Reviews:

Genetic Subgrouping of Melanoma Reveals New Opportunities for Targeted Therapy

Keiran S.M. Smalley, Katherine L. Nathanson, and Keith T. Flaherty
Cancer Res 2009 69: 3241-3244. Published Online First April 7, 2009. doi: 10.1158/0008-5472.CAN-08-4305 [Abstract] [Full Text] [PDF]  

New Tricks for Animal MicroRNAs: Targeting of Amino Acid Coding Regions at Conserved and Nonconserved Sites

Isidore Rigoutsos
Cancer Res 2009 69: 3245-3248. Published Online First April 7, 2009. doi: 10.1158/0008-5472.CAN-09-0352 [Abstract] [Full Text] [PDF]  

Priority Reports:

The miR-17/92 Polycistron Is Up-regulated in Sonic Hedgehog–Driven Medulloblastomas and Induced by N-myc in Sonic Hedgehog–Treated Cerebellar Neural Precursors

Paul A. Northcott, Africa Fernandez-L, John P. Hagan, David W. Ellison, Wesia Grajkowska, Yancey Gillespie, Richard Grundy, Timothy Van Meter, James T. Rutka, Carlo M. Croce, Anna Marie Kenney, and Michael D. Taylor
Cancer Res 2009 69: 3249-3255. Published Online First April 7, 2009. doi: 10.1158/0008-5472.CAN-08-4710 [Abstract] [Full Text] [PDF] Supplementary Data  

PTEN Loss Contributes to Erlotinib Resistance in EGFR-Mutant Lung Cancer by Activation of Akt and EGFR

Martin L. Sos, Mirjam Koker, Barbara A. Weir, Stefanie Heynck, Rosalia Rabinovsky, Thomas Zander, Jens M. Seeger, Jonathan Weiss, Florian Fischer, Peter Frommolt, Kathrin Michel, Martin Peifer, Craig Mermel, Luc Girard, Michael Peyton, Adi F. Gazdar, John D. Minna, Levi A. Garraway, Hamid Kashkar, William Pao, Matthew Meyerson, and Roman K. Thomas
Cancer Res 2009 69: 3256-3261. Published Online First April 7, 2009. doi: 10.1158/0008-5472.CAN-08-4055 [Abstract] [Full Text] [PDF] Supplementary Data  

Detection of Precancerous Cervical Lesions Is Differential by Human Papillomavirus Type

Mahboobeh Safaeian, Mark Schiffman, Julia Gage, Diane Solomon, Cosette M. Wheeler, and Philip E. Castle
Cancer Res 2009 69: 3262-3266. Published Online First April 7, 2009. doi: 10.1158/0008-5472.CAN-08-4192 [Abstract] [Full Text] [PDF]  

RelB Enhances Prostate Cancer Growth: Implications for the Role of the Nuclear Factor-B Alternative Pathway in Tumorigenicity

Yong Xu, Sajni Josson, Fang Fang, Terry D. Oberley, Daret K. St. Clair, X. Steven Wan, Yulan Sun, Vasudevan Bakthavatchalu, Anantharaman Muthuswamy, and William H. St. Clair
Cancer Res 2009 69: 3267-3271. Published Online First April 7, 2009. doi: 10.1158/0008-5472.CAN-08-4635 [Abstract] [Full Text] [PDF]  

The L6 Protein TM4SF1 Is Critical for Endothelial Cell Function and Tumor Angiogenesis

Shou-Ching Shih, Andrew Zukauskas, Dan Li, Guanmei Liu, Lay-Hong Ang, Janice A. Nagy, Lawrence F. Brown, and Harold F. Dvorak
Cancer Res 2009 69: 3272-3277. Published Online First April 7, 2009. doi: 10.1158/0008-5472.CAN-08-4886 [Abstract] [Full Text] [PDF] Supplementary Data  

MicroRNA Signature of Primary Pigmented Nodular Adrenocortical Disease: Clinical Correlations and Regulation of Wnt Signaling

Dimitrios Iliopoulos, Eirini I. Bimpaki, Maria Nesterova, and Constantine A. Stratakis
Cancer Res 2009 69: 3278-3282. Published Online First April 7, 2009. doi: 10.1158/0008-5472.CAN-09-0155 [Abstract] [Full Text] [PDF] Supplementary Data  

Cell, Tumor, and Stem Cell Biology:

PTTG Overexpression Promotes Lymph Node Metastasis in Human Esophageal Squamous Cell Carcinoma

