Reviews:

Mdm2 Affects Genome Stability Independent of p53

Alyssa Bouska and Christine M. Eischen
Cancer Res 2009 69: 1697-1701. Published Online First February 24, 2009. doi: 10.1158/0008-5472.CAN-08-3732 [Abstract] [Full Text] [PDF]  

The Critical Role of the Class III Histone Deacetylase SIRT1 in Cancer

Tao Liu, Pei Y. Liu, and Glenn M. Marshall
Cancer Res 2009 69: 1702-1705. Published Online First February 24, 2009. doi: 10.1158/0008-5472.CAN-08-3365 [Abstract] [Full Text] [PDF] Supplementary Data  

Priority Reports:

Silencing of TMS1/ASC Promotes Resistance to Anoikis in Breast Epithelial Cells

Melissa J. Parsons, Pritty Patel, Daniel J. Brat, Laronna Colbert, and Paula M. Vertino
Cancer Res 2009 69: 1706-1711. Published Online First February 17, 2009. doi: 10.1158/0008-5472.CAN-08-2351 [Abstract] [Full Text] [PDF]  

Introducing Nanochemoprevention as a Novel Approach for Cancer Control: Proof of Principle with Green Tea Polyphenol Epigallocatechin-3-Gallate

Imtiaz A. Siddiqui, Vaqar M. Adhami, Dhruba J. Bharali, Bilal B. Hafeez, Mohammad Asim, Sabih I. Khwaja, Nihal Ahmad, Huadong Cui, Shaker A. Mousa, and Hasan Mukhtar
Cancer Res 2009 69: 1712-1716. Published Online First February 17, 2009. doi: 10.1158/0008-5472.CAN-08-3978 [Abstract] [Full Text] [PDF] Supplementary Data  

Neuronal Guidance Protein Netrin-1 Induces Differentiation in Human Embryonal Carcinoma Cells

Mario Mancino, Claudia Esposito, Kazuhide Watanabe, Tadahiro Nagaoka, Monica Gonzales, Caterina Bianco, Nicola Normanno, David S. Salomon, and Luigi Strizzi
Cancer Res 2009 69: 1717-1721. Published Online First February 17, 2009. doi: 10.1158/0008-5472.CAN-08-2985 [Abstract] [Full Text] [PDF]  

The Tamoxifen Metabolite, Endoxifen, Is a Potent Antiestrogen that Targets Estrogen Receptor for Degradation in Breast Cancer Cells

Xianglin Wu, John R. Hawse, Malayannan Subramaniam, Matthew P. Goetz, James N. Ingle, and Thomas C. Spelsberg
Cancer Res 2009 69: 1722-1727. Published Online First February 24, 2009. doi: 10.1158/0008-5472.CAN-08-3933 [Abstract] [Full Text] [PDF]  

Oral Cancer Diagnosis by Mechanical Phenotyping

Torsten W. Remmerbach, Falk Wottawah, Julia Dietrich, Bryan Lincoln, Christian Wittekind, and Jochen Guck
Cancer Res 2009 69: 1728-1732. Published Online First February 17, 2009. doi: 10.1158/0008-5472.CAN-08-4073 [Abstract] [Full Text] [PDF] Supplementary Data  

Depletion of Cytosolic Phospholipase A₂ in Bone Marrow–Derived Macrophages Protects against Lung Cancer Progression and Metastasis

Mary C.M. Weiser-Evans, Xue-Qing Wang, Jay Amin, Vicki Van Putten, Rashmi Choudhary, Robert A. Winn, Robert Scheinman, Peter Simpson, Mark W. Geraci, and Raphael A. Nemenoff
Cancer Res 2009 69: 1733-1738. Published Online First February 10, 2009. doi: 10.1158/0008-5472.CAN-08-3766 [Abstract] [Full Text] [PDF]  

Cell, Tumor, and Stem Cell Biology:

Conserved Gene Expression Programs Integrate Mammalian Prostate Development and Tumorigenesis

