Table 1.

Peripheral blood cell counts in mice treated with normal IgG or anti-CXCR4 antibody

TreatmentCancer cell typeRBC (×10,000/mm3)Hemoglobin (g/dL)WBC (/μL)
Normal IgGColon38878 ± 3314.3 ± 0.523367 ± 376
Anti-CXCR4Colon38901 ± 28NS14.5 ± 0.35NS3200 ± 173NS
Normal IgGPancO2802 ± 4614.2 ± 0.182233 ± 376
Anti-CXCR4PancO2853 ± 38NS13.8 ± 0.45NS3133 ± 286NS
  • NOTE: Peripheral blood cells were counted on day 14 after tumor inoculation (n = 3 for each group). NS, not significantly different versus normal IgG-treated mice.