Shuang Yan, Cuiqi Zhou, Xiaomin Lou, Zefen Xiao, Hongxia Zhu, Qifeng Wang, Yihua Wang, Ning Lu, Shun He, Qimin Zhan, Siqi Liu, and Ningzhi Xu
Cancer Res 2009 69: 3283-3290. Published Online First April 7, 2009. doi: 10.1158/0008-5472.CAN-08-0367 [Abstract] [Full Text] [PDF]  

Epidermal Growth Factor Receptor/β-Catenin/T-Cell Factor 4/Matrix Metalloproteinase 1: A New Pathway for Regulating Keratinocyte Invasiveness after UVA Irradiation

Christine Jean, Amandine Blanc, Naïs Prade-Houdellier, Loïc Ysebaert, Hélène Hernandez-Pigeon, Talal Al Saati, Marie-José Haure, Addolorata-Maria-Luce Coluccia, Marie Charveron, Eric Delabesse, and Guy Laurent
Cancer Res 2009 69: 3291-3299. Published Online First March 31, 2009. doi: 10.1158/0008-5472.CAN-08-1909 [Abstract] [Full Text] [PDF] Supplementary Data  

Estrogens and Human Papilloma Virus Oncogenes Regulate Human Ether-à-go-go-1 Potassium Channel Expression

Lorenza Díaz, Irais Ceja-Ochoa, Iván Restrepo-Angulo, Fernando Larrea, Euclides Avila-Chávez, Rocío García-Becerra, Elizabeth Borja-Cacho, David Barrera, Elías Ahumada, Patricio Gariglio, Elizabeth Alvarez-Rios, Rodolfo Ocadiz-Delgado, Enrique Garcia-Villa, Elizabeth Hernández-Gallegos, Ignacio Camacho-Arroyo, Angélica Morales, David Ordaz-Rosado, Ethel García-Latorre, Juan Escamilla, Luz Carmen Sánchez-Peña, Milena Saqui-Salces, Armando Gamboa-Dominguez, Eunice Vera, Marisela Uribe-Ramírez, Janet Murbartián, Cindy Sharon Ortiz, Claudia Rivera-Guevara, Andrea De Vizcaya-Ruiz, and Javier Camacho
Cancer Res 2009 69: 3300-3307. Published Online First April 7, 2009. doi: 10.1158/0008-5472.CAN-08-2036 [Abstract] [Full Text] [PDF]  

_vβ₃/_vβ₅ Integrins-FAK-RhoB: A Novel Pathway for Hypoxia Regulation in Glioblastoma

Nicolas Skuli, Sylvie Monferran, Caroline Delmas, Gilles Favre, Jacques Bonnet, Christine Toulas, and Elizabeth Cohen-Jonathan Moyal
Cancer Res 2009 69: 3308-3316. Published Online First April 7, 2009. doi: 10.1158/0008-5472.CAN-08-2158 [Abstract] [Full Text] [PDF] Supplementary Data  

Mirk/Dyrk1B Maintains the Viability of Quiescent Pancreatic Cancer Cells by Reducing Levels of Reactive Oxygen Species

Xiaobing Deng, Daina Z. Ewton, and Eileen Friedman
Cancer Res 2009 69: 3317-3324. Published Online First April 7, 2009. doi: 10.1158/0008-5472.CAN-08-2903 [Abstract] [Full Text] [PDF] Supplementary Data  

Tripeptidyl Peptidase II Plays a Role in the Radiation Response of Selected Primary Cell Types but not Based on Nuclear Translocation and p53 Stabilization

Elke Firat, Chizuko Tsurumi, Simone Gaedicke, Jisen Huai, and Gabriele Niedermann
Cancer Res 2009 69: 3325-3331. Published Online First April 7, 2009. doi: 10.1158/0008-5472.CAN-08-3269 [Abstract] [Full Text] [PDF] Supplementary Data  

LEF1 in Androgen-Independent Prostate Cancer: Regulation of Androgen Receptor Expression, Prostate Cancer Growth, and Invasion

Yirong Li, Longgui Wang, Miao Zhang, Jonathan Melamed, Xiaomei Liu, Robert Reiter, Jianjun Wei, Yi Peng, Xuanyi Zou, Angel Pellicer, Michael J. Garabedian, Anna Ferrari, and Peng Lee
Cancer Res 2009 69: 3332-3338. Published Online First April 7, 2009. doi: 10.1158/0008-5472.CAN-08-3380 [Abstract] [Full Text] [PDF]  

Androgen-Induced Coactivator ANCCA Mediates Specific Androgen Receptor Signaling in Prostate Cancer

