Table 1

Target genes in stomach tumors with MSI

Tumor casesAnalysis of microsatellitesTarget Genes
Bat26APΔ3hMSH3 (A)8ahMSH6 (C)8aCHK1 (A)9ahMLH3 (A)9aATR (A)10aMED1 (A)10a
Stomach tumors, percentage of positive casesb56% (13/23)43% (10/23)9% (2/23)0%21% (5/23)43% (10/23)
V1+c++u+d+d
V6++
V21+++d+d
V22+++d+u
V23+++d+d
V152+++d
V153+++d
V154+++d+d
V155+++u+u+d
V156+++u,uu+d
V157+++d
V158+++d
J53+++u,uu
J60+++d
J62+++d
J71+++d+u+d
J78+++d
J85+++d+u,d+d
J89+++d+u+d
J94+++d+d+d
J95+++d
J99+++d+d
J106+++d
  • a The size of the repeat.

  • b All tumors and tumor cell lines were negative for mutations within the DNA repair genes ATM (T)7, NBS1 (A)7, and BRCA1 (A)8.

  • c +, mutant; −, wild type; +u, 1-bp insertion; +u,uu, homozygous insertions of 1 and 2 bp; +d, 1-bp deletion.