Table 1

Incidence of CpG island methylation for ER and E-cad genes in human breast tumors

Tumor type% ER methylation% E-cad methylation% ER and E-cad methylation% ER or E-cad methylation
All49% (54/111)48% (53/11135% (39/111)61% (68/111)
DCIS34% (12/35)31% (11/35)21% (7/35)46% (16/35)
IDC52% (25/48)52% (25/48)38% (18/48)67% (32/48)
LA/MDC61% (17/28)61% (17/28)50% (14/28)71% (20/28)
P (trend) M-Ha χ20.0340.0190.0130.032
  • a M-H, Mantel-Haenszel.