June X. Zou, Linlang Guo, Alexey S. Revenko, Clifford G. Tepper, Abigael T. Gemo, Hsing-Jien Kung, and Hong-Wu Chen
Cancer Res 2009 69: 3339-3346. Published Online First March 24, 2009. doi: 10.1158/0008-5472.CAN-08-3440 [Abstract] [Full Text] [PDF] Supplementary Data  

The Cell Fate Determination Factor Dachshund Inhibits Androgen Receptor Signaling and Prostate Cancer Cellular Growth

Kongming Wu, Sanjay Katiyar, Agnes Witkiewicz, Anping Li, Peter McCue, Liang-Nian Song, Lifeng Tian, Ming Jin, and Richard G. Pestell
Cancer Res 2009 69: 3347-3355. Published Online First April 7, 2009. doi: 10.1158/0008-5472.CAN-08-3821 [Abstract] [Full Text] [PDF] Supplementary Data  

The Role of microRNA-221 and microRNA-222 in Androgen-Independent Prostate Cancer Cell Lines

Tong Sun, Qianben Wang, Steven Balk, Myles Brown, Gwo-Shu Mary Lee, and Philip Kantoff
Cancer Res 2009 69: 3356-3363. Published Online First April 7, 2009. doi: 10.1158/0008-5472.CAN-08-4112 [Abstract] [Full Text] [PDF]  

A Primary Xenograft Model of Small-Cell Lung Cancer Reveals Irreversible Changes in Gene Expression Imposed by Culture In vitro

Vincent C. Daniel, Luigi Marchionni, Jared S. Hierman, Jonathan T. Rhodes, Wendy L. Devereux, Charles M. Rudin, Rex Yung, Giovanni Parmigiani, Marion Dorsch, Craig D. Peacock, and D. Neil Watkins
Cancer Res 2009 69: 3364-3373. Published Online First April 7, 2009. doi: 10.1158/0008-5472.CAN-08-4210 [Abstract] [Full Text] [PDF] Supplementary Data  

Thrombin Induces Tumor Cell Cycle Activation and Spontaneous Growth by Down-regulation of p27^Kip1, in Association with the Up-regulation of Skp2 and MiR-222

Liang Hu, Sherif Ibrahim, Cynthia Liu, Jeffrey Skaar, Michele Pagano, and Simon Karpatkin
Cancer Res 2009 69: 3374-3381. Published Online First April 7, 2009. doi: 10.1158/0008-5472.CAN-08-4290 [Abstract] [Full Text] [PDF] Supplementary Data  

Aldehyde Dehydrogenase 1 Is a Marker for Normal and Malignant Human Colonic Stem Cells (SC) and Tracks SC Overpopulation during Colon Tumorigenesis

Emina H. Huang, Mark J. Hynes, Tao Zhang, Christophe Ginestier, Gabriela Dontu, Henry Appelman, Jeremy Z. Fields, Max S. Wicha, and Bruce M. Boman
Cancer Res 2009 69: 3382-3389. Published Online First March 31, 2009. doi: 10.1158/0008-5472.CAN-08-4418 [Abstract] [Full Text] [PDF]  

Non–Small Cell Lung Cancer Exhibits Transcript Overexpression of Genes Associated with Homologous Recombination and DNA Replication Pathways

Silvia Saviozzi, Paolo Ceppi, Silvia Novello, Paolo Ghio, Marco Lo Iacono, Piero Borasio, Alberto Cambieri, Marco Volante, Mauro Papotti, Raffaele A. Calogero, and Giorgio V. Scagliotti
Cancer Res 2009 69: 3390-3396. Published Online First April 7, 2009. doi: 10.1158/0008-5472.CAN-08-2981 [Abstract] [Full Text] [PDF] Supplementary Data  

Association of LETM1 and MRPL36 Contributes to the Regulation of Mitochondrial ATP Production and Necrotic Cell Death

Longzhen Piao, Yuwen Li, Soung Jung Kim, Hee Sun Byun, Song Mei Huang, Soon-Kyung Hwang, Keum-Jin Yang, Kyeong Ah Park, Minho Won, Janghee Hong, Gang Min Hur, Jeong Ho Seok, Minho Shong, Myung-Haing Cho, Derek P. Brazil, Brian A. Hemmings, and Jongsun Park
Cancer Res 2009 69: 3397-3404. Published Online First March 24, 2009. doi: 10.1158/0008-5472.CAN-08-3235 [Abstract] [Full Text] [PDF] Supplementary Data  

Transcriptional Regulation of Estrogen Receptor- by p53 in Human Breast Cancer Cells

