Reviews:

The Quest for the 1p36 Tumor Suppressor

Anindya Bagchi and Alea A. Mills
Cancer Res 2008 68: 2551-2556. doi: 10.1158/0008-5472.CAN-07-2095 [Abstract] [Full Text] [PDF]  

Role of the Aggresome Pathway in Cancer: Targeting Histone Deacetylase 6–Dependent Protein Degradation

Agustin Rodriguez-Gonzalez, Tara Lin, Alan K. Ikeda, Tiffany Simms-Waldrip, Cecilia Fu, and Kathleen M. Sakamoto
Cancer Res 2008 68: 2557-2560. doi: 10.1158/0008-5472.CAN-07-5989 [Abstract] [Full Text] [PDF]  

Tumor Escape Mechanism Governed by Myeloid-Derived Suppressor Cells

Srinivas Nagaraj and Dmitry I. Gabrilovich
Cancer Res 2008 68: 2561-2563. doi: 10.1158/0008-5472.CAN-07-6229 [Abstract] [Full Text] [PDF]  

Priority Reports:

Identification of p18^INK4c as a Tumor Suppressor Gene in Glioblastoma Multiforme

David A. Solomon, Jung-Sik Kim, Sultan Jenkins, Habtom Ressom, Michael Huang, Nicholas Coppa, Lauren Mabanta, Darell Bigner, Hai Yan, Walter Jean, and Todd Waldman
Cancer Res 2008 68: 2564-2569. Published Online First April 1, 2008. doi: 10.1158/0008-5472.CAN-07-6388 [Abstract] [Full Text] [PDF] Supplementary Data  

A Requirement for DICER to Maintain Full Promoter CpG Island Hypermethylation in Human Cancer Cells

Angela H. Ting, Hiromu Suzuki, Leslie Cope, Kornel E. Schuebel, Byron H. Lee, Minoru Toyota, Kohzoh Imai, Yasuhisa Shinomura, Takashi Tokino, and Stephen B. Baylin
Cancer Res 2008 68: 2570-2575. doi: 10.1158/0008-5472.CAN-07-6405 [Abstract] [Full Text] [PDF] Supplementary Data  

BCR/ABL Inhibits Mismatch Repair to Protect from Apoptosis and Induce Point Mutations

Tomasz Stoklosa, Tomasz Poplawski, Mateusz Koptyra, Margaret Nieborowska-Skorska, Grzegorz Basak, Artur Slupianek, Marina Rayevskaya, Ilona Seferynska, Larry Herrera, Janusz Blasiak, and Tomasz Skorski
Cancer Res 2008 68: 2576-2580. doi: 10.1158/0008-5472.CAN-07-6858 [Abstract] [Full Text] [PDF] Supplementary Data  

Secondary BRCA1 Mutations in BRCA1-Mutated Ovarian Carcinomas with Platinum Resistance

Elizabeth M. Swisher, Wataru Sakai, Beth Y. Karlan, Kaitlyn Wurz, Nicole Urban, and Toshiyasu Taniguchi
Cancer Res 2008 68: 2581-2586. doi: 10.1158/0008-5472.CAN-08-0088 [Abstract] [Full Text] [PDF] Supplementary Data  

Identification of Let-7–Regulated Oncofetal Genes

Benjamin Boyerinas, Sun-Mi Park, Noam Shomron, Mads M. Hedegaard, Jeppe Vinther, Jens S. Andersen, Christine Feig, Jinbo Xu, Christopher B. Burge, and Marcus E. Peter
Cancer Res 2008 68: 2587-2591. doi: 10.1158/0008-5472.CAN-08-0264 [Abstract] [Full Text] [PDF] Supplementary Data  

Molecular Biology, Pathobiology, and Genetics:

A Role for TAZ in Migration, Invasion, and Tumorigenesis of Breast Cancer Cells

Siew Wee Chan, Chun Jye Lim, Ke Guo, Chee Peng Ng, Ian Lee, Walter Hunziker, Qi Zeng, and Wanjin Hong
Cancer Res 2008 68: 2592-2598. doi: 10.1158/0008-5472.CAN-07-2696 [Abstract] [Full Text] [PDF] Supplementary Data  

