Table 2

Somatic mutations of the LKB1 gene in intestinal hamartomatous polyps from PJS patients

PolypExonCodonSomatic mutationProtein change
PLK276-1P15216–217C insertionTruncation at codon 264–265
PLK76P16263–265TTGT deletionTruncation at codon 286–287
PLK76P26263–265TTGT deletionTruncation at codon 286–287
PLK76P56263–265TTGT deletionTruncation at codon 286–287
PLK76P66263–265TTGT deletionTruncation at codon 286–287