Table 1

Live virus was rescued from residual peritoneal tumors

Tumor nodules were disaggregated into single-cell suspensions. The cells (2 × 105) were plated in tissue culture plates for 48 h. Virus titer in cell lysates and CEA levels in media were determined. The presence/absence of syncytia in the culture was also assessed.

Mouse IDTumor weight (g)Final serum [CEA] (ng/ml)Virus titer (pfu/ml)[CEA] in media (ng/ml)Syncytia (presence/absence)
40.07<2.5<1<0.5
60.393454.8 × 1041900+
30.9014706.3 × 1042740+
51.1531456.3 × 1042890+
71.2948802.0 × 1054550+