Cyclin D1 and CDK4 Activity Contribute to the Undifferentiated Phenotype in Neuroblastoma

Jan J. Molenaar, Marli E. Ebus, Jan Koster, Peter van Sluis, Carel J.M. van Noesel, Rogier Versteeg, and Huib N. Caron
Cancer Res 2008 68: 2599-2609. doi: 10.1158/0008-5472.CAN-07-5032 [Abstract] [Full Text] [PDF]  

The Signatures of Autozygosity among Patients with Colorectal Cancer

Manny D. Bacolod, Gunter S. Schemmann, Shuang Wang, Richard Shattock, Sarah F. Giardina, Zhaoshi Zeng, Jinru Shia, Robert F. Stengel, Norman Gerry, Josephine Hoh, Tomas Kirchhoff, Bert Gold, Michael F. Christman, Kenneth Offit, William L. Gerald, Daniel A. Notterman, Jurg Ott, Philip B. Paty, and Francis Barany
Cancer Res 2008 68: 2610-2621. Published Online First March 28, 2008. doi: 10.1158/0008-5472.CAN-07-5250 [Abstract] [Full Text] [PDF] Supplementary Data  

p53 Loss Synergizes with Estrogen and Papillomaviral Oncogenes to Induce Cervical and Breast Cancers

Anny Shai, Henry C. Pitot, and Paul F. Lambert
Cancer Res 2008 68: 2622-2631. doi: 10.1158/0008-5472.CAN-07-5266 [Abstract] [Full Text] [PDF] Supplementary Data  

Bile Acid Exposure Up-regulates Tuberous Sclerosis Complex 1/Mammalian Target of Rapamycin Pathway in Barrett's-Associated Esophageal Adenocarcinoma

Chia-Jui Yen, Julie G. Izzo, Dung-Fang Lee, Sushovan Guha, Yongkun Wei, Tsung-Teh Wu, Chun-Te Chen, Hsu-Ping Kuo, Jung-Mao Hsu, Hui-Lung Sun, Chao-Kai Chou, Navtej S. Buttar, Kenneth K. Wang, Peng Huang, Jaffer Ajani, and Mien-Chie Hung
Cancer Res 2008 68: 2632-2640. doi: 10.1158/0008-5472.CAN-07-5460 [Abstract] [Full Text] [PDF]  

Analysis of the Mechanisms Mediating Tumor-Specific Changes in Gene Expression in Human Liver Tumors

Luis G. Acevedo, Mark Bieda, Roland Green, and Peggy J. Farnham
Cancer Res 2008 68: 2641-2651. doi: 10.1158/0008-5472.CAN-07-5590 [Abstract] [Full Text] [PDF] Supplementary Data  

Broad Overexpression of Ribonucleotide Reductase Genes in Mice Specifically Induces Lung Neoplasms

Xia Xu, Jennifer L. Page, Jennifer A. Surtees, Houchun Liu, Sarah Lagedrost, Young Lu, Roderick Bronson, Eric Alani, Alexander Yu. Nikitin, and Robert S. Weiss
Cancer Res 2008 68: 2652-2660. doi: 10.1158/0008-5472.CAN-07-5873 [Abstract] [Full Text] [PDF] Supplementary Data  

Genome-Wide Promoter Analysis Uncovers Portions of the Cancer Methylome

Mohammad Obaidul Hoque, Myoung Sook Kim, Kimberly Laskie Ostrow, Junwei Liu, G. Bea A. Wisman, Hannah Lui Park, Maria Luana Poeta, Carmen Jeronimo, Rui Henrique, Ágnes Lendvai, Ed Schuuring, Shahnaz Begum, Eli Rosenbaum, Maté Ongenaert, Keishi Yamashita, Joseph Califano, William Westra, Ate G.J. van der Zee, Wim Van Criekinge, and David Sidransky
Cancer Res 2008 68: 2661-2670. doi: 10.1158/0008-5472.CAN-07-5913 [Abstract] [Full Text] [PDF] Supplementary Data  

Targeted Deletion of Prkar1a Reveals a Role for Protein Kinase A in Mesenchymal-to-Epithelial Transition

