Table 1

Summary of statistical indices used to select candidate markers

A. Villin
Mean difference in expression log10 (ratio)aMedian difference in intensity levelsbP of t testc
PercentiledRankPercentileRankPercentileRank
Total genes (9706)0.0083 (0.83%)810.0093 (0.93%)910.018176
Sequence-verified genes (4047)0.0074 (0.74%)300.0091 (0.91%)370.017070
B. Moesin
Mean difference in expression log10 (ratio)Median difference in intensity levelsP of t test
PercentileRankPercentileRankPercentileRank
Total genes (9706)0.0073 (0.73%)710.0044 (0.44%)430.012119
Sequence-verified genes (4047)0.0099 (0.99%)400.0064 (0.64%)260.013052
  • a Difference = [mean of log10(ratio) for colon lines) − (mean of log10(ratio) for ovarian lines].

  • b Difference = [(median of single-channel intensity levels for colon lines) − (median of single-channel intensity levels for ovarian lines)]. Hence, the values are positive for villin and negative for moesin.

  • c Two-tailed P for the null hypothesis that there is no difference between the means of colon and ovarian expression ratios. The internal reference in each case is the cell pool, hence the expression ratios reflect relative colon-ovarian expression levels for villin and moesin.

  • d Percentiles and ranks were calculated using only the sequence-verified genes in the set (i.e., those not marked SID in the original database).