Reviews:

Transforming Growth Factor β: Tumor Suppressor or Promoter? Are Host Immune Cells the Answer?

Li Yang and Harold L. Moses
Cancer Res 2008 68: 9107-9111. doi: 10.1158/0008-5472.CAN-08-2556 [Abstract] [Full Text] [PDF]  

Does the Renin-Angiotensin System Participate in Regulation of Human Vasculogenesis and Angiogenesis?

Aarif Y. Khakoo, Richard L. Sidman, Renata Pasqualini, and Wadih Arap
Cancer Res 2008 68: 9112-9115. doi: 10.1158/0008-5472.CAN-08-0851 [Abstract] [Full Text] [PDF]  

Perspectives in Cancer Research:

The Role of Parental and Grandparental Epigenetic Alterations in Familial Cancer Risk

Jessica L. Fleming, Tim H-M. Huang, and Amanda Ewart Toland
Cancer Res 2008 68: 9116-9121. doi: 10.1158/0008-5472.CAN-08-2184 [Abstract] [Full Text] [PDF]  

Ph.D. Training in Cancer Biology

Frank M. Torti, Dario Altieri, James Broach, Hung Fan, Michael Lotze, James Manfredi, Lynn Matrisian, Dihua Yu, Amato Giaccia The Cancer Biology Training Consortium
Cancer Res 2008 68: 9122-9124. doi: 10.1158/0008-5472.CAN-08-2626 [Full Text] [PDF]  

Priority Reports:

Targeting of the Bmi-1 Oncogene/Stem Cell Renewal Factor by MicroRNA-128 Inhibits Glioma Proliferation and Self-Renewal

Jakub Godlewski, Michal O. Nowicki, Agnieszka Bronisz, Shanté Williams, Akihiro Otsuki, Gerard Nuovo, Abhik RayChaudhury, Herbert B. Newton, E. Antonio Chiocca, and Sean Lawler
Cancer Res 2008 68: 9125-9130. doi: 10.1158/0008-5472.CAN-08-2629 [Abstract] [Full Text] [PDF]  

Induction of Cytoplasmic Accumulation of p53: A Mechanism for Low Levels of Arsenic Exposure to Predispose Cells for Malignant Transformation

Yelin Huang, Jianglin Zhang, Kevin T. McHenry, Mihee M. Kim, Weiqi Zeng, Vanessa Lopez-Pajares, Christian C. Dibble, Joseph P. Mizgerd, and Zhi-Min Yuan
Cancer Res 2008 68: 9131-9136. doi: 10.1158/0008-5472.CAN-08-3025 [Abstract] [Full Text] [PDF]  

Smokers with the CHRNA Lung Cancer–Associated Variants Are Exposed to Higher Levels of Nicotine Equivalents and a Carcinogenic Tobacco-Specific Nitrosamine

Loïc Le Marchand, Kiersten S. Derby, Sharon E. Murphy, Stephen S. Hecht, Dorothy Hatsukami, Steven G. Carmella, Maarit Tiirikainen, and Hansong Wang
Cancer Res 2008 68: 9137-9140. doi: 10.1158/0008-5472.CAN-08-2271 [Abstract] [Full Text] [PDF]  

Erlotinib Attenuates Homologous Recombinational Repair of Chromosomal Breaks in Human Breast Cancer Cells

Liping Li, Hong Wang, Eddy S. Yang, Carlos L. Arteaga, and Fen Xia
Cancer Res 2008 68: 9141-9146. doi: 10.1158/0008-5472.CAN-08-1127 [Abstract] [Full Text] [PDF] Supplementary Data  

Cell, Tumor, and Stem Cell Biology:

Lysosomal Cathepsin B Participates in the Podosome-Mediated Extracellular Matrix Degradation and Invasion via Secreted Lysosomes in v-Src Fibroblasts

Chun Tu, Cesar F. Ortega-Cava, Gengsheng Chen, Norvin D. Fernandes, Dora Cavallo-Medved, Bonnie F. Sloane, Vimla Band, and Hamid Band
Cancer Res 2008 68: 9147-9156. doi: 10.1158/0008-5472.CAN-07-5127 [Abstract] [Full Text] [PDF] Supplementary Data  

Bone Morphogenetic Protein-7 Inhibits Telomerase Activity, Telomere Maintenance, and Cervical Tumor Growth