Kiran S. Nadella, Georgette N. Jones, Anthony Trimboli, Constantine A. Stratakis, Gustavo Leone, and Lawrence S. Kirschner
Cancer Res 2008 68: 2671-2677. doi: 10.1158/0008-5472.CAN-07-6002 [Abstract] [Full Text] [PDF] Supplementary Data  

Androgen Receptor Overexpression in Prostate Cancer Linked to Pur Loss from a Novel Repressor Complex

Longgui G. Wang, Edward M. Johnson, Yayoi Kinoshita, James S. Babb, Michael T. Buckley, Leonard F. Liebes, Jonathan Melamed, Xiao-Mei Liu, Ralf Kurek, Liliana Ossowski, and Anna C. Ferrari
Cancer Res 2008 68: 2678-2688. doi: 10.1158/0008-5472.CAN-07-6017 [Abstract] [Full Text] [PDF]  

Novel and Highly Recurrent Chromosomal Alterations in Sézary Syndrome

Maarten H. Vermeer, Remco van Doorn, Remco Dijkman, Xin Mao, Sean Whittaker, Pieter C. van Voorst Vader, Marie-Jeanne P. Gerritsen, Marie-Louise Geerts, Sylke Gellrich, Ola Söderberg, Karl-Johan Leuchowius, Ulf Landegren, Jacoba J. Out-Luiting, Jeroen Knijnenburg, Marije IJszenga, Karoly Szuhai, Rein Willemze, and Cornelis P. Tensen
Cancer Res 2008 68: 2689-2698. doi: 10.1158/0008-5472.CAN-07-6398 [Abstract] [Full Text] [PDF] Supplementary Data  

Distinct RAD51 Associations with RAD52 and BCCIP in Response to DNA Damage and Replication Stress

Justin Wray, Jingmei Liu, Jac A. Nickoloff, and Zhiyuan Shen
Cancer Res 2008 68: 2699-2707. doi: 10.1158/0008-5472.CAN-07-6505 [Abstract] [Full Text] [PDF] Supplementary Data  

MUC1 Expression Is Regulated by DNA Methylation and Histone H3 Lysine 9 Modification in Cancer Cells

Norishige Yamada, Yukari Nishida, Hideaki Tsutsumida, Tomofumi Hamada, Masamichi Goto, Michiyo Higashi, Mitsuharu Nomoto, and Suguru Yonezawa
Cancer Res 2008 68: 2708-2716. doi: 10.1158/0008-5472.CAN-07-6844 [Abstract] [Full Text] [PDF]  

Breast Carcinoma–Associated Fibroblasts and Their Counterparts Display Neoplastic-Specific Changes

Nahed M. Hawsawi, Hazem Ghebeh, Siti-Faujiah Hendrayani, Asma Tulbah, Maha Al-Eid, Taher Al-Tweigeri, Dahish Ajarim, Ayodele Alaiya, Said Dermime, and Abdelilah Aboussekhra
Cancer Res 2008 68: 2717-2725. doi: 10.1158/0008-5472.CAN-08-0192 [Abstract] [Full Text] [PDF]  

DNA Methyltransferase 1 and 3B Activate BAG-1 Expression via Recruitment of CTCFL/BORIS and Modulation of Promoter Histone Methylation

Lunching Sun, Lei Huang, Phuongmai Nguyen, Kheem S. Bisht, Gil Bar-Sela, Allen S. Ho, C. Matthew Bradbury, Wenqiang Yu, Hengmi Cui, Sunmin Lee, Jane B. Trepel, Andrew P. Feinberg, and David Gius
Cancer Res 2008 68: 2726-2735. doi: 10.1158/0008-5472.CAN-07-6654 [Abstract] [Full Text] [PDF] Supplementary Data  

Cell, Tumor, and Stem Cell Biology:

Genistein Induces the p21WAF1/CIP1 and p16INK4a Tumor Suppressor Genes in Prostate Cancer Cells by Epigenetic Mechanisms Involving Active Chromatin Modification

Shahana Majid, Nobuyuki Kikuno, Jason Nelles, Emily Noonan, Yuichiro Tanaka, Ken Kawamoto, Hiroshi Hirata, Long C. Li, Hong Zhao, Steve T. Okino, Robert F. Place, Deepa Pookot, and Rajvir Dahiya
Cancer Res 2008 68: 2736-2744. doi: 10.1158/0008-5472.CAN-07-2290 [Abstract] [Full Text] [PDF]  

