Reviews:

Coordinates in the Universe of Node-Negative Breast Cancer Revisited

Marcus Schmidt, Jan G. Hengstler, Christian von Törne, Heinz Koelbl, and Mathias C. Gehrmann
Cancer Res 2009 69: 2695-2698. Published Online First March 24, 2009. doi: 10.1158/0008-5472.CAN-08-4013 [Abstract] [Full Text] [PDF] Supplementary Data  

Potential Stages for Prostate Cancer Prevention with Selenium: Implications for Cancer Survivors

Nicole Facompre and Karam El-Bayoumy
Cancer Res 2009 69: 2699-2703. Published Online First March 24, 2009. doi: 10.1158/0008-5472.CAN-08-4359 [Abstract] [Full Text] [PDF]  

Priority Reports:

In vivo Imaging of Cutaneous T-Cell Lymphoma Migration to the Skin

Christoph Hoeller, Stephen K. Richardson, Lai Guan Ng, Teresa Valero, Maria Wysocka, Alain H. Rook, and Wolfgang Weninger
Cancer Res 2009 69: 2704-2708. Published Online First March 24, 2009. doi: 10.1158/0008-5472.CAN-08-2891 [Abstract] [Full Text] [PDF] Supplementary Data  

Noninvasive De novo Imaging of Human Embryonic Stem Cell–Derived Teratoma Formation

Feng Cao, Zibo Li, Andrew Lee, Zhaofei Liu, Kai Chen, Hui Wang, Weibo Cai, Xiaoyuan Chen, and Joseph C. Wu
Cancer Res 2009 69: 2709-2713. Published Online First March 24, 2009. doi: 10.1158/0008-5472.CAN-08-4122 [Abstract] [Full Text] [PDF] Supplementary Data  

Real-time Study of E-Cadherin and Membrane Dynamics in Living Animals: Implications for Disease Modeling and Drug Development

Alan Serrels, Paul Timpson, Marta Canel, Juliane P. Schwarz, Neil O. Carragher, Margaret C. Frame, Valerie G. Brunton, and Kurt I. Anderson
Cancer Res 2009 69: 2714-2719. Published Online First March 24, 2009. doi: 10.1158/0008-5472.CAN-08-4308 [Abstract] [Full Text] [PDF] Supplementary Data  

A Novel Prostate Cancer Susceptibility Locus at 19q13

Fang-Chi Hsu, Jielin Sun, Fredrik Wiklund, Sarah D. Isaacs, Kathleen E. Wiley, Lina D. Purcell, Zhengrong Gao, Pär Stattin, Yi Zhu, Seong-Tae Kim, Zheng Zhang, Wennuan Liu, Bao-Li Chang, Patrick C. Walsh, David Duggan, John D. Carpten, William B. Isaacs, Henrik Grönberg, Jianfeng Xu, and S. Lilly Zheng
Cancer Res 2009 69: 2720-2723. Published Online First March 24, 2009. doi: 10.1158/0008-5472.CAN-08-3347 [Abstract] [Full Text] [PDF] Supplementary Data  

A Breast Cancer Risk Haplotype in the Caspase-8 Gene

Neil Duncan Shephard, Ryan Abo, Sushila Harkisandas Rigas, Bernd Frank, Wei-Yu Lin, Ian Wallace Brock, Adam Shippen, Sabapathy Prakash Balasubramanian, Malcolm Walter Ronald Reed, Claus Rainer Bartram, Alfons Meindl, Rita Katharina Schmutzler, Christoph Engel, Barbara Burwinkel, Lisa Anne Cannon-Albright, Kristina Allen-Brady, Nicola Jane Camp, and Angela Cox
Cancer Res 2009 69: 2724-2728. Published Online First March 24, 2009. doi: 10.1158/0008-5472.CAN-08-4266 [Abstract] [Full Text] [PDF] Supplementary Data  

Induction of Prostaglandin E₂ Pathway Promotes Gastric Hamartoma Development with Suppression of Bone Morphogenetic Protein Signaling

Hiroko Oshima, Hiraku Itadani, Hidehito Kotani, Makoto Mark Taketo, and Masanobu Oshima
Cancer Res 2009 69: 2729-2733. Published Online First March 24, 2009. doi: 10.1158/0008-5472.CAN-08-4394 [Abstract] [Full Text] [PDF] Supplementary Data  

SLC45A3-ELK4 Is a Novel and Frequent Erythroblast Transformation–Specific Fusion Transcript in Prostate Cancer

David S. Rickman, Dorothee Pflueger, Benjamin Moss, Vanessa E. VanDoren, Chen X. Chen, Alexandre de la Taille, Rainer Kuefer, Ashutosh K. Tewari, Sunita R. Setlur, Francesca Demichelis, and Mark A. Rubin
Cancer Res 2009 69: 2734-2738. Published Online First March 17, 2009. doi: 10.1158/0008-5472.CAN-08-4926 [Abstract] [Full Text] [PDF] Supplementary Data  

Cell, Tumor, and Stem Cell Biology:

Inhibition of the Sodium Potassium Adenosine Triphosphatase Pump Sensitizes Cancer Cells to Anoikis and Prevents Distant Tumor Formation

