Table 2

CYP1B1-specific staining of normal human endometrium during proliferative and secretory phase

Staining of glands in the functionalis was evaluated as positive when >10% of the constituting epithelial cells in a gland were stained. The results were judged by three independent pathologists as − (<10% of the glands at the region of interest), + (>10%), or ++ (>10% with high intensity). The statistical significance of differences in the extent of staining in the different phases of the menstrual cycles was tested by Fisher’s exact method (P < 0.001).

Menstrual phaseStaining of glandular epithelial cells
+++
Proliferative (n = 11)650
Early secretory (n = 5)230
Late secretory (n = 3)003