Colin Pritchard, Brig Mecham, Ruth Dumpit, Ilsa Coleman, Madhuchhanda Bhattacharjee, Qian Chen, Robert A. Sikes, and Peter S. Nelson
Cancer Res 2009 69: 1739-1747. Published Online First February 17, 2009. doi: 10.1158/0008-5472.CAN-07-6817 [Abstract] [Full Text] [PDF] Supplementary Data  

RASSF1A Mediates p21^Cip1/Waf1-Dependent Cell Cycle Arrest and Senescence through Modulation of the Raf-MEK-ERK Pathway and Inhibition of Akt

Sonja Thaler, Patricia S. Hähnel, Arno Schad, Reinhard Dammann, and Martin Schuler
Cancer Res 2009 69: 1748-1757. Published Online First February 17, 2009. doi: 10.1158/0008-5472.CAN-08-1377 [Abstract] [Full Text] [PDF] Supplementary Data  

Structure-Function Approach Identifies a COOH-Terminal Domain That Mediates Heparanase Signaling

Liat Fux, Nir Feibish, Victoria Cohen-Kaplan, Svetlana Gingis-Velitski, Sari Feld, Chen Geffen, Israel Vlodavsky, and Neta Ilan
Cancer Res 2009 69: 1758-1767. Published Online First February 24, 2009. doi: 10.1158/0008-5472.CAN-08-1837 [Abstract] [Full Text] [PDF] Supplementary Data  

Inactivation of the Nijmegen Breakage Syndrome Gene Leads to Excess Centrosome Duplication via the ATR/BRCA1 Pathway

Mikio Shimada, Ruri Sagae, Junya Kobayashi, Toshiyuki Habu, and Kenshi Komatsu
Cancer Res 2009 69: 1768-1775. Published Online First February 24, 2009. doi: 10.1158/0008-5472.CAN-08-3016 [Abstract] [Full Text] [PDF] Supplementary Data  

Identification of Cancer Stem Cells in Ewing's Sarcoma

Mario-Luca Suvà, Nicolò Riggi, Jean-Christophe Stehle, Karine Baumer, Stéphane Tercier, Jean-Marc Joseph, Domizio Suvà, Virginie Clément, Paolo Provero, Luisa Cironi, Maria-Chiara Osterheld, Louis Guillou, and Ivan Stamenkovic
Cancer Res 2009 69: 1776-1781. Published Online First February 10, 2009. doi: 10.1158/0008-5472.CAN-08-2242 [Abstract] [Full Text] [PDF] Supplementary Data  

cIAP1, cIAP2, and XIAP Act Cooperatively via Nonredundant Pathways to Regulate Genotoxic Stress–Induced Nuclear Factor-B Activation

Hyung-Seung Jin, Dong-Hee Lee, Dong-Hwan Kim, Ji-Hye Chung, Seul-Ji Lee, and Tae H. Lee
Cancer Res 2009 69: 1782-1791. Published Online First February 17, 2009. doi: 10.1158/0008-5472.CAN-08-2256 [Abstract] [Full Text] [PDF] Supplementary Data  

Overexpression of the Cellular DEK Protein Promotes Epithelial Transformation In vitro and In vivo

Trisha M. Wise-Draper, Rachael A. Mintz-Cole, Teresa A. Morris, David S. Simpson, Kathryn A. Wikenheiser-Brokamp, Mark A. Currier, Timothy P. Cripe, Gerard C. Grosveld, and Susanne I. Wells
Cancer Res 2009 69: 1792-1799. Published Online First February 17, 2009. doi: 10.1158/0008-5472.CAN-08-2304 [Abstract] [Full Text] [PDF] Supplementary Data  

E2F7 Can Regulate Proliferation, Differentiation, and Apoptotic Responses in Human Keratinocytes: Implications for Cutaneous Squamous Cell Carcinoma Formation