Craig D. Simpson, Imtiaz A. Mawji, Kika Anyiwe, Moyo A. Williams, Xiaoming Wang, Amudha L. Venugopal, Marcela Gronda, Rose Hurren, Sonia Cheng, Stefano Serra, Reza Beheshti Zavareh, Alessandro Datti, Jeffrey L. Wrana, Shereen Ezzat, and Aaron D. Schimmer
Cancer Res 2009 69: 2739-2747. Published Online First March 17, 2009. doi: 10.1158/0008-5472.CAN-08-2530 [Abstract] [Full Text] [PDF] Supplementary Data  

Spleen Tyrosine Kinase Functions as a Tumor Suppressor in Melanoma Cells by Inducing Senescence-like Growth Arrest

Olivier Bailet, Nina Fenouille, Patricia Abbe, Guillaume Robert, Stéphane Rocchi, Nadège Gonthier, Christophe Denoyelle, Michel Ticchioni, Jean-Paul Ortonne, Robert Ballotti, Marcel Deckert, and Sophie Tartare-Deckert
Cancer Res 2009 69: 2748-2756. Published Online First March 17, 2009. doi: 10.1158/0008-5472.CAN-08-2690 [Abstract] [Full Text] [PDF] Supplementary Data  

TW-37, a Small-Molecule Inhibitor of Bcl-2, Inhibits Cell Growth and Induces Apoptosis in Pancreatic Cancer: Involvement of Notch-1 Signaling Pathway

Zhiwei Wang, Asfar Sohail Azmi, Aamir Ahmad, Sanjeev Banerjee, Shaomeng Wang, Fazlul H. Sarkar, and Ramzi M. Mohammad
Cancer Res 2009 69: 2757-2765. Published Online First March 24, 2009. doi: 10.1158/0008-5472.CAN-08-3060 [Abstract] [Full Text] [PDF] Supplementary Data  

Activation of DNA Methyltransferase 1 by EBV Latent Membrane Protein 2A Leads to Promoter Hypermethylation of PTEN Gene in Gastric Carcinoma

Rumi Hino, Hiroshi Uozaki, Noriko Murakami, Tetsuo Ushiku, Aya Shinozaki, Shumpei Ishikawa, Teppei Morikawa, Takeo Nakaya, Takashi Sakatani, Kenzo Takada, and Masashi Fukayama
Cancer Res 2009 69: 2766-2774. Published Online First April 1, 2009. doi: 10.1158/0008-5472.CAN-08-3070 [Abstract] [Full Text] [PDF] Supplementary Data  

Central Role of c-Myc during Malignant Conversion in Human Hepatocarcinogenesis

Pal Kaposi-Novak, Louis Libbrecht, Hyun Goo Woo, Yun-Han Lee, Nathaniel C. Sears, Elizabeth A. Conner, Valentina M. Factor, Tania Roskams, and Snorri S. Thorgeirsson
Cancer Res 2009 69: 2775-2782. Published Online First March 10, 2009. doi: 10.1158/0008-5472.CAN-08-3357 [Abstract] [Full Text] [PDF] Supplementary Data  

Thyroid Transcription Factor-1 Inhibits Transforming Growth Factor-β–Mediated Epithelial-to-Mesenchymal Transition in Lung Adenocarcinoma Cells

Roy-Akira Saito, Tetsuro Watabe, Kana Horiguchi, Tadashi Kohyama, Masao Saitoh, Takahide Nagase, and Kohei Miyazono
Cancer Res 2009 69: 2783-2791. Published Online First March 17, 2009. doi: 10.1158/0008-5472.CAN-08-3490 [Abstract] [Full Text] [PDF] Supplementary Data  

Diaphanous-Related Formins Are Required for Invadopodia Formation and Invasion of Breast Tumor Cells

Floria Lizárraga, Renaud Poincloux, Maryse Romao, Guillaume Montagnac, Gaëlle Le Dez, Isabelle Bonne, Guillem Rigaill, Graça Raposo, and Philippe Chavrier
Cancer Res 2009 69: 2792-2800. Published Online First March 10, 2009. doi: 10.1158/0008-5472.CAN-08-3709 [Abstract] [Full Text] [PDF] Supplementary Data  

Endothelial Nitric Oxide Synthase Mediates Lymphangiogenesis and Lymphatic Metastasis

Johanna Lahdenranta, Jeroen Hagendoorn, Timothy P. Padera, Tohru Hoshida, Gregory Nelson, Satoshi Kashiwagi, Rakesh K. Jain, and Dai Fukumura
Cancer Res 2009 69: 2801-2808. Published Online First March 24, 2009. doi: 10.1158/0008-5472.CAN-08-4051 [Abstract] [Full Text] [PDF] Supplementary Data  

The Receptor Interacting Protein 1 Inhibits p53 Induction through NF-B Activation and Confers a Worse Prognosis in Glioblastoma

Seongmi Park, Kimmo J. Hatanpaa, Yang Xie, Bruce E. Mickey, Christopher J. Madden, Jack M. Raisanen, Deepti B. Ramnarain, Guanghua Xiao, Debabrata Saha, David A. Boothman, Dawen Zhao, Robert M. Bachoo, Russell O. Pieper, and Amyn A. Habib
Cancer Res 2009 69: 2809-2816. doi: 10.1158/0008-5472.CAN-08-4079 [Abstract] [Full Text] [PDF] Supplementary Data  

