Reviews:

Regulation of Cancer Cell Survival, Migration, and Invasion by Twist: AKT2 Comes to Interplay

George Z. Cheng, Weizhou Zhang, and Lu-Hai Wang
Cancer Res 2008 68: 957-960. doi: 10.1158/0008-5472.CAN-07-5067 [Abstract] [Full Text] [PDF]  

Stroma-Initiated Hedgehog Signaling Takes Center Stage in B-Cell Lymphoma

Ralph K. Lindemann
Cancer Res 2008 68: 961-964. doi: 10.1158/0008-5472.CAN-07-5500 [Abstract] [Full Text] [PDF]  

Priority Reports:

A Functional Role for KLF6-SV1 in Lung Adenocarcinoma Prognosis and Chemotherapy Response

Analisa DiFeo, Lauren Feld, Estefania Rodriguez, Christine Wang, David G. Beer, John A. Martignetti, and Goutham Narla
Cancer Res 2008 68: 965-970. Published Online First February 4, 2008. doi: 10.1158/0008-5472.CAN-07-2604 [Abstract] [Full Text] [PDF]  

Mutational Analysis of Thirty-two Double-Strand DNA Break Repair Genes in Breast and Pancreatic Cancers

Xianshu Wang, Csilla Szabo, Chiping Qian, Peter G. Amadio, Stephen N. Thibodeau, James R. Cerhan, Gloria M. Petersen, Wanguo Liu, and Fergus J. Couch
Cancer Res 2008 68: 971-975. doi: 10.1158/0008-5472.CAN-07-6272 [Abstract] [Full Text] [PDF] Supplementary Data  

FcRIIIa Expression Is Not Increased on Natural Killer Cells Expressing the FcRIIIa-158V Allotype

Nicolas Congy-Jolivet, Armelle Bolzec, David Ternant, Marc Ohresser, Herve Watier, and Gilles Thibault
Cancer Res 2008 68: 976-980. doi: 10.1158/0008-5472.CAN-07-6523 [Abstract] [Full Text] [PDF]  

Molecular Biology, Pathobiology, and Genetics:

Growth Suppression of Lung Cancer Cells by Targeting Cyclic AMP Response Element-Binding Protein

Sita Aggarwal, Seung-Wook Kim, Seung-Hee Ryu, Wen-Cheng Chung, and Ja Seok Koo
Cancer Res 2008 68: 981-988. doi: 10.1158/0008-5472.CAN-06-0249 [Abstract] [Full Text] [PDF]  

Epithelial-Mesenchymal Transition in Breast Cancer Relates to the Basal-like Phenotype

David Sarrió, Socorro María Rodriguez-Pinilla, David Hardisson, Amparo Cano, Gema Moreno-Bueno, and José Palacios
Cancer Res 2008 68: 989-997. doi: 10.1158/0008-5472.CAN-07-2017 [Abstract] [Full Text] [PDF] Supplementary Data  

Promoter Hypermethylation of the PALB2 Susceptibility Gene in Inherited and Sporadic Breast and Ovarian Cancer

Anna Potapova, Amanda M. Hoffman, Andrew K. Godwin, Tahseen Al-Saleem, and Paul Cairns
Cancer Res 2008 68: 998-1002. doi: 10.1158/0008-5472.CAN-07-2418 [Abstract] [Full Text] [PDF] Supplementary Data  

Fatty Acid Synthase Gene Is Up-regulated by Hypoxia via Activation of Akt and Sterol Regulatory Element Binding Protein-1

Eiji Furuta, Sudha K. Pai, Rui Zhan, Sucharita Bandyopadhyay, Misako Watabe, Yin-Yuan Mo, Shigeru Hirota, Sadahiro Hosobe, Taisei Tsukada, Kunio Miura, Shuichi Kamada, Ken Saito, Megumi Iiizumi, Wen Liu, Johan Ericsson, and Kounosuke Watabe
Cancer Res 2008 68: 1003-1011. doi: 10.1158/0008-5472.CAN-07-2489 [Abstract] [Full Text] [PDF]  

Integrated Genomic Profiling of Chronic Lymphocytic Leukemia Identifies Subtypes of Deletion 13q14

Peter Ouillette, Harry Erba, Lisa Kujawski, Mark Kaminski, Kerby Shedden, and Sami N. Malek
Cancer Res 2008 68: 1012-1021. doi: 10.1158/0008-5472.CAN-07-3105 [Abstract] [Full Text] [PDF] Supplementary Data  

