Table 4

Genes identified as down- or up-regulated from microarray analysis of BPH-1 to CAFTD 01 tumorigenesis, grouped by known or putative function

Shown are Unigene abbreviation, known or BLAST-mapped locus, mean ratio on microarray pairs, and change of DNA copy number (δDNA) at this region, as assessed by CGH (gain = ⇑, loss = ⇓, neutral = ⇔). A “?” indicates imprecise mapping despite Human Genome BLAST with GenBank sequence.
GeneMapRatioδDNA
Proinvasion
CSTA3q210.37
KRT 1917q210.48
CTNNA5q310.56
ITGA317q21-220.70
SPARCL1?7pter1.52?
MMP-920q11.22.03
KRT 712q12-211.96
CTSW11q131.80
Prosurvival
TRAIL3q260.54
CALM319q13.20.62
CDC 421p36.10.67
SARP28p122.56
RAC17p222.10
IAP1,211q222.1, 1.75
Progrowth
 Tumor suppressor genes
  TC2111p13-pter0.47?
  TSG10111p150.73
  SNX146q130.62
  BRCA117q210.72
 Oncogenes
  GRO1,24q212.9, 2.6
  RAB3A19p13.21.93
  cFOS-L-111q131.78
  PIM-16p21.21.54