Altered Subcellular Localization of Tumor-Specific Cyclin E Isoforms Affects Cyclin-Dependent Kinase 2 Complex Formation and Proteasomal Regulation

Nikki A. Delk, Kelly K. Hunt, and Khandan Keyomarsi
Cancer Res 2009 69: 2817-2825. Published Online First March 24, 2009. doi: 10.1158/0008-5472.CAN-08-4182 [Abstract] [Full Text] [PDF] Supplementary Data  

GPR109A Is a G-protein–Coupled Receptor for the Bacterial Fermentation Product Butyrate and Functions as a Tumor Suppressor in Colon

Muthusamy Thangaraju, Gail A. Cresci, Kebin Liu, Sudha Ananth, Jaya P. Gnanaprakasam, Darren D. Browning, John D. Mellinger, Sylvia B. Smith, Gregory J. Digby, Nevin A. Lambert, Puttur D. Prasad, and Vadivel Ganapathy
Cancer Res 2009 69: 2826-2832. Published Online First March 10, 2009. doi: 10.1158/0008-5472.CAN-08-4466 [Abstract] [Full Text] [PDF] Supplementary Data  

MUC1-Induced Transcriptional Programs Associated with Tumorigenesis Predict Outcome in Breast and Lung Cancer

Nikolai N. Khodarev, Sean P. Pitroda, Michael A. Beckett, Dhara M. MacDermed, Lei Huang, Donald W. Kufe, and Ralph R. Weichselbaum
Cancer Res 2009 69: 2833-2837. Published Online First March 24, 2009. doi: 10.1158/0008-5472.CAN-08-4513 [Abstract] [Full Text] [PDF] Supplementary Data  

Rho GDP Dissociation Inhibitor 2 Suppresses Metastasis via Unconventional Regulation of RhoGTPases

Konstadinos Moissoglu, Kevin S. McRoberts, Jeremy A. Meier, Dan Theodorescu, and Martin A. Schwartz
Cancer Res 2009 69: 2838-2844. Published Online First March 10, 2009. doi: 10.1158/0008-5472.CAN-08-1397 [Abstract] [Full Text] [PDF] Supplementary Data  

The Membrane Mucin Muc4 Inhibits Apoptosis Induced by Multiple Insults via ErbB2-Dependent and ErbB2-Independent Mechanisms

Heather C. Workman, Colleen Sweeney, and Kermit L. Carraway, III
Cancer Res 2009 69: 2845-2852. Published Online First March 17, 2009. doi: 10.1158/0008-5472.CAN-08-2089 [Abstract] [Full Text] [PDF] Supplementary DataSupplementary Data  

Angiotensinogen Delays Angiogenesis and Tumor Growth of Hepatocarcinoma in Transgenic Mice

François Vincent, Philippe Bonnin, Maud Clemessy, Jean-Olivier Contrerès, Noël Lamandé, Jean-Marie Gasc, José Vilar, Patricia Hainaud, Gérard Tobelem, Pierre Corvol, and Evelyne Dupuy
Cancer Res 2009 69: 2853-2860. Published Online First March 24, 2009. doi: 10.1158/0008-5472.CAN-08-2484 [Abstract] [Full Text] [PDF] Supplementary Data  

The Human Cytomegalovirus–Encoded Chemokine Receptor US28 Promotes Angiogenesis and Tumor Formation via Cyclooxygenase-2

David Maussang, Ellen Langemeijer, Carlos P. Fitzsimons, Marijke Stigter-van Walsum, Remco Dijkman, Martin K. Borg, Erik Slinger, Andreas Schreiber, Detlef Michel, Cornelis P. Tensen, Guus A.M.S. van Dongen, Rob Leurs, and Martine J. Smit
Cancer Res 2009 69: 2861-2869. Published Online First March 24, 2009. doi: 10.1158/0008-5472.CAN-08-2487 [Abstract] [Full Text] [PDF] Supplementary Data  

PME-1 Protects Extracellular Signal-Regulated Kinase Pathway Activity from Protein Phosphatase 2A–Mediated Inactivation in Human Malignant Glioma

Pietri Puustinen, Melissa R. Junttila, Sari Vanhatupa, Anna A. Sablina, Melissa E. Hector, Kaisa Teittinen, Olayinka Raheem, Kirsi Ketola, Shujun Lin, Juergen Kast, Hannu Haapasalo, William C. Hahn, and Jukka Westermarck
Cancer Res 2009 69: 2870-2877. Published Online First March 17, 2009. doi: 10.1158/0008-5472.CAN-08-2760 [Abstract] [Full Text] [PDF] Supplementary Data  

Caveolin-1 Regulates the Antagonistic Pleiotropic Properties of Cellular Senescence through a Novel Mdm2/p53-Mediated Pathway

Janine N. Bartholomew, Daniela Volonte, and Ferruccio Galbiati
Cancer Res 2009 69: 2878-2886. Published Online First March 24, 2009. doi: 10.1158/0008-5472.CAN-08-2857 [Abstract] [Full Text] [PDF] Supplementary Data  

Immune-Induced Epithelial to Mesenchymal Transition In vivo Generates Breast Cancer Stem Cells

