Table 3.

Clinicopathologic characteristics and EGFR mutation status of 13 NSCLC patients

CaseAge, yGenderSmoking statusHistologic typeECOG PSSerum amphiregulinSerum TGF-αEGFR mutationResponse to gefitinib
169FemaleNeverADC1NegativeNegativedel E746-A750PR
266FemaleNeverADC1NegativeNegativedel E746-A750PR
357MaleNeverADC1NegativeNegativeL858RPR
464MaleFormerSCC1NegativePositiveNDPR
564FemaleNeverSCC0NegativeNegativeL858RSD
653MaleCurrentASC1NegativeNegativeNDSD
747MaleFormerADC0NegativeNegativeNDSD
848FemaleNeverADC1NegativeNegativeNDSD
946MaleCurrentADC0NegativeNegativeL858RPD
1053MaleFormerADC1NegativePositiveL858RPD
1159MaleFormerADC2PositiveNegativeNDPD
1280MaleNeverSCC2PositivePositiveNDPD
1369FemaleNeverADC0NegativeNegativeNDPD
  • Abbreviation: ND, no mutation was detected.