The Promyelocytic Leukemia Zinc Finger–MicroRNA-221/-222 Pathway Controls Melanoma Progression through Multiple Oncogenic Mechanisms

Federica Felicetti, M. Cristina Errico, Lisabianca Bottero, Patrizia Segnalini, Antonella Stoppacciaro, Mauro Biffoni, Nadia Felli, Gianfranco Mattia, Marina Petrini, Mario P. Colombo, Cesare Peschle, and Alessandra Carè
Cancer Res 2008 68: 2745-2754. doi: 10.1158/0008-5472.CAN-07-2538 [Abstract] [Full Text] [PDF] Supplementary Data  

Matrix Metalloproteinase-8 Functions as a Metastasis Suppressor through Modulation of Tumor Cell Adhesion and Invasion

Ana Gutiérrez-Fernández, Antonio Fueyo, Alicia R. Folgueras, Cecilia Garabaya, Caroline J. Pennington, Simon Pilgrim, Dylan R. Edwards, Deborah L. Holliday, J. Louise Jones, Paul N. Span, Fred C.G.J. Sweep, Xose S. Puente, and Carlos López-Otín
Cancer Res 2008 68: 2755-2763. doi: 10.1158/0008-5472.CAN-07-5154 [Abstract] [Full Text] [PDF] Supplementary Data  

Epigenetic Inactivation of the Canonical Wnt Antagonist SRY-Box Containing Gene 17 in Colorectal Cancer

Wei Zhang, Sabine C. Glöckner, Mingzhou Guo, Emi Ota Machida, David H. Wang, Hariharan Easwaran, Leander Van Neste, James G. Herman, Kornel E. Schuebel, D. Neil Watkins, Nita Ahuja, and Stephen B. Baylin
Cancer Res 2008 68: 2764-2772. doi: 10.1158/0008-5472.CAN-07-6349 [Abstract] [Full Text] [PDF]  

MicroRNAs 221 and 222 Bypass Quiescence and Compromise Cell Survival

Ricardo Medina, Sayyed K. Zaidi, Chang-Gong Liu, Janet L. Stein, Andre J. vanWijnen, Carlo M. Croce, and Gary S. Stein
Cancer Res 2008 68: 2773-2780. doi: 10.1158/0008-5472.CAN-07-6754 [Abstract] [Full Text] [PDF] Supplementary Data  

Manganese Superoxide Dismutase Modulates Hypoxia-Inducible Factor-1 Induction via Superoxide

Suwimol Kaewpila, Sujatha Venkataraman, Garry R. Buettner, and Larry W. Oberley
Cancer Res 2008 68: 2781-2788. doi: 10.1158/0008-5472.CAN-07-2635 [Abstract] [Full Text] [PDF]  

Negative Regulation of YAP by LATS1 Underscores Evolutionary Conservation of the Drosophila Hippo Pathway

Jianmin Zhang, Gromoslaw A. Smolen, and Daniel A. Haber
Cancer Res 2008 68: 2789-2794. doi: 10.1158/0008-5472.CAN-07-6205 [Abstract] [Full Text] [PDF] Supplementary Data  

Down-regulation of Caspase-2 by Rottlerin via Protein Kinase C-–Independent Pathway

Alakananda Basu, Brett Adkins, and Chandreyi Basu
Cancer Res 2008 68: 2795-2802. doi: 10.1158/0008-5472.CAN-07-6244 [Abstract] [Full Text] [PDF]  

Targeting CD24 for Treatment of Colorectal and Pancreatic Cancer by Monoclonal Antibodies or Small Interfering RNA

Eyal Sagiv, Alex Starr, Uri Rozovski, Rami Khosravi, Peter Altevogt, Timothy Wang, and Nadir Arber
Cancer Res 2008 68: 2803-2812. doi: 10.1158/0008-5472.CAN-07-6463 [Abstract] [Full Text] [PDF]  