Marta Santisteban, Jennifer M. Reiman, Michael K. Asiedu, Marshall D. Behrens, Aziza Nassar, Kimberly R. Kalli, Paul Haluska, James N. Ingle, Lynn C. Hartmann, Masoud H. Manjili, Derek C. Radisky, Soldano Ferrone, and Keith L. Knutson
Cancer Res 2009 69: 2887-2895. Published Online First March 10, 2009. doi: 10.1158/0008-5472.CAN-08-3343 [Abstract] [Full Text] [PDF] Supplementary Data  

Telomere Length in Peripheral Blood Predicts Survival in Clear Cell Renal Cell Carcinoma

Ulrika Svenson, Börje Ljungberg, and Göran Roos
Cancer Res 2009 69: 2896-2901. Published Online First March 24, 2009. doi: 10.1158/0008-5472.CAN-08-3513 [Abstract] [Full Text] [PDF]  

Credentialing a Preclinical Mouse Model of Alveolar Rhabdomyosarcoma

Koichi Nishijo, Qing-Rong Chen, Lei Zhang, Amanda T. McCleish, Andrea Rodriguez, Min Jung Cho, Suresh I. Prajapati, Jonathan A.L. Gelfond, Gary B. Chisholm, Joel E. Michalek, Bruce J. Aronow, Frederic G. Barr, R. Lor Randall, Marc Ladanyi, Stephen J. Qualman, Brian P. Rubin, Robin D. LeGallo, Chiayeng Wang, Javed Khan, and Charles Keller
Cancer Res 2009 69: 2902-2911. doi: 10.1158/0008-5472.CAN-08-3723 [Abstract] [Full Text] [PDF] Supplementary Data  

Clinical Research:

Characterization of ERG, AR and PTEN Gene Status in Circulating Tumor Cells from Patients with Castration-Resistant Prostate Cancer

Gerhardt Attard, Joost F. Swennenhuis, David Olmos, Alison H.M. Reid, Elaine Vickers, Roger A'Hern, Rianne Levink, Frank Coumans, Joana Moreira, Ruth Riisnaes, Nikhil Babu Oommen, George Hawche, Charles Jameson, Emilda Thompson, Ronald Sipkema, Craig P. Carden, Christopher Parker, David Dearnaley, Stan B. Kaye, Colin S. Cooper, Arturo Molina, Michael E. Cox, Leon W.M.M. Terstappen, and Johann S. de Bono
Cancer Res 2009 69: 2912-2918. doi: 10.1158/0008-5472.CAN-08-3667 [Abstract] [Full Text] [PDF] Supplementary Data  

Quantitative Optical Spectroscopy: A Robust Tool for Direct Measurement of Breast Cancer Vascular Oxygenation and Total Hemoglobin Content In vivo

J. Quincy Brown, Lee G. Wilke, Joseph Geradts, Stephanie A. Kennedy, Gregory M. Palmer, and Nirmala Ramanujam
Cancer Res 2009 69: 2919-2926. Published Online First March 17, 2009. doi: 10.1158/0008-5472.CAN-08-3370 [Abstract] [Full Text] [PDF]  

In situ Expression of Tumor Antigens by Messenger RNA–Electroporated Dendritic Cells in Lymph Nodes of Melanoma Patients

Danita H. Schuurhuis, Pauline Verdijk, Gerty Schreibelt, Erik H.J.G. Aarntzen, Nicole Scharenborg, Annemiek de Boer, Mandy W.M.M. van de Rakt, Marieke Kerkhoff, Marie-Jeanne P. Gerritsen, Femke Eijckeler, Johannes J. Bonenkamp, Willeke Blokx, J. Han van Krieken, Otto C. Boerman, Wim J.G. Oyen, Cornelis J.A. Punt, Carl G. Figdor, Gosse J. Adema, and I. Jolanda M. de Vries
Cancer Res 2009 69: 2927-2934. Published Online First March 24, 2009. doi: 10.1158/0008-5472.CAN-08-3920 [Abstract] [Full Text] [PDF]  

Endocrinology:

Association of Estrogen Receptor and Histone Deacetylase 6 Causes Rapid Deacetylation of Tubulin in Breast Cancer Cells

Kotaro Azuma, Tomohiko Urano, Kuniko Horie-Inoue, Shin-ichi Hayashi, Ryuichi Sakai, Yasuyoshi Ouchi, and Satoshi Inoue
Cancer Res 2009 69: 2935-2940. Published Online First March 24, 2009. doi: 10.1158/0008-5472.CAN-08-3458 [Abstract] [Full Text] [PDF]  

Androgen Receptor Controls EGFR and ERBB2 Gene Expression at Different Levels in Prostate Cancer Cell Lines

Jean-Christophe Pignon, Benjamin Koopmansch, Gregory Nolens, Laurence Delacroix, David Waltregny, and Rosita Winkler
Cancer Res 2009 69: 2941-2949. Published Online First March 24, 2009. doi: 10.1158/0008-5472.CAN-08-3760 [Abstract] [Full Text] [PDF] Supplementary Data  

Epidemiology:

Associations between Selected Biomarkers and Prognosis in a Population-Based Pancreatic Cancer Tissue Microarray

Mikiko Takikita, Sean Altekruse, Charles F. Lynch, Mark T. Goodman, Brenda Y. Hernandez, Mark Green, Wendy Cozen, Myles Cockburn, Maria Sibug Saber, Marie Topor, Chris Zeruto, Behnoush Abedi-Ardekani, Marsha E. Reichman, and Stephen M. Hewitt
Cancer Res 2009 69: 2950-2955. Published Online First March 10, 2009. doi: 10.1158/0008-5472.CAN-08-3879 [Abstract] [Full Text] [PDF]  

