Table 3.

Cell cycle measurements of NSCLC cell lines sensitive or insensitive to EGFR inhibition

NSCLC cell lineG0-G1G2-MSClassification
H29234.9 ± 2.427.8 ± 0.415.6 ± 0.1Sensitive
H32236.1 ± 1.431.8 ± 1.112.5 ± 1.8Sensitive
H35846.3 ± 1.920.2 ± 1.627.2 ± 2.1Sensitive
H44130.6 ± 1.931.1 ± 0.116.7 ± 0.2Sensitive
A54941.7 ±0.927.0 ± 0.722.3 ± 0.7Intermediate
H46051.3 ± 1.522.5 ± 1.414.5 ± 1.5Intermediate
Calu624.6 ± 0.833.0 ± 1.719.1 ± 0.6Insensitive
H170346.6 ± 1.919.5 ± 1.422.5 ± 1.2Insensitive
SW157372.2 ± 1.108.8 ± 0.315.3 ± 0.3Insensitive
  • NOTE: The percentages of cells of in G0-G1, G2-M, and S phases of the cell cycle were measured by FACS. SEs from two independent biological experiments are indicated. No correlation between cell cycle status in vitro and sensitivity to EGFR inhibition or epithelial versus mesenchymal phenotype was observed.