Stephanie Harkey Shirley, Joyce E. Rundhaug, Jie Tian, Noirin Cullinan-Ammann, Isabel Lambertz, Claudio J. Conti, and Robin Fuchs-Young
Cancer Res 2009 69: 3405-3414. Published Online First April 7, 2009. doi: 10.1158/0008-5472.CAN-08-3628 [Abstract] [Full Text] [PDF] Supplementary Data  

Attenuated Transforming Growth Factor β Signaling Promotes Nuclear Factor-B Activation in Head and Neck Cancer

Jonah Cohen, Zhong Chen, Shi-Long Lu, Xin Ping Yang, Pattatheyil Arun, Reza Ehsanian, Matthew S. Brown, Hai Lu, Bin Yan, Oumou Diallo, Xiao-Jing Wang, and Carter Van Waes
Cancer Res 2009 69: 3415-3424. Published Online First April 7, 2009. doi: 10.1158/0008-5472.CAN-08-3704 [Abstract] [Full Text] [PDF] Supplementary Data  

Clinical Research:

14-3-3 Overexpression Defines High Risk for Breast Cancer Recurrence and Promotes Cancer Cell Survival

Christopher L. Neal, Jun Yao, Wentao Yang, Xiaoyan Zhou, Nina T. Nguyen, Jing Lu, Christopher G. Danes, Hua Guo, Keng-Hsueh Lan, Joe Ensor, Walter Hittelman, Mien-Chie Hung, and Dihua Yu
Cancer Res 2009 69: 3425-3432. Published Online First March 24, 2009. doi: 10.1158/0008-5472.CAN-08-2765 [Abstract] [Full Text] [PDF] Supplementary Data  

Endocrinology:

Osteoblast-Derived Factors Induce an Expression Signature that Identifies Prostate Cancer Metastasis and Hormonal Progression

Gang Wang, Simon Haile, Barbara Comuzzi, Amy H. Tien, Jun Wang, Theresa M.K. Yong, Anca E. Jelescu-Bodos, Natalie Blaszczyk, Robert L. Vessella, Bassam A. Masri, and Marianne D. Sadar
Cancer Res 2009 69: 3433-3442. Published Online First April 7, 2009. doi: 10.1158/0008-5472.CAN-08-3506 [Abstract] [Full Text] [PDF] Supplementary Data  

Activation of the PI3 Kinase Pathway By Retinoic Acid Mediates Sodium/Iodide Symporter Induction and Iodide Transport in MCF-7 Breast Cancer Cells

Emi Ohashi, Takahiko Kogai, Hiroyuki Kagechika, and Gregory A. Brent
Cancer Res 2009 69: 3443-3450. Published Online First April 7, 2009. doi: 10.1158/0008-5472.CAN-08-3234 [Abstract] [Full Text] [PDF]  

Epidemiology:

Functional Role of S100A14 Genetic Variants and Their Association with Esophageal Squamous Cell Carcinoma

Hongyan Chen, Dianke Yu, Aiping Luo, Wen Tan, Chunpeng Zhang, Dan Zhao, Ming Yang, Junniao Liu, Dongxin Lin, and Zhihua Liu
Cancer Res 2009 69: 3451-3457. Published Online First April 7, 2009. doi: 10.1158/0008-5472.CAN-08-4231 [Abstract] [Full Text] [PDF] Supplementary Data  

Experimental Therapeutics, Molecular Targets, and Chemical Biology:

Suppression of Human Solid Tumor Growth in Mice by Intratumor and Systemic Inoculation of Histidine-Rich and pH-Dependent Host Defense–like Lytic Peptides

Arik Makovitzki, Avner Fink, and Yechiel Shai
Cancer Res 2009 69: 3458-3463. Published Online First April 7, 2009. doi: 10.1158/0008-5472.CAN-08-3021 [Abstract] [Full Text] [PDF] Supplementary Data  

Noninvasive Detection of Lentiviral-Mediated Choline Kinase Targeting in a Human Breast Cancer Xenograft

Balaji Krishnamachary, Kristine Glunde, Flonne Wildes, Noriko Mori, Tomoyo Takagi, Venu Raman, and Zaver M. Bhujwalla
Cancer Res 2009 69: 3464-3471. Published Online First March 31, 2009. doi: 10.1158/0008-5472.CAN-08-4120 [Abstract] [Full Text] [PDF]  

Human Glioblastoma–Derived Cancer Stem Cells: Establishment of Invasive Glioma Models and Treatment with Oncolytic Herpes Simplex Virus Vectors