Genetic Associations of 115 Polymorphisms with Cancers of the Upper Aerodigestive Tract across 10 European Countries: The ARCAGE Project

Cristina Canova, Mia Hashibe, Lorenzo Simonato, Mari Nelis, Andres Metspalu, Pagona Lagiou, Dimitrios Trichopoulos, Wolfgang Ahrens, Iris Pigeot, Franco Merletti, Lorenzo Richiardi, Renato Talamini, Luigi Barzan, Gary J. Macfarlane, Tatiana V. Macfarlane, Ivana Holcátová, Vladimir Bencko, Simone Benhamou, Christine Bouchardy, Kristina Kjaerheim, Ray Lowry, Antonio Agudo, Xavier Castellsagué, David I. Conway, Patricia A. McKinney, Ariana Znaor, Bernard E. McCartan, Claire M. Healy, Manuela Marron, and Paul Brennan
Cancer Res 2009 69: 2956-2965. doi: 10.1158/0008-5472.CAN-08-2604 [Abstract] [Full Text] [PDF]  

Plasma Protein Carbonyls and Breast Cancer Risk in Sisters Discordant for Breast Cancer from the New York Site of the Breast Cancer Family Registry

Jennifer Zipprich, Mary Beth Terry, Yuyan Liao, Meenakshi Agrawal, Irina Gurvich, Ruby Senie, and Regina M. Santella
Cancer Res 2009 69: 2966-2972. doi: 10.1158/0008-5472.CAN-08-3418 [Abstract] [Full Text] [PDF]  

Association between Chronic Atrophic Gastritis and Serum Antibodies to 15 Helicobacter pylori Proteins Measured by Multiplex Serology

Lei Gao, Melanie N. Weck, Angelika Michel, Michael Pawlita, and Hermann Brenner
Cancer Res 2009 69: 2973-2980. Published Online First March 24, 2009. doi: 10.1158/0008-5472.CAN-08-3477 [Abstract] [Full Text] [PDF] Supplementary Data  

Characterization of UGTs Active against SAHA and Association between SAHA Glucuronidation Activity Phenotype with UGT Genotype

Renee M. Balliet, Gang Chen, Carla J. Gallagher, Ryan W. Dellinger, Dongxiao Sun, and Philip Lazarus
Cancer Res 2009 69: 2981-2989. Published Online First March 24, 2009. doi: 10.1158/0008-5472.CAN-08-4143 [Abstract] [Full Text] [PDF]  

Urinary Levels of Tobacco-Specific Nitrosamine Metabolites in Relation to Lung Cancer Development in Two Prospective Cohorts of Cigarette Smokers

Jian-Min Yuan, Woon-Puay Koh, Sharon E. Murphy, Yunhua Fan, Renwei Wang, Steven G. Carmella, Shaomei Han, Katie Wickham, Yu-Tang Gao, Mimi C. Yu, and Stephen S. Hecht
Cancer Res 2009 69: 2990-2995. Published Online First March 24, 2009. doi: 10.1158/0008-5472.CAN-08-4330 [Abstract] [Full Text] [PDF]  

Experimental Therapeutics, Molecular Targets, and Chemical Biology:

Hyperactivation of the Insulin-like Growth Factor Receptor I Signaling Pathway Is an Essential Event for Cisplatin Resistance of Ovarian Cancer Cells

Niels Eckstein, Kati Servan, Barbara Hildebrandt, Anne Pölitz, Georg von Jonquières, Sybille Wolf-Kümmeth, Inge Napierski, Alexandra Hamacher, Matthias U. Kassack, Jan Budczies, Manfred Beier, Manfred Dietel, Brigitte Royer-Pokora, Carsten Denkert, and Hans-Dieter Royer
Cancer Res 2009 69: 2996-3003. Published Online First March 24, 2009. doi: 10.1158/0008-5472.CAN-08-3153 [Abstract] [Full Text] [PDF] Supplementary Data  

Depletion of Guanine Nucleotides Leads to the Mdm2-Dependent Proteasomal Degradation of Nucleostemin

Min Huang, Koji Itahana, Yanping Zhang, and Beverly S. Mitchell
Cancer Res 2009 69: 3004-3012. Published Online First March 24, 2009. doi: 10.1158/0008-5472.CAN-08-3413 [Abstract] [Full Text] [PDF]  

Modulation of Caspase-Independent Cell Death Leads to Resensitization of Imatinib Mesylate–Resistant Cells

Vanessa J. Lavallard, Ludivine A. Pradelli, Audrey Paul, Marie Bénéteau, Arnaud Jacquel, Patrick Auberger, and Jean-Ehrland Ricci
Cancer Res 2009 69: 3013-3020. Published Online First March 24, 2009. doi: 10.1158/0008-5472.CAN-08-2731 [Abstract] [Full Text] [PDF] Supplementary Data  

The MET Receptor Tyrosine Kinase Is a Potential Novel Therapeutic Target for Head and Neck Squamous Cell Carcinoma