The Mitochondrial Uncoupling Protein-2 Promotes Chemoresistance in Cancer Cells

Zoltan Derdak, Nicholas M. Mark, Guido Beldi, Simon C. Robson, Jack R. Wands, and György Baffy
Cancer Res 2008 68: 2813-2819. doi: 10.1158/0008-5472.CAN-08-0053 [Abstract] [Full Text] [PDF]  

Experimental Therapeutics, Molecular Targets, and Chemical Biology:

Targeting Endoplasmic Reticulum Stress and Akt with OSU-03012 and Gefitinib or Erlotinib to Overcome Resistance to Epidermal Growth Factor Receptor Inhibitors

Yu-Chieh Wang, Samuel K. Kulp, Dasheng Wang, Chih-Cheng Yang, Aaron M. Sargeant, Jui-Hsiang Hung, Yoko Kashida, Mamoru Yamaguchi, Geen-Dong Chang, and Ching-Shih Chen
Cancer Res 2008 68: 2820-2830. doi: 10.1158/0008-5472.CAN-07-1336 [Abstract] [Full Text] [PDF] Supplementary Data  

Synthetic Lethality by Lentiviral Short Hairpin RNA Silencing of Thymidylate Kinase and Doxorubicin in Colon Cancer Cells Regardless of the p53 Status

Chun-Mei Hu and Zee-Fen Chang
Cancer Res 2008 68: 2831-2840. doi: 10.1158/0008-5472.CAN-07-3069 [Abstract] [Full Text] [PDF]  

Coordinated Epidermal Growth Factor Receptor Pathway Gene Overexpression Predicts Epidermal Growth Factor Receptor Inhibitor Sensitivity in Pancreatic Cancer

Antonio Jimeno, Aik Choon Tan, Jordy Coffa, N.V. Rajeshkumar, Peter Kulesza, Belen Rubio-Viqueira, Jenna Wheelhouse, Begoña Diosdado, Wells A. Messersmith, Christine Iacobuzio-Donahue, Anirban Maitra, Marileila Varella-Garcia, Fred R. Hirsch, Gerrit A. Meijer, and Manuel Hidalgo
Cancer Res 2008 68: 2841-2849. doi: 10.1158/0008-5472.CAN-07-5200 [Abstract] [Full Text] [PDF] Supplementary Data  

NVP-AUY922: A Novel Heat Shock Protein 90 Inhibitor Active against Xenograft Tumor Growth, Angiogenesis, and Metastasis

Suzanne A. Eccles, Andy Massey, Florence I. Raynaud, Swee Y. Sharp, Gary Box, Melanie Valenti, Lisa Patterson, Alexis de Haven Brandon, Sharon Gowan, Frances Boxall, Wynne Aherne, Martin Rowlands, Angela Hayes, Vanessa Martins, Frederique Urban, Kathy Boxall, Chrisostomos Prodromou, Laurence Pearl, Karen James, Thomas P. Matthews, Kwai-Ming Cheung, Andrew Kalusa, Keith Jones, Edward McDonald, Xavier Barril, Paul A. Brough, Julie E. Cansfield, Brian Dymock, Martin J. Drysdale, Harry Finch, Rob Howes, Roderick E. Hubbard, Alan Surgenor, Paul Webb, Mike Wood, Lisa Wright, and Paul Workman
Cancer Res 2008 68: 2850-2860. doi: 10.1158/0008-5472.CAN-07-5256 [Abstract] [Full Text] [PDF] Supplementary Data  

Bone Marrow X Kinase–Mediated Signal Transduction in Irradiated Vascular Endothelium

Tianxiang Tu, Dinesh Thotala, Ling Geng, Dennis E. Hallahan, and Christopher D. Willey
Cancer Res 2008 68: 2861-2869. doi: 10.1158/0008-5472.CAN-07-5743 [Abstract] [Full Text] [PDF]  

NOV-002, a Glutathione Disulfide Mimetic, as a Modulator of Cellular Redox Balance

Danyelle M. Townsend, Lin He, Steven Hutchens, Tracy E. Garrett, Christopher J. Pazoles, and Kenneth D. Tew
Cancer Res 2008 68: 2870-2877. doi: 10.1158/0008-5472.CAN-07-5957 [Abstract] [Full Text] [PDF]  

