Table 2

Association of immunocytochemical staining for OPN with other tumor variables

Tumor variableaOPN-negative nob (%)OPN-positive nob (%)Statistical significancec
Grade 1, 268 (83)129 (70)0.024
Grade 314 (17)56 (30)
LN−49 (61)82 (52)0.17
LN+31 (39)77 (48)
C-erbB-3−68 (59)66 (31)<0.001
C-erbB-3+47 (41)146 (69)
p53−82 (71)125 (57)0.014
p53+34 (29)95 (43)
PgR−74 (68)124 (58)0.089
PgR+34 (32)89 (42)
pS2−81 (70)123 (57)0.025
pS2+35 (30)94 (43)
  • a Grade, histological grade 3 vs. histological grades 1, 2; LN, lymph node with tumor (+) or without tumor deposits (−); c-erbB-3, the presence (+) or absence (−) of immunocytochemical staining for the c-erbB-3 receptor (38) ; p53, the presence (+) or absence (−) of staining for p53 (38) ; PgR, the presence (+) or absence (−) of staining for the progesterone receptor (38) ; pS2, the presence (+) or absence (−) of staining for pS2 (38) .

  • b Number of patients with carcinomas either classified as staining (positive) or not staining (negative) for OPN. Parentheses show the percentage of patients.

  • c Probability, P between paired samples from Fisher’s exact test (two-sided value).