Tanguy Y. Seiwert, Ramasamy Jagadeeswaran, Leonardo Faoro, Varalakshmi Janamanchi, Vidya Nallasura, Mohamed El Dinali, Soheil Yala, Rajani Kanteti, Ezra E.W. Cohen, Mark W. Lingen, Leslie Martin, Soundararajan Krishnaswamy, Andres Klein-Szanto, James G. Christensen, Everett E. Vokes, and Ravi Salgia
Cancer Res 2009 69: 3021-3031. Published Online First March 24, 2009. doi: 10.1158/0008-5472.CAN-08-2881 [Abstract] [Full Text] [PDF] Supplementary Data  

FMS-Like Tyrosine Kinase 3–Internal Tandem Duplication Tyrosine Kinase Inhibitors Display a Nonoverlapping Profile of Resistance Mutations In vitro

Nikolas von Bubnoff, Richard A. Engh, Espen Åberg, Jana Sänger, Christian Peschel, and Justus Duyster
Cancer Res 2009 69: 3032-3041. Published Online First March 24, 2009. doi: 10.1158/0008-5472.CAN-08-2923 [Abstract] [Full Text] [PDF] Supplementary Data  

Antitumor Efficacy of the Novel RAF Inhibitor GDC-0879 Is Predicted by BRAF^V600E Mutational Status and Sustained Extracellular Signal-Regulated Kinase/Mitogen-Activated Protein Kinase Pathway Suppression

Klaus P. Hoeflich, Sylvia Herter, Janet Tien, Leo Wong, Leanne Berry, Jocelyn Chan, Carol O'Brien, Zora Modrusan, Somasekar Seshagiri, Mark Lackner, Howard Stern, Edna Choo, Lesley Murray, Lori S. Friedman, and Marcia Belvin
Cancer Res 2009 69: 3042-3051. Published Online First March 10, 2009. doi: 10.1158/0008-5472.CAN-08-3563 [Abstract] [Full Text] [PDF] Supplementary Data  

Dose-Response Relationships for N7-(2-Hydroxyethyl)Guanine Induced by Low-Dose [¹⁴C]Ethylene Oxide: Evidence for a Novel Mechanism of Endogenous Adduct Formation

Debbie A. Marsden, Donald J.L. Jones, Robert G. Britton, Ted Ognibene, Esther Ubick, George E. Johnson, Peter B. Farmer, and Karen Brown
Cancer Res 2009 69: 3052-3059. Published Online First March 10, 2009. doi: 10.1158/0008-5472.CAN-08-4233 [Abstract] [Full Text] [PDF]  

Inhibition of NOTCH Signaling by Gamma Secretase Inhibitor Engages the RB Pathway and Elicits Cell Cycle Exit in T-Cell Acute Lymphoblastic Leukemia Cells

Sudhir S. Rao, Jennifer O'Neil, Cole D. Liberator, James S. Hardwick, Xudong Dai, Theresa Zhang, Edyta Tyminski, Jing Yuan, Nancy E. Kohl, Victoria M. Richon, Lex H.T. Van der Ploeg, Pamela M. Carroll, Giulio F. Draetta, A. Thomas Look, Peter R. Strack, and Christopher G. Winter
Cancer Res 2009 69: 3060-3068. Published Online First March 24, 2009. doi: 10.1158/0008-5472.CAN-08-4295 [Abstract] [Full Text] [PDF] Supplementary Data  

Immunology:

A Key Regulatory Role of the Transcription Factor NFATc2 in Bronchial Adenocarcinoma via CD8⁺ T Lymphocytes

Joachim H. Maxeiner, Roman Karwot, Kerstin Sauer, Petra Scholtes, Ildiko Boross, Michael Koslowski, Özlem Türeci, Rainer Wiewrodt, Markus F. Neurath, Hans A. Lehr, and Susetta Finotto
Cancer Res 2009 69: 3069-3076. Published Online First March 24, 2009. doi: 10.1158/0008-5472.CAN-08-1678 [Abstract] [Full Text] [PDF] Supplementary Data  

Chemokine Expression in Melanoma Metastases Associated with CD8⁺ T-Cell Recruitment

Helena Harlin, Yuru Meng, Amy C. Peterson, Yuanyuan Zha, Maria Tretiakova, Craig Slingluff, Mark McKee, and Thomas F. Gajewski
Cancer Res 2009 69: 3077-3085. Published Online First March 17, 2009. doi: 10.1158/0008-5472.CAN-08-2281 [Abstract] [Full Text] [PDF] Supplementary Data  

Tumor-Infiltrating Regulatory Dendritic Cells Inhibit CD8⁺ T Cell Function via L-Arginine Metabolism

Lyse A. Norian, Paulo C. Rodriguez, Leigh A. O'Mara, Jovanny Zabaleta, Augusto C. Ochoa, Marina Cella, and Paul M. Allen
Cancer Res 2009 69: 3086-3094. Published Online First March 17, 2009. doi: 10.1158/0008-5472.CAN-08-2826 [Abstract] [Full Text] [PDF] Supplementary Data  

GD3, an Overexpressed Tumor-Derived Ganglioside, Mediates the Apoptosis of Activated but not Resting T Cells

Gaurisankar Sa, Tanya Das, Christina Moon, Cynthia M. Hilston, Patricia A. Rayman, Brian I. Rini, Charles S. Tannenbaum, and James H. Finke
Cancer Res 2009 69: 3095-3104. Published Online First March 10, 2009. doi: 10.1158/0008-5472.CAN-08-3776 [Abstract] [Full Text] [PDF] Supplementary Data  

