PT - JOURNAL ARTICLE AU - Stevenson, J. L. AU - von Haam, Emmerich TI - Induction of Kidney Tumors in Mice by the Use of 20-Methylcholanthrene-impregnated Strings DP - 1962 Nov 01 TA - Cancer Research PG - 1177--1179 VI - 22 IP - 10 4099 - http://cancerres.aacrjournals.org/content/22/10/1177.short 4100 - http://cancerres.aacrjournals.org/content/22/10/1177.full SO - Cancer Res1962 Nov 01; 22 AB - Cotton strings impregnated with 20-methylcholanthrene were placed in the right kidney of 34 male mice. Nine renal carcinomas and nine spindle-cell sarcomas were produced. Sixteen animals showed no tumor. Whereas the transitional epithelium of the mouse kidney seems responsive to induction of neoplasia by 20-methylcholanthrene, the renal parenchyma appears resistant. The method herein presented is recommended as a useful tool for the study of renal carcinogenesis. ©1962 American Association for Cancer Research.