Imaging Transgene Activity In vivo

Terence P.F. Gade, Jason A. Koutcher, William M. Spees, Bradley J. Beattie, Vladimir Ponomarev, Michael Doubrovin, Ian M. Buchanan, Tatiana Beresten, Kristen L. Zakian, H. Carl Le, William P. Tong, Philipp Mayer-Kuckuk, Ronald G. Blasberg, and Juri G. Gelovani
Cancer Res 2008 68: 2878-2884. doi: 10.1158/0008-5472.CAN-07-6028 [Abstract] [Full Text] [PDF] Supplementary Data  

Targeting a Tumor-Specific Laminin Domain Critical for Human Carcinogenesis

Mark Tran, Patricia Rousselle, Pasi Nokelainen, Sruthi Tallapragada, Ngon T. Nguyen, Edgar F. Fincher, and M. Peter Marinkovich
Cancer Res 2008 68: 2885-2894. doi: 10.1158/0008-5472.CAN-07-6160 [Abstract] [Full Text] [PDF]  

Soft Tissue Sarcoma Cells Are Highly Sensitive to AKT Blockade: A Role for p53-Independent Up-regulation of GADD45

Quan-Sheng Zhu, Wenhong Ren, Borys Korchin, Guy Lahat, Adam Dicker, Yiling Lu, Gordon Mills, Raphael E. Pollock, and Dina Lev
Cancer Res 2008 68: 2895-2903. doi: 10.1158/0008-5472.CAN-07-6268 [Abstract] [Full Text] [PDF]  

New Derivatives of Vitamin B12 Show Preferential Targeting of Tumors

Robert Waibel, Hansjörg Treichler, Niklaus G. Schaefer, Dave R. van Staveren, Stefan Mundwiler, Susanne Kunze, Martin Küenzi, Roger Alberto, Jakob Nüesch, Alexander Knuth, Holger Moch, Roger Schibli, and Pius August Schubiger
Cancer Res 2008 68: 2904-2911. doi: 10.1158/0008-5472.CAN-07-6771 [Abstract] [Full Text] [PDF] Supplementary Data  

Peroxisome Proliferator-Activated Receptor –Mediated Up-regulation of Syndecan-1 by n-3 Fatty Acids Promotes Apoptosis of Human Breast Cancer Cells

Haiguo Sun, Isabelle M. Berquin, Rick T. Owens, Joseph T. O'Flaherty, and Iris J. Edwards
Cancer Res 2008 68: 2912-2919. doi: 10.1158/0008-5472.CAN-07-2305 [Abstract] [Full Text] [PDF]  

Triterpenoid CDDO-Methyl Ester Inhibits the Janus-Activated Kinase-1 (JAK1)Signal Transducer and Activator of Transcription-3 (STAT3) Pathway by Direct Inhibition of JAK1 and STAT3

Rehan Ahmad, Deepak Raina, Colin Meyer, and Donald Kufe
Cancer Res 2008 68: 2920-2926. doi: 10.1158/0008-5472.CAN-07-3036 [Abstract] [Full Text] [PDF]  

Apoptotic Activity and Mechanism of 2-Cyano-3,12-Dioxoolean-1,9-Dien-28-Oic-Acid and Related Synthetic Triterpenoids in Prostate Cancer

Marc L. Hyer, Ranxin Shi, Maryla Krajewska, Colin Meyer, Irina V. Lebedeva, Paul B. Fisher, and John C. Reed
Cancer Res 2008 68: 2927-2933. doi: 10.1158/0008-5472.CAN-07-5759 [Abstract] [Full Text] [PDF] Supplementary Data  

A New Pharmacologic Action of CCI-779 Involves FKBP12-Independent Inhibition of mTOR Kinase Activity and Profound Repression of Global Protein Synthesis

Boris Shor, Wei-Guo Zhang, Lourdes Toral-Barza, Jessica Lucas, Robert T. Abraham, James J. Gibbons, and Ker Yu
Cancer Res 2008 68: 2934-2943. doi: 10.1158/0008-5472.CAN-07-6487 [Abstract] [Full Text] [PDF] Supplementary Data  

BH3 Mimetic ABT-737 Potentiates TRAIL-Mediated Apoptotic Signaling by Unsequestering Bim and Bak in Human Pancreatic Cancer Cells