Lucy Cassar, He Li, Alexander Ruvantha Pinto, Craig Nicholls, Sharyn Bayne, and Jun-Ping Liu
Cancer Res 2008 68: 9157-9166. doi: 10.1158/0008-5472.CAN-08-1323 [Abstract] [Full Text] [PDF]  

Association of Autophagy Defect with a Malignant Phenotype and Poor Prognosis of Hepatocellular Carcinoma

Zhen-Bin Ding, Ying-Hong Shi, Jian Zhou, Shuang-Jian Qiu, Yang Xu, Zhi Dai, Guo-Ming Shi, Xiao-Ying Wang, Ai-Wu Ke, Bin Wu, and Jia Fan
Cancer Res 2008 68: 9167-9175. doi: 10.1158/0008-5472.CAN-08-1573 [Abstract] [Full Text] [PDF] Supplementary Data  

"Active" Cancer Immunotherapy by Anti-Met Antibody Gene Transfer

Elisa Vigna, Giovanni Pacchiana, Massimiliano Mazzone, Cristina Chiriaco, Lara Fontani, Cristina Basilico, Selma Pennacchietti, and Paolo M. Comoglio
Cancer Res 2008 68: 9176-9183. doi: 10.1158/0008-5472.CAN-08-1688 [Abstract] [Full Text] [PDF] Supplementary Data  

Serotonin Metabolism Is Dysregulated in Cholangiocarcinoma, which Has Implications for Tumor Growth

Gianfranco Alpini, Pietro Invernizzi, Eugenio Gaudio, Julie Venter, Shelley Kopriva, Francesca Bernuzzi, Paolo Onori, Antonio Franchitto, Monique Coufal, Gabriel Frampton, Domenico Alvaro, Sum P. Lee, Marco Marzioni, Antonio Benedetti, and Sharon DeMorrow
Cancer Res 2008 68: 9184-9193. doi: 10.1158/0008-5472.CAN-08-2133 [Abstract] [Full Text] [PDF] Supplementary Data  

Role of a Novel Splice Variant of Mitotic Arrest Deficient 1 (MAD1), MAD1β, in Mitotic Checkpoint Control in Liver Cancer

Karen Man-Fong Sze, Yick-Pang Ching, Dong-Yan Jin, and Irene Oi-Lin Ng
Cancer Res 2008 68: 9194-9201. doi: 10.1158/0008-5472.CAN-08-2600 [Abstract] [Full Text] [PDF]  

NOTCH Is Part of the Transcriptional Network Regulating Cell Growth and Survival in Mouse Plasmacytomas

Dong-Mi Shin, Daniel J. Shaffer, Hongsheng Wang, Derry C. Roopenian, and Herbert C. Morse, III
Cancer Res 2008 68: 9202-9211. doi: 10.1158/0008-5472.CAN-07-6555 [Abstract] [Full Text] [PDF] Supplementary Data  

Hypoxia-Inducible Factor-2 Correlates to Distant Recurrence and Poor Outcome in Invasive Breast Cancer

Karolina Helczynska, Anna-Maria Larsson, Linda Holmquist Mengelbier, Esther Bridges, Erik Fredlund, Signe Borgquist, Göran Landberg, Sven Påhlman, and Karin Jirström
Cancer Res 2008 68: 9212-9220. doi: 10.1158/0008-5472.CAN-08-1135 [Abstract] [Full Text] [PDF] Supplementary Data  

Phosphatidylinositol 3-Kinase Hyperactivation Results in Lapatinib Resistance that Is Reversed by the mTOR/Phosphatidylinositol 3-Kinase Inhibitor NVP-BEZ235

Pieter J.A. Eichhorn, Magüi Gili, Maurizio Scaltriti, Violeta Serra, Marta Guzman, Wouter Nijkamp, Roderick L. Beijersbergen, Vanesa Valero, Joan Seoane, René Bernards, and José Baselga
Cancer Res 2008 68: 9221-9230. doi: 10.1158/0008-5472.CAN-08-1740 [Abstract] [Full Text] [PDF] Supplementary Data  

MUC4, a Multifunctional Transmembrane Glycoprotein, Induces Oncogenic Transformation of NIH3T3 Mouse Fibroblast Cells

Sangeeta Bafna, Ajay P. Singh, Nicolas Moniaux, James D. Eudy, Jane L. Meza, and Surinder K. Batra
Cancer Res 2008 68: 9231-9238. doi: 10.1158/0008-5472.CAN-08-3135 [Abstract] [Full Text] [PDF] Supplementary Data  