Triggering of Toll-like Receptor 4 Expressed on Human Head and Neck Squamous Cell Carcinoma Promotes Tumor Development and Protects the Tumor from Immune Attack

Miroslaw J. Szczepanski, Malgorzata Czystowska, Marta Szajnik, Malgorzata Harasymczuk, Michael Boyiadzis, Aleksandra Kruk-Zagajewska, Witold Szyfter, Jan Zeromski, and Theresa L. Whiteside
Cancer Res 2009 69: 3105-3113. Published Online First March 24, 2009. doi: 10.1158/0008-5472.CAN-08-3838 [Abstract] [Full Text] [PDF] Supplementary Data  

CTL Activation Using the Natural Low-Affinity Epitope 222-229 from Tyrosinase-Related Protein 1 Leads to Tumor Rejection

Kevin D. Pavelko, Michael J. Hansen, and Larry R. Pease
Cancer Res 2009 69: 3114-3120. Published Online First March 10, 2009. doi: 10.1158/0008-5472.CAN-08-2448 [Abstract] [Full Text] [PDF] Supplementary Data  

Circulating B-Cell Chronic Lymphocytic Leukemia Cells Display Impaired Migration to Lymph Nodes and Bone Marrow

Tanja Nicole Hartmann, Valentin Grabovsky, Wei Wang, Petra Desch, Gabriele Rubenzer, Stefan Wollner, Inbal Binsky, Alexandra Vallon-Eberhard, Anita Sapoznikov, Meike Burger, Idit Shachar, Michal Haran, Marek Honczarenko, Richard Greil, and Ronen Alon
Cancer Res 2009 69: 3121-3130. Published Online First March 17, 2009. doi: 10.1158/0008-5472.CAN-08-4136 [Abstract] [Full Text] [PDF] Supplementary Data  

Molecular Biology, Pathobiology, and Genetics:

Human ZNF312b Promotes the Progression of Gastric Cancer by Transcriptional Activation of the K-ras Gene

In-Sung Song, Nang Su Oh, Hyun-Taek Kim, Ga-Hee Ha, So-Young Jeong, Jeong-Min Kim, Dong-Il Kim, Hyang-Sook Yoo, Cheol-Hee Kim, and Nam-Soon Kim
Cancer Res 2009 69: 3131-3139. Published Online First March 24, 2009. doi: 10.1158/0008-5472.CAN-08-2240 [Abstract] [Full Text] [PDF] Supplementary Data  

Genome-Wide Impact of Androgen Receptor Trapped clone-27 Loss on Androgen-Regulated Transcription in Prostate Cancer Cells

Jerome C. Nwachukwu, Paolo Mita, Rachel Ruoff, Susan Ha, Qianben Wang, S. Joseph Huang, Samir S. Taneja, Myles Brown, William L. Gerald, Michael J. Garabedian, and Susan K. Logan
Cancer Res 2009 69: 3140-3147. Published Online First March 24, 2009. doi: 10.1158/0008-5472.CAN-08-3738 [Abstract] [Full Text] [PDF] Supplementary Data  

Programmed Cell Death Protein 4 Down-regulates Y-Box Binding Protein-1 Expression via a Direct Interaction with Twist1 to Suppress Cancer Cell Growth

Masaki Shiota, Hiroto Izumi, Akihide Tanimoto, Mayu Takahashi, Naoya Miyamoto, Eiji Kashiwagi, Akihiko Kidani, Gen Hirano, Daisuke Masubuchi, Yasushi Fukunaka, Yoshihiro Yasuniwa, Seiji Naito, Shigeru Nishizawa, Yasuyuki Sasaguri, and Kimitoshi Kohno
Cancer Res 2009 69: 3148-3156. Published Online First March 24, 2009. doi: 10.1158/0008-5472.CAN-08-2334 [Abstract] [Full Text] [PDF]  

A Novel Human AlkB Homologue, ALKBH8, Contributes to Human Bladder Cancer Progression

Keiji Shimada, Mitsutoshi Nakamura, Satoshi Anai, Marco De Velasco, Motoyoshi Tanaka, Kazutake Tsujikawa, Yukiteru Ouji, and Noboru Konishi
Cancer Res 2009 69: 3157-3164. Published Online First March 17, 2009. doi: 10.1158/0008-5472.CAN-08-3530 [Abstract] [Full Text] [PDF] Supplementary Data  

Impaired Turnover of Prolactin Receptor Contributes to Transformation of Human Breast Cells

Alexandr Plotnikov, Bentley Varghese, Thai H. Tran, Chengbao Liu, Hallgeir Rui, and Serge Y. Fuchs
Cancer Res 2009 69: 3165-3172. Published Online First March 10, 2009. doi: 10.1158/0008-5472.CAN-08-4033 [Abstract] [Full Text] [PDF] Supplementary Data  

Systems Biology and Emerging Technologies:

Noninvasive Imaging of _Vβ₃ Function as a Predictor of the Antimigratory and Antiproliferative Effects of Dasatinib

