Table 2

Correlation of genes down (A) and up (B) with changes of copy number as assessed by CGH and correlation of all mapped genes (c) down (⇓) and up (⇑) with change in DNA

Gene selection criteria are outlined in “Materials and Methods.”
DNA change per CGH
a?Total
A. Down groups
Criteria
 ≤0.5012115129
 >0.50–≤0.75 (in 5/5 arrays)21246556
 >0.50–≤0.75 (in 4/5 arrays)21177045
5452186130
B. Up groups
Criteria
 ≥2.0256011
 ≥1.7–<2.011111123
 ≥1.5–<1.741322136
71939277
C. Combined data
Genes ⇓545218
Genes ⇑71939P < 0.0001b
  • a ⇓, DNA loss; ⇑, DNA gain; ⇔, DNA neutral; ?, genes with imprecise mapping.

  • b Value of 2 × 3 χ2.