The SV40 Large T Antigen-p53 Complexes Bind and Activate the Insulin-like Growth Factor-I Promoter Stimulating Cell Growth

Maurizio Bocchetta, Sandra Eliasz, Melissa Arakelian De Marco, Jennifer Rudzinski, Lei Zhang, and Michele Carbone
Cancer Res 2008 68: 1022-1029. doi: 10.1158/0008-5472.CAN-07-5203 [Abstract] [Full Text] [PDF] Supplementary Data  

Reconstitution of Nasopharyngeal Carcinoma–Type EBV Infection Induces Tumorigenicity

Eri Seto, Tadamasa Ooka, Jaap Middeldorp, and Kenzo Takada
Cancer Res 2008 68: 1030-1036. doi: 10.1158/0008-5472.CAN-07-5252 [Abstract] [Full Text] [PDF] Supplementary Data  

Silencing of DUOX NADPH Oxidases by Promoter Hypermethylation in Lung Cancer

Sylvia Luxen, Steven A. Belinsky, and Ulla G. Knaus
Cancer Res 2008 68: 1037-1045. doi: 10.1158/0008-5472.CAN-07-5782 [Abstract] [Full Text] [PDF] Supplementary Data  

Nucleolin Stabilizes Bcl-X_L Messenger RNA in Response to UVA Irradiation

Jack Zhang, George Tsaprailis, and G. Tim Bowden
Cancer Res 2008 68: 1046-1054. doi: 10.1158/0008-5472.CAN-07-1927 [Abstract] [Full Text] [PDF]  

Human Peroxiredoxin PrxI Is an Orthologue of Yeast Tsa1, Capable of Suppressing Genome Instability in Saccharomyces cerevisiae

Ismail Iraqui, Gérard Faye, Sandrine Ragu, Amélie Masurel-Heneman, Richard D. Kolodner, and Meng-Er Huang
Cancer Res 2008 68: 1055-1063. doi: 10.1158/0008-5472.CAN-07-2683 [Abstract] [Full Text] [PDF]  

Use of a Cryptic Splice Site for the Expression of Huntingtin Interacting Protein 1 in Select Normal and Neoplastic Tissues

Chiron W. Graves, Steven T. Philips, Sarah V. Bradley, Katherine I. Oravecz-Wilson, Lina Li, Alice Gauvin, and Theodora S. Ross
Cancer Res 2008 68: 1064-1073. doi: 10.1158/0008-5472.CAN-07-5892 [Abstract] [Full Text] [PDF] Supplementary Data  

Cell, Tumor, and Stem Cell Biology:

Efficient Identification of a Novel Cancer/Testis Antigen for Immunotherapy Using Three-Step Microarray Analysis

Takeshi Yokoe, Fumiaki Tanaka, Koshi Mimori, Hiroshi Inoue, Takahiro Ohmachi, Masato Kusunoki, and Masaki Mori
Cancer Res 2008 68: 1074-1082. doi: 10.1158/0008-5472.CAN-07-0964 [Abstract] [Full Text] [PDF]  

Differential Effects of Interleukin-2 and Interleukin-15 versus Interleukin-21 on CD4+ Cutaneous T-Cell Lymphoma Cells

Michal Marzec, Krzysztof Halasa, Monika Kasprzycka, Maria Wysocka, Xiaobin Liu, John W. Tobias, Donald Baldwin, Qian Zhang, Niels Odum, Alain H. Rook, and Mariusz A. Wasik
Cancer Res 2008 68: 1083-1091. doi: 10.1158/0008-5472.CAN-07-2403 [Abstract] [Full Text] [PDF]  

ADAM15 Supports Prostate Cancer Metastasis by Modulating Tumor Cell–Endothelial Cell Interaction

Abdo J. Najy, Kathleen C. Day, and Mark L. Day
Cancer Res 2008 68: 1092-1099. doi: 10.1158/0008-5472.CAN-07-2432 [Abstract] [Full Text] [PDF] Supplementary Data  

Profound but Dysfunctional Lymphangiogenesis via Vascular Endothelial Growth Factor Ligands from CD11b⁺ Macrophages in Advanced Ovarian Cancer

Bong-Hyun Jeon, Cholsoon Jang, Jinah Han, Raghu P. Kataru, Lianhua Piao, Keehoon Jung, Hye Ji Cha, Reto A. Schwendener, Kyu Yun Jang, Kwan-Sik Kim, Kari Alitalo, and Gou Young Koh
Cancer Res 2008 68: 1100-1109. doi: 10.1158/0008-5472.CAN-07-2572 [Abstract] [Full Text] [PDF] Supplementary Data  