Liliana Endo-Munoz, Alison Dahler, Ngari Teakle, Danny Rickwood, Mehlika Hazar-Rethinam, Ibtissam Abdul-Jabbar, Scott Sommerville, Ian Dickinson, Pritinder Kaur, Sophie Paquet-Fifield, and Nicholas Saunders
Cancer Res 2009 69: 1800-1808. Published Online First February 17, 2009. doi: 10.1158/0008-5472.CAN-08-2725 [Abstract] [Full Text] [PDF] Supplementary Data  

DDB1-CUL4 and MLL1 Mediate Oncogene-Induced p16^INK4a Activation

Yojiro Kotake, Yaxue Zeng, and Yue Xiong
Cancer Res 2009 69: 1809-1814. Published Online First February 10, 2009. doi: 10.1158/0008-5472.CAN-08-2739 [Abstract] [Full Text] [PDF]  

Rat Umbilical Cord Stem Cells Completely Abolish Rat Mammary Carcinomas with No Evidence of Metastasis or Recurrence 100 Days Post–Tumor Cell Inoculation

Chanran Ganta, Doi Chiyo, Rie Ayuzawa, Rajashekar Rachakatla, Marla Pyle, Gordon Andrews, Mark Weiss, Masaaki Tamura, and Deryl Troyer
Cancer Res 2009 69: 1815-1820. Published Online First February 24, 2009. doi: 10.1158/0008-5472.CAN-08-2750 [Abstract] [Full Text] [PDF] Supplementary Data  

TORC-Specific Phosphorylation of Mammalian Target of Rapamycin (mTOR): Phospho-Ser²⁴⁸¹ Is a Marker for Intact mTOR Signaling Complex 2

Jeremy Copp, Gerard Manning, and Tony Hunter
Cancer Res 2009 69: 1821-1827. Published Online First February 24, 2009. doi: 10.1158/0008-5472.CAN-08-3014 [Abstract] [Full Text] [PDF] Supplementary Data  

Hepatocyte Growth Factor Activator Inhibitor Type 1 Regulates Epithelial to Mesenchymal Transition through Membrane-Bound Serine Proteinases

Haixia Cheng, Tsuyoshi Fukushima, Nobuyasu Takahashi, Hiroyuki Tanaka, and Hiroaki Kataoka
Cancer Res 2009 69: 1828-1835. Published Online First February 17, 2009. doi: 10.1158/0008-5472.CAN-08-3728 [Abstract] [Full Text] [PDF] Supplementary Data  

Control of HIF-1 Expression by eIF2 Phosphorylation–Mediated Translational Repression

Keyi Zhu, WaiKin Chan, John Heymach, Miles Wilkinson, and David J. McConkey
Cancer Res 2009 69: 1836-1843. Published Online First February 24, 2009. doi: 10.1158/0008-5472.CAN-08-4103 [Abstract] [Full Text] [PDF] Supplementary Data  

HMGA Proteins Up-regulate CCNB2 Gene in Mouse and Human Pituitary Adenomas

Ivana De Martino, Rosa Visone, Anne Wierinckx, Dario Palmieri, Angelo Ferraro, Paolo Cappabianca, Gennaro Chiappetta, Floriana Forzati, Gaetano Lombardi, Annamaria Colao, Jacqueline Trouillas, Monica Fedele, and Alfredo Fusco
Cancer Res 2009 69: 1844-1850. Published Online First February 17, 2009. doi: 10.1158/0008-5472.CAN-08-4133 [Abstract] [Full Text] [PDF]  

Clinical Research:

PIK3CA Mutations in Colorectal Cancer Are Associated with Clinical Resistance to EGFR-Targeted Monoclonal Antibodies

Andrea Sartore-Bianchi, Miriam Martini, Francesca Molinari, Silvio Veronese, Michele Nichelatti, Salvatore Artale, Federica Di Nicolantonio, Piercarlo Saletti, Sara De Dosso, Luca Mazzucchelli, Milo Frattini, Salvatore Siena, and Alberto Bardelli
Cancer Res 2009 69: 1851-1857. Published Online First February 17, 2009. doi: 10.1158/0008-5472.CAN-08-2466 [Abstract] [Full Text] [PDF] Supplementary Data  