Hiroaki Wakimoto, Santosh Kesari, Christopher J. Farrell, William T. Curry, Jr., Cecile Zaupa, Manish Aghi, Toshihiko Kuroda, Anat Stemmer-Rachamimov, Khalid Shah, Ta-Chiang Liu, Deva S. Jeyaretna, Jason Debasitis, Jan Pruszak, Robert L. Martuza, and Samuel D. Rabkin
Cancer Res 2009 69: 3472-3481. Published Online First April 7, 2009. doi: 10.1158/0008-5472.CAN-08-3886 [Abstract] [Full Text] [PDF] Supplementary Data  

Connective Tissue Growth Factor Confers Drug Resistance in Breast Cancer through Concomitant Up-regulation of Bcl-xL and cIAP1

Ming-Yang Wang, Pai-Sheng Chen, Ekambaranellore Prakash, Hsing-Chih Hsu, Hsin-Yi Huang, Ming-Tsan Lin, King-Jen Chang, and Min-Liang Kuo
Cancer Res 2009 69: 3482-3491. Published Online First April 7, 2009. doi: 10.1158/0008-5472.CAN-08-2524 [Abstract] [Full Text] [PDF] Supplementary Data  

Histone Deacetylase Inhibitor Sodium Butyrate Enhances the Cell Killing Effect of Psoralen plus UVA by Attenuating Nucleotide Excision Repair

Tatsushi Toyooka and Yuko Ibuki
Cancer Res 2009 69: 3492-3500. Published Online First April 7, 2009. doi: 10.1158/0008-5472.CAN-08-2546 [Abstract] [Full Text] [PDF] Supplementary Data  

Critical Role and Regulation of Transcription Factor FoxM1 in Human Gastric Cancer Angiogenesis and Progression

Qiang Li, Nu Zhang, Zhiliang Jia, Xiangdong Le, Bingbing Dai, Daoyan Wei, Suyun Huang, Dongfeng Tan, and Keping Xie
Cancer Res 2009 69: 3501-3509. Published Online First April 7, 2009. doi: 10.1158/0008-5472.CAN-08-3045 [Abstract] [Full Text] [PDF] Supplementary Data  

Inhibition of Ataxia Telangiectasia Mutated Kinase Activity Enhances TRAIL-Mediated Apoptosis in Human Melanoma Cells

Vladimir N. Ivanov, Hongning Zhou, Michael A. Partridge, and Tom K. Hei
Cancer Res 2009 69: 3510-3519. Published Online First April 7, 2009. doi: 10.1158/0008-5472.CAN-08-3883 [Abstract] [Full Text] [PDF] Supplementary Data  

Dual Inhibition of Class IA Phosphatidylinositol 3-Kinase and Mammalian Target of Rapamycin as a New Therapeutic Option for T-Cell Acute Lymphoblastic Leukemia

Francesca Chiarini, Federica Falà, Pier Luigi Tazzari, Francesca Ricci, Annalisa Astolfi, Andrea Pession, Pasqualepaolo Pagliaro, James A. McCubrey, and Alberto M. Martelli
Cancer Res 2009 69: 3520-3528. Published Online First April 7, 2009. doi: 10.1158/0008-5472.CAN-08-4884 [Abstract] [Full Text] [PDF] Supplementary Data  

Guanylyl Cyclase C Prevents Colon Cancer Metastasis by Regulating Tumor Epithelial Cell Matrix Metalloproteinase-9

Wilhelm J. Lubbe, David S. Zuzga, Zengyi Zhou, Weili Fu, Joshua Pelta-Heller, Ruth J. Muschel, Scott A. Waldman, and Giovanni M. Pitari
Cancer Res 2009 69: 3529-3536. Published Online First March 31, 2009. doi: 10.1158/0008-5472.CAN-09-0067 [Abstract] [Full Text] [PDF]  

Immunology:

Lineage-Specific T-Cell Responses to Cancer Mucosa Antigen Oppose Systemic Metastases without Mucosal Inflammatory Disease

Adam E. Snook, Peng Li, Benjamin J. Stafford, Elizabeth J. Faul, Lan Huang, Ruth C. Birbe, Alessandro Bombonati, Stephanie Schulz, Matthias J. Schnell, Laurence C. Eisenlohr, and Scott A. Waldman
Cancer Res 2009 69: 3537-3544. Published Online First April 7, 2009. doi: 10.1158/0008-5472.CAN-08-3386 [Abstract] [Full Text] [PDF]  

Immune Rejection of Mouse Tumors Expressing Mutated Self

Fei Duan, Yun Lin, Cailian Liu, Manuel E. Engelhorn, Adam D. Cohen, Michael Curran, Shimon Sakaguchi, Taha Merghoub, Stephanie Terzulli, Jedd D. Wolchok, and Alan N. Houghton
Cancer Res 2009 69: 3545-3553. Published Online First April 7, 2009. doi: 10.1158/0008-5472.CAN-08-2779 [Abstract] [Full Text] [PDF] Supplementary Data  

