Table 2

Relative quantitation of in situ hybridization of granulin mRNA in normal brain and primary brain tumors

TissueNo. of silver grains/mm2Average no. of silver grains/cell
Normal brain (n = 2)501.6
1605.3
Pilocytic astrocytoma (n = 3)3,8009.6
3,9007.3
4,5007.7
Oligodendroglioma (n = 2)9,50020.2
17,00021.2
Anaplastic astrocytoma (n = 2)17,00029.7
22,00015.2
Glioblastoma multiforme (n = 3)20,00025.9
27,00032.3
30,00053.6