Table 1.

Clinicopathologic and molecular characteristics of 22 cases studied

CasesAgePathologyRadials (%)
OSEPBMLFANCD2 expression (OSE)
MMC/DEBMMC/DEB
Normal
    OV-NL162ROV: no abnormalities0/0NDNormal
LOV: endometriosis
    OV-NL251Uterine fibroids. Normal ovaries0/0NDNormal
    OV-NL340Metrorrhagia. Normal ovaries2/00/0Normal
    OV-NL454LOV: no abnormalities4/1NDNormal
ROV: benign serous cystadenoma
    OV-NL568LOV: fibroma1/1NDNormal
ROV: no abnormalities
    OV-NL6L43CIN III. Normal ovaries0/00/NDNormal
    OV-NL6R0/00/ND
    OV-NL754LOV: benign serous cystadenoma1/2NDNormal
ROV: no abnormalities
    OV-NL855Uterine polyp. Normal ovaries3/3NDNormal
    OV-NL9L48Uterine fibroid. Normal ovaries0/00/0Normal
    OV-NL9R0/00/0
High risk
    OV-HR130No evidence of multifocal surface papillomatosis, pseudostratification, or activity of the epithelium or ovarian stroma in any high risk sample10/140/0Normal
    OV-HR27150/640/0Reduced
    OV-HR34364/551/0Normal
    OV-HR4L3566/500/0Reduced
    OV-HR5L7147/200/1Reduced
    OV-HR5R30/120/0Reduced
Carcinoma
    OV-CA172Poorly differentiated serous carcinoma, stage IIIC14/162/0Normal
    OV-CA252Poorly differentiated serous carcinoma, stage IV12/101/0Normal
    OV-CA363Moderately differentiated serous carcinoma, stage IIIB16/141/1Normal
    OV-CA470Poorly differentiated serous carcinoma, stage IIIC70/484/2Reduced
    OV-CA554Poorly differentiated serous carcinoma, stage IIIC12/22/0Normal
    OV-CA673Poorly differentiated serous carcinoma, stage IV66/ND1/1Normal
    OV-CA758Poorly differentiated serous carcinoma, stage IIIC0/ND0/1Normal
    OV-CA862Poorly differentiated serous carcinoma, stage IIIC33/ND3/1Normal
  • Abbreviations: LOV, left ovary; ROV, right ovary; CIN III, cervical intraepithelial dysplasia III; ND, not determined.