Table 2

BRCA2 polymorphisms and unclassified variants

PatientVariantCodonExonEffectBICComment
MBCa-105972 C/TThr1915Met11MissenseReported 1 time (6%)Frequent polymorphism
MBC-14, 15IVS11 + 79del4bIntron 11NoneReported 1 time (28%)Frequent polymorphism
G2c7081 A/GIle2285Val12MissenseReported 8 timesRare polymorphism
  • a MBC, male breast cancer.

  • b IVS, intronic variant.

  • c G, Gynecomastia.