Table 1

Representative example of genes differentially expressed in H1299 cells overexpressing the p53R175H mutant

NameAccession no.Fold change
Down-regulated genes
 Human succinyl CoA:3-oxoacid CoA transferaseU6296113
 Human annexin III (ANX3)L205913.5
 Fibronectin receptor α subunitX062564.5
 Human interleukin-13 receptorU7098114
 plasminogen activator inhibitor type 1X047297.5
Homo sapiens galactocerebrosidase (GALC)L231168.4
H. sapiens glycogen synthase kinase 3L400272.5
 A-myb = DNA-binding transactivatorS758812.5
 MHC-encoded proteasome subunit gene LAMP7-E1Z149822.6
H. sapiens hbrmX728893.6
 Human transforming growth factor-β–induced gene product (BIGH3)M773492.6
 Urokinase-type plasminogen activator receptor geneU099373.4
 Human MESTD786113.7
 Human insulin-like growth factor binding protein 6 (IGFBP6)M624029
Up-regulated genes
 Human down syndrome critical region 1 (DSCR1)U852677.5
 Human aldehyde dehydrogenase 6U079192.7
 Zyxin 2X957352.5
 AdrenomedullinD148742.7
 Asparagine synthetase mRNAM273962.7
 Human NF-IL6-β proteinM836673
 Human heparin-binding EGF-like growth factorM602783
 Aldose reductaseX154143
 Human skeletal muscle LIM-protein SLIM1U601153.7
H. sapiens NF-H geneX153064.5
 FibronectinX027616.5
 Elongation factor 1 α-2X709403
 CalretininX566674.7
 Homeotic Protein Gbx2HG31235
 Human heparin-binding EGF-like growth factorM602784.4
 Early growth response protein 1 (hEGR1)X5254115
 Oncogene c-fosV0151223