Endocrinology:

Angiotensin II Induces DNA Damage in the Kidney

Ursula Schmid, Helga Stopper, Frank Schweda, Nina Queisser, and Nicole Schupp
Cancer Res 2008 68: 9239-9246. doi: 10.1158/0008-5472.CAN-08-1310 [Abstract] [Full Text] [PDF]  

Evidence for an Important Role of CIDEA in Human Cancer Cachexia

Jurga Laurencikiene, Britta M. Stenson, Elisabet Arvidsson Nordström, Thorhallur Agustsson, Dominique Langin, Bengt Isaksson, Johan Permert, Mikael Rydén, and Peter Arner
Cancer Res 2008 68: 9247-9254. doi: 10.1158/0008-5472.CAN-08-1343 [Abstract] [Full Text] [PDF]  

The Mitogen-Activated Protein Kinase Phosphatase Vaccinia H1–Related Protein Inhibits Apoptosis in Prostate Cancer Cells and Is Overexpressed in Prostate Cancer

Yke Jildouw Arnoldussen, Petra I. Lorenzo, Maria E. Pretorius, Håkon Wæhre, Bjørn Risberg, Gunhild M. Mælandsmo, Håvard E. Danielsen, and Fahri Saatcioglu
Cancer Res 2008 68: 9255-9264. doi: 10.1158/0008-5472.CAN-08-1224 [Abstract] [Full Text] [PDF] Supplementary Data  

Small Interfering RNA Molecules Targeting Endothelin-Converting Enzyme-1 Inhibit Endothelin-1 Synthesis and the Invasive Phenotype of Ovarian Carcinoma Cells

Oleg Rayhman, Eyal Klipper, Laurent Muller, Ben Davidson, Reuven Reich, and Rina Meidan
Cancer Res 2008 68: 9265-9273. doi: 10.1158/0008-5472.CAN-08-2093 [Abstract] [Full Text] [PDF] Supplementary Data  

Epidemiology:

A Prospective Study of Meat and Fat Intake in Relation to Small Intestinal Cancer

Amanda J. Cross, Michael F. Leitzmann, Amy F. Subar, Frances E. Thompson, Albert R. Hollenbeck, and Arthur Schatzkin
Cancer Res 2008 68: 9274-9279. doi: 10.1158/0008-5472.CAN-08-2015 [Abstract] [Full Text] [PDF]  

Experimental Therapeutics, Molecular Targets, and Chemical Biology:

Targeting HER2-Positive Breast Cancer with Trastuzumab-DM1, an Antibody–Cytotoxic Drug Conjugate

Gail D. Lewis Phillips, Guangmin Li, Debra L. Dugger, Lisa M. Crocker, Kathryn L. Parsons, Elaine Mai, Walter A. Blättler, John M. Lambert, Ravi V.J. Chari, Robert J. Lutz, Wai Lee T. Wong, Frederic S. Jacobson, Hartmut Koeppen, Ralph H. Schwall, Sara R. Kenkare-Mitra, Susan D. Spencer, and Mark X. Sliwkowski
Cancer Res 2008 68: 9280-9290. doi: 10.1158/0008-5472.CAN-08-1776 [Abstract] [Full Text] [PDF]  

Hypoxia-Mediated Induction of the Polyamine System Provides Opportunities for Tumor Growth Inhibition by Combined Targeting of Vascular Endothelial Growth Factor and Ornithine Decarboxylase

Katrin J. Svensson, Johanna E. Welch, Paulina Kucharzewska, Per Bengtson, Maria Bjurberg, Sven Påhlman, Gerdy B. Ten Dam, Lo Persson, and Mattias Belting
Cancer Res 2008 68: 9291-9301. doi: 10.1158/0008-5472.CAN-08-2340 [Abstract] [Full Text] [PDF]  

PEA-15 Induces Autophagy in Human Ovarian Cancer Cells and Is Associated with Prolonged Overall Survival

Chandra Bartholomeusz, Daniel Rosen, Caimiao Wei, Anna Kazansky, Fumiyuki Yamasaki, Takeshi Takahashi, Hiroaki Itamochi, Seiji Kondo, Jinsong Liu, and Naoto T. Ueno
Cancer Res 2008 68: 9302-9310. doi: 10.1158/0008-5472.CAN-08-2592 [Abstract] [Full Text] [PDF] Supplementary Data  

