Table 2

Testes weight and sperm count in mice with conditional inactivation of the VHL gene and control littermates

GenotypeTestes Weighta (Mean ± SD) mgSperm Countb (Mean ± SD) × 106
VHLf/d/Cre90 ± 30c1.13 ± 0.95c
VHLf/d200 ± 4015.19 ± 6.45
VHLf/+/Cre230 ± 3027.08 ± 10.08
VHLf/+220 ± 3033.64 ± 4.99
  • a Testes weight data from 14–16 male animals for each genotype group.

  • b Sperm count data from 8–9 male animals for each genotype group.

  • c P <0.0001 relative to VHLf/+ controls; Student’s t test.