Rebecca A. Dumont, Isabel Hildebrandt, Helen Su, Roland Haubner, Gerald Reischl, Johannes G. Czernin, Paul S. Mischel, and Wolfgang A. Weber
Cancer Res 2009 69: 3173-3179. Published Online First March 24, 2009. doi: 10.1158/0008-5472.CAN-08-3390 [Abstract] [Full Text] [PDF]  

Magnetovaccination as a Novel Method to Assess and Quantify Dendritic Cell Tumor Antigen Capture and Delivery to Lymph Nodes

Christopher M. Long, Hanneke W.M. van Laarhoven, Jeff W.M. Bulte, and Hyam I. Levitsky
Cancer Res 2009 69: 3180-3187. Published Online First March 10, 2009. doi: 10.1158/0008-5472.CAN-08-3691 [Abstract] [Full Text] [PDF] Supplementary Data  

Tumor Microenvironment:

Cathepsin G Recruits Osteoclast Precursors via Proteolytic Activation of Protease-Activated Receptor-1

Thomas J. Wilson, Kalyan C. Nannuru, and Rakesh K. Singh
Cancer Res 2009 69: 3188-3195. Published Online First March 17, 2009. doi: 10.1158/0008-5472.CAN-08-1956 [Abstract] [Full Text] [PDF]  

CD47 Regulates Bone Mass and Tumor Metastasis to Bone

Özge Uluçkan, Stephanie N. Becker, Hongju Deng, Wei Zou, Julie L. Prior, David Piwnica-Worms, William A. Frazier, and Katherine N. Weilbaecher
Cancer Res 2009 69: 3196-3204. Published Online First March 10, 2009. doi: 10.1158/0008-5472.CAN-08-3358 [Abstract] [Full Text] [PDF] Supplementary Data  

Naringenin: A Potential Immunomodulator for Inhibiting Lung Fibrosis and Metastasis

Gangjun Du, Lingtao Jin, Xiaofen Han, Zihui Song, Hongyan Zhang, and Wei Liang
Cancer Res 2009 69: 3205-3212. Published Online First March 24, 2009. doi: 10.1158/0008-5472.CAN-08-3393 [Abstract] [Full Text] [PDF] Supplementary Data  

Heterozygosity for Hypoxia Inducible Factor 1 Decreases the Incidence of Thymic Lymphomas in a p53 Mutant Mouse Model

Jessica A. Bertout, Shetal A. Patel, Benjamin H. Fryer, Amy C. Durham, Kelly L. Covello, Kenneth P. Olive, Michael H. Goldschmidt, and M. Celeste Simon
Cancer Res 2009 69: 3213-3220. Published Online First March 17, 2009. doi: 10.1158/0008-5472.CAN-08-4223 [Abstract] [Full Text] [PDF] Supplementary Data  

The EGF/CSF-1 Paracrine Invasion Loop Can Be Triggered by Heregulin β1 and CXCL12

Lorena Hernandez, Tatiana Smirnova, Dmitriy Kedrin, Jeffrey Wyckoff, Liyin Zhu, E. Richard Stanley, Dianne Cox, William J. Muller, Jeffrey W. Pollard, Nico Van Rooijen, and Jeffrey E. Segall
Cancer Res 2009 69: 3221-3227. Published Online First March 17, 2009. doi: 10.1158/0008-5472.CAN-08-2871 [Abstract] [Full Text] [PDF] Supplementary Data  

Functional Alteration of the Lymphoma Stromal Cell Niche by the Cytokine Context: Role of Indoleamine-2,3 Dioxygenase

Hélène Maby-El Hajjami, Patricia Amé-Thomas, Céline Pangault, Olivier Tribut, John DeVos, Rachel Jean, Nadège Bescher, Céline Monvoisin, Joëlle Dulong, Thierry Lamy, Thierry Fest, and Karin Tarte
Cancer Res 2009 69: 3228-3237. Published Online First March 10, 2009. doi: 10.1158/0008-5472.CAN-08-3000 [Abstract] [Full Text] [PDF] Supplementary Data  

Obituary:

Eugenia Calle: In Memoriam (1952–2009)

Christine B. Ambrosone
Cancer Res 2009 69: 3238-3239. Published Online First March 24, 2009. doi: 10.1158/0008-5472.CAN-09-0767 [Full Text] [PDF]  

Corrections:

Correction: Article on TP53 in BRCA1 Breast Tumors

Cancer Res 2009 69: 3240. Published Online First March 24, 2009. doi: 10.1158/0008-5472.CAN-69-7-COR1 [Full Text] [PDF]  

Correction: Article on Red and Processed Meats, Meat Mutagens, and Lung Cancer

Cancer Res 2009 69: 3240. Published Online First March 24, 2009. doi: 10.1158/0008-5472.CAN-69-7-COR2 [Full Text] [PDF]  

Correction: Article on MicroRNAs and DNA Repair

Cancer Res 2009 69: 3240. Published Online First March 24, 2009. doi: 10.1158/0008-5472.CAN-69-7-COR3 [Full Text] [PDF]  

Correction: Review Article on Mesenchymal Stem Cells

Cancer Res 2009 69: 3240. Published Online First March 24, 2009. doi: 10.1158/0008-5472.CAN-69-7-COR4 [Full Text] [PDF]  

To see an article, click its [Full Text] or [PDF] link. To review many abstracts, check the boxes to the left of the titles you want, and click the 'Get All Checked Abstract(s)' button. To see one abstract at a time, click its [Abstract] link.