Table 4

Change in serum PSA after intraprostatic delivery of CV706

Patient no.Dose levelPre-CV706 serum PSA (ng/ml)Post-CV706 serum PSA (ng/ml) nadirChange in serum PSA
1158.737.1−37%
2159.7N/CaN/C
3117.612.1−31%
4210.9N/CN/C
5211.88.0−32%
6220.911.0−47%
7314.6N/CN/C
8354.846.6−15%
9313.0N/CN/C
104A12.47.6−39%
114A7.64.2−45%
124B7.5N/CN/C
134B6.41.2−81%b
144C44.828.3−37%
154C8.63.9−55%b
165A9.1N/CN/C
175A7.42.5−66%b
185B13.23.6−73%b
195B4.22.6−38%
205C1.40.7−50%
  • a N/C, no change.

  • b Patients who meet criteria for PR.