Lack of Muc1-Regulated β-Catenin Stability Results in Aberrant Expansion of CD11b⁺Gr1⁺ Myeloid-Derived Suppressor Cells from the Bone Marrow

Tze Wei Poh, Judy M. Bradley, Pinku Mukherjee, and Sandra J. Gendler
Cancer Res 2009 69: 3554-3562. Published Online First April 7, 2009. doi: 10.1158/0008-5472.CAN-08-3806 [Abstract] [Full Text] [PDF] Supplementary Data  

Natural Killer Cell IFN- Levels Predict Long-term Survival with Imatinib Mesylate Therapy in Gastrointestinal Stromal Tumor–Bearing Patients

Cédric Ménard, Jean-Yves Blay, Christophe Borg, Stefan Michiels, François Ghiringhelli, Caroline Robert, Céline Nonn, Nathalie Chaput, Julien Taïeb, Nicolas F. Delahaye, Caroline Flament, Jean-François Emile, Axel Le Cesne, and Laurence Zitvogel
Cancer Res 2009 69: 3563-3569. Published Online First April 7, 2009. doi: 10.1158/0008-5472.CAN-08-3807 [Abstract] [Full Text] [PDF]  

Molecular Biology, Pathobiology, and Genetics:

Tobacco Smoke Induces Polycomb-Mediated Repression of Dickkopf-1 in Lung Cancer Cells

Mustafa Hussain, Mahadev Rao, Ashley E. Humphries, Julie A. Hong, Fang Liu, Maocheng Yang, Diana Caragacianu, and David S. Schrump
Cancer Res 2009 69: 3570-3578. Published Online First April 7, 2009. doi: 10.1158/0008-5472.CAN-08-2807 [Abstract] [Full Text] [PDF] Supplementary Data  

Identification of Copy Number Abnormalities and Inactivating Mutations in Two Negative Regulators of Nuclear Factor-B Signaling Pathways in Waldenström's Macroglobulinemia

Esteban Braggio, Jonathan J. Keats, Xavier Leleu, Scott Van Wier, Victor H. Jimenez-Zepeda, Riccardo Valdez, Roelandt F.J. Schop, Tammy Price-Troska, Kimberly Henderson, Antonio Sacco, Feda Azab, Philip Greipp, Morie Gertz, Suzanne Hayman, S. Vincent Rajkumar, John Carpten, Marta Chesi, Michael Barrett, A. Keith Stewart, Ahmet Dogan, P. Leif Bergsagel, Irene M. Ghobrial, and Rafael Fonseca
Cancer Res 2009 69: 3579-3588. Published Online First April 7, 2009. doi: 10.1158/0008-5472.CAN-08-3701 [Abstract] [Full Text] [PDF] Supplementary Data  

Defective Repair of Oxidative DNA Damage in Triple-Negative Breast Cancer Confers Sensitivity to Inhibition of Poly(ADP-Ribose) Polymerase

Elizabeth Alli, Vandana B. Sharma, Preethi Sunderesakumar, and James M. Ford
Cancer Res 2009 69: 3589-3596. Published Online First April 7, 2009. doi: 10.1158/0008-5472.CAN-08-4016 [Abstract] [Full Text] [PDF] Supplementary Data  

Characterization of the HDAC1 Complex That Regulates the Sensitivity of Cancer Cells to Oxidative Stress

Takuya Kato, Yohei Shimono, Masaki Hasegawa, Mayumi Jijiwa, Atsushi Enomoto, Naoya Asai, Yoshiki Murakumo, and Masahide Takahashi
Cancer Res 2009 69: 3597-3604. Published Online First April 7, 2009. doi: 10.1158/0008-5472.CAN-08-4368 [Abstract] [Full Text] [PDF] Supplementary Data  

Clock-Cancer Connection in Non–Hodgkin's Lymphoma: A Genetic Association Study and Pathway Analysis of the Circadian Gene Cryptochrome 2

Aaron E. Hoffman, Tongzhang Zheng, Richard G. Stevens, Yue Ba, Yawei Zhang, Derek Leaderer, Chunhui Yi, Theodore R. Holford, and Yong Zhu
Cancer Res 2009 69: 3605-3613. Published Online First March 24, 2009. doi: 10.1158/0008-5472.CAN-08-4572 [Abstract] [Full Text] [PDF] Supplementary Data  

The Role of the Mouse Y Chromosome on Susceptibility to Testicular Germ Cell Tumors