Endocrinology:

Recapitulation of Pancreatic Neuroendocrine Tumors in Human Multiple Endocrine Neoplasia Type I Syndrome via Pdx1-Directed Inactivation of Men1

H.-C. Jennifer Shen, Mei He, Anathea Powell, Asha Adem, Dominique Lorang, Charles Heller, Amelia C. Grover, Kris Ylaya, Stephen M. Hewitt, Stephen J. Marx, Allen M. Spiegel, and Steven K. Libutti
Cancer Res 2009 69: 1858-1866. Published Online First February 10, 2009. doi: 10.1158/0008-5472.CAN-08-3662 [Abstract] [Full Text] [PDF] Supplementary Data  

The β-Catenin Axis Integrates Multiple Signals Downstream from RET/Papillary Thyroid Carcinoma Leading to Cell Proliferation

Maria Domenica Castellone, Valentina De Falco, Deva Magendra Rao, Roberto Bellelli, Magesh Muthu, Fulvio Basolo, Alfredo Fusco, J. Silvio Gutkind, and Massimo Santoro
Cancer Res 2009 69: 1867-1876. Published Online First February 17, 2009. doi: 10.1158/0008-5472.CAN-08-1982 [Abstract] [Full Text] [PDF]  

Epidemiology:

Xenobiotic Metabolizing Gene Variants, Dietary Heterocyclic Amine Intake, and Risk of Prostate Cancer

Stella Koutros, Sonja I. Berndt, Rashmi Sinha, Xiaomei Ma, Nilanjan Chatterjee, Michael C.R. Alavanja, Tongzhang Zheng, Wen-Yi Huang, Richard B. Hayes, and Amanda J. Cross
Cancer Res 2009 69: 1877-1884. Published Online First February 17, 2009. doi: 10.1158/0008-5472.CAN-08-2447 [Abstract] [Full Text] [PDF] Supplementary Data  

Polymorphisms in the Vitamin D Receptor and Risk of Ovarian Cancer in Four Studies

Shelley S. Tworoger, Margaret A. Gate, I-Min Lee, Julie E. Buring, Linda Titus-Ernstoff, Daniel Cramer, and Susan E. Hankinson
Cancer Res 2009 69: 1885-1891. Published Online First February 17, 2009. doi: 10.1158/0008-5472.CAN-08-3515 [Abstract] [Full Text] [PDF]  

Functional Significance of UDP-Glucuronosyltransferase Variants in the Metabolism of Active Tamoxifen Metabolites

Andrea S. Blevins-Primeau, Dongxiao Sun, Gang Chen, Arun K. Sharma, Carla J. Gallagher, Shantu Amin, and Philip Lazarus
Cancer Res 2009 69: 1892-1900. Published Online First February 24, 2009. doi: 10.1158/0008-5472.CAN-08-3708 [Abstract] [Full Text] [PDF]  

Polychlorinated Biphenyls and Risk of Testicular Germ Cell Tumors

Katherine A. McGlynn, Sabah M. Quraishi, Barry I. Graubard, Jean-Philippe Weber, Mark V. Rubertone, and Ralph L. Erickson
Cancer Res 2009 69: 1901-1909. Published Online First February 17, 2009. doi: 10.1158/0008-5472.CAN-08-3935 [Abstract] [Full Text] [PDF] Supplementary Data  

Experimental Therapeutics, Molecular Targets, and Chemical Biology:

Novel Microtubule Polymerization Inhibitor with Potent Antiproliferative and Antitumor Activity

Sonia Arora, Xin I. Wang, Susan M. Keenan, Christina Andaya, Qiang Zhang, Youyi Peng, and William J. Welsh
Cancer Res 2009 69: 1910-1915. Published Online First February 17, 2009. doi: 10.1158/0008-5472.CAN-08-0877 [Abstract] [Full Text] [PDF]  

