PT  - JOURNAL ARTICLE
AU  - Stevenson, J. L.
AU  - von Haam, Emmerich
TI  - Induction of Kidney Tumors in Mice by the Use of 20-Methylcholanthrene-impregnated Strings
DP  - 1962 Nov 01
TA  - Cancer Research
PG  - 1177--1179
VI  - 22
IP  - 10
4099  - http://cancerres.aacrjournals.org/content/22/10/1177.short
4100  - http://cancerres.aacrjournals.org/content/22/10/1177.full
SO  - Cancer Res1962 Nov 01; 22
AB  - Cotton strings impregnated with 20-methylcholanthrene were placed in the right kidney of 34 male mice. Nine renal carcinomas and nine spindle-cell sarcomas were produced. Sixteen animals showed no tumor. Whereas the transitional epithelium of the mouse kidney seems responsive to induction of neoplasia by 20-methylcholanthrene, the renal parenchyma appears resistant. The method herein presented is recommended as a useful tool for the study of renal carcinogenesis. ©1962 American Association for Cancer Research.