Table 1

Losses and gains of chromosomes

Cell lineChromosomen1234>4% off mode
Colorectal
 Stable (HCT116)Average of eight different chromosomes100 each4
 Unstable (HT29)Average of nine different chromosomes100 each51
 HCTp53HET71002944006
121000936106
 HCTp53KO.111000946006
151002960202
 HCTp53KO.21810001000000
 HCTp53KO.331002944006
181000982002
 HCTp53KO.4310001000000
1710001000000
1810001000000
X10010000000
 HCTp53KO.511003961004
71001963004
121000991001
151004942006
171002980002
X1009730003
Fibroblast
 FBWT71000904604
121001884705
171001913504
 FBp53HET1490926206
175088840012
181000945105
X502908008
 FBp53KO11002893605
39908521302
71047851708
121056862608
1711057621707
1810227441826
X11007802110