Human Adrenomedullin Up-regulates Interleukin-13 Receptor 2 Chain in Prostate Cancer In vitro and In vivo: A Novel Approach to Sensitize Prostate Cancer to Anticancer Therapy

Bharat H. Joshi, Pamela Leland, Alfonso Calvo, Jeffrey E. Green, and Raj K. Puri
Cancer Res 2008 68: 9311-9317. doi: 10.1158/0008-5472.CAN-08-2810 [Abstract] [Full Text] [PDF] Supplementary Data  

Antitumor Effect of SN-38–Releasing Polymeric Micelles, NK012, on Spontaneous Peritoneal Metastases from Orthotopic Gastric Cancer in Mice Compared with Irinotecan

Takako Eguchi Nakajima, Kazuyoshi Yanagihara, Misato Takigahira, Masahiro Yasunaga, Ken Kato, Tetsuya Hamaguchi, Yasuhide Yamada, Yasuhiro Shimada, Keichiro Mihara, Takahiro Ochiya, and Yasuhiro Matsumura
Cancer Res 2008 68: 9318-9322. doi: 10.1158/0008-5472.CAN-08-2822 [Abstract] [Full Text] [PDF]  

Preferential Cytotoxicity of Bortezomib toward Hypoxic Tumor Cells via Overactivation of Endoplasmic Reticulum Stress Pathways

Diane R. Fels, Jiangbin Ye, Andrew T. Segan, Steven J. Kridel, Michael Spiotto, Michael Olson, Albert C. Koong, and Constantinos Koumenis
Cancer Res 2008 68: 9323-9330. doi: 10.1158/0008-5472.CAN-08-2873 [Abstract] [Full Text] [PDF] Supplementary Data  

Repression of 15-Hydroxyprostaglandin Dehydrogenase Involves Histone Deacetylase 2 and Snail in Colorectal Cancer

Michael G. Backlund, Jason R. Mann, Vijaykumar R. Holla, Qiong Shi, Takikoku Daikoku, Sudhansu K. Dey, and Raymond N. DuBois
Cancer Res 2008 68: 9331-9337. doi: 10.1158/0008-5472.CAN-08-2893 [Abstract] [Full Text] [PDF] Supplementary Data  

Interplay between the Nuclear Receptor Pregnane X Receptor and the Uptake Transporter Organic Anion Transporter Polypeptide 1A2 Selectively Enhances Estrogen Effects in Breast Cancer

Henriette E. Meyer zu Schwabedissen, Rommel G. Tirona, Cindy S. Yip, Richard H. Ho, and Richard B. Kim
Cancer Res 2008 68: 9338-9347. doi: 10.1158/0008-5472.CAN-08-0265 [Abstract] [Full Text] [PDF]  

OSU-03012, a Novel Celecoxib Derivative, Induces Reactive Oxygen Species–Related Autophagy in Hepatocellular Carcinoma

Ming Gao, Pei Yen Yeh, Yen-Shen Lu, Chih-Hung Hsu, Kuen-Feng Chen, Wei-Chung Lee, Wen-Chi Feng, Ching-Shih Chen, Min-Liang Kuo, and Ann-Lii Cheng
Cancer Res 2008 68: 9348-9357. doi: 10.1158/0008-5472.CAN-08-1642 [Abstract] [Full Text] [PDF]  

p53-Inducible Ribonucleotide Reductase (p53R2/RRM2B) Is a DNA Hypomethylation–Independent Decitabine Gene Target That Correlates with Clinical Response in Myelodysplastic Syndrome/Acute Myelogenous Leukemia

Petra A. Link, Maria R. Baer, Smitha R. James, David A. Jones, and Adam R. Karpf
Cancer Res 2008 68: 9358-9366. doi: 10.1158/0008-5472.CAN-08-1860 [Abstract] [Full Text] [PDF] Supplementary Data  

A Human Antibody–Drug Conjugate Targeting EphA2 Inhibits Tumor Growth In vivo

Dowdy Jackson, John Gooya, Shenlan Mao, Krista Kinneer, Linda Xu, Margarita Camara, Christine Fazenbaker, Ryan Fleming, Sudha Swamynathan, Damon Meyer, Peter D. Senter, Changshou Gao, Herren Wu, Michael Kinch, Steven Coats, Peter A. Kiener, and David A. Tice
Cancer Res 2008 68: 9367-9374. doi: 10.1158/0008-5472.CAN-08-1933 [Abstract] [Full Text] [PDF]  