Identification of Polo-like Kinase 1 as a Potential Therapeutic Target in Anaplastic Thyroid Carcinoma

Tito Claudio Nappi, Paolo Salerno, Horst Zitzelsberger, Francesca Carlomagno, Giuliana Salvatore, and Massimo Santoro
Cancer Res 2009 69: 1916-1923. Published Online First February 17, 2009. doi: 10.1158/0008-5472.CAN-08-1693 [Abstract] [Full Text] [PDF] Supplementary Data  

Characterization of a Novel Mitogen-Activated Protein Kinase Kinase 1/2 Inhibitor with a Unique Mechanism of Action for Cancer Therapy

Sherif Daouti, Huisheng Wang, Wen-hui Li, Brian Higgins, Kenneth Kolinsky, Kathryn Packman, Anthony Specian, Jr., Norman Kong, Nicholas Huby, Yang Wen, Qing Xiang, Frank J. Podlaski, Yang He, Nader Fotouhi, David Heimbrook, and Huifeng Niu
Cancer Res 2009 69: 1924-1932. Published Online First February 24, 2009. doi: 10.1158/0008-5472.CAN-08-2627 [Abstract] [Full Text] [PDF] Supplementary Data  

Design and Activity of a Murine and Humanized Anti-CEACAM6 Single-Chain Variable Fragment in the Treatment of Pancreatic Cancer

Christopher J. Riley, Kevin P. Engelhardt, Jose W. Saldanha, Wenqing Qi, Laurence S. Cooke, Yingting Zhu, Satya T. Narayan, Kishore Shakalya, Kimiko Della Croce, Ivan G. Georgiev, Raymond B. Nagle, Harinder Garewal, Daniel D. Von Hoff, and Daruka Mahadevan
Cancer Res 2009 69: 1933-1940. Published Online First February 24, 2009. doi: 10.1158/0008-5472.CAN-08-2707 [Abstract] [Full Text] [PDF]  

LY303511 Enhances TRAIL Sensitivity of SHEP-1 Neuroblastoma Cells via Hydrogen Peroxide–Mediated Mitogen-Activated Protein Kinase Activation and Up-regulation of Death Receptors

Kirthan Shenoy, Yongfei Wu, and Shazib Pervaiz
Cancer Res 2009 69: 1941-1950. Published Online First February 17, 2009. doi: 10.1158/0008-5472.CAN-08-1996 [Abstract] [Full Text] [PDF] Supplementary Data  

Chemoresistant Colorectal Cancer Cells, the Cancer Stem Cell Phenotype, and Increased Sensitivity to Insulin-like Growth Factor-I Receptor Inhibition

Nikolaos A. Dallas, Ling Xia, Fan Fan, Michael J. Gray, Puja Gaur, George van Buren, II, Shaija Samuel, Michael P. Kim, Sherry J. Lim, and Lee M. Ellis
Cancer Res 2009 69: 1951-1957. Published Online First February 24, 2009. doi: 10.1158/0008-5472.CAN-08-2023 [Abstract] [Full Text] [PDF]  

Sustained Src Inhibition Results in Signal Transducer and Activator of Transcription 3 (STAT3) Activation and Cancer Cell Survival via Altered Janus-Activated Kinase–STAT3 Binding

Banibrata Sen, Babita Saigal, Nila Parikh, Gary Gallick, and Faye M. Johnson
Cancer Res 2009 69: 1958-1965. Published Online First February 17, 2009. doi: 10.1158/0008-5472.CAN-08-2944 [Abstract] [Full Text] [PDF]  

Acquired Resistance to 17-Allylamino-17-Demethoxygeldanamycin (17-AAG, Tanespimycin) in Glioblastoma Cells

Nathalie Gaspar, Swee Y. Sharp, Simon Pacey, Chris Jones, Michael Walton, Gilles Vassal, Suzanne Eccles, Andrew Pearson, and Paul Workman
Cancer Res 2009 69: 1966-1975. Published Online First February 24, 2009. doi: 10.1158/0008-5472.CAN-08-3131 [Abstract] [Full Text] [PDF] Supplementary Data  

