Table 2

Multivariate logistic regression analysis

OutcomeCovariatesOdds ratio95% CIP
PTEN
p-Akt0.13a(0.03–0.52)0.0043
p-mTOR0.54(0.061–4.80)0.58
p-FKHR1.10(0.24–4.60)0.94
p-S65.00(0.470–53.00)0.18
p-Erk0.88(0.092–8.30)0.91
Akt
p-FKHR3.80(1.30–11.0)0.015
p-s61.70(0.57–5.20)0.34
p-Erk0.64(0.11–3.7)0.62
EGFRvIII0.33(0.062–1.7)0.19
  • a Odds of a tumor being PTEN deficient if it is p-Akt positive are 7.7 times (1/0.13) greater than if it is p-Akt negative.