Table 1.

Knockdown and resensitization assays were carried out a total of 4 times by using cisplatin-resistant PEO4 cells for genes selected following first round analysis (see Supplementary Table S2 for results of first round analysis)

Gene symbolPlatinum resensitization ratioP
FAK1.380.07
FOLR21.400.004
HDAC41.550.02
MYC1.400.25
PIK3R11.970.04
STAT11.730.0002

NOTE: Platinum resensitization ratio is defined. Quadruplicate data were analyzed by Student's t test for significant difference in cisplatin-induced caspase 3/7 induction between test gene siRNA-transfected cells and siRNA controls.