Down-regulation of Vascular Endothelial Growth Factor Receptor 2 Is a Major Molecular Determinant of Proteasome Inhibitor–Mediated Antiangiogenic Action in Endothelial Cells

Markus Meissner, Gabi Reichenbach, Monika Stein, Igor Hrgovic, Roland Kaufmann, and Jens Gille
Cancer Res 2009 69: 1976-1984. Published Online First February 17, 2009. doi: 10.1158/0008-5472.CAN-08-3150 [Abstract] [Full Text] [PDF] Supplementary Data  

Mitogen-Activated Protein Kinase Inhibition Induces Translocation of Bmf to Promote Apoptosis in Melanoma

Matthew W. VanBrocklin, Monique Verhaegen, Maria S. Soengas, and Sheri L. Holmen
Cancer Res 2009 69: 1985-1994. Published Online First February 24, 2009. doi: 10.1158/0008-5472.CAN-08-3934 [Abstract] [Full Text] [PDF] Supplementary Data  

The Interleukin-11 Receptor as a Candidate Ligand-Directed Target in Osteosarcoma: Consistent Data from Cell Lines, Orthotopic Models, and Human Tumor Samples

Valerae O. Lewis, Michael G. Ozawa, Michael T. Deavers, Guiying Wang, Tomo Shintani, Wadih Arap, and Renata Pasqualini
Cancer Res 2009 69: 1995-1999. Published Online First February 24, 2009. doi: 10.1158/0008-5472.CAN-08-4845 [Abstract] [Full Text] [PDF] Supplementary Data  

Immunology:

Regulatory T Cells Recruited through CCL22/CCR4 Are Selectively Activated in Lymphoid Infiltrates Surrounding Primary Breast Tumors and Lead to an Adverse Clinical Outcome

Michael Gobert, Isabelle Treilleux, Nathalie Bendriss-Vermare, Thomas Bachelot, Sophie Goddard-Leon, Vanessa Arfi, Cathy Biota, Anne Claire Doffin, Isabelle Durand, Daniel Olive, Solène Perez, Nicolas Pasqual, Christelle Faure, Isabelle Ray-Coquard, Alain Puisieux, Christophe Caux, Jean-Yves Blay, and Christine Ménétrier-Caux
Cancer Res 2009 69: 2000-2009. Published Online First February 24, 2009. doi: 10.1158/0008-5472.CAN-08-2360 [Abstract] [Full Text] [PDF] Supplementary Data  

IFN Promotes Papilloma Development by Up-regulating Th17-Associated Inflammation

Mingjie Xiao, Chunhui Wang, Jinhua Zhang, Zhiguang Li, Xueqiang Zhao, and Zhihai Qin
Cancer Res 2009 69: 2010-2017. Published Online First February 24, 2009. doi: 10.1158/0008-5472.CAN-08-3479 [Abstract] [Full Text] [PDF]  

Enhanced Immune Recognition of Cryptic Glycan Markers in Human Tumors

Thomas E. Newsom-Davis, Denong Wang, Lawrence Steinman, Paul F-T. Chen, Lai-Xi Wang, A. Katharina Simon, and Gavin R. Screaton
Cancer Res 2009 69: 2018-2025. Published Online First February 17, 2009. doi: 10.1158/0008-5472.CAN-08-3589 [Abstract] [Full Text] [PDF] Supplementary Data  

Tumor-Induced Suppression of CTL Expansion and Subjugation by gp96-Ig Vaccination

Taylor H. Schreiber, Vadim V. Deyev, Joseph D. Rosenblatt, and Eckhard R. Podack
Cancer Res 2009 69: 2026-2033. Published Online First February 17, 2009. doi: 10.1158/0008-5472.CAN-08-3706 [Abstract] [Full Text] [PDF] Supplementary Data  

