, Vladislava O. Melnikova, Hong Wu, Ran Friedman, Michael C. Leslie, Pablo E. Vivas-Mejia, Gabriel Lopez-Berestein, Anil K. Sood, and Menashe Bar-Eli
Cancer Res 2008 68: 9078-9086. doi: 10.1158/0008-5472.CAN-08-2397 [Abstract] [Full Text] [PDF]  

Fibroblasts Isolated from Common Sites of Breast Cancer Metastasis Enhance Cancer Cell Growth Rates and Invasiveness in an Interleukin-6–Dependent Manner

Adam W. Studebaker, Gianluca Storci, Jillian L. Werbeck, Pasquale Sansone, A. Kate Sasser, Simona Tavolari, Tim Huang, Michael W.Y. Chan, Frank C. Marini, Thomas J. Rosol, Massimiliano Bonafé, and Brett M. Hall
Cancer Res 2008 68: 9087-9095. doi: 10.1158/0008-5472.CAN-08-0400 [Abstract] [Full Text] [PDF] Supplementary Data  

Activation of Matrix Metalloproteinase-2 (MMP-2) by Membrane Type 1 Matrix Metalloproteinase through an Artificial Receptor for ProMMP-2 Generates Active MMP-2

Yuki Nishida, Hisashi Miyamori, Erik W. Thompson, Takahisa Takino, Yoshio Endo, and Hiroshi Sato
Cancer Res 2008 68: 9096-9104. doi: 10.1158/0008-5472.CAN-08-2522 [Abstract] [Full Text] [PDF]  

Corrections:

Correction: Granulocyte Maturation after Butyrate Treatment of Leukemic Blasts

Cancer Res 2008 68: 9105. doi: 10.1158/0008-5472.CAN-68-21-COR1 [Full Text] [PDF]  

Correction: ABCC3 Amplification and Taxane Resistance

Cancer Res 2008 68: 9105. doi: 10.1158/0008-5472.CAN-68-21-COR2 [Full Text] [PDF]  

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