Table 1

Ras-inducible, NF-κB-regulated genes

Gene namegb identifierFold*Normalized fluorescent intensityP value
DKO-H-rasDKO-PUROp65+/+ PUROp65+/+ H-ras
Serpinb2 NM_01111133.321.0360.5110.98932.950.00936
Tslp NM_02136711.920.4910.791.22414.590.078
Adra2a NM_00747176.3391.0630.8970.8235.2170.00518
Tmod2 AK0182235.8951.6130.9040.8384.940.028
PCA-1 § BB5601775.6950.8840.941.0586.0250.179
Galactin7 AF0385625.5860.9210.7770.9725.430.0437
Posh NM_0215065.3150.7510.7430.8564.550.0231
PI4P5K-I BC0037634.8961.3070.9260.763.7210.207
Or10 NM_0205134.0220.8430.6551.0434.1950.00204
Psgl-1/Selp1 NM_0091513.9250.950.9650.8773.4420.00351
Aeg1 NM_0096383.8620.7251.0040.9563.6920.251
Pkp1 NM_0196453.7861.1510.840.7542.8550.242
Tage4 NM_0093103.7121.070.860.7682.8510.13
EST AV3024093.6840.9980.9050.7752.8550.0662
Nppb NM_0087263.5150.9950.9980.8312.9210.054
Stk10 NM_0092883.2280.8090.7961.0743.4670.021
Col18a1 NM_0099293.0450.9980.7670.9252.8170.179
Bsf3 NM_0199522.9991.1120.9490.9252.7740.0256
AldH1a3 § BC0266672.8090.8970.8470.9582.6910.227
Klf3 NM_0084532.6260.8030.8211.1112.9170.15
Adra2c NM_0074182.5970.9650.7781.0442.7110.0211
Cgref1 BC0231162.5011.0640.830.8872.2180.0112
Sox5 AK0152122.4660.8311.0230.9932.4490.14
RN19 § AK0159662.2560.8851.0210.9512.1450.0129
Oas16 AB0675302.0790.9291.1160.8561.780.248
  • Abbreviations: gb, GenBank; DKO, double knockout; PURO, (supplemented with) puromycin.

  • * Fold induction on response to H-ras expression in p65+/+ MEFs.

  • Normalization procedure is described in Materials and Methods.

  • t test P values for significance across two independent experiments involving independent Affymetrix chips.

  • § Gene name based on >80% nucleotide identity to Hs homolog.