Table 3

Risk associated with MPO polymorphisms among premenopausal and postmenopausal women consuming diets low and high in antioxidants: Long Island Breast Cancer Study Project, 1996–1997

Premenopausal Low ConsumptionPremenopausal High ConsumptionPostmenopausal Low ConsumptionPostmenopausal High Consumption
CasesControlsORCICasesControlsORCICasesControlsORCICasesControlsORCI
Fruit & Vegetable150180174176372338274315
GG88109111299122621611731741
GA53561.140.70–1.8553580.770.48–1.241191061.100.80–1.53881210.720.51–1.02
AA9150.780.32–1.929190.430.18–1.0027161.640.85–3.1713200.630.30–1.32
GG88109111299122621611731741
GA + AA62711.060.67–1.6862770.690.44–1.071461221.170.86–1.601011410.710.51–0.99
Fruit156180168176334332312320
GG991051101103120021011991801
GA50580.900.55–1.4656560.950.59–1.531111091.090.78–1.53961170.730.52–1.03
AA7170.460.18–1.1911170.660.29–1.5023131.790.88–3.6817230.650.34–1.27
GG991051101103120021011991801
GA + AA57750.800.50–1.2667730.880.57–1.371341221.170.85–1.611131400.720.52–0.99
Vegetable162194161158378347257297
GG95120110485122721611631681
GA55581.110.69–1.7951550.780.48–1.271251131.050.77–1.45801110.740.51–1.06
AA12160.980.44–2.216180.290.11–0.7726181.360.72–2.5814180.760.37–1.60
GG95120110485122721611631681
GA + AA67741.080.70–1.6957730.660.41–1.041511311.100.81–1.48941290.740.52–1.04
Carotenoids156178168178359328288326
GG93109110799121320511871851
GA52561.080.67–1.7554580.790.49–1.281241091.090.79–1.51831190.690.49–0.98
AA11131.020.43–2.427210.320.13–0.8122141.500.75–3.0518220.760.39–1.48
GG9310911079912132051187185
GA + AA63691.070.68–1.6861790.670.43–1.051461231.140.84–1.551011410.700.50–0.97
 Vitamin C171179153177325327322327
GG10210919899119620012041901
GA59571.080.67–1.7447570.780.48–1.281091120.990.71–1.38981160.790.56–1.11
AA10130.870.36–2.108210.410.17–0.9920151.330.66–2.6920210.860.45–1.64
GG10210919899119620012041901
GA + AA69701.040.67–1.6355780.690.44–1.091291271.030.75–1.421181370.800.58–1.10
Vitamin E158179166177338329309325
GG93109110799121719711831931
GA55561.140.70–1.8551580.770.48–1.251021140.820.59–1.141051140.960.68–1.34
AA10140.890.37–2.138200.400.16–0.9519180.910.46–1.7921181.220.63–2.39
GG93109110799121719711831931
GA + AA65701.090.69–1.7159780.680.43–1.061211320.830.61–1.141261320.990.72–1.37
  • Note. Low and high consumption are based on median values of control group. Premenopausal group: Fruit and vegetable, 25 svg/wk; fruit, 6 svg/wk; vegetable, 14 svg/wk; carotenoids, 5,610.34 mcg/d; vitamin C, 106.74 mg/d; vitamin E, 6.92 α-TE/d. Postmenopausal group: Fruit and vegetable, 32 svg/wk; fruit, 10 svg/wk; vegetable, 16 svg/wk; carotenoids, 6,145.95 mcg/d; vitamin C, 115.54 mg/d; vitamin E, 6.80 α-TE/d. ORs and 95% CIs are calculated by unconditional logistic regression, adjusted for age, family history, and number of pregnancies.

  • Abbreviations: svg, serving(s); α-TE, α-tocopherol equivalents.