Shengbing Huang and Frank A. Sinicrope
Cancer Res 2008 68: 2944-2951. doi: 10.1158/0008-5472.CAN-07-2508 [Abstract] [Full Text] [PDF] Supplementary Data  

Immunology:

Containment of Tumor-Colonizing Bacteria by Host Neutrophils

Kathrin Westphal, Sara Leschner, Jadwiga Jablonska, Holger Loessner, and Siegfried Weiss
Cancer Res 2008 68: 2952-2960. doi: 10.1158/0008-5472.CAN-07-2984 [Abstract] [Full Text] [PDF] Supplementary Data  

Redirecting Specificity of T-Cell Populations For CD19 Using the Sleeping Beauty System

Harjeet Singh, Pallavi R. Manuri, Simon Olivares, Navid Dara, Margaret J. Dawson, Helen Huls, Perry B. Hackett, Donald B. Kohn, Elizabeth J. Shpall, Richard E. Champlin, and Laurence J.N. Cooper
Cancer Res 2008 68: 2961-2971. doi: 10.1158/0008-5472.CAN-07-5600 [Abstract] [Full Text] [PDF]  

Interleukin-15/Interleukin-15R Complexes Promote Destruction of Established Tumors by Reviving Tumor-Resident CD8⁺ T Cells

Mathieu Epardaud, Kutlu G. Elpek, Mark P. Rubinstein, Ai-ris Yonekura, Angelique Bellemare-Pelletier, Roderick Bronson, Jessica A. Hamerman, Ananda W. Goldrath, and Shannon J. Turley
Cancer Res 2008 68: 2972-2983. doi: 10.1158/0008-5472.CAN-08-0045 [Abstract] [Full Text] [PDF] Supplementary Data  

Modeling the CD8⁺ T Effector to Memory Transition in Adoptive T-Cell Antitumor Immunotherapy

Cleo E. Rolle, Roberto Carrio, and Thomas R. Malek
Cancer Res 2008 68: 2984-2992. doi: 10.1158/0008-5472.CAN-07-3040 [Abstract] [Full Text] [PDF]  

Loss of CTL Function among High-Avidity Tumor-Specific CD8⁺ T Cells following Tumor Infiltration

Claire N. Janicki, S. Rhiannon Jenkinson, Neil A. Williams, and David J. Morgan
Cancer Res 2008 68: 2993-3000. doi: 10.1158/0008-5472.CAN-07-5008 [Abstract] [Full Text] [PDF]  

The Regulatory T Cell–Associated Transcription Factor FoxP3 Is Expressed by Tumor Cells

Lisa M. Ebert, Bee Shin Tan, Judy Browning, Suzanne Svobodova, Sarah E. Russell, Naomi Kirkpatrick, Craig Gedye, Denis Moss, Sweet Ping Ng, Duncan MacGregor, Ian D. Davis, Jonathan Cebon, and Weisan Chen
Cancer Res 2008 68: 3001-3009. doi: 10.1158/0008-5472.CAN-07-5664 [Abstract] [Full Text] [PDF] Supplementary Data  

Synthetic CD4⁺ T Cell–Targeted Antigen-Presenting Cells Elicit Protective Antitumor Responses

Stefano Caserta, Patrizia Alessi, Jlenia Guarnerio, Veronica Basso, and Anna Mondino
Cancer Res 2008 68: 3010-3018. doi: 10.1158/0008-5472.CAN-07-5796 [Abstract] [Full Text] [PDF]  

Interleukin 21 Enhances Antibody-Mediated Tumor Rejection

Mark J. Smyth, Michele W.L. Teng, Janelle Sharkey, Jennifer A. Westwood, Nicole M. Haynes, Hideo Yagita, Kazuyoshi Takeda, Pallavur V. Sivakumar, and Michael H. Kershaw
Cancer Res 2008 68: 3019-3025. doi: 10.1158/0008-5472.CAN-07-6019 [Abstract] [Full Text] [PDF] Supplementary Data  

Endocrinology:

The Helix-Loop-Helix Protein Id1 Requires Cyclin D1 to Promote the Proliferation of Mammary Epithelial Cell Acini