Genetic Predictors of MEK Dependence in Non–Small Cell Lung Cancer

Christine A. Pratilas, Aphrothiti J. Hanrahan, Ensar Halilovic, Yogindra Persaud, Junichi Soh, Dhananjay Chitale, Hisayuki Shigematsu, Hiromasa Yamamoto, Ayana Sawai, Manickam Janakiraman, Barry S. Taylor, William Pao, Shinichi Toyooka, Marc Ladanyi, Adi Gazdar, Neal Rosen, and David B. Solit
Cancer Res 2008 68: 9375-9383. doi: 10.1158/0008-5472.CAN-08-2223 [Abstract] [Full Text] [PDF] Supplementary Data  

SM-164: A Novel, Bivalent Smac Mimetic That Induces Apoptosis and Tumor Regression by Concurrent Removal of the Blockade of cIAP-1/2 and XIAP

Jianfeng Lu, Longchuan Bai, Haiying Sun, Zaneta Nikolovska-Coleska, Donna McEachern, Su Qiu, Rebecca S. Miller, Han Yi, Sanjeev Shangary, Yi Sun, Jennifer L. Meagher, Jeanne A. Stuckey, and Shaomeng Wang
Cancer Res 2008 68: 9384-9393. doi: 10.1158/0008-5472.CAN-08-2655 [Abstract] [Full Text] [PDF] Supplementary Data  

Synergistic Proapoptotic Activity of Recombinant TRAIL Plus the Akt Inhibitor Perifosine in Acute Myelogenous Leukemia Cells

Pier Luigi Tazzari, Giovanna Tabellini, Francesca Ricci, Veronica Papa, Roberta Bortul, Francesca Chiarini, Camilla Evangelisti, Giovanni Martinelli, Andrea Bontadini, Lucio Cocco, James A. McCubrey, and Alberto M. Martelli
Cancer Res 2008 68: 9394-9403. doi: 10.1158/0008-5472.CAN-08-2815 [Abstract] [Full Text] [PDF] Supplementary Data  

Immunology:

AKT1 Inhibits Homologous Recombination by Inducing Cytoplasmic Retention of BRCA1 and RAD51

Isabelle Plo, Corentin Laulier, Laurent Gauthier, Fabienne Lebrun, Fabien Calvo, and Bernard S. Lopez
Cancer Res 2008 68: 9404-9412. doi: 10.1158/0008-5472.CAN-08-0861 [Abstract] [Full Text] [PDF] Supplementary Data  

Involvement of the Leptin Receptor in the Immune Response in Intestinal Cancer

Nijez Aloulou, Sylvie Bastuji-Garin, Sabine Le Gouvello, Mohammad Abolhassani, Marie Thérèse Chaumette, Antoine Charachon, Karen Leroy, and Iradj Sobhani
Cancer Res 2008 68: 9413-9422. doi: 10.1158/0008-5472.CAN-08-0909 [Abstract] [Full Text] [PDF] Supplementary Data  

Leptin Receptor–Related Immune Response in Colorectal Tumors: The Role of Colonocytes and Interleukin-8

Mohammad Abolhassani, Nijez Aloulou, Marie Thérèse Chaumette, Thomas Aparicio, Nadine Martin-Garcia, Hicham Mansour, Sabine Le Gouvello, Jean Charles Delchier, and Iradj Sobhani
Cancer Res 2008 68: 9423-9432. doi: 10.1158/0008-5472.CAN-08-1017 [Abstract] [Full Text] [PDF] Supplementary Data  

Killer Dendritic Cells Link Innate and Adaptive Immunity against Established Osteosarcoma in Rats

Camille Chauvin, Jean-Marie Philippeau, Caroline Hémont, Francois-Xavier Hubert, Yohann Wittrant, Francois Lamoureux, Benjamin Trinité, Dominique Heymann, Françoise Rédini, and Régis Josien
Cancer Res 2008 68: 9433-9440. doi: 10.1158/0008-5472.CAN-08-0104 [Abstract] [Full Text] [PDF]  

Type 2 Bias of T Cells Expanded from the Blood of Melanoma Patients Switched to Type 1 by IL-12p70 mRNA–Transfected Dendritic Cells

