Table 2

BRAF and RAS mutations identified in lung cancers and melanomas

BRAF exon 11BRAF exon 15KRAS2 exon 2NRAS exon 3
Lung cancer
Lung adenocarcinomaV458L (1)G12R (1)S65R (1)
K438T (1)G12A (3)
G12L (1)
G12D (1)
G12S (2)
G12F (1)
G12C (4)
A18T (1)
Lung SCCT439P (1)L596V (1)
V599E (1)
Lung poorly differentiated carcinomaG12L (1)
Lung neuroendocrine carcinomaS65C (2)
Malignant melanomaK438Q (1)V599E (19)S65C (1)
V599D (1)
K600E (1)