C. Elizabeth Caldon, Alexander Swarbrick, Christine S.L. Lee, Robert L. Sutherland, and Elizabeth A. Musgrove
Cancer Res 2008 68: 3026-3036. doi: 10.1158/0008-5472.CAN-07-3079 [Abstract] [Full Text] [PDF] Supplementary Data  

Clinical Research:

Gender-Related Survival Differences Associated with EGFR Polymorphisms in Metastatic Colon Cancer

Oliver A. Press, Wu Zhang, Michael A. Gordon, Dongyun Yang, Georg Lurje, Syma Iqbal, Anthony El-Khoueiry, and Heinz-Josef Lenz
Cancer Res 2008 68: 3037-3042. doi: 10.1158/0008-5472.CAN-07-2718 [Abstract] [Full Text] [PDF]  

Epidemiology:

Genetic Variation in the Inhibin Pathway and Risk of Testicular Germ Cell Tumors

Mark P. Purdue, Barry I. Graubard, Stephen J. Chanock, Mark V. Rubertone, Ralph L. Erickson, and Katherine A. McGlynn
Cancer Res 2008 68: 3043-3048. doi: 10.1158/0008-5472.CAN-07-5852 [Abstract] [Full Text] [PDF] Supplementary Data  

Double-Strand Break Damage and Associated DNA Repair Genes Predispose Smokers to Gene Methylation

Shuguang Leng, Christine A. Stidley, Randy Willink, Amanda Bernauer, Kieu Do, Maria A. Picchi, Xin Sheng, Melissa A. Frasco, David Van Den Berg, Frank D. Gilliland, Christopher Zima, Richard E. Crowell, and Steven A. Belinsky
Cancer Res 2008 68: 3049-3056. doi: 10.1158/0008-5472.CAN-07-6344 [Abstract] [Full Text] [PDF]  

Prevention:

Enhancement of UVB-Induced Apoptosis by Apigenin in Human Keratinocytes and Organotypic Keratinocyte Cultures

Adnan O. Abu-Yousif, Kimberly A. Smith, Spiro Getsios, Kathleen J. Green, Rukiyah T. Van Dross, and Jill C. Pelling
Cancer Res 2008 68: 3057-3065. doi: 10.1158/0008-5472.CAN-07-2763 [Abstract] [Full Text] [PDF]  

Effect of Low-Fat Diet on Development of Prostate Cancer and Akt Phosphorylation in the Hi-Myc Transgenic Mouse Model

Naoko Kobayashi, R. James Barnard, Jonathan Said, Jenny Hong-Gonzalez, Dan M. Corman, Melvin Ku, Ngan Bao Doan, Dorina Gui, David Elashoff, Pinchas Cohen, and William J. Aronson
Cancer Res 2008 68: 3066-3073. doi: 10.1158/0008-5472.CAN-07-5616 [Abstract] [Full Text] [PDF] Supplementary Data  

Letters to the Editor:

A Statistical Reappraisal of the Findings of an Esophageal Cancer Genome-Wide Association Study

Alexander Statnikov, Chun Li, and Constantin F. Aliferis
Cancer Res 2008 68: 3074-3075. doi: 10.1158/0008-5472.CAN-07-2999 [Full Text] [PDF]  

Howard H. Yang, Ying Hu, Maxwell P. Lee, Nan Hu, David Ng, Alisa M. Goldstein, Chaoyu Wang, and Philip R. Taylor
Cancer Res 2008 68: 3075. doi: 10.1158/0008-5472.CAN-07-6426 [Full Text] [PDF]  

Corrections:

Correction: T-cadherin Regulates Angiogenesis

Cancer Res 2008 68: 3076. doi: 10.1158/0008-5472.CAN-68-8-COR1 [Full Text] [PDF]  

Correction: Cosmc Mutation in Cancer

Cancer Res 2008 68: 3076. doi: 10.1158/0008-5472.CAN-68-8-COR2 [Full Text] [PDF]  

Correction: Human Topoisomerase 2 Conjugates with SUMO-2

Cancer Res 2008 68: 3076. doi: 10.1158/0008-5472.CAN-68-8-COR3 [Full Text] [PDF]  

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