Table 1.

Constitutive and inducible expression of B7-H1 on mouse tumor lines

Cell lineTissue typeStrainB7-H1 expression
Constitutive *Inducible
J558PlasmacytomaBALB/c++
Sp2/0MyelomaBALB/c+>+
P815MastocytomaDBA/2>−>−
EL4ThymomaC57BL/6>−>−
C3Epithelial tumorC57BL/6>−>−
4T1Breast cancerBALB/c>−>+
AG104ASarcomaC3H/HeN>−>+
EMT-6Breast cancerBALB/c>−>+
  • * Constitutive expression of B7-H1 was determined by indirect immunofluorescence and flow cytometry analysis using mAb (clone 10B5) against mouse B7-H1.

  • The indicated tumor lines were cultured overnight in the presence of recombinant IFN-γ at 200 IU/mL before staining by 10B5.