Table 3.

ABCG2 and tumorigenesis

SamplesCell injected (n)IncidenceLatency (median), d
U373-unsorted1,0003/326
10,0004/419
U373-ABCG2+1,0008/830
10,0002/226
U373-ABCG21,0004/419
10,0003/419
100,0004/419
Du145-unsorted1003/577
1,0004/653
10,0005/645
100,0004/435
Du145-ABCG2+1003/881
1,0002/680
Du145-ABCG21002/673
1,0001/663
10,0002/655
Du145-ABCG2+ *1002/6101
1,0001/263
Du145-ABCG21002/678
1,0002/654
10,0001/454
MDA-MB435-unsorted1004/667
1,0004/664
10,0002/461
MDA-MB435-ABCG2+1007/857
1,0003/447
MDA-MB435-ABCG21006/857
1,0003/457
10,0005/652
  • * Cells in this experiment were purified from the Du145 xenograft tumors. Cells in all other experiments were purified from cultured cells.