The Differential Role of L1 in Ovarian Carcinoma and Normal Ovarian Surface Epithelium

Silvia Zecchini, Marco Bianchi, Nicoletta Colombo, Roberta Fasani, Giovanni Goisis, Chiara Casadio, Giuseppe Viale, Jinsong Liu, Meenhard Herlyn, Andrew K. Godwin, Paolo G. Nuciforo, and Ugo Cavallaro
Cancer Res 2008 68: 1110-1118. doi: 10.1158/0008-5472.CAN-07-2897 [Abstract] [Full Text] [PDF] Supplementary Data  

Pten Inactivation Accelerates Oncogenic K-ras–Initiated Tumorigenesis in a Mouse Model of Lung Cancer

Kentaro Iwanaga, Yanan Yang, Maria Gabriela Raso, Lijiang Ma, Amy E. Hanna, Nishan Thilaganathan, Seyed Moghaddam, Christopher M. Evans, Huaiguang Li, Wei-Wen Cai, Mitsuo Sato, John D. Minna, Hong Wu, Chad J. Creighton, Francesco J. Demayo, Ignacio I. Wistuba, and Jonathan M. Kurie
Cancer Res 2008 68: 1119-1127. doi: 10.1158/0008-5472.CAN-07-3117 [Abstract] [Full Text] [PDF] Supplementary Data  

Androgen Receptor and Invasion in Prostate Cancer

Takahito Hara, Hideyo Miyazaki, Aram Lee, Chau P. Tran, and Robert E. Reiter
Cancer Res 2008 68: 1128-1135. doi: 10.1158/0008-5472.CAN-07-1929 [Abstract] [Full Text] [PDF] Supplementary Data  

Negative Feedback Regulation of IFN- Pathway by IFN Regulatory Factor 2 in Esophageal Cancers

Yan Wang, Dongping Liu, Pingping Chen, H. Phillip Koeffler, Xiangjun Tong, and Dong Xie
Cancer Res 2008 68: 1136-1143. doi: 10.1158/0008-5472.CAN-07-5021 [Abstract] [Full Text] [PDF] Supplementary Data  

Experimental Therapeutics, Molecular Targets, and Chemical Biology:

A Retroinhibition Approach Reveals a Tumor Cell–Autonomous Response to Rapamycin in Head and Neck Cancer

Panomwat Amornphimoltham, Vyomesh Patel, Kantima Leelahavanichkul, Robert T. Abraham, and J. Silvio Gutkind
Cancer Res 2008 68: 1144-1153. doi: 10.1158/0008-5472.CAN-07-1756 [Abstract] [Full Text] [PDF] Supplementary Data  

Synergistic Damage of Tumor Vessels with Ultra Low-Dose Endothelial-Monocyte Activating Polypeptide-II and Neovasculature-Targeted Tumor Necrosis Factor-

Luca Crippa, Anna Gasparri, Angelina Sacchi, Elisabetta Ferrero, Flavio Curnis, and Angelo Corti
Cancer Res 2008 68: 1154-1161. doi: 10.1158/0008-5472.CAN-07-2085 [Abstract] [Full Text] [PDF]  

A Selective Phosphatase of Regenerating Liver Phosphatase Inhibitor Suppresses Tumor Cell Anchorage-Independent Growth by a Novel Mechanism Involving p130Cas Cleavage

Sherif Daouti, Wen-hui Li, Hong Qian, Kuo-Sen Huang, Janna Holmgren, Wayne Levin, Linda Reik, Debra Lucas McGady, Paul Gillespie, Agostino Perrotta, Hongjin Bian, John F. Reidhaar-Olson, Sarah A. Bliss, Andree R. Olivier, Joseph A. Sergi, David Fry, Waleed Danho, Steve Ritland, Nader Fotouhi, David Heimbrook, and Huifeng Niu
Cancer Res 2008 68: 1162-1169. doi: 10.1158/0008-5472.CAN-07-2349 [Abstract] [Full Text] [PDF]  

Tissue Inhibitor of Metalloproteinase-3 via Oncolytic Herpesvirus Inhibits Tumor Growth and Vascular Progenitors

Yonatan Y. Mahller, Sachin S. Vaikunth, Maria C. Ripberger, William H. Baird, Yoshinaga Saeki, Jose A. Cancelas, Timothy M. Crombleholme, and Timothy P. Cripe
Cancer Res 2008 68: 1170-1179. doi: 10.1158/0008-5472.CAN-07-2734 [Abstract] [Full Text] [PDF] Supplementary Data  