Kira Minkis, Daniel G. Kavanagh, Galit Alter, Dusan Bogunovic, David O'Neill, Sylvia Adams, Anna Pavlick, Bruce D. Walker, Mark A. Brockman, Rajesh T. Gandhi, and Nina Bhardwaj
Cancer Res 2008 68: 9441-9450. doi: 10.1158/0008-5472.CAN-08-0900 [Abstract] [Full Text] [PDF] Supplementary Data  

Melanoma-Specific Memory T Cells Are Functionally Active in Ret Transgenic Mice without Macroscopic Tumors

Viktor Umansky, Oliver Abschuetz, Wolfram Osen, Marcel Ramacher, Fang Zhao, Masashi Kato, and Dirk Schadendorf
Cancer Res 2008 68: 9451-9458. doi: 10.1158/0008-5472.CAN-08-1464 [Abstract] [Full Text] [PDF]  

Regulated Expression of a Tumor-Associated Antigen Reveals Multiple Levels of T-Cell Tolerance in a Mouse Model of Lung Cancer

Ann F. Cheung, Michel J.P. DuPage, H. Katie Dong, Jianzhu Chen, and Tyler Jacks
Cancer Res 2008 68: 9459-9468. doi: 10.1158/0008-5472.CAN-08-2634 [Abstract] [Full Text] [PDF] Supplementary Data  

Molecular Biology, Pathobiology, and Genetics:

Posttranscriptional Regulation of the Breast Cancer Susceptibility Gene BRCA1 by the RNA Binding Protein HuR

Jodi M. Saunus, Juliet D. French, Stacey L. Edwards, Dianne J. Beveridge, Esme C. Hatchell, Sarah A. Wagner, Sandra R. Stein, Andrew Davidson, Kaylene J. Simpson, Glenn D. Francis, Peter J. Leedman, and Melissa A. Brown
Cancer Res 2008 68: 9469-9478. doi: 10.1158/0008-5472.CAN-08-1159 [Abstract] [Full Text] [PDF]  

Hepatocyte Growth Factor Induces Gefitinib Resistance of Lung Adenocarcinoma with Epidermal Growth Factor Receptor–Activating Mutations

Seiji Yano, Wei Wang, Qi Li, Kunio Matsumoto, Haruko Sakurama, Takahiro Nakamura, Hirokazu Ogino, Soji Kakiuchi, Masaki Hanibuchi, Yasuhiko Nishioka, Hisanori Uehara, Tetsuya Mitsudomi, Yasushi Yatabe, Toshikazu Nakamura, and Saburo Sone
Cancer Res 2008 68: 9479-9487. doi: 10.1158/0008-5472.CAN-08-1643 [Abstract] [Full Text] [PDF] Supplementary Data  

A Novel Mechanism of Late Gene Silencing Drives SV40 Transformation of Human Mesothelial Cells

Michele Carbone, Antonio Pannuti, Lei Zhang, Joseph R. Testa, and Maurizio Bocchetta
Cancer Res 2008 68: 9488-9496. doi: 10.1158/0008-5472.CAN-08-2332 [Abstract] [Full Text] [PDF] Supplementary Data  

Ku80 Deletion Suppresses Spontaneous Tumors and Induces a p53-Mediated DNA Damage Response

Valerie B. Holcomb, Francis Rodier, YongJun Choi, Rita A. Busuttil, Hannes Vogel, Jan Vijg, Judith Campisi, and Paul Hasty
Cancer Res 2008 68: 9497-9502. doi: 10.1158/0008-5472.CAN-08-2085 [Abstract] [Full Text] [PDF]  

Prevention:

Garlic Constituent Diallyl Trisulfide Prevents Development of Poorly Differentiated Prostate Cancer and Pulmonary Metastasis Multiplicity in TRAMP Mice

Shivendra V. Singh, Anna A. Powolny, Silvia D. Stan, Dong Xiao, Julie A. Arlotti, Renaud Warin, Eun-Ryeong Hahm, Stanley W. Marynowski, Ajay Bommareddy, Douglas M. Potter, and Rajiv Dhir
Cancer Res 2008 68: 9503-9511. doi: 10.1158/0008-5472.CAN-08-1677 [Abstract] [Full Text] [PDF]  

Effect of Fenretinide and Low-Dose Tamoxifen on Insulin Sensitivity in Premenopausal Women at High Risk for Breast Cancer