Kinetic Preservation of Dual Specificity of Coprogrammed Minor Histocompatibility Antigen-Reactive Virus-Specific T Cells

Marleen M. van Loenen, Renate S. Hagedoorn, Michel G.D. Kester, Manja Hoogeboom, Roel Willemze, J.H. Frederik Falkenburg, and Mirjam H.M. Heemskerk
Cancer Res 2009 69: 2034-2041. Published Online First February 17, 2009. doi: 10.1158/0008-5472.CAN-08-2523 [Abstract] [Full Text] [PDF]  

Molecular Biology, Pathobiology, and Genetics:

Heat-Induced Perturbations of DNA Damage Signaling Pathways are Modulated by Molecular Chaperones

Andrei Laszlo and Ilona Fleischer
Cancer Res 2009 69: 2042-2049. Published Online First February 24, 2009. doi: 10.1158/0008-5472.CAN-08-1639 [Abstract] [Full Text] [PDF] Supplementary Data  

E-Cadherin Deficiency Initiates Gastric Signet-Ring Cell Carcinoma in Mice and Man

Bostjan Humar, Vanessa Blair, Amanda Charlton, Helen More, Iain Martin, and Parry Guilford
Cancer Res 2009 69: 2050-2056. Published Online First February 17, 2009. doi: 10.1158/0008-5472.CAN-08-2457 [Abstract] [Full Text] [PDF] Supplementary Data  

Activation of Ribosomal RNA Transcription by Hepatitis C Virus Involves Upstream Binding Factor Phosphorylation via Induction of Cyclin D1

Santanu Raychaudhuri, Vanessa Fontanes, Bhaswati Barat, and Asim Dasgupta
Cancer Res 2009 69: 2057-2064. Published Online First February 17, 2009. doi: 10.1158/0008-5472.CAN-08-3468 [Abstract] [Full Text] [PDF] Supplementary Data  

Lysine-Specific Demethylase 1 Is Strongly Expressed in Poorly Differentiated Neuroblastoma: Implications for Therapy

Johannes H. Schulte, Soyoung Lim, Alexander Schramm, Nicolaus Friedrichs, Jan Koster, Rogier Versteeg, Ingrid Ora, Kristian Pajtler, Ludger Klein-Hitpass, Steffi Kuhfittig-Kulle, Eric Metzger, Roland Schüle, Angelika Eggert, Reinhard Buettner, and Jutta Kirfel
Cancer Res 2009 69: 2065-2071. Published Online First February 17, 2009. doi: 10.1158/0008-5472.CAN-08-1735 [Abstract] [Full Text] [PDF] Supplementary Data  

EphA2 Reexpression Prompts Invasion of Melanoma Cells Shifting from Mesenchymal to Amoeboid-like Motility Style

Matteo Parri, Maria Letizia Taddei, Francesca Bianchini, Lido Calorini, and Paola Chiarugi
Cancer Res 2009 69: 2072-2081. Published Online First February 24, 2009. doi: 10.1158/0008-5472.CAN-08-1845 [Abstract] [Full Text] [PDF] Supplementary Data  

Alternative Splicing of Cyr61 Is Regulated by Hypoxia and Significantly Changed in Breast Cancer

Marc Hirschfeld, Axel zur Hausen, Herta Bettendorf, Markus Jäger, and Elmar Stickeler
Cancer Res 2009 69: 2082-2090. Published Online First February 24, 2009. doi: 10.1158/0008-5472.CAN-08-1997 [Abstract] [Full Text] [PDF]  

Unsupervised Analysis of Transcriptomic Profiles Reveals Six Glioma Subtypes

Aiguo Li, Jennifer Walling, Susie Ahn, Yuri Kotliarov, Qin Su, Martha Quezado, J. Carl Oberholtzer, John Park, Jean C. Zenklusen, and Howard A. Fine
Cancer Res 2009 69: 2091-2099. Published Online First February 24, 2009. doi: 10.1158/0008-5472.CAN-08-2100 [Abstract] [Full Text] [PDF] Supplementary Data  