Philip D. Anderson, Man-Yee Lam, Christophe Poirier, Colin E. Bishop, and Joseph H. Nadeau
Cancer Res 2009 69: 3614-3618. Published Online First April 7, 2009. doi: 10.1158/0008-5472.CAN-08-4881 [Abstract] [Full Text] [PDF] Supplementary Data  

Src-Induced Cisplatin Resistance Mediated by Cell-to-Cell Communication

Elizabeth Peterson-Roth, Cathleen M. Brdlik, and Peter M. Glazer
Cancer Res 2009 69: 3619-3624. Published Online First April 7, 2009. doi: 10.1158/0008-5472.CAN-08-0985 [Abstract] [Full Text] [PDF]  

High Incidence of Protein-Truncating TP53 Mutations in BRCA1-Related Breast Cancer

Henne Holstege, Simon A. Joosse, Conny Th. M. van Oostrom, Petra M. Nederlof, Annemieke de Vries, and Jos Jonkers
Cancer Res 2009 69: 3625-3633. Published Online First March 31, 2009. doi: 10.1158/0008-5472.CAN-08-3426 [Abstract] [Full Text] [PDF] Supplementary Data  

SCUBE2 Suppresses Breast Tumor Cell Proliferation and Confers a Favorable Prognosis in Invasive Breast Cancer

Chien-Jui Cheng, Yuh-Charn Lin, Ming-Tzu Tsai, Ching-Shyang Chen, Mao-Chih Hsieh, Chi-Long Chen, and Ruey-Bing Yang
Cancer Res 2009 69: 3634-3641. doi: 10.1158/0008-5472.CAN-08-3615 [Abstract] [Full Text] [PDF] Supplementary Data  

Oxidation Status of Human OGG1-S326C Polymorphic Variant Determines Cellular DNA Repair Capacity

Anne Bravard, Monique Vacher, Eva Moritz, Laurence Vaslin, Janet Hall, Bernd Epe, and J. Pablo Radicella
Cancer Res 2009 69: 3642-3649. Published Online First April 7, 2009. doi: 10.1158/0008-5472.CAN-08-3943 [Abstract] [Full Text] [PDF] Supplementary Data  

Clinical Predictors for Germline Mutations in Head and Neck Paraganglioma Patients: Cost Reduction Strategy in Genetic Diagnostic Process as Fall-Out

Hartmut P.H. Neumann, Zoran Erlic, Carsten C. Boedeker, Lisa A. Rybicki, Mercedes Robledo, Mario Hermsen, Francesca Schiavi, Maurizio Falcioni, Pingling Kwok, Catherine Bauters, Karen Lampe, Markus Fischer, Emily Edelman, Diana E. Benn, Bruce G. Robinson, Stefanie Wiegand, Gerd Rasp, Boris A. Stuck, Michael M. Hoffmann, Maren Sullivan, Maria A. Sevilla, Marjan M. Weiss, Mariola Peczkowska, Agata Kubaszek, Pascal Pigny, Robyn L. Ward, Diana Learoyd, Michael Croxson, Dmitry Zabolotny, Svetlana Yaremchuk, Wolfgang Draf, Mihaela Muresan, Robert R. Lorenz, Stephan Knipping, Michael Strohm, Gerhard Dyckhoff, Christoph Matthias, Nicole Reisch, Simon F. Preuss, Dirk Eβer, Martin A. Walter, Holger Kaftan, Timo Stöver, Christian Fottner, Harald Gorgulla, Mahdi Malekpour, Masoud Motasaddi Zarandy, Jörg Schipper, Christoph Brase, Alexander Glien, Matthias Kühnemund, Sven Koscielny, Peter Schwerdtfeger, Matti Välimäki, Witold Szyfter, Ulrich Finckh, Klaus Zerres, Alberto Cascon, Giuseppe Opocher, Gerd J. Ridder, Andrzej Januszewicz, Carlos Suarez, and Charis Eng
Cancer Res 2009 69: 3650-3656. Published Online First April 7, 2009. doi: 10.1158/0008-5472.CAN-08-4057 [Abstract] [Full Text] [PDF] Supplementary Data  

A CreER-Based Random Induction Strategy for Modeling Translocation-Associated Sarcomas in Mice

Malay Haldar, Matthew L. Hedberg, Matthew F. Hockin, and Mario R. Capecchi
Cancer Res 2009 69: 3657-3664. Published Online First April 7, 2009. doi: 10.1158/0008-5472.CAN-08-4127 [Abstract] [Full Text] [PDF] Supplementary Data  