Harriet Johansson, Sara Gandini, Aliana Guerrieri-Gonzaga, Simona Iodice, Massimiliano Ruscica, Bernardo Bonanni, Marcella Gulisano, Paolo Magni, Franca Formelli, and Andrea Decensi
Cancer Res 2008 68: 9512-9518. doi: 10.1158/0008-5472.CAN-08-0553 [Abstract] [Full Text] [PDF]  

Systems Biology and Emerging Technologies:

IB Kinase Inhibitor IKI-1 Conferred Tumor Necrosis Factor Sensitivity to Pancreatic Cancer Cells and a Xenograft Tumor Model

Yixian Zhang, Maria Gavriil, Judy Lucas, Sreekala Mandiyan, Max Follettie, Veronica Diesl, Fuk-Wah Sum, Dennis Powell, Steve Haney, Robert Abraham, and Kim Arndt
Cancer Res 2008 68: 9519-9524. doi: 10.1158/0008-5472.CAN-08-1549 [Abstract] [Full Text] [PDF] Supplementary Data  

Identification of Alternative Splicing Markers for Breast Cancer

Julian P. Venables, Roscoe Klinck, Anne Bramard, Lyna Inkel, Geneviève Dufresne-Martin, ChuShin Koh, Julien Gervais-Bird, Elvy Lapointe, Ulrike Froehlich, Mathieu Durand, Daniel Gendron, Jean-Philippe Brosseau, Philippe Thibault, Jean-Francois Lucier, Karine Tremblay, Panagiotis Prinos, Raymund J. Wellinger, Benoit Chabot, Claudine Rancourt, and Sherif Abou Elela
Cancer Res 2008 68: 9525-9531. doi: 10.1158/0008-5472.CAN-08-1769 [Abstract] [Full Text] [PDF] Supplementary Data  

Genome-Wide Functional Synergy between Amplified and Mutated Genes in Human Breast Cancer

Yuri Nikolsky, Evgeny Sviridov, Jun Yao, Damir Dosymbekov, Vadim Ustyansky, Valery Kaznacheev, Zoltan Dezso, Laura Mulvey, Laura E. Macconaill, Wendy Winckler, Tatiana Serebryiskaya, Tatiana Nikolskaya, and Kornelia Polyak
Cancer Res 2008 68: 9532-9540. doi: 10.1158/0008-5472.CAN-08-3082 [Abstract] [Full Text] [PDF] Supplementary Data  

Tumor Microenvironment:

ADAMTS-1 Metalloproteinase Promotes Tumor Development through the Induction of a Stromal Reaction In vivo

Natacha Rocks, Geneviève Paulissen, Florence Quesada-Calvo, Carine Munaut, Maria-Luz Alvarez Gonzalez, Maud Gueders, Jonathan Hacha, Christine Gilles, Jean-Michel Foidart, Agnès Noel, and Didier D. Cataldo
Cancer Res 2008 68: 9541-9550. doi: 10.1158/0008-5472.CAN-08-0548 [Abstract] [Full Text] [PDF]  

Palomid 529, a Novel Small-Molecule Drug, Is a TORC1/TORC2 Inhibitor That Reduces Tumor Growth, Tumor Angiogenesis, and Vascular Permeability

Qi Xue, Benjamin Hopkins, Carole Perruzzi, Durga Udayakumar, David Sherris, and Laura E. Benjamin
Cancer Res 2008 68: 9551-9557. doi: 10.1158/0008-5472.CAN-08-2058 [Abstract] [Full Text] [PDF] Supplementary Data  

Membrane Type 1 Matrix Metalloproteinase–Mediated Stromal Syndecan-1 Shedding Stimulates Breast Carcinoma Cell Proliferation

Gui Su, Stacy A. Blaine, Dianhua Qiao, and Andreas Friedl
Cancer Res 2008 68: 9558-9565. doi: 10.1158/0008-5472.CAN-08-1645 [Abstract] [Full Text] [PDF] Supplementary Data  

Corrections:

Correction: IGF-IR/HER-2 Contributes to Trastuzumab Resistance

Cancer Res 2008 68: 9566. doi: 10.1158/0008-5472.CAN-68-22-COR1 [Full Text] [PDF]  

Correction: PDGFB-Mediated Model of Spinal Glioma

Cancer Res 2008 68: 9566. doi: 10.1158/0008-5472.CAN-68-22-COR2 [Full Text] [PDF]  

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