Telomere Dysfunction and DNA-PKcs Deficiency: Characterization and Consequence

Eli S. Williams, Rebekah Klingler, Brian Ponnaiya, Tanja Hardt, Evelin Schrock, Susan P. Lees-Miller, Katheryn Meek, Robert L. Ullrich, and Susan M. Bailey
Cancer Res 2009 69: 2100-2107. Published Online First February 24, 2009. doi: 10.1158/0008-5472.CAN-08-2854 [Abstract] [Full Text] [PDF] Supplementary Data  

RGS17, an Overexpressed Gene in Human Lung and Prostate Cancer, Induces Tumor Cell Proliferation Through the Cyclic AMP-PKA-CREB Pathway

Michael A. James, Yan Lu, Yan Liu, Haris G. Vikis, and Ming You
Cancer Res 2009 69: 2108-2116. Published Online First February 24, 2009. doi: 10.1158/0008-5472.CAN-08-3495 [Abstract] [Full Text] [PDF] Supplementary Data  

Prevention:

Sulforaphane Inhibits Prostate Carcinogenesis and Pulmonary Metastasis in TRAMP Mice in Association with Increased Cytotoxicity of Natural Killer Cells

Shivendra V. Singh, Renaud Warin, Dong Xiao, Anna A. Powolny, Silvia D. Stan, Julie A. Arlotti, Yan Zeng, Eun-Ryeong Hahm, Stanley W. Marynowski, Ajay Bommareddy, Dhimant Desai, Shantu Amin, Robert A. Parise, Jan H. Beumer, and William H. Chambers
Cancer Res 2009 69: 2117-2125. Published Online First February 17, 2009. doi: 10.1158/0008-5472.CAN-08-3502 [Abstract] [Full Text] [PDF]  

Systems Biology and Emerging Technologies:

L-Amino Acid Transporter-1 and Boronophenylalanine-Based Boron Neutron Capture Therapy of Human Brain Tumors

Allah Detta and Garth S. Cruickshank
Cancer Res 2009 69: 2126-2132. Published Online First February 24, 2009. doi: 10.1158/0008-5472.CAN-08-2345 [Abstract] [Full Text] [PDF]  

Granulocyte Macrophage Colony-Stimulating Factor Inhibits Breast Cancer Growth and Metastasis by Invoking an Anti-Angiogenic Program in Tumor-Educated Macrophages

Tim D. Eubank, Ryan D. Roberts, Mahmood Khan, Jennifer M. Curry, Gerard J. Nuovo, Periannan Kuppusamy, and Clay B. Marsh
Cancer Res 2009 69: 2133-2140. Published Online First February 17, 2009. doi: 10.1158/0008-5472.CAN-08-1405 [Abstract] [Full Text] [PDF]  

Tumor Microenvironment:

Dysfunctional Microvasculature as a Consequence of Shb Gene Inactivation Causes Impaired Tumor Growth

Nina S. Funa, Vitezslav Kriz, Guangxiang Zang, Gabriela Calounova, Björn Åkerblom, Jaroslav Mares, Erik Larsson, Ying Sun, Christer Betsholtz, and Michael Welsh
Cancer Res 2009 69: 2141-2148. Published Online First February 17, 2009. doi: 10.1158/0008-5472.CAN-08-3797 [Abstract] [Full Text] [PDF] Supplementary Data  

Corrections:

Correction: Article on Combination Therapy Using PD 0332991 and Bortezomib

Cancer Res 2009 69: 2149. Published Online First February 24, 2009. doi: 10.1158/0008-5472.CAN-69-5-COR1 [Full Text] [PDF]  

Correction: Article on Differential Sensitivity to IGF-IR Inhibitor

Cancer Res 2009 69: 2149. Published Online First February 24, 2009. doi: 10.1158/0008-5472.CAN-69-5-COR2 [Full Text] [PDF]  

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