Table 11

Tumor characteristics for primary breast carcinoma analyzed for GIRK1 expression

CaseGIRK1aCIbNo. of total LNNo. of positive LNAge (yr)Size (cm)GradeER
80500–0.07905211+
404600–0.03230521.13
9260.20.2–0.2180691.83+
23940.20.2–0.271005612
16470.30.2–0.380371.83+
60770.30.2–0.660544.51
18280.30.3–0.37130662.22+
25060.40–3.6220482.81+
24950.40.3–0.461204611+
39680.40.3–0.41105422+
9800.40.4–0.5805523
19140.40.4–0.6190640.91+
20970.60.5–0.690540.91+
18970.80.3–2.0120550.82+
12410.90.4–2.21308113+
17401.10.9–1.5220412.22+
67572.81.9–4.1150542.23+
62634.14–4.480300.92+
41494.63.8–5.560531.73+
41626.25.8–9.1190301.63
24688.67.3–10.1120704.82+
59908.68.6–10190591.42+
818.86.1–12.8130331.91+
594913.713.6–14.2140720.92+
618513.810.9–17.5190531.22+
643514.814.1–15.6110461.82+
939c27.425.6–31110661.72+
259137.932.3–44.51206812
146639.332.1–481006723+
4041142.5130.6–156140661.61+
21750.60.5–0.791711.51+
12900.70.5–181731.82+
25880.70.6–0.91314321+
73337.16.8–7.4181391.32+
62579.88.6–11.281341.33
3125145.5125.6–201.31516532+
5620186.1165–21081591.51+
46741.41.3–1.51025123+
5008148.1147.3–181112485.53
339335.5302.7–378.61425133
13750.930.7–1.17102293.61+
21510.10–0.173491.53+
58527.723.9–3283884.52+
723753.627.1–1191135922+
119167.666.3–70.1193590.92+
5893T282.1212.1–3752034352+
6370T0.90.7–1.2414462.53
4057704.3658–75454621.42+
38731.61.3–2.1216723.53
6619453.5350.1–5881166953
50.10.1–0.21187322+
410674.368–81.31286023+
586689.382.4–97158531.13+
215300–028135122
313027.325.8–292019464.43
68739.17.1–11.7272684123+
  • a Fold increase above control.

  • b CI (95% confidence intervals); LN, lymph node; ER, estrogen receptor status (as measured by immunohistochemistry); Grade, Bloom Richardson grade.

  • c Cases shown in bold overexpress GIRK1.