Table 5

Summary of the survival of OPN-positive patients divided into groups by the other tumor variables

Tumor variable (TV)Median survivala (months)Cumulative survivala (%)χ2bPbRRc95% CIc
TV−TV+TV−TV+
Tumor size T4d74.331.026.610.07.10.0082.431.36–4.33
Histol. grade IIIe78.954.728.220.92.00.161.350.94–1.95
Nodal statusf108.849.733.016.314.30.00021.991.35–2.93
C-erbB-2g82.540.129.013.312.60.00042.041.41–2.95
C-erbB-3g45.879.518.930.18.50.0040.630.44–0.89
ERαg51.6107.715.935.716.40.00010.500.36–0.71
PgRg57.599.423.130.67.60.0060.660.47–0.94
pS2g63.474.026.026.41.310.250.900.64–1.26
p53g78.755.720.932.31.120.291.050.75–1.46
Cathepsin Dg72.663.426.226.20.040.830.940.64–1.37
  • a Median survival in months and cumulative survival (%) of patients with OPN-positive tumors and either not expressing (TV−) or expressing (TV+) one of the other tumor variables.

  • b Wilcoxon statistic (χ2) and probability for 1 d.f. (P) for the significance of the difference of the other tumor variable for the OPN-positive patients.

  • c RR for survival and 95% CI were determined using a Cox univariate analysis for 1 d.f.

  • d Tumor size, not fixed (T1, T2, T3) vs. fixed tumors (T4).

  • e Histological grade (Histol. grade) of tumor, low (I, II) vs. high (III) grade.

  • f Nodal status, no nodes vs. 1 or more nodes involved with tumor.

  • g Negative vs. positive staining.