Phosphorylation of TRAF2 within Its RING Domain Inhibits Stress-Induced Cell Death by Promoting IKK and Suppressing JNK Activation

Gregory S. Thomas, Laiqun Zhang, Ken Blackwell, and Hasem Habelhah
Cancer Res 2009 69: 3665-3672. Published Online First March 31, 2009. doi: 10.1158/0008-5472.CAN-08-4867 [Abstract] [Full Text] [PDF] Supplementary Data  

IFR-9/STAT2 Functional Interaction Drives Retinoic Acid–Induced Gene G Expression Independently of STAT1

Ye-Jiang Lou, Xiao-Rong Pan, Pei-Min Jia, Dong Li, Shu Xiao, Zhang-Lin Zhang, Sai-Juan Chen, Zhu Chen, and Jian-Hua Tong
Cancer Res 2009 69: 3673-3680. Published Online First April 7, 2009. doi: 10.1158/0008-5472.CAN-08-4922 [Abstract] [Full Text] [PDF]  

Genetic Mutations Associated with Cigarette Smoking in Pancreatic Cancer

Amanda Blackford, Giovanni Parmigiani, Thomas W. Kensler, Christopher Wolfgang, Siân Jones, Xiaosong Zhang, D. Willams Parsons, Jimmy Cheng-Ho Lin, Rebecca J. Leary, James R. Eshleman, Michael Goggins, Elizabeth M. Jaffee, Christine A. Iacobuzio-Donahue, Anirban Maitra, Alison Klein, John L. Cameron, Kelly Olino, Richard Schulick, Jordan Winter, Bert Vogelstein, Victor E. Velculescu, Kenneth W. Kinzler, and Ralph H. Hruban
Cancer Res 2009 69: 3681-3688. Published Online First April 7, 2009. doi: 10.1158/0008-5472.CAN-09-0015 [Abstract] [Full Text] [PDF] Supplementary Data  

Oncogenic Kras Requires Simultaneous PI3K Signaling to Induce ERK Activation and Transform Thyroid Epithelial Cells In vivo

Kelly A. Miller, Nicole Yeager, Kristen Baker, Xiao-Hui Liao, Samuel Refetoff, and Antonio Di Cristofano
Cancer Res 2009 69: 3689-3694. Published Online First April 7, 2009. doi: 10.1158/0008-5472.CAN-09-0024 [Abstract] [Full Text] [PDF] Supplementary Data  

Prevention:

Identification of a Biphasic Role for Genistein in the Regulation of Prostate Cancer Growth and Metastasis

Lara H. El Touny and Partha P. Banerjee
Cancer Res 2009 69: 3695-3703. Published Online First April 7, 2009. doi: 10.1158/0008-5472.CAN-08-2958 [Abstract] [Full Text] [PDF] Supplementary Data  

Atg5 Regulates Phenethyl Isothiocyanate–Induced Autophagic and Apoptotic Cell Death in Human Prostate Cancer Cells

Ajay Bommareddy, Eun-Ryeong Hahm, Dong Xiao, Anna A. Powolny, Alfred L. Fisher, Yu Jiang, and Shivendra V. Singh
Cancer Res 2009 69: 3704-3712. Published Online First March 31, 2009. doi: 10.1158/0008-5472.CAN-08-4344 [Abstract] [Full Text] [PDF] Supplementary Data  

Systems Biology and Emerging Technologies:

Combined Integrin Phosphoproteomic Analyses and Small Interfering RNA–Based Functional Screening Identify Key Regulators for Cancer Cell Adhesion and Migration

Yanling Chen, Bingwen Lu, Qingkai Yang, Colleen Fearns, John R. Yates, III, and Jiing-Dwan Lee
Cancer Res 2009 69: 3713-3720. Published Online First April 7, 2009. doi: 10.1158/0008-5472.CAN-08-2515 [Abstract] [Full Text] [PDF] Supplementary Data  

Corrections:

Correction: Article on Activation of EZH2 by HPV

Cancer Res 2009 69: 3721. Published Online First April 7, 2009. doi: 10.1158/0008-5472.CAN-69-8-COR1 [Full Text] [PDF]  

Correction: Article on In vitro Acquired Resistance to 17-AAG

Cancer Res 2009 69: 3721. Published Online First April 7, 2009. doi: 10.1158/0008-5472.CAN-69-8-COR2 [Full Text] [PDF]  

Correction: Article on Activation of the MYC Signature in Early HCC

Cancer Res 2009 69: 3721. Published Online First April 7, 2009. doi: 10.1158/0008-5472.CAN-69-8-COR3 [Full Text] [PDF]  

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