Acetyl-Keto-β-Boswellic Acid Induces Apoptosis through a Death Receptor 5–Mediated Pathway in Prostate Cancer Cells

Min Lu, Lijuan Xia, Huiming Hua, and Yongkui Jing
Cancer Res 2008 68: 1180-1186. doi: 10.1158/0008-5472.CAN-07-2978 [Abstract] [Full Text] [PDF]  

Silencing of HSP90 Cochaperone AHA1 Expression Decreases Client Protein Activation and Increases Cellular Sensitivity to the HSP90 Inhibitor 17-Allylamino-17-Demethoxygeldanamycin

Joanna L. Holmes, Swee Y. Sharp, Steve Hobbs, and Paul Workman
Cancer Res 2008 68: 1188-1197. doi: 10.1158/0008-5472.CAN-07-3268 [Abstract] [Full Text] [PDF] Supplementary Data  

TREK-1 Is a Novel Molecular Target in Prostate Cancer

Iryna Voloshyna, Alessandra Besana, Mireia Castillo, Tulio Matos, I. Bernard Weinstein, Mahesh Mansukhani, Richard B. Robinson, Carlos Cordon-Cardo, and Steven J. Feinmark
Cancer Res 2008 68: 1197-1203. doi: 10.1158/0008-5472.CAN-07-5163 [Abstract] [Full Text] [PDF]  

FTY720 Induces Apoptosis in Hepatocellular Carcinoma Cells through Activation of Protein Kinase C Signaling

Jui-Hsiang Hung, Yen-Shen Lu, Yu-Chieh Wang, Yi-Hui Ma, Da-Sheng Wang, Samuel K. Kulp, Natarajan Muthusamy, John C. Byrd, Ann-Lii Cheng, and Ching-Shih Chen
Cancer Res 2008 68: 1204-1212. doi: 10.1158/0008-5472.CAN-07-2621 [Abstract] [Full Text] [PDF]  

Cyclooxygenase-2 Inhibition Inhibits c-Met Kinase Activity and Wnt Activity in Colon Cancer

Jurriaan B. Tuynman, Louis Vermeulen, Elles M. Boon, Kristel Kemper, Aeilko H. Zwinderman, Maikel P. Peppelenbosch, and Dirk J. Richel
Cancer Res 2008 68: 1213-1220. doi: 10.1158/0008-5472.CAN-07-5172 [Abstract] [Full Text] [PDF]  

Construction of Optimized Bispecific Antibodies for Selective Activation of the Death Receptor CD95

Tanja Herrmann, Ludger Große-Hovest, Tina Otz, Peter H. Krammer, Hans-Georg Rammensee, and Gundram Jung
Cancer Res 2008 68: 1221-1227. doi: 10.1158/0008-5472.CAN-07-6175 [Abstract] [Full Text] [PDF]  

Immunology:

Targeting Tumor Antigens to Secreted Membrane Vesicles In vivo Induces Efficient Antitumor Immune Responses

Ingrid S. Zeelenberg, Matias Ostrowski, Sophie Krumeich, Angélique Bobrie, Carolina Jancic, Alexandre Boissonnas, Alain Delcayre, Jean-Bernard Le Pecq, Béhazine Combadière, Sebastian Amigorena, and Clotilde Théry
Cancer Res 2008 68: 1228-1235. doi: 10.1158/0008-5472.CAN-07-3163 [Abstract] [Full Text] [PDF] Supplementary Data  

Epidemiology:

Association of Genetic Variation in the Transforming Growth Factor β-1 Gene with Serum Levels and Risk of Colorectal Neoplasia

Barbara S. Saltzman, Jennifer F. Yamamoto, Robert Decker, Lance Yokochi, Andre G. Theriault, Thomas M. Vogt, and Loïc Le Marchand
Cancer Res 2008 68: 1236-1244. doi: 10.1158/0008-5472.CAN-07-2144 [Abstract] [Full Text] [PDF] Supplementary Data  

Corrections:

Correction: The FBXW7 Gene Is Mutated in a Variety of Human Tumors

Cancer Res 2008 68: 1245 [Full Text] [PDF]  

Correction: BARD1 Isoforms in Cancer

Cancer Res 2008 68: 1245 [Full Text] [PDF]  

Correction: Melanoma Stem Cell Hypothesis

Cancer Res 2008 68: 1245 [Full Text] [PDF]  

Correction: The NCI-60: Ionizing Radiation and Gene Expression

Cancer Res 2008